Busch Lab

ZMP

ide

Ensembl ID:
ENSDARG00000075570
ZFIN ID:
ZDB-GENE-070410-85
Description:
insulin-degrading enzyme [Source:RefSeq peptide;Acc:NP_001082994]
Human Orthologue:
IDE
Human Description:
insulin-degrading enzyme [Source:HGNC Symbol;Acc:5381]
Mouse Orthologue:
Ide
Mouse Description:
insulin degrading enzyme Gene [Source:MGI Symbol;Acc:MGI:96412]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa42283 Nonsense Mutation detected in F1 DNA Not yet available
sa35572 Essential Splice Site Available for shipment Available now
sa28188 Nonsense Mutation detected in F1 DNA Not yet available
sa15036 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa42283
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000113215 Nonsense 43 998 2 25
Genomic Location (Zv9):
Chromosome 13 (position 42965062)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 42186021
GRCz11 13 42312081
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGAGGGTGGTGAGTGATATCATTCGCTCTCCAGAAGACAAACGGGAGTA[T/G]CGAGGACTCGAGTTTACAAATGGTCTGAAAGCCATTCTCATCAGTGACCC
Long Flanking Sequence:
TATGCACATATTACTGGTTTTGTGGATAATGGTCACTAATGAAATTTTGAGTTTCTAAAATAACAATAGACAATAAAATAAACACACTTTGGTTTCTGATGATGCACTGAGGACGGTCTAACGTTGCAGTCTTAAGTGTCTGGAATTTTGTGTTTTAGACTGTCACGAACATGCTCAAGACTATTTAAAGCGGTTGTTAATTAAACATAATTGTTTTTTTTTCATCAAACTTTTTATTGTCAGGACTGGAGCCATGTGTATTAATTTTTAGTTAGCCTGTATATTGTTTTTGTTACTTTCAAAGTGACTGTAGCATCTGTCTTGCATTTTAAAAATCACCATTTACTAGAGTTTGTTTGATAGTAGCTGACCTGAATGAATTCTGAATGAATCTTTTGTTTGTCCAGACGTGTGTCGACTCTGTCCATCAGAATGAGTGATCCGGCTGTCAAGAGGGTGGTGAGTGATATCATTCGCTCTCCAGAAGACAAACGGGAGTA[T/G]CGAGGACTCGAGTTTACAAATGGTCTGAAAGCCATTCTCATCAGTGACCCCACCACTGACAAATCATCAGCTGCCCTGGACGTCCACATGGGTAAACCGGAATAGTCCATCTGTTGTAGACCTATGTCGATATTCAATATTAATTATATTCAAATATAAGTTTATTTGTATAGCACTTTTCACAATAATTATTGTTTCAAAAAAGCTTTATGAAATGTGCATGTTATTGCATTACAGTCAAAATCAGAAAAGTTAAGATTATTAGTTTCATAATTTTAGTATTTACTAATAACTTTAACTAGTAACTAATAGCTTTCAACAGTTAATGTTATTATAAATAAACATGGTTGACCTGCAGAAGTATAGTATAAAAGTGACGTTTATGTCTACATGTTTAATGAAGTGTATTTGTGCATGTCTATTATGTTGCTCAATGTTGATATTATGGCCACTTCAAAATACAGTGAATAGTTATTGAATATTTAATCTTTTAGAGTGCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35572
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000113215 Essential Splice Site 490 998 12 25
Genomic Location (Zv9):
Chromosome 13 (position 42982210)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 42203169
GRCz11 13 42329229
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTACGGCACACAGTATAAACAAGAAGCCATTACTGATGAAGCTATTAAGG[T/C]GAAGCGCGTTTGATTTTAGCAAATCTCTCTCTCTAGTATGTCATGGTACA
Long Flanking Sequence:
GTGATGTGGTCTAAATCTGGAAGGAGTGATCTGGATTTTAAAGTGAACCTATTCTGGGCTCTCTTATGCAATTGATTAATTGCAGGAGAGTCCAGAATAGCACGTCATTGTCCCAAAAGTTCTCTATTGATCAGTAGAGTCTAAATTGTGCAGAAATAGTGCATTGATCCACAGCCCCGCACAGCAGATTGAGCAGCTTCGGGAAACTTGAACCTTTGATGTAATGACCATAATTCCAAATCTATTTACTGGGCCAGAGAGATCTGATAAAGGCAAAATTGCACAGCCCATTTTTTCCCCCAAGGGACTTGTGAGAAATGGATGGTGTCATGCTGTGTCTGGTGAATTGATCTTTACAATTCTTTTCTTTTTTTCCCCCTCACTCACTTCTTTTAGGGTTGCAGTTGTCTCCAAATCATTTGAAGGACAGACTGATCGGACTGAGGAGTGGTACGGCACACAGTATAAACAAGAAGCCATTACTGATGAAGCTATTAAGG[T/C]GAAGCGCGTTTGATTTTAGCAAATCTCTCTCTCTAGTATGTCATGGTACATAAACCTTATCTTTGACATTTGTCGTTGTGTAGATCACGGGTATCAAACTCAGTTCCTGGAGGGCAGCTCTGCACAGTTTAGTTCCAACCCTAATTGAACACGCCTGATCAAGCTAATTGAGTCCTTCAGGCTTGTTTGATACCTACAGGTAGGCGAGTTGAAGTGCAACTAAACTCTGGAACTAAACTCTGCGGCCCTCTATGAACTGAGTTTAACAGCCCTGGTGTATTTATATATTTATAGAGAAGAGAAACATATAGTTGTGACGAAAGAATATTTTTATTTCAAAAACATGTTAATAGAACAGGGGTGGGCAATCTCGGTCCTGCAGGACCGGTGTCCTGCACAGTTTAGCTCCAACCCTAATCAAACACACCTGCTTATAGATTTCTTGTGATCTTAAAGACACTGATTAGCATGTTCAGGTGTGTTAGACTAGTGTTGGAACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa28188
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000113215 Nonsense 774 998 20 25
ENSDART00000113215 Nonsense 774 998 20 25
Genomic Location (Zv9):
Chromosome 13 (position 42994103)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 42215062
GRCz11 13 42341122
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TACCAGCAGAGGAACGAGGTTCATAATAACTGTGGGATCGAGATTTACTA[T/G]CAGACTGACATGCAGAACACCCATGAGAACATGCTGCTGGAGCTCTTCTG
Long Flanking Sequence:
GCATGCTCACACTAAACCCCTTCTACCGAGTCAGCTGATTCGCTACAGAGAGGTGCAGGTTCCTGATGGTAAGTGCCTGACACCATAAATGTTTATGCAGTTTTTCATTTTTCAACTTAAGTTTCTTATGTGTGAGATTGGTAAGATTTTTGGAAAAGGGTCTGCTCACCAGGGCTGCATTTATTTGATCAAAACACAAATGCTATTTTATTTAAGAATTTTAGATTTTTATTTTATTTGTTTATATTTTTATGGGAAGGCATTTAACACTATGTAAGCTCCTTTTGGACATTTCACAAGACATTTTTATTAAATTGAGGAACTTGAGGAAAATGAGACTGGTGTTAAACCTAAATCACTGTTGTGTAATTTTGGGTGATTGTTGTGTGTTTGTCATGGTTCTTGTGTTTTAAGTCCAGTTCTCTGTGGTTATCAGGTGGTTGGTATGTATACCAGCAGAGGAACGAGGTTCATAATAACTGTGGGATCGAGATTTACTA[T/G]CAGACTGACATGCAGAACACCCATGAGAACATGCTGCTGGAGCTCTTCTGTCAGATCATCTCTGAGCCATGCTTCAACACGCTACGCACCAAAGAACAGCTGGGTAAATCAAAACTGTCATGAGCCAATGTTTCATTTGTGTGTGTGTGTGTTCGCTAAAACTATATGGTTTTTGTTTGTCAGTAATATAATTGGACCAGTGGAGAAAAAAAACAAATCATTACTGTTTATTTTAAGGACAAAATATAAATTTAACATTACGGTATGCAATGTATAAATGCATTTATGAGTTATTAATTTTTATTATATCTTTATATTTACTAATAAACAGTTATTTTCAAAGATACCATTCTTTAAAGATGACATCTCAGCTGGCAAAGTGTTTCTCAAACAATGTGTGTAATCCAGTTAATATGCATGCAAATGCAGATTTTCTTCTATCGATTTACATGAACACACACCTGCACATGTGGAAGCAAAAACAGCCACACACAGTCTAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15036
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000113215 Nonsense 774 998 20 25
ENSDART00000113215 Nonsense 774 998 20 25
Genomic Location (Zv9):
Chromosome 13 (position 42994103)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 42215062
GRCz11 13 42341122
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TACCAGCAGAGRAACGAGGTTCATAATAACTGTGGGATCGAGATTTACTA[T/A]CAGACTGACATGCAGAACACCCATGAGAACATGCTGCTGGAGCTCTTCTG
Long Flanking Sequence:
GCATGCTCACACTAAACCCCTTCTACCGAGTCAGCTGATTCGCTACAGAGAGGTGCAGGTTCCTGATGGTAAGTGCCTGACACCATAAATGTTTATGCAGTTTTTCATTTTTCAACTTAAGTTTCTTATGTGTGAGATTGGTAAGATTTTTGGAAAAGGGTCTGCTCACCAGGGCTGCATTTATTTGATCAAAACACAAATGCTATTTTATTTAAGAATTTTAGATTTTTATTTTATTTGTTTATATTTTTATGGGAAGGCATTTAACACTATGTAAGCTCCTTTTGGACATTTCACAAGACATTTTTATTAAATTGAGGAACTTGAGGAAAATGAGACTGGTGTTAAACCTAAATCACTGTTGTGTAATTTTGGGTGATTGTTGTGTGTTTGTCATGGTTCTTGTGTTTTAAGTCCAGTTCTCTGTGGTTATCAGGTGGTTGGTATGTATACCAGCAGAGGAACGAGGTTCATAATAACTGTGGGATCGAGATTTACTA[T/A]CAGACTGACATGCAGAACACCCATGAGAACATGCTGCTGGAGCTCTTCTGTCAGATCATCTCTGAGCCATGCTTCAACACGCTACGCACCAAAGAACAGCTGGGTAAATCAAAACTGTCATGAGCCAATGTTTCATTTGTGTGTGTGTGTGTTCGCTAAAACTATATGGTTTTTGTTTGTCAGTAATATAATTGGACCAGTGGAGAAAAAAAACAAATCATTACTGTTTATTTTAAGGACAAAATATAAATTTAACATTACGGTATGCAATGTATAAATGCATTTATGAGTTATTAATTTTTATTATATCTTTATATTTACTAATAAACAGTTATTTTCAAAGATACCATTCTTTAAAGATGACATCTCAGCTGGCAAAGTGTTTCTCAAACAATGTGTGTAATCCAGTTAATATGCATGCAAATGCAGATTTTCTTCTATCGATTTACATGAACACACACCTGCACATGTGGAAGCAAAAACAGCCACACACAGTCTAA
Associated Phenotype:
Not determined