Busch Lab

ZMP

LOC561737

Ensembl ID:
ENSDARG00000075456
Human Orthologue:
PIK3CA
Human Description:
phosphoinositide-3-kinase, catalytic, alpha polypeptide [Source:HGNC Symbol;Acc:8975]
Mouse Orthologue:
Pik3ca
Mouse Description:
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide Gene [Source:MGI Symbol;Acc:MGI:1206581]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa16936 Nonsense Available for shipment Available now
sa35128 Nonsense Mutation detected in F1 DNA Not yet available
sa35127 Nonsense Mutation detected in F1 DNA Not yet available
sa35126 Nonsense Mutation detected in F1 DNA Not yet available
sa45434 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa16936
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114004 Nonsense 261 1071 3 19
Genomic Location (Zv9):
Chromosome 11 (position 35345902)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 34246276
GRCz11 11 34508375
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CAGGAATATMAGGGCAAATACATCCTGAAGGTCTGCGGCTGTGAMGAGTA[T/A]CTTTTGGAAAAGTACCCCATCAGTCAGTACAAGGTACGTTTAGGCCCTTT
Long Flanking Sequence:
GTGAATGGGCCTGTGTTGTAATAGTAGTAGTCGTCACGAAGCATATGATGTTTGTTTTGATGCTTTTGCCCACTGTCTCCTCTTAACCCAGAGGAACGCAAGCACAACAACTCTATTACATTCACTCCCTGACAGCTTCATTCGGCTGCGTTCAATATCCAGGGCTTTTTTTAACACACTCAGTTGCCATGTGGGATTAATTGTCTGTTCTCACATGCTTGATGCCTGAAGGAGTCGATCCAATAGAGCCGATTGTGTTAACACTTCTCCTTTGTTGTGCTAGGTCAAATCATTGTGGTCATCTGGGTGATCGTCTCGCCCAACAACGACAAGCAGAAGTACACACTAAAGATCAATCACGACTGCGTACCTGAGCAGGTGATCGCCGAAGCCATCAGGAAGAAAACCAGAAGCATGCTGCTGTCAGCCGAGCAGCTAAAGATGTGCGTGCAGGAATATCAGGGCAAATACATCCTGAAGGTCTGCGGCTGTGACGAGTA[T/A]CTTTTGGAAAAGTACCCCATCAGTCAGTACAAGGTACGTTTAGGCCCTTTTTATCATCACTAAAGTGCCAGGTTTTGTTCTGTTCATTCTGATTATAGGTTACTCCAGGTCAAAGTGGCATTGTTGAGAGTAAACAAACTCAAAAAGGTTATATGATTTAGTTCAGTACTAAAAATAGGCTACCAGTAGGCCTAATTAAAAAAAGTTTAAAAGGTTATAGTTCTTATAACTACCTTGTGTTTTGATTATTATTTATTGTATTGTTTTATTTAGTCTTTTTATTTTACCAGTAAAACCTTGAGATTGTAATCTCTTTTTCAAGAGTATTTTGGACGAACAAATAATAATAAACTTTACAATATAACAATGCAAAATACCCTTAAATAAAACGAAATGTACCACCAAAACTTATCCAATAGATACAGTAGTAAAAGTAAATCATAAGATTATGTAATGGTTTAAGATAAATATGAATTATCCTACAATTAACAGAGCAAGTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35128
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114004 Nonsense 408 1071 6 19
Genomic Location (Zv9):
Chromosome 11 (position 35340226)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 34240600
GRCz11 11 34502699
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATGTACATTCCTGACATCCCCCGGGCGGCTCGTCTCTGTCTCTCCATCTG[T/A]TCTGTGAAAGGAAGGAAGGGGGCAAAAGAGGTGATAACGCTTTTCTGTCG
Long Flanking Sequence:
TTCTGTGGCAAAAAATGAGCTTCCGTTTGTCTTTTGTAATGGAGTAAAATCATGCAGATGTGTTAAATGTCAGAGGAGGCACTTTATCTTATGCAACCTTTTTGACATGAAATGCCATTTTTCTTGTTTATCGTCGTGACATAAACACATCACCCTTTTTTTTCTGTAGAAAATATCATTTCAAAATTTCTCCCTTATTTACGCAAACATTTTGTCACTTCTAAGGTCAATGTGTCACAGAAGTAAATAGATTGACTTCAGTCTTGAAGCCACATGACAATTAGGCAGTTGGTTTATTCTCTTGTTTTCTAGCGATTGCTTCTCAGTCCGTCAATAATTTTATCATTTGATTGTTGCACTGCTTTTTGTTTTTTAAAAGTGTAGATGTTTTAAATGGAACATTATGTGCTGATATGTGTCTTCAGGTGGAACGAGTGGCTGACTTATGACATGTACATTCCTGACATCCCCCGGGCGGCTCGTCTCTGTCTCTCCATCTG[T/A]TCTGTGAAAGGAAGGAAGGGGGCAAAAGAGGTGATAACGCTTTTCTGTCGTGCATTTATACAGACGTCTTATAAAACCTTGCTGGTTGTGCATCCTCATGAATGTCTTTTCTGATTAATATGGCTGTGTTAATGCGAACAACAGCCCAACATTTGGCAGAGGGCTGTGCTTTATTGAAATTTTATTTCATTTCCTTTCAAAAATAGCAACACTTAGGACCTTCAGAAAAAAATGAAACCCATTAAAACAGCAATGTTTCATCATGGTGCACTCTAAGCTAAAAGTCATACATTCATTGTAAACATGATGTGATTGGATGAATACTTTTTCATGCTAGGCCTGAGGAGGGAAGCAAGAGAGGTTTTCTGCTTTTTAGCTCTCTTGGCTAAAATAATAATTTAAATTATTTAATTTTGAGTAGATTGATGTGAATATCAGAGTTTGTTTTGCATGTACTTTATACTTACACATTTGAATGCGAGCAAATTTCATTATTTTCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35127
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114004 Nonsense 514 1071 8 19
Genomic Location (Zv9):
Chromosome 11 (position 35338116)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 34238490
GRCz11 11 34500589
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTAACTGGATAATATCCAGAGAGATGGGATACAATTACTGCCAGTCTGGA[C/T]AGGTGAGCTTACAGACACACATCCTACTTAATTAATTATAGCGACACACT
Long Flanking Sequence:
TGGCCTGTACCACACGGCCTAGAAGACCTGCTTAACCCCATCGGTGTCACAGGCTCCAACCCTAACAAGGTTTCTTCTCTTACATAATCTCTTTTCAGCACTGAGCCACTTTAATAAGCTTTAATACGATTTCTCTGTGTTGTCTAATCTGAGGTGACATAGTTAATGAAGAGCATCGGTTTCAAAGCTCTTTATTTAGTATGCAGTCTTTTGTTTATTTTCGTTATCAGATGAAATTGTACATTTTTAGGACAAAACGTTATTGTAATAACCAAAACTGAAGTTGCATGGATGCTAAATATACATTAGTTTTTAATAAAATGTTGTTTGGTTACTTTTATTGTGTGTAAATGCTGTTTTTGCTTTAGGAAACCCCATGTTTAGAGCTGGAGTTTGACTATTTCAGCTCACCTGTTAAGTTCCCTGACATGGCTACAATTGAGGATCACGCTAACTGGATAATATCCAGAGAGATGGGATACAATTACTGCCAGTCTGGA[C/T]AGGTGAGCTTACAGACACACATCCTACTTAATTAATTATAGCGACACACTTCTCGATGCTATTAATACTCTTTACAAGCCTGAGCAGCATCAGAAACATCTCTGCTATTGTCTGCAGTCACCTCGGGAGTTTCACATTGCTTACAGTTTATGAAAAGCACAATGCTCGCTCTTTTATTTGATTTTATCTTAGATATTAGTTGTGACCAGACATTAGATGCCTGTTCACTCTCATAACATTGTTGCTGATTCATCTAAGAGCCTTTGAAGTATATCAGTGCCTGTTAAAATGACTTCTGTGGAAGGAAACACATTTTTACATCATCAGAGGTTTAGGAAAGATTATTACTCAATGTTAAAATATTTAAACTGCGATTGAAGTTTGTTTACTTTAAAAGTACACTGTTAGTCAAGAGAATGATTGATTCACATCTCTTAATGTTTTAGTGTACCGCCCATGGTACACTGAGTGCTTAGTTACAGCAATACAGGAATGAAAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35126
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114004 Nonsense 722 1071 12 19
Genomic Location (Zv9):
Chromosome 11 (position 35333736)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 34234110
GRCz11 11 34496209
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GACAAGTGGAGGCCATGGAGAAGCTCATCAACCTCACAGACATTCTCAAA[C/T]AGGAGAAGAAGGATGAAACTCAGAAGGTAAACTCAGCACTCGACCTTCTG
Long Flanking Sequence:
TTTAGATGCTTTAAATTAAAGTGTATACATGGTGTATACAGAATTCTAAGACAGAGAGGTTAACAGATAAAAAAAATCTTGAACTTTTTTTATATGTCCCAAAATGAACTATTCATTATTTCATTCTAGGTTTTGAAGTACGAGCAGTATCTTGATAACCCACTGGTGCGATTTCTGCTAAAAAAAGCTCTCACCAACCAGAGGATTGGGCACTTCTTCTTTTGGCATTTGAAGTACGTCATTTACTTGTTTTTCTTTCTCATTCTCATTTCCTTTTTCCACTCACTGTCCTAGATATCATGGTGTTTTTGAAGATATAAATGAAGTTAAATTGTAACTTCCCATGGGGTTGCAGGTCAGAGATGCACAATAAAACTGTGAGTCAGCGGTTTGGCCTACTGCTGGAGTCGTACTGCCGCGCGTGTGGCATGTACCTGAAGCACCTGAGCAGACAAGTGGAGGCCATGGAGAAGCTCATCAACCTCACAGACATTCTCAAA[C/T]AGGAGAAGAAGGATGAAACTCAGAAGGTAAACTCAGCACTCGACCTTCTGCTAAAAGCCGGCTCGTGAGGTTATATAAGAAGAGTCTCGGCGTATACTGCAAGTGAAACCCTAGCTGTTAGATTAGGTTGACGTGGGATACCTCAGCTACTGTGTAATACAGGCTTTACTTCAATCATCCCATTCACAGGGTGTCCGCAGGGTCTTAAAAAGTCTTCAAATGTCTTAAATTTAAAAAACAAAATTTTAGGACTTAAAAGGTCTTAAATTTAAAATAAAAAATGAAATAAAATATAAAATAAAATATAAAGTATAAAATAAAAAAAAAGTATGTAAACAACTAAGTTTGGCTTGTTTTGACACATTATTAAAAATATGTGGCTAAGAAATGACTACTTAATTTTTCTGCTGGGCCATTAAAAAAATCCTTCATGTTCAGCCCTATAGAAGTCACACATTTATATGAGTAAGTAAATGGTTTCTGAAATAAGTCTAAAATTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa45434
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114004 Nonsense 892 1071 17 19
Genomic Location (Zv9):
Chromosome 11 (position 35330035)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 34230409
GRCz11 11 34492508
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TAAAAACAAAGGAAGGTGTTTGGAGTAACCAGTCGAAATGTTTATAGGTA[C/A]GACATGGCTATAGACTTGTTTACGCGATCCTGTGCTGGCTATTGTGTGGC
Long Flanking Sequence:
CATCCATCCATCCATCCATCCATCCATCCATCCATATATTTTTTTTTTTTTTCTATTTATTTATTTTATTTTATTTTTTTAAGGGGTGAGGTCTCCCTACTTTTCTGTCCTCAGCTGATTACAAGCCTCTTTATTGTGCTGCTCTAAAACCTTTAAACGTGTAAAGCATCAGGTATTGATTTTACATTGTTCTAATTCTCCTGCTGCCACGTGTTAAGTGAGATTGTAATTTTTTTTGCTCTCCCAGAATGCTCCCCTATGGCTGCTTGTCTATTGGAGATTGTGTGGGTCTCATCGAGGTGGTAAGAAGTTCTCACACCATCATGCAGATTCAATGTAAAGGAGGCCTGAAGGGTGCGCTGCAGTTTAACAGTACAACGCTGCATCAGTGGCTAAAAGACAAGAACAAGGGTGAAATGTAAGTTCAAATTCAAACCAAATACACACAATTAAAAACAAAGGAAGGTGTTTGGAGTAACCAGTCGAAATGTTTATAGGTA[C/A]GACATGGCTATAGACTTGTTTACGCGATCCTGTGCTGGCTATTGTGTGGCCACTTTCATTCTGGGTATTGGTGACAGGCACAACAGTAACATCATGGTGAAGGATGATGGGCAGGTGGGAATGTTGTTTTTATGCCTTAAAACCAATACTTGATTCAGTTATTGTCAGTATTTCCACACTGAGCATCTGCATTGTTTCTACAGCTGTTTCATATAGATTTTGGTCACTTTTTGGACCACAAGAAGAAGAAGTTTGGCTACAAGCGAGAGCGAGTGCCGTTCGTCTTGACTCAAGACTTCCTAATTGTGATCAGCAAAGGAGGAACCCAGGAGTGCACTAAAACCAGAGAGTTTGAGAGGTGCGTATGCTGGAAAAAATCGCCAATTTATTTCCAGAGTGAACGTATGCGAAAACAAATTCTTTGTTGTTTCACCATTAACATAGTAATTGGCAGTCAGCAAACTGTCTGAGACAATCAGAGATTGAGCAGAACAATAGAG
Associated Phenotype:
Not determined