ZMP

pfkfb4

Ensembl ID:

ENSDARG00000055540

ZFIN ID:

ZDB-GENE-051120-51

Description:

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [Source:RefSeq peptide;Acc:NP_001032454]

Human Orthologue:

PFKFB4

Human Description:

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [Source:HGNC Symbol;Acc:8875]

Mouse Orthologue:

Pfkfb4

Mouse Description:

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 Gene [Source:MGI Symbol;Acc:MGI:2687284]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa27816	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa35129	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa27815	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa27816

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > G

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000077883	Essential Splice Site	46	482	1	14
ENSDART00000133302	None	None	453	None	14

Genomic Location (Zv9):

Chromosome 11 (position 35409549)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	11	34309923
GRCz11	11	34572022

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CCATCCTCCAGAAACGGCCTTCCTGACAGGCACATTAGTCAGAAAAAGGG[T/G]AAGCATGAATGAAAGGATGAGATGCTGGAGGCAGATTTGGGTTAAAGGGG

Long Flanking Sequence:

ACGCAACAGATGTCAGATGACTACACAGCGTTCTTCACCATTACGTCTGGTGAACAGAACAATAACACATATAAACTTTAGTAACAACTAATCTAAAAATGGTACAAAGATCAGTTTTAATAATGCTACATTTCAGGCTTTTAATATAAACCAAGCGGCCAAACCATGTATCTAAAGAAATCTTTTTTTAATGTATCCTACTGTTGAAAACACACCAATGTTTACGGTAAATATGTGTAAGCGCGCATCCGCTCCTGTCATTACGGTAGACCTTTTCCCTACCAGTCTCATGCCGTTCTTCAACGCTGTCTTTAGTGCGCACTGATGGTTATGGACGCTCGAGTGTAGAGACGACGGAATATAATGAGTTTAATAGAGAACAACACGGAGCAATGCGGCAATAGTCTGACCCGAGAGCTCACCCAGAATCCTTTAAAGAAAATATGGGTGCCATCCTCCAGAAACGGCCTTCCTGACAGGCACATTAGTCAGAAAAAGGG[T/G]AAGCATGAATGAAAGGATGAGATGCTGGAGGCAGATTTGGGTTAAAGGGGTTTTTCTGATGCAATACTCATAATATGACAGACTATTTAACCCTATATTTAGAGCTGAACATGAAGAAATCGAGAGGATTTTGTTTGAGTACGTTTACTTTTTTAAATAATTATTTTTAATAGCATTACATAAGATTTAAGAAGATTACGAGTTGTGTTTTACTGTATTATTGTATTATATATGTGATGTATAACGTTCATTTGTTACAATTTAAATTGTTGCACAGTACTTGGCTAGCTTGTAATCTTAGATATGTAAACAAATGAACTAAATAAGAGATAATAAATCGTAAATAGTTGTAAATTAAATAGTACATTATTACAGTATTGTGTAATAATGCTGTATTGCTTTAGTAATAGCACATTTGTTACATATTATTAAATAAATTACTACTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa35129

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000077883	Essential Splice Site	85	482	2	14
ENSDART00000133302	Essential Splice Site	56	453	2	14

Genomic Location (Zv9):

Chromosome 11 (position 35407055)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	11	34307429
GRCz11	11	34569528

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TCCAAAAAACTGACACGCTACCTCAACTGGATTGATGTTCCTACGAAAGG[T/C]TTGGATTGAGTTTACAAAGAGCAGATTTGTGAAATGCCAGGCCAAGATTG

Long Flanking Sequence:

GTGATTGTACCTCTACCTTATCATTTATGTCTCAAATGGAAATATTTGTGATTGTTTTTTGAAATCCGGTACATAATTTTAAAATGTACAAACCAATAGCAATATAACATGTTCACCCATGTTTTTATTACACAACTGTATAGACATAGATATGATATTATGCTCTTTGATGTGGCAATATCAAAGCGACTTCTGCTCTACAATGACAACTCACAGATTTGATTAAAGCAATAAAAATGCCACCAGAACTGCACAAAGATCAAATCATTCCTGTTCTTTATGCAATAAGGTGTGTGATGATCGACAGCTCGGCTTATATGCAAAGCAGGAGCTAAACGTGTTTTTCAAGTGTTTTATGAGACGCTGTTTTTGTTTCTTCCAGTATGCATGACAAACTGCCCTACGCTTATAGTAACCGTCGGTCTGCCCGCCAGAGGAAAGACCTACATCTCCAAAAAACTGACACGCTACCTCAACTGGATTGATGTTCCTACGAAAGG[T/C]TTGGATTGAGTTTACAAAGAGCAGATTTGTGAAATGCCAGGCCAAGATTGTGTTAATCCACATGTGGTTTTGCTCTTCCTCAAGTTGGTTTCCTTTTCACTTCCGCAGAGTTTAACGTTGGCCAATACAGACGAGAATGTGTTAAGATCTACAAATCCTTTGAGTTTTTTCGACCAGACAATGAAGAGGGGCTCAAAATCAGGAAGTAAGACTAAGATTTTTGTCAATATAAACAAGCTACTGTTATTCTGCAAATGTTCATAAATTCTTTGAGAACATAATCCCCATTGAGTTTACTTTCTCAACATTATGTTTATCAGGGTGTCTTAAAAAGTATTACATTTCAATTCTAAAATTTTAGACCTAAAAAGTCTTGTAGTCTTATATGTCTTAAATAATTTTAAATGGGTCTTATTTTTCCCATGTCCATGTAAAATTAATTATATTTAGTTTATTATCATTTTTAAAACCTCTTTTAAAGAAAATCTAGATTGAAGATA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa27815

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > G

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000077883	Essential Splice Site	184	482	7	14
ENSDART00000133302	Essential Splice Site	155	453	7	14

Genomic Location (Zv9):

Chromosome 11 (position 35403745)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	11	34304119
GRCz11	11	34566218

KASP Assay ID:

554-6693.1 (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TAATATCTTTATCTCACTGTATTTTGTATAAATTTGTGCTTTTTGTGTGC[A/G]GCAAGTGAAGCTGGGCAGTCCAGACTACACACACTGTAACACAGAAGAGG

Long Flanking Sequence:

AGCTTCTGAAAAGACAAAAAATGCTTGTCAAAATAAGAAAACACACTGTATGTTTTGCTCGCTTAATATTAGGAAGTCATTTTGAAATATTGCATTATGTTTCAGATGATAAAACAGCAACTTTCATATTCCAGAAAATACAGTAGTTGCGATTTAAACATTTTATTTTACGCATTTATCTTGTTTTTTATTACTCAATCCTCAGGTTTTTGATGCCACAAACACGACAAGAGAAAGAAGAGACACAATCATCAGATTTGCAGAGCAGAACGGTTTCAAGGTGCTTACTATGAGATTTTTCATCTAAAGCTTGTATTTTCATGTGTTTCTCATTTCAGCTCTTTTATAACGCTGTTTTCCTCTCATCTTTAAGGTGTTCTTTGTAGAGTCTGTGTGTGAAGACCCTGACGTTATCGCTGAAAACATTGTGGTAAGTCACAGAGACGTCTTTAATATCTTTATCTCACTGTATTTTGTATAAATTTGTGCTTTTTGTGTGC[A/G]GCAAGTGAAGCTGGGCAGTCCAGACTACACACACTGTAACACAGAAGAGGCCGTCGCTGACTTTATGAAGAGGATAAAGTGTTATGAGAACTCCTACCAACCCCTGGATGAGGAACTGGACCGGTATATATCATTTAAAGTGCTGTTGAGCTGAATCTTGAATTTTATGAATAAATGTAATCTTTTTTCTGTTTGTGTGTGTTTAGGGATCTTTCCTTCATAAAGATCATTGATGTGGGCCGAAGGTACCTAGTGAACCGGGTTCAGGACCACATACAGAGCAGAATAGTTTACTACCTCATGAATATCCACATCACGCCGCGGTCCATCTACTTGTGCCGGCATGGAGAGAGTGATCTGAACATTAAAGGCCGAATCGGAGGAGATTCAGGGCTTTCAGCAAGGGGAAAGAAGGTAAGCTGTTTAGGCTTGTTTATGTTAAGTCATCTTTTTTAGCCTAGCATTTATTCACAAAAATGCCAGGAGGTTTGATGTCTTGA

Associated Phenotype:

Not determined