Busch Lab

ZMP

LOC556118

Ensembl ID:
ENSDARG00000022334
Human Orthologues:
KRT14, KRT16, KRT20, KRT23
Human Descriptions:
keratin 14 [Source:HGNC Symbol;Acc:6416]
keratin 16 [Source:HGNC Symbol;Acc:6423]
keratin 20 [Source:HGNC Symbol;Acc:20412]
keratin 23 (histone deacetylase inducible) [Source:HGNC Symbol;Acc:6438]
Mouse Orthologues:
Krt14, Krt16, Krt20, Krt23
Mouse Descriptions:
keratin 14 Gene [Source:MGI Symbol;Acc:MGI:96688]
keratin 16 Gene [Source:MGI Symbol;Acc:MGI:96690]
keratin 20 Gene [Source:MGI Symbol;Acc:MGI:1914059]
keratin 23 Gene [Source:MGI Symbol;Acc:MGI:2148866]

Alleles

There are 9 alleles of this gene:

Allele Name Consequence Status Availability
sa35042 Nonsense Mutation detected in F1 DNA Not yet available
sa17190 Nonsense Available for shipment Available now
sa24888 Essential Splice Site, Missense Mutation detected in F1 DNA Not yet available
sa38831 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa18652 Nonsense Available for shipment Available now
sa13306 Nonsense Available for shipment Available now
sa2612 Nonsense F2 line generated Not yet available

Mutation Details

Allele Name:
sa35042
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000041914 None None 365 None 7
ENSDART00000125446 Nonsense 165 741 1 7
Genomic Location (Zv9):
Chromosome 11 (position 12281680)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 12192097
GRCz11 11 12175718
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCTTTACCTGCCCCGAGACCTGTCTGAAAACTTGCTCTGAGACCTGTTCC[A/T]AGCCCAGTTCCTTCACCTGCCCTGAGACGTGTATTAAAACCTCATCTGAC
Long Flanking Sequence:
GATCCACCATGGCATGCTCCAAAACCTACCCTGAGACTTGTTGGAAGACCTGCTCTGAATCCAGCCCTGAGACTTACTCCACAAGCTGCTCAGAGACCTCTGAGATCTGCCCCAAGCCTTGCTCCTTCACCTTCCCCGAGACTTGCAGGAAGACTTGCTCTGAGACCAGCTCTGACTCCTGCCTGAAGACCTGCCCTGAAACCTGTTCTACCCAAAGCTACCCAGAGACCTGCTATGAGAGCTGCCCCAAGCACTGCTACTCCACCTGCCCTGAAATCTGCCCTAAGCCTTCCTCGTTCACCTGCCCCAAGACCTGTCTGAAGACTTTCTCTGAGAGTAGCTCCATAACTTGCCCTGAGACCTGCTCCAACACCTGCACCGCACCCTGTTCTTTCACCTGCCCTGAGACCTGTCTGAAAACTTGCTCTGAGACCTGTCCCAAGCCCTGTTCCTTTACCTGCCCCGAGACCTGTCTGAAAACTTGCTCTGAGACCTGTTCC[A/T]AGCCCAGTTCCTTCACCTGCCCTGAGACGTGTATTAAAACCTCATCTGACATCTGCTCCAAGCCCTGTTCCTTCACCTGCCCTGAGACCTGTCCCAAGTCTTTTTCAATCACCTGCCCCCAAACCTGCTCCGAGACCTGTCTGAAAACTTGCTCCGATACATGTCCCAAGCCCTGTTCCTTTACCTGCCCTGACACCTATCTTAAAACTTGCTCTGAGACATGCTCTGAGACCTGTCCCAAGCCCTGTTCCTTTACCTGCCCTGAGTCCTGTCTTAAAACGTACTCTGAGACCTGCTCTGATACACTCTCCAAGTCCTGCTCCTTCAACAACCCCAAACCCTGCCCTGACAACTGTCTGAAGACCTGCTCTGAGACCTGCTCTACAACTTGTTCTGAGACCTGCTCCAAGCCCTGTTCATTCACCTTCCCTGATACTTGTCCGAAGACTTGCCCGGAACCCTGCACCTCAAGCTGCCCAGAAACCTCATCTGAAACCTGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17190
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000041914 None None 365 None 7
ENSDART00000125446 Nonsense 231 741 1 7
Genomic Location (Zv9):
Chromosome 11 (position 12281480)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 12192297
GRCz11 11 12175918
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGCTCCGATACATGTCCCAAGCCCTGTTCCTTTACCTGCCCTGACACCTA[T/A]CTTAAAACTTGCTCTGAGACATGCTCTGAGACCTGTCCCAAGCCCTGTTC
Long Flanking Sequence:
ACCTGTTCTACCCAAAGCTACCCAGAGACCTGCTATGAGAGCTGCCCCAAGCACTGCTACTCCACCTGCCCTGAAATCTGCCCTAAGCCTTCCTCGTTCACCTGCCCCAAGACCTGTCTGAAGACTTTCTCTGAGAGTAGCTCCATAACTTGCCCTGAGACCTGCTCCAACACCTGCACCGCACCCTGTTCTTTCACCTGCCCTGAGACCTGTCTGAAAACTTGCTCTGAGACCTGTCCCAAGCCCTGTTCCTTTACCTGCCCCGAGACCTGTCTGAAAACTTGCTCTGAGACCTGTTCCAAGCCCAGTTCCTTCACCTGCCCTGAGACGTGTATTAAAACCTCATCTGACATCTGCTCCAAGCCCTGTTCCTTCACCTGCCCTGAGACCTGTCCCAAGTCTTTTTCAATCACCTGCCCCCAAACCTGCTCCGAGACCTGTCTGAAAACTTGCTCCGATACATGTCCCAAGCCCTGTTCCTTTACCTGCCCTGACACCTA[T/A]CTTAAAACTTGCTCTGAGACATGCTCTGAGACCTGTCCCAAGCCCTGTTCCTTTACCTGCCCTGAGTCCTGTCTTAAAACGTACTCTGAGACCTGCTCTGATACACTCTCCAAGTCCTGCTCCTTCAACAACCCCAAACCCTGCCCTGACAACTGTCTGAAGACCTGCTCTGAGACCTGCTCTACAACTTGTTCTGAGACCTGCTCCAAGCCCTGTTCATTCACCTTCCCTGATACTTGTCCGAAGACTTGCCCGGAACCCTGCACCTCAAGCTGCCCAGAAACCTCATCTGAAACCTGCCCCAAGCCTTGCCCCATCTCCAACCCCAAGTCCTGCTTTAGCACCTTCTCCAATAGCTGTTCCGTGTCTTCAGTGACCGTTCCTCGTCATTGTAGAACAGTTACAACAAAAGCCCACAGTGTATATGGTTGCGGTGTTGGAGGAAGGACCCGCATCTCTTCTTGCTCCTATCGTCCAAATACTTGCTCCCCATGTCCATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24888
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > G
Consequence:
Essential Splice Site, Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000041914 Essential Splice Site 48 365 None 7
ENSDART00000125446 Missense 420 741 1 7
Genomic Location (Zv9):
Chromosome 11 (position 12280915)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 12192862
GRCz11 11 12176483
KASP Assay ID:
554-7579.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GATTCGGTGAAAGATTTGGTGCTAGAATCATGGCTGGAGGGTGTTATGGC[A/G]GGGATTATGACTATCACCAGTTGAATGAGAAGGCCACCATGCAAAACCTG
Long Flanking Sequence:
AGTCCTGTCTTAAAACGTACTCTGAGACCTGCTCTGATACACTCTCCAAGTCCTGCTCCTTCAACAACCCCAAACCCTGCCCTGACAACTGTCTGAAGACCTGCTCTGAGACCTGCTCTACAACTTGTTCTGAGACCTGCTCCAAGCCCTGTTCATTCACCTTCCCTGATACTTGTCCGAAGACTTGCCCGGAACCCTGCACCTCAAGCTGCCCAGAAACCTCATCTGAAACCTGCCCCAAGCCTTGCCCCATCTCCAACCCCAAGTCCTGCTTTAGCACCTTCTCCAATAGCTGTTCCGTGTCTTCAGTGACCGTTCCTCGTCATTGTAGAACAGTTACAACAAAAGCCCACAGTGTATATGGTTGCGGTGTTGGAGGAAGGACCCGCATCTCTTCTTGCTCCTATCGTCCAAATACTTGCTCCCCATGTCCATTATACAAACTTGATGGATTCGGTGAAAGATTTGGTGCTAGAATCATGGCTGGAGGGTGTTATGGC[A/G]GGGATTATGACTATCACCAGTTGAATGAGAAGGCCACCATGCAAAACCTGAACGATCGTCTGGCGTCCTACCTGGATAAGGTGCACTTTTTAGAGGCTGCCAATGCCACTCTGGAGAAGCAGATCTGTGATTACTTTGAGAAGAAAGACCCAATCTGTCAGAAAGACTACAGCTGCTACCTGAAAACCATTGACTGCCTTCAGAAAAAGGTAAAACTTGAAAGATTAAAGACAATTAAGGGTGGATATGTTTTTTTATTATTATTATATTGCAAAAACCAAGTATGAGGTCTAAATTATGTAACACATTTCAGCACTTTGTGTTGTAATACCCTTGAATTAAAAGTTTGCAGGCACCCCAAGCAACACAATGCAATCTTTTTAATATAAAACTATTTTGAGTGTGAAAAACAACTGTATAAAATAATTGTTTAATAGCCTGATTTATCTTTGCGTTTTTCTATGCCCATGCTCTTTCTCATAGATTAAAGATGCTACAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa38831
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000041914 Essential Splice Site 117 365 2 7
ENSDART00000125446 Essential Splice Site 489 741 1 7
Genomic Location (Zv9):
Chromosome 11 (position 12280705)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 12193072
GRCz11 11 12176693
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGAAAGACTACAGCTGCTACCTGAAAACCATTGACTGCCTTCAGAAAAAG[G/A]TAAAACTTGAAAGATTAAAGACAATTAAGGGTGGATATGTTTTTTTATTA
Long Flanking Sequence:
GCCCAGAAACCTCATCTGAAACCTGCCCCAAGCCTTGCCCCATCTCCAACCCCAAGTCCTGCTTTAGCACCTTCTCCAATAGCTGTTCCGTGTCTTCAGTGACCGTTCCTCGTCATTGTAGAACAGTTACAACAAAAGCCCACAGTGTATATGGTTGCGGTGTTGGAGGAAGGACCCGCATCTCTTCTTGCTCCTATCGTCCAAATACTTGCTCCCCATGTCCATTATACAAACTTGATGGATTCGGTGAAAGATTTGGTGCTAGAATCATGGCTGGAGGGTGTTATGGCAGGGATTATGACTATCACCAGTTGAATGAGAAGGCCACCATGCAAAACCTGAACGATCGTCTGGCGTCCTACCTGGATAAGGTGCACTTTTTAGAGGCTGCCAATGCCACTCTGGAGAAGCAGATCTGTGATTACTTTGAGAAGAAAGACCCAATCTGTCAGAAAGACTACAGCTGCTACCTGAAAACCATTGACTGCCTTCAGAAAAAG[G/A]TAAAACTTGAAAGATTAAAGACAATTAAGGGTGGATATGTTTTTTTATTATTATTATATTGCAAAAACCAAGTATGAGGTCTAAATTATGTAACACATTTCAGCACTTTGTGTTGTAATACCCTTGAATTAAAAGTTTGCAGGCACCCCAAGCAACACAATGCAATCTTTTTAATATAAAACTATTTTGAGTGTGAAAAACAACTGTATAAAATAATTGTTTAATAGCCTGATTTATCTTTGCGTTTTTCTATGCCCATGCTCTTTCTCATAGATTAAAGATGCTACAATCACCAATGGCAAAATCCTACTCCGAATCGACAACTCTAAACTGGCTGCTGATGACTTCAGGATAAAGTGAGTTCTCTAAAGTCATTTTCACATTTACTTCATTTAGAGCAATGGACTCAAACTCAAATCCCCAAGAGCCGCAGCTCTGCATAGTTTAGCTTCAACCACCTCCAGCTCACACCTGCTAAATAGTCTGTAGTAGTCTTGAGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18652
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000041914 Nonsense 190 365 4 7
ENSDART00000125446 Nonsense 562 741 3 7
Genomic Location (Zv9):
Chromosome 11 (position 12278987)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 12194790
GRCz11 11 12178411
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AAGGCCGACCTGGARTTGCAGATCTGCACTTTGGARGAGGAACTTGTGTA[T/A]TTGAGAAAAACTCACCARGAGGTTGGTAGCTGTTTCTCTATAGCAGAATA
Long Flanking Sequence:
TTCAATACTTGTGTTTTGCTGTGAAAATACACAAAAATAATAAAAATCTTTTTCTTTTTGATTTAAAGAATACCGTTTGACTAGACTATTAGACAAAATCCAATGACCAATAAAAAATAACTCAGACCCTAATTCTTTAGATTTACTATTTGTTAAATGCACTGCTTTCCCATGGATGGGTTGCAGCTGGAAGGGCATGCGATGCGTAAAAACTTGCTGGAAAAGTTGGGGGTTCATTCTGCTGTGGCGACCCCGGATTAATAAAAGGACTAAGCTGAAAAGAAGATGAATGAATGAATGAATAAATGCACAGATAGCTACTTTGTTCGTGTAAGTCATAGATATGTTTCATCCTCTTTGGTCAGGTATGAGAATGAGCTGTCAATACATCAGTGTGTGAAGGCTGATATTGATAACCTGCGATGCATACTTGATAAGACATGCCTGGCAAAGGCCGACCTGGAGTTGCAGATCTGCACTTTGGAGGAGGAACTTGTGTA[T/A]TTGAGAAAAACTCACCAAGAGGTTGGTAGCTGTTTCTCTATAGCAGAATAGCTATAACAACCTAAACGCTATGCTTCAAAAGCCTTAATGCTTCAGTTATGTGTGTTTACAGGATGTGGCGGCACTAATGTGTCAGTTGACAAACTCAAAGGTGTGTGTTGAAGTGGACGCCGCTCCTCAGCAAGACCTCAAAAAGGTTTTGGATGACATCCGTTGTTATTATGACACCATCATAGACAAACACTGCACAGAACAGGAGTGCTGGTTCAAAGAGAAGGTGAGACTTTGATATCTTCAACTCCTCTAACTATACCATATAACATATAGTGAAACACAAGCTTTGTTTCTCATGAGTTAAACAGCATGATGTGTGTTTGTGATCTTCTTTAAGATGGCAGGTCTATGTAAAGATACTGCAATCAACACAGAGTGCCTGGAAACCTCCATGTCACGTATTTCTGATTTACGACGCACATTGCAGAGTCTGGAGATCGAGCTAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13306
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000041914 Nonsense 233 365 5 7
ENSDART00000125446 Nonsense 605 741 4 7
Genomic Location (Zv9):
Chromosome 11 (position 12278767)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 12195010
GRCz11 11 12178631
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCCGCTCCTCAGCAAGACCTCAAAAAGGTTTWGGATGACATCCGWTGTTA[T/G]TATGAMACCATCATAGACAARCACTGCACAGAACAGGAGTGCTGGTTCAA
Long Flanking Sequence:
AAAAGTTGGGGGTTCATTCTGCTGTGGCGACCCCGGATTAATAAAAGGACTAAGCTGAAAAGAAGATGAATGAATGAATGAATAAATGCACAGATAGCTACTTTGTTCGTGTAAGTCATAGATATGTTTCATCCTCTTTGGTCAGGTATGAGAATGAGCTGTCAATACATCAGTGTGTGAAGGCTGATATTGATAACCTGCGATGCATACTTGATAAGACATGCCTGGCAAAGGCCGACCTGGAGTTGCAGATCTGCACTTTGGAGGAGGAACTTGTGTATTTGAGAAAAACTCACCAAGAGGTTGGTAGCTGTTTCTCTATAGCAGAATAGCTATAACAACCTAAACGCTATGCTTCAAAAGCCTTAATGCTTCAGTTATGTGTGTTTACAGGATGTGGCGGCACTAATGTGTCAGTTGACAAACTCAAAGGTGTGTGTTGAAGTGGACGCCGCTCCTCAGCAAGACCTCAAAAAGGTTTTGGATGACATCCGTTGTTA[T/G]TATGACACCATCATAGACAAACACTGCACAGAACAGGAGTGCTGGTTCAAAGAGAAGGTGAGACTTTGATATCTTCAACTCCTCTAACTATACCATATAACATATAGTGAAACACAAGCTTTGTTTCTCATGAGTTAAACAGCATGATGTGTGTTTGTGATCTTCTTTAAGATGGCAGGTCTATGTAAAGATACTGCAATCAACACAGAGTGCCTGGAAACCTCCATGTCACGTATTTCTGATTTACGACGCACATTGCAGAGTCTGGAGATCGAGCTACAGTCTCAAATCAGCCTGGTGAGTAAGAGACATAATACCGAATGTTATAAACATCCTGGTAAAAATATTATTTTGTCTTCTGCAGCAAAGTTCCTTGATTTTTATGCCAGAATGATGATATAGTTTTTAACCATTTTGACAGAAAATATCAACTTAAAAATGTTTGTCAGTCTTACCATATAACTACAGAAGAGTCAAGCTTTAAATGGTAAAATTAGTCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2612
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000041914 Nonsense 316 365 7 7
ENSDART00000125446 Nonsense 688 741 6 7
Genomic Location (Zv9):
Chromosome 11 (position 12273285)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 12200492
GRCz11 11 12184113
KASP Assay ID:
554-3284.1 (used for ordering genotyping assays)
KASP Sequence:
TGTTCACTGCTGGAAACAGAGGCGCGTTACAGCACTATGCTAGCAGGCTA[T/G]CAGAAACACATCAACGCATATGAGGCAGAGCTCKGTCAGGTTCGCGCYGG
Long Flanking Sequence:
GTGAGGCAACAGTGCTAGCCACTGGGCCACCGTGTCGCCCGATCAGAAAAAGTGGGAGGATGTAGGGGTGGAAGGGGGGGAGCTTCAAGACGAAGATAACTGGAGGGGAAAACTCAGGTTATTTATAATGCTTCTGTAATCATCTAATAGGGCTGATTACGGAGCTAACAAGGAGCCAGCCGTGTTGATTATAAGCATGTGATCCTCTCGAAATTAGTTTATGAATAAACCACACTTAACTGTTTGGTATGAAAAAGTAGAAAATATTTATATATTTATATTTACCAGCTAAAATATTTGCTATCAAATCTAAAGAGTTACAGGAACCGATACCAATAAACATATCGGTATCTGTATCAGTCAAGAATTCCATATTAGTTCATCCCTAGTAAATTTGTCTCTATTTTCTTTCTAACTCTTTCAACGCCAAAACAGAAAGGAGCTCTGGAGTGTTCACTGCTGGAAACAGAGGCGCGTTACAGCACTATGCTAGCAGGCTA[T/G]CAGAAACACATCAACGCATATGAGGCAGAGCTCTGTCAGGTTCGCGCTGGCATTGAGCAGCAGGGCAGAGATTATGATGCCCTGCTGGACATCAAGAGCCGCCTGGAGCAGGAGATCGCCACCTACAGGTGCCTCCTGGAAAACCAGGCCTCTCAGTGAGTTCTTTTTCTCATTCAGATGAGTGTCGCAGTTGAAGGGTTTTACGTAATGTGATTATTCCCTGGTTTGACATGCGTCTTTTTGTCTTTCTTTTCTAGGTGCTGAAATTAGGTCATCACAATCTGTCTCTCCCTCAGTCTAGATCACATAAAACATTTTAACACATTTACCCTCTATTTATATGGTCGAACTGCAGTTTTAAGTTCCAGCACTTCATTATCATTCTGATAGAGTTGTGATGTGTGTTTCATATTAAAAATCAGCTCCAGTATTCTGGTGTCCGTTTCTTTTTTGTGTTTTGTTTGTTACATGCATGCAAACATACACATTTGTGACACATT
Associated Phenotype:
Not determined