ZMP

si:dkeyp-2c8.2

Ensembl ID:

ENSDARG00000035273

ZFIN ID:

ZDB-GENE-081031-100

Description:

Novel protein similar to vertebrate transmembrane and tetratricopeptide repeat containing 2 (TMTC2)

Human Orthologue:

TMTC2

Human Description:

transmembrane and tetratricopeptide repeat containing 2 [Source:HGNC Symbol;Acc:25440]

Mouse Orthologue:

Tmtc2

Mouse Description:

transmembrane and tetratricopeptide repeat containing 2 Gene [Source:MGI Symbol;Acc:MGI:1914057]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa2958	Essential Splice Site	F2 line generated	Not yet available
sa36585	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa2958

Status:

F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000051105	Essential Splice Site	495	837	3	12
ENSDART00000133762	Essential Splice Site	252	594	1	10

Genomic Location (Zv9):

Chromosome 18 (position 11307505)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	18	11890435
GRCz11	18	11859153

KASP Assay ID:

554-2748.1 (used for ordering genotyping assays)

KASP Sequence:

GAATGAGGAGATGCTATAYAAGTCAGGGATATCTGTGAACCCTGCCAAAG[G/A]TAATTATGAGATTGCAATACACAATACGTCTGAAGATACCAATCTTTGCT

Long Flanking Sequence:

ACTTCACCTTTACCCAACAAAAAGCAAAGAAACCAATGGTAAAGCCCATCATGTAGCAAATGGAAAGTCCTCAAATGGACACAGTTGTAGCACTGACTATGAAAACTCAACTTTCTACTCAAACTCAGTGCAGATGAATGGAACAAATGGTACTGTAAAGCACTATTCATCATCTTTACCCACTACTGAAAGTTTGGTGGTCTTTTCATTGGGTTTATTAGCCATTCCTTTCATCCCAGCCACCAATCTGTTCTTCTATGTTGGTTTTGTGGTGGCCGAGCGAGTGCTGTACATTCCTAGTATGGGCTACTGTCTGCTGGTGGCTTTAGGAATGAGGTGTTTATATGTCCGACTAAGGAGAAAGTCCTCTAGAACGTTGGTGTTGGGCTGCTCTGCTGCGCTGGTTCTTCTCTTTGGAATTAAGACGGTGTTGAGGAACCGAGACTGGCAGAATGAGGAGATGCTATACAAGTCAGGGATATCTGTGAACCCTGCCAAAG[G/A]TAATTATGAGATTGCAATACACAATACGTCTGAAGATACCAATCTTTGCTTTAGCAGTCCAGATTGTTCTCCGACCAGGAGTTGTTCTAGTGTCATTAGTGTATGTTTATGGTTTGATGGATTGATATTTATTTATTTATTTATTCATTAATTCATCCAAAATATATGTAAATGTATTGCACTGCTACAAGTGTAATATTGCTTTTATATAACAGTTCAATGACGTAATTGTGTTTATAAAAAAAGAAAATCAAACACGGAGAGTCTCAAAAGCTCCTTGGTAAGAGGAACTACTTTCTTCCGCCATTCATACACATCTGCAGCTGACGCCAGAGCAGCAGTATTGTTACTAAGTTACAATGTCACTTTAGAGCTAGTATTTGAATGATTCTCTAATGTAATGTCTAAAGTTATGACGAAACAGGTGATTTTGCTCACAGTTTAAGATCATAAGGCTGAACGGCATGAAAAGACATCAATCTACAGAGATTTCCCACACT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa36585

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > G

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000051105	Essential Splice Site	691	837	8	12
ENSDART00000133762	Essential Splice Site	448	594	6	10

Genomic Location (Zv9):

Chromosome 18 (position 11327087)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	18	11910017
GRCz11	18	11878735

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TGACCATATACCTGCACACCTCACATACGGCAAGCTCCTGGCTATGACGG[T/G]AAACAAACACAATAACCCACACTGAAAGAAAAAGCGCTTGAGTTGTTTAG

Long Flanking Sequence:

ATGTTTAGAAATGTGTTAAAAAAATCTCCTCTCTGTTAAACAGAAATTGAGGAAAAAATAAACAGGGGGGCTAATAATTCAACTTCAGCTGTATACTTTATGCTCATTATTATATACTACAAATACTGTTAAATAAATCTAATCTAATGAAAAATAATCTCTTTAATAATTAATGCTTATCTTCTGGTCAGTAAGCAATAACCAGCTACATGTTGGTTTCACTCCAGTATCCAATTTCATGAAGTGTTGATTTTTTTGTGGTTTGTTTTCAGTTGACTGCCTTCATTTCTGCTGTGGGATGAAGCACGGCGCAGGGCTGGTTATGTGCTTCTTTAACTTCTGACCTGTTGACCTGACCTCTGTCTCGTGTCTCACAGGAGAGGCCTTCATGAGGCTGAACAAACTCACGGAGGCAGAACACTGGTATAAAGAGTCCCTCCGAGCCAAACCTGACCATATACCTGCACACCTCACATACGGCAAGCTCCTGGCTATGACGG[T/G]AAACAAACACAATAACCCACACTGAAAGAAAAAGCGCTTGAGTTGTTTAGCTATAAATATTTAGACAGAGGTTTGCCAGTTTGAACCTTGGGAAATAAAATCCAGGAACTTTGCCTTGCTCAAAACCTTGCTGAAAATGAAATCATTATTTAACATCCTTTGTGTTGTTCTAAAACAGGGGTCCCTGCAGGTTTTAGCTCTAACTTGCCTCAATACACTGTGTTTCAAGTATATCTAGTAAGACCTTGATTAGCTTGTTCAGGTGTGTTTAATTAGGGTTGGAGCTAAAATCTGCAGGACACCGGCCCTCCAGGAATAAGTTTGGTGACCCCTGTTCTAAAACATTTGACTTGCAGTACTGAAAGCTAAATGCACCAGCTTGACTTGTAGGATGATGATGGCTCTACATACAGTTTTTTAAATTACTGTAATCTGTGAGAGTTAAGAAATATAAATATTGAGTAAATTACCTTTAAAGCTATTCAGATTAAATGCTTAGC

Associated Phenotype:

Not determined