ZMP

eef2k

Ensembl ID:

ENSDARG00000035835

ZFIN ID:

ZDB-GENE-020916-2

Description:

eukaroytic elongation factor 2 kinase [Source:RefSeq peptide;Acc:NP_001002740]

Human Orthologue:

EEF2K

Human Description:

eukaryotic elongation factor-2 kinase [Source:HGNC Symbol;Acc:24615]

Mouse Orthologue:

Eef2k

Mouse Description:

eukaryotic elongation factor-2 kinase Gene [Source:MGI Symbol;Acc:MGI:1195261]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa35222	Essential Splice Site	Available for shipment	Available now
sa41972	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa35222

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

A > T

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000052001	None	None	706	None	17
ENSDART00000122437	Essential Splice Site	481	744	13	18

Genomic Location (Zv9):

Chromosome 12 (position 11470686)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	12	10353757
GRCz11	12	10391600

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TCCTTGTTGGCTCCTGAGATATGTGATGGTAGGTTTTTACATCATTATTT[A/T]GGGGCGTCCCATCTACAACAGACATTACTCAGAATCGGATGAGGACAGTG

Long Flanking Sequence:

CCCAGGACAGCATGCCAAACCTGCTATTAGCATCAAGCAACTCTTGAATTAAAAGCCAAGATAGTTTAGCCTATCTTGCATTTTTGTTGGTATTTTTACCACAAAATTATTATTATTTTCAACCCAGATCTACTGTTTGCAAAGCTAACTGATTAAAAGGTTAAAAATGTACTTCACAGGACTCTGAAAATGGAGGAGACAGTGGTTACCCAAGTGAGAAACGCAGTGAAGGAGACCCAGTCGAACATCATGGTCAGGTACAACAAAATTCATTCTATTATTGAATTGAGTAACTATTGTTTTGTCATTTCTGAAATATGCTATGGAAAAAATGCAGTAATGCTTGCTTGTTTTGGTTGTTACTCTGCAACAAAGTTTCCCTTCGATTGCATTATAAATGTCCTGTTGTTGTGTGCTGTGCTAAAATATAACGTGAAATGACGCAGTAAATCCTTGTTGGCTCCTGAGATATGTGATGGTAGGTTTTTACATCATTATTT[A/T]GGGGCGTCCCATCTACAACAGACATTACTCAGAATCGGATGAGGACAGTGTTCGGCGGGTAACTACAATACCATTGATAAACTCACTTCATCTAATCATCATAGAATCACCCATTGATTCCTAATCCCTCTCATAGAACATAGATGTAGAGTGGTGTCTTCTTGTGATCCACCTTTTATCTAAACCTCTAAACCTTCTCAGCTTTCATCTTCTTTCATCCAAACTCTCCCCTATTTACCTCATGTCACTTTTATCCGATCATCAGTGGCTAGCTTTGCTTTCTTAACTTTAATCCCATATGCAGGGTTCCCTTGCTCATGGTAAACCTTTCAATGTCAGGGAATTTTAAAGCTGAGATTCTTAATGGCACGAACATTTCATTGACTTGCATTTGTTGCTTGTGAGTGATTTTTCTAAAGTATTAGATATAGTAAACCCGAGTAATAACTAATAAGTTGATTTTAGTCAATATTTATGTTGGAACCCTGCTTGTGATTTCT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa41972

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000052001	Nonsense	615	706	16	17
ENSDART00000122437	Nonsense	653	744	17	18

Genomic Location (Zv9):

Chromosome 12 (position 11464100)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	12	10347171
GRCz11	12	10385014

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TTTCATATGAGACCCCTCAAACCTGAATTTGAATCACAGGGCTATGGACT[G/A]GACAGAAGCTGTGCACTGGTATGACTCCGCCCTAAAGATGACAGACTATG

Long Flanking Sequence:

CCCTCTACGCCACTGAACATGTGTACTGAGCTGCCAGCCCAGTGCTCTGTCTCTAGTGTATCTGGCCTCTGTTATTGCTCTGTTTACACACATTGTACTTTAAGATGATTGTAGTGTAGTTTAGTGTAGTTTCATGTCATTCCAGAACTAAAATGGAAGAAAATTAAATAAAGAAAGAAGTTTCTGATTTTGGTGTGCATCGATAACAAGGATTTTATGCAAGATGTAATTTTTTATTTGAATTTGCAGATCTTAATAAGCATAAAAGGCTGTTATGAAAGCAAAAATGTCTTTGTATGGTTTTGGTTTTGTGAAATTTAATATAGAAATGTGATTTAATATAGATAGTGTAAGTAATGTGGCCCTGCTAACAAATCATTTCATTGGTAAATTTATATAATAACAAGTATTTTGTCATATAGTATATCATAACATTATTCCAAAAATATCTTTCATATGAGACCCCTCAAACCTGAATTTGAATCACAGGGCTATGGACT[G/A]GACAGAAGCTGTGCACTGGTATGACTCCGCCCTAAAGATGACAGACTATGACGAGGGTGGAGAGTTTGACGGGATGCAGGATGAGCCACGATACCTTCTGCTGGCACGTCTGGCTGAGATGTACCAGGAGGGTGGAAACAACCTGGATGCAGACCCTCAAAGAGCAGGTGAGCGAATCTCAGGCTGCAGTCATGAACACAGTGACAGTGGTTCTGCTGCAGAAAATCAGAGGTACAATTCCATATAATCATTCGACAGATGATGTTACCCAGCTCGTCTTCCAAATGATGATAAAACAAATAATCAAAGAAACCAAAAAACAATGTAAATTTTGAATTTTATATTTATTTATTTTTTAAATAGACATTATCATTAATTTTTTTCTTCTTCAGCTTAGTCATTTATTTATCACGGGTCGCCACAGCGGAATGAACCGCCAACTATTCCATCATATGTATCACGCAGCGAATGCCCTTCCAGCCACAACCCAGTATTGGGAA

Associated Phenotype:

Not determined