ZMP

lck

Ensembl ID:

ENSDARG00000059282

ZFIN IDs:

ZDB-GENE-040617-1, ZDB-GENE-040617-1, ZDB-GENE-040617-1

Description:

lymphocyte-specific protein tyrosine kinase isoform 2 [Source:RefSeq peptide;Acc:NP_001035418]

Human Orthologue:

LCK

Human Description:

lymphocyte-specific protein tyrosine kinase [Source:HGNC Symbol;Acc:6524]

Mouse Orthologue:

Lck

Mouse Description:

lymphocyte protein tyrosine kinase Gene [Source:MGI Symbol;Acc:MGI:96756]

Alleles

There is 1 allele of this gene:

Allele Name	Consequence	Status	Availability
sa410	Nonsense	Available for shipment	Available now

Mutation Details

Allele Name:

sa410

Status:

Available for shipment
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Availability:

Order Allele From ZIRC

Mutation:

G > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000082356	Nonsense	120	503	5	12
ENSDART00000105478	Nonsense	120	503	6	13
ENSDART00000126663	Nonsense	120	503	6	13

Genomic Location (Zv9):

Chromosome 17 (position 25162106)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	17	25353797
GRCz11	17	25372188

KASP Assay ID:

554-0269.1 (used for ordering genotyping assays)

KASP Sequence:

CTCAAATGAAGTGAAAACTCTAATAAAATGACATCGTTGTGTTGCAGGTG[G/A]TTCTATAAAAATCTCTCCAGGAATGACGCCATGAGGCAGTTACTGGCTCC

Long Flanking Sequence:

TGATCCTGAATGGTACATGGCGGAGTCTCTGTTCACCGGCCAGAGGGGTTACATACCAAAGAACTTTGTAGCAAAACTGAACAGCATGGAGACAGAACCGTAAGTAATGCAATGCTCACTCGCATACAGTCACATACACCCAAACAAATACACACAATTAAATGTATTTATGCAGATGAAATCATCAGAATGACGTCTGGGAAATACCACCCACTTCAGTGGCTAAAATGTTTCACTTAGGATACCCCTTACCCACTTATGAAGACAGATGATCAAGAAGTCAGTAAAGAAAAAAAAATACTCCCACAAAACACACACGTTTCTGAGCATCGCTATGTTTAACCACTGCAGTAGCTGCTGACACCACATTTCTGCGTTAAGTTCCAGTCTGTGAATGTTTCTCTTCCAATCGTGGGAGGAGTGAAAAGCACCAAGTCTGAATTTCTGTAACTCAAATGAAGTGAAAACTCTAATAAAATGACATCGTTGTGTTGCAGGTG[G/A]TTCTATAAAAATCTCTCCAGGAATGACGCCATGAGGCAGTTACTGGCTCCTGGCAACACACAGGGCTCGTTTCTCATCAGAGAGAGCGAGACGCAGCCAGGTAGCCTTGCACTTTTCCCCACAACAACAACAAACTAAAAATGTACAGTATTATAAGGGCACATCTGACAGTGCTATCACATTATGGCTTTGATATCTTTCTAGATTTAAATATGAAAGTTAAACTAAATGTAAAAAATTTATGTAATTTTTATAAATAAACAACAGTAAGACATATTATTAATGATATAAATAATGCATTTCTGCTTTTTCAATTCTATACCCAGCTCATCTCAGCTATAATTAATGCATTAGCATTGTTATGTAATTTTGCATATTAGTTATTATTAATATCTTAATAAATATATTAGGTCACACTTTATTTTGATGGTTCGTTGAATTTAAGCTACATTGCATCTACATGCCAGCTATATCTCATTAGATTATAAGTAGACTGTTAG

Associated Phenotype:

Normal

Stage	Entity	Quality	Tag
Larval:Day 5 ZFS:0000037	whole organism ZFA:0001094	quality PATO:0000001	normal PATO:0000461