ZMP
chrna2a
Ensembl ID:
ZFIN ID:
Description:
cholinergic receptor, nicotinic, alpha polypeptide 2a [Source:RefSeq peptide;Acc:NP_001035417]
Human Orthologue:
CHRNA2
Human Description:
cholinergic receptor, nicotinic, alpha 2 (neuronal) [Source:HGNC Symbol;Acc:1956]
Mouse Orthologue:
Chrna2
Mouse Description:
cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) Gene [Source:MGI Symbol;Acc:MGI:8788
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa36297 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa28784 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa36297
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000033947 | Essential Splice Site | 91 | 520 | 3 | 6 |
Genomic Location (Zv9):
Chromosome 17 (position 5854714)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 17 | 5933650 |
| GRCz11 | 17 | 6090880 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACAGGATGAGAAGAATCAAATGATGACGACAAACGTTTGGCTGAAACAG[G/A]TGATGATCTTTATGTTTATTTCTAATGACCAATAAATTGGGCGACACGGT
Long Flanking Sequence:
ATAAAACGTAAAATAACGTCCATTAAAAAAACTGAAATTTGCTGTAAATTTACAGTACAGTAAATTTCTGTAGTTCAACCTGTTAACTTACAGTAAATTTCTGTGATTTAACGGCCGTTATTATTTGTTTTTTTCCCCTGCTGCTGGAAATAAAATGTAAAATTACAGATTTTTTTTACAGTGTGGTTTACATCTTCTAAACACAAATTTTGTCACTGTTTTGAAGCACACTAGCTTATAAATATCTTTAAAAACTAGCATACTGATACTAACATCTAAGAAATTGTATTTGACTTTTCACAGGACCTTTAAAATGCCATAAAAATATTAAAAGGTGAGAAAAGTAAATGTTTATCATTGTTTTTTGGTTGCTAGGCTTCAAACATGACTCGAATCTTTTACTTAAAGTAAATCTGTGTTTTTTTTTTTCCGCATGTTTGATGCAAACTTCACAGGATGAGAAGAATCAAATGATGACGACAAACGTTTGGCTGAAACAG[G/A]TGATGATCTTTATGTTTATTTCTAATGACCAATAAATTGGGCGACACGGTGGCTCAGTGGTTAGCACTGTCACCTCACACCTAGAAGGTTGCTGGTTCGAGTCCCGGCTGGGCCAGTTGGCATTTCTGTATGGAGTTTGCATGCTCTCCCTGTGTTGGCGTGGGTTTCCTCCAGTTTCCCCCACAGTCCAAACACATGCGCTATAGAGGAATTGGGTAAGGTAAATTGTCCGTATTGTATGTGTGTGAATTAGTGTGTATGGATGTTTCCCAGTGATGGGATGGGTTGCAGCTGGAAGGGCATCCGCTGCGTAAAACATGCTTGATAAGTTGGCGGTTCATTCCGCTGTGGAAACTCCAGATGAATAAAGGGACTAAGCTGAAAAAGTGAATGAATGTGTGAATAAGGTATTTTACTGTAGCAGTTTTCATTAATATGCACATTTACTCTACAAATATGATTCTCTGATCCTCTACAGGAGTGGAATGATTATAAACTGC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa28784
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000033947 | Nonsense | 459 | 520 | 5 | 6 |
Genomic Location (Zv9):
Chromosome 17 (position 5861572)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 17 | 5940508 |
| GRCz11 | 17 | 6097738 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGGTAACCTGGTGTCAGAGCCTGGTCTGCTGTTTTCACCGTGTGTCCTG[C/T]GAGCTCTGGAAGGGGTGCGGTACATCGCTGATCATCTGAGGGCTGAGGAT
Long Flanking Sequence:
TCACTGAGATAATCCCCTCAACATCTCTAGTCATTCCTCTAATCGGCGAGTATTTGCTGTTCACCATGATATTTGTAACGCTCTCCATTGTCATTACCGTTTTTGTGCTCAACGTGCACCATCGTTCACCTAGCACGCATTCAATGCCACGTTGGGTTCATTCGGTGTTCCTGGACCACATTCCCCGCTGGCTCTTCATGAGACGTCCAGAGCCTGAAAAGAAACCAAAAAAGACAGCCAATCTGAGCACATCCAAGAGCTGGTTCCAGCAGGAGACTGGAGTGGATGGTCTGGTTTGTCAGGATATGGAGTTTGGGATTGGTTTATCCACATCCATCTCCTCTCCATCCGCAACCTCTCTGCATTTGTCTGACTCAGAGCCTTTACTCCAGAAGTATGAGCTCCAGCATTTGGGACATGTGGTGAATCTTTGTCAGCATCCTGCTAAGCTTGGTAACCTGGTGTCAGAGCCTGGTCTGCTGTTTTCACCGTGTGTCCTG[C/T]GAGCTCTGGAAGGGGTGCGGTACATCGCTGATCATCTGAGGGCTGAGGATGAAGACTTTTCAGTGAGCAACGCAATCACACTGGTTTAGTCATACAAGCTCATCTATACCACAATTATAACCATTATTTCCTAAAGGGGACCTATTATGCGAAAGTCACTTTTATAAGGGGATTATGTGGGAACAGCGTGTGATTATAGCCAGCTTCTAATGGTCTCAATTAATTAATTACATTCTTTATAATCACGCTTGCTATAGTGTGCAGAAACACTTTGATTGACATTCTCCCTTTGGACGTGTCATCAGAGGGGAAAAGCCCCGCCCATTAGTGACCATCTCTCCCTCATTGGCAGAGGACGTCAGTTTTGTTTTTGAATCTGCTACTACCCTGCTGAAAAAATTCAGCTTACACCAGCCTAGGCTGGTTGGCTGGTTTTAGCTGGTCAACCAGTCTGGTTTTAAAGGGGTTTTGGCCATTTCCAGGCTGGTTTGCAGCCATTT
Associated Phenotype:
Not determined