Busch Lab

ZMP

Q1LYC1_DANRE

Ensembl ID:
ENSDARG00000071357
Description:
Novel protein similar to vertebrate mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3)
Human Orthologue:
MAP4K3
Human Description:
mitogen-activated protein kinase kinase kinase kinase 3 [Source:HGNC Symbol;Acc:6865]
Mouse Orthologue:
Map4k3
Mouse Description:
mitogen-activated protein kinase kinase kinase kinase 3 Gene [Source:MGI Symbol;Acc:MGI:2154405]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa12892 Nonsense Available for shipment Available now
sa36410 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa45607 Nonsense Mutation detected in F1 DNA Not yet available
sa36411 Nonsense Mutation detected in F1 DNA Not yet available
sa18499 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa12892
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000093004 Nonsense 3 864 1 33
Genomic Location (Zv9):
Chromosome 17 (position 24460604)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 24614046
GRCz11 17 24632447
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GAAAACGTAAATAAACCGGAGGGCGCAAACGGTGACTCGCACGATGAATT[T/A]AAGCTTGGATCTATCGCGCAGAAACCCACAGGAGGACTTTGAGCTGATCC
Long Flanking Sequence:
CGTTTTGAAAAAAATAAGTATTAAAGTTAATATGTAATTAGTTTAAGGTAATTATGTCAGCTTAATTATTAGTTAACAACCATGTTCTGCCTAAGTTATGTGTCCCCTGAATAATAACTGCCTATATTTATTATAATTTAGAAGCTGTTTTGTTTTAAACAAGTTTTGTTTAAAACGATTAGTTCGTGTTGTCTTTCTTTATTGAAATGAAGTGATTTTATATGTATTAAAGTGAAATAGATCCATTATCAGCGTTTCTGAAGTTTCCCGGTGTCTTTCTGCTTCATTATGTACACATTTCTCTCCATCCTCGGTACGTGTTGTCAGTCAGTCGTACTGCGCATGCGCAGAGGAGGCCATGTTGTTGTAGTTCGGTGGGACTGGACCGTCATATCCCATCGTTACTGTATGTCTGTGCGATCATCACCCCCCTCCCGTTTTTGACATCGGGAAAACGTAAATAAACCGGAGGGCGCAAACGGTGACTCGCACGATGAATT[T/A]AAGCTTGGATCTATCGCGCAGAAACCCACAGGAGGACTTTGAGCTGATCCAGAGGATCGGGAGCGGAACCTATGGGGATGTATACAAGGTAGAGATCAACTGGGTATCAGAACCTAGCAAGCTACCTACCTAGACTGCATATTTGTACACCATAGGCGCTTTTTTCAAAAGGAGAGAATGCGCCTGTGGTGCCCGAAAACGCTGTCTTCTTAGGGAGCTCACTAGGGATTAAGACACAGCCACTTAACTGACCAATGAACCAGTGTGTACGAGAGACAACAGATGTGTGTTTACACCGGACCGCAGTGTATTTGTGTTCTGTAGCAATTTTGCGGCTAGGATGTGGTGTAATATCCTGAAAGACTCTGAAGATCTTTGTTTGCATAATGCACACGGCCTAGCAAGTCTATTTCATTAGAGAAAGCCAGTGCTAAGCTGTCAGATTCACATCTTCCATCTTTTTATGTGATGTACGTGACATAAACAAAGACAAGAGTAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36410
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000093004 Essential Splice Site 153 864 7 33
Genomic Location (Zv9):
Chromosome 17 (position 24468971)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 24622413
GRCz11 17 24640814
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGCAGGGTGCAAATATACTGTTAACAGACAACGGCTATGTTAAGCTAGG[T/A]AACAAAACACATTTATTGGAGATCACAGTTATTCAGAAGCACTAACCTTT
Long Flanking Sequence:
CATAATTAGCACTCATGAGAATGGAGAAGAGGATGTTGTTCTTAAAATAGAAATATCAATGAATAGATATTTTAACCGGACAATTTCATTAGATTTAATCTTGTAATCACAAATATTTGCACAAGACCAAAACATCCTGAATGCCTGTGGAATAAATGTGATTGTTCTTAAGTGTCTGTGCATGAATACACTGAGCGATCATTGTATTGACAACAAAAATACATGGTTTGTTTGTGCATCAAAGGGACTTAAACGTACTTATTTTACGACTTCTGTTTGTCACTGTAACCTTGAATACAATTCTCATCTTTCAAAGCTTTACTAGCAAGACCTTTAAGTTTTCTTTATCCAGCTCAGATGTCAGTCTGAATCAAATATTATGTCTCATCAGAAATGTAGATTTAAAGAGTTTGCTCATTTACAGCTGCTCATATTGGTTCTACTCTTGTTTTGCAGGGTGCAAATATACTGTTAACAGACAACGGCTATGTTAAGCTAGG[T/A]AACAAAACACATTTATTGGAGATCACAGTTATTCAGAAGCACTAACCTTTCCTTTCTAACATCTTTCGTCTGTCTCTGTCCAGCTGATTTTGGCGTTTCGGCTCAGATTTCAGCCACTTTAGCAAAAAGAAAGTCCTTCATTGGAACTCCATATTGGTATGCCAGTCCTTTCTCATTCTAATAGTTTTCTTCTAGTTGTTAAATTGCAAAAATTAATTTCTCTACACTGTGTGTGTTTCTCTGCAGGATGGCACCTGAAGTGGCAGCAGTGGAGCGGAAAGGTGGCTATAATCAGCTGTGTGATATTTGGGCTGTGGGCATCACAGCTATTGAGCTGGCGGAGTTGGAGCCACCAATGTTCGACTTGCACCCTATGAGGTGTGTTTCCAGTGACTTGGACTGATTTAAAGTCTCTCTGCTAAATTTTGTGCTAAATTAATTGACTAATTCCATAGTTTAAAGATATTATAGGCCATGTTTTATGTGACAGGGCTGCACAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa45607
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000093004 Nonsense 593 864 25 33
Genomic Location (Zv9):
Chromosome 17 (position 24484658)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 24638100
GRCz11 17 24656501
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCATGAAACTCTATACACTTCTATGTGTGTGTTTCACAGGTAAAGCATCT[C/T]AGCTGTACTCCTACAACCTGACGGGGCTCTTTGAACAAGCGCGACAGATG
Long Flanking Sequence:
TGTATGAGAGTGTGTGAACAAGTGTGTATGGATGTAAAACATATGCTGGATAAGTTGGCAGTTCATTGCTATGGTGACCCCTAAATAAAGGGACTAAGCTGATGGAAAATAGATGAATGAATGATATCAAAATAAGAAATAGTGTATAAAGTCTTGGCGATTCAAAATATGAAGATCAGTTAGTCAAATTTTTTATATATAATAAATATTTTGCCTTCACTTTAAAAATTCAAGAGAGAACAGACTATGAGAAACAAAGATTTCCATAAATATTTTAAATGTATGACAATTGATTTTTTTTTCATTCTTTAAATCTCATGCAGCTGGTTCCACGGCGGTGCACATGGGTTTATGTAATGAACAACTGGCTGCTTTCTATATCAGGTCAGATAAAACCAAAGAAAACATTTACCGAGCATTCCAGAATATTTGAATGTTTCAACTTCTCCATCATGAAACTCTATACACTTCTATGTGTGTGTTTCACAGGTAAAGCATCT[C/T]AGCTGTACTCCTACAACCTGACGGGGCTCTTTGAACAAGCGCGACAGATGCAGAAGTTACCCGTTGCCATTCCAACACACAAACTCCCAGACAAAATCATCCCGCGGTAAGATTTAGATCATAGATGTTAAAGTCAATTCCTGGAGGGCCGCAGCTCTGCACAGTTTTGCTTCAGCCCTAATCAAACACACCTGATCCAACTAATTAAGGTGTTCAAAAGAGTCTTGAACACCTTGACTAGTTGCATCAGCTGTGTTTGATTAGGGTTGGAGCAAAACTGTGCAGAGCTGCGGCCCTCAAGGAATGGAGTTTGACAGCTATGATTTAGATGAAACGTTTTAGGATCGTTTTATAAATTTAATCAGTTATCATTCATACTATTTTTTAAAATTTGATTTATCTAAAGATTTACTTAAATAATTGTGACTGATTTACAATGTGTTCCATTAATGCATTTGTTTCAGGAAGTTTACCGTGTCTAATAAAATACCAGAAACAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36411
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000093004 Nonsense 652 864 27 33
Genomic Location (Zv9):
Chromosome 17 (position 24486353)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 24639795
GRCz11 17 24658196
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATACAGTTTAACATGAATTGTTTGTGTATGTATGTAGTGCGAAACCCGTA[C/A]ACAGGTCACAAGTACCTCTGTGGAGCTTTCCAGTCCAGTGTAATGCTGTT
Long Flanking Sequence:
CAGAGTGTGGACCAAAAGTGCTAGTGTGAAAGCACCCTTATTAACTTATTTTTAAATAACTAATTTCTGTTGTCTTTGCCATTATGACAGTATATAATATTTCACTAGTTATTTTACAAGACTTTTTTCAGCTTAAAGTGCAATTTAAAAGGCTTGACTAGGTCAATTTGGTTAACTAGGCAATTCATTGGGCAACAGTAATTTGTTCTGTAGCCAAATTTTTTTAATGGGGATACACGTATTGACCTTAGCAGTTTTTAAACTAAATTTAAACAAAATTTTCTCCAGAAGGTTAAAAAAAGTTGCAAAAATTGTGAAATTTTTCTTTGCTGTTAAACTTTACTTGGGTAATATCAGCAAAAGAATTCAATCTTCACATATACTATATAGCCACATGATATAAACATTATAATCACAAATTGCACAAAAGTAGTGCAATTCTTAGCATGAATACAGTTTAACATGAATTGTTTGTGTATGTATGTAGTGCGAAACCCGTA[C/A]ACAGGTCACAAGTACCTCTGTGGAGCTTTCCAGTCCAGTGTAATGCTGTTTGAATGGGTGGAAGCCATGCAGCGCTTCATGCTCATAAAGGTAAGTGAAAGAAACTAAGAAATGACATTAAACGTCTGTAAGGCTTGAAGCTTACGCTGCTATTCTGAACCAATAATTGAAAACAGAAAGCAGTTGAAGGATGGCGTGTTTAAATCAATTACTTATTTGAATCTATTGTAATCCATTAAAGTTGTTATCATTGATAAAGAGAAAGAATCTCAACGCCTTAAAGCAGGCAGTGTTGTTTATTAAGTTAGATGTTTAAATATACAGACAGTAGAACAAAACAAACTAACATACTGGATAGAGAAACATAGCTGTAACTATGCATCAAAGTCTATAACGCTGTGTATTTGTGTCTGTCCAGAGTATAGAGCTCACCCTGCCGTGTCCATTAGAAGTGTTTGAGATGTTGGTGGTTCCTGAACAGCATTATCCTGTGGTTTGTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18499
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000093004 Essential Splice Site 794 864 31 33
Genomic Location (Zv9):
Chromosome 17 (position 24488213)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 24641655
GRCz11 17 24660056
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGTGGAATTAATYGTTTGCTTWAAATGATAATTATATATGTCCTTTTCAA[G/T]TGTGTCTGCAGGACAGTGTTTTGGCGTTCTGGAAGCATGGAATGCAGGGA
Long Flanking Sequence:
CTAGAGAGCATTTGATTGGTCATGATTTGTTGAGAAACATATGAGGTGATGTGAAAAAGCCATTAATACATTTAGGCAGAAGTGACAAACTAAAAGCCTTAGATGTTATATCACTTTTATATCTTCTAAATGCCAATTGTGTCACTGTTTTGGAGCACACTAGCGTATAAATATCCTTAAAACTAATAATACTAATAATAACATCCAAAAAACATTATTTTCATTTCATTGGACCTTTAAAGCTTTCGTTGTTTTTGAGTTCACTCAATGTCCCTGATATCCTTTATCCAGCAGCTTCCACTCACAGTGTGTTTCGGTATTTTGCAGGATGTATAAAGTTGGTAAATTTACAAGGCAGATTAAAATCCAACAAGAAGTTGTCAACGGAACTCACTTTTAACTTCCAGATTGAGGCAATAGGTAAGGATTAAACTAATGTAAAATATTGACTGTGGAATTAATCGTTTGCTTTAAATGATAATTATATATGTCCTTTTCAA[G/T]TGTGTCTGCAGGACAGTGTTTTGGCGTTCTGGAAGCATGGAATGCAGGGAAGAAGCTTTAAAAACAGTGAGGTATGTCATGTAGTTCTGTAGTTCTTAGTTTCTTAAGTAGATTTCTACTTTAAGTCTATTTTCTTCCAAACTAAATGTTTTTGCTATTGTTTTGTACAACACAGTACATTTTAATTAAAGGAAAGCAAAAATCCTATCAAAGCTACATGCTAATTCATACTGGAAACATGGTGATACACTTATTTCACATGGCCGCCATTTCAAAAAACGAAAGAGAGACTGCGGTGGGAAGAAACCCGAAGGTATAAGATCAGCACTATAAACATTGCAACAACATGCTGTGGACTACAAACCTCCAGCTGTTGCTGTCATTTCAAAGTGCAGATATGATGTAAATATCACTTTAATATCATTCAGTTAAGTTTCATTTAAACTATTTAAAGCATATTAGGTATCAAACAAACTGACAATAATATGCTTAAGTTCATA
Associated Phenotype:
Not determined