Busch Lab

ZMP

tgfb3

Ensembl ID:
ENSDARG00000019367
ZFIN ID:
ZDB-GENE-030723-4
Description:
transforming growth factor beta-3 [Source:RefSeq peptide;Acc:NP_919367]
Human Orthologue:
TGFB3
Human Description:
transforming growth factor, beta 3 [Source:HGNC Symbol;Acc:11769]
Mouse Orthologue:
Tgfb3
Mouse Description:
transforming growth factor, beta 3 Gene [Source:MGI Symbol;Acc:MGI:98727]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
hu3526 Nonsense Available for shipment Available now
sa1467 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
hu3526
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000019766 Nonsense 181 410 3 7
ENSDART00000147600 Nonsense 66 295 2 6

The following transcripts of ENSDARG00000019367 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 17 (position 52599463)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 51999649
GRCz11 17 52070328
KASP Assay ID:
554-0143.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TACGTGTGTTTTTACGGCAGATTCTCCGTCCTGATGAGCACATCGGCAAG[C/T]AGCGCTACATCGGCAGAAAAAACGTGATGATTGGAGGGACGGATGAGTGG
Long Flanking Sequence:
AGTGTGCCATTTGGGACGACACTACATACATATACTATCCTGTTGAGTGTGTATGTGCATAGTGCATGATTGCATAGTGTATAGTGTGCAATTTGGGACGCAGCTCTAATTTTACATTTTATGATTCTGCAAGTGAATCTGGTGATGAAACAGAATAAATAGCGAGTTAATAAGAGCACAAAGCAAACAGTAAGCTTGCTATTGTCAACATTTCTAGTTTTACAATTCTGACTTTTGTCCACAAAATATTGAATTTACAGTACACGGTTTCCTCACGATTGTTTTTAATTTGTGCTCTAAAATGTAAAAAATATAAGCAGGGCTTGAAATTACCCTTTTTAAGTGCCCATGATGTCAATGTTGTGTTTATTACCACAATATATCGCATTATTGAATATCTCCACATGTCTAATCATGGATGTTGATTAATGGAGAGCAGAAATCAGCTTTTACGTGTGTTTTTACGGCAGATTCTCCGTCCTGATGAGCACATCGGCAAG[C/T]AGCGCTACATCGGCAGAAAAAACGTGATGATTGGAGGGACGGATGAGTGGGTTTCCTTCGACGTCACTGAGACCGTACGAGAGTGGCTGACAAACAGAGGTCAGTCCCATTTAACACTTTAAACTCATCGGAAAGACTCTGGTGTTTTTATTACAAGACTTTTGAACTGTTTTGAACTCTTATGCGATGATTAAAATGGATCCTTTTCACATTTCTGGGTTTCTCAGGAGCGGAAGTCAGCATAGTTGGTGAACTCAGAGCGCAGTGAATGGCAGAGTACAACAAATCGTTTGTTTACAATCCTATTTACTGAAATAATGAAAGAAAAACTCAGACAACAGTGTTGTCAAGACTATATTCAACAATCAAGACTAATATGAAATGTAAATTTTACCAGCATATAAAAATTCAGATTTATTAAATTACAATATTCAAATTCACACAGTTTCAGTTCAGGTTGTTTTGGCATATTATTAGCTCCATAGTGTTGTGATCTCAGT
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa1467
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000019766 Nonsense 379 410 7 7
ENSDART00000147600 Nonsense 264 295 6 6

The following transcripts of ENSDARG00000019367 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 17 (position 52588253)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 51988439
GRCz11 17 52059118
KASP Assay ID:
554-1392.1 (used for ordering genotyping assays)
KASP Sequence:
TGTACAACACGCTGAACCCRGAGGCGTCTGCGTCCCCCTGCTGCGTTCCT[C/T]AAGACCTGGAGCCGCTCACCATCCTCTACTACGTGGGCCGGACGCCTAAA
Long Flanking Sequence:
TCAAGAATCAGATCTAGACTAACCATAGAGTATCCAAGACCTAGACAAAACCACACAAGACTCAAATTCTAAGACTAGACCATGAAGACCCATATCCAAACCAAGACTTGCCCCTTCAAGAACCAGATCTAGACTAACCAAGACCCAGATTAAGATTAGACGCCTCAAGACCCAGATGCAGACTAAGACTAAACAGACTACGGGCGTGTGTCCACTGAAGCACCTCTTTGCTGCAGCACAAAATGCTTCGGTGGTCGTGCATGCACCCTAAGACTAAACTCTGGAGAACCTCGAAGCTCTCCGCTTTCATCTAGAATATCTTGACTCATGTTCTGAAGATGAGCTTGGTCTCAGGGAGTTTGTGAAGCTGAATGTGTTTTGTTTGATGATGATGATGATGATGAAGATAATTTGACGTGGGCTCCTTCATGTGTGCACAGCTGCTGAGTCTGTACAACACGCTGAACCCAGAGGCGTCTGCGTCCCCCTGCTGCGTTCCT[C/T]AAGACCTGGAGCCGCTCACCATCCTCTACTACGTGGGCCGGACGCCTAAAGTGGAGCAGCTTTCCAACATGATCGTCAAATCCTGCAAGTGCAGCTGAGAGGTCCGTTTTCAACCCATCCACGAGCCAAAAGCTTCTGCGTTTTCAGACCAGCCAAAAGGCCACACGACCATCCCTCAGACTTCCAGACCTTTAAAGTGACCTGTAGCGTGTAATGTTCGGTCCGCTCTTTTAAACCTCATGGGCATTTCTGAACTCTGGAGCTCCATGGAAGATCTACAGACGGAGCTTTACTGAGATCCCACACATGCTGGAGCCACGGATGGGTTCAACCAGCGTTTCTGTACAACGTAATGATTCTTTTGTTCCTCCAGACTGTTTAAAGTGTGTACCACAGTAACTCGCACTGTCTAATGGGTTTTTTTTTTGTTAATACAAACATGCTGGAAAGAGAAAACATGGTGTTTGGCCTTGGTTATGTTTACCTCTGTCACACGGCAG
Associated Phenotype:
Not determined