Busch Lab

ZMP

A0JMQ5_DANRE

Ensembl ID:
ENSDARG00000063527
Description:
LOC100006857 protein [Source:UniProtKB/TrEMBL;Acc:A0JMQ5]
Human Orthologue:
ELMO2
Human Description:
engulfment and cell motility 2 [Source:HGNC Symbol;Acc:17233]
Mouse Orthologue:
Elmo2
Mouse Description:
engulfment and cell motility 2, ced-12 homolog (C. elegans) Gene [Source:MGI Symbol;Acc:MGI:2153045]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa17632 Essential Splice Site Available for shipment Available now
sa41743 Nonsense Mutation detected in F1 DNA Not yet available
sa34996 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa17632
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000092903 Essential Splice Site 348 541 10 15
Genomic Location (Zv9):
Chromosome 11 (position 157360)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 89855
GRCz11 11 95867
KASP Assay ID:
2260-3748.1 (used for ordering genotyping assays)
KASP Sequence:
GTCAGTCCGAGAGAATGAGCCAAGATGACTTCCAGTCGCCGCCCATCATG[T/C]GAGTCCAGAAGACCAGCAGTGAACACCCAGATCATCCTCAGAGCAGTATT
Long Flanking Sequence:
CTTCACACACGAGCGCGCCTGGGAAGAGTTCTTCTGCGTCTGCATACAGCTGCTCAACAAGACATGGAAGGAGATGAGGGCCACTGCTGAAGACTTCAACAAGGTGTGTGTGTGTGTGTGCACATGTGCCTGTGTGTCAGTGTGTGCTTATATATCTGTGTATGTGTGTGTGTACATTGTATTACTGTGGAGCAAATTGTCCCGCAGGTATAGGAACAGAAGCAGATCTCCACCTTTTGTGTTTGTTTTTTTGGTCCCCGCGAGGAAAACGGCTCATAAATCAGACAGATGGAGTATTTTGAAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTAGGTGATGACGGTGGTGCGTGAGCAGATCACCCGGGCTCTGGCCCTGAAGCCTGCGTCTCTGGATCAGCTGCGGCTGAAGCTGCGCTCTCTGAGTTACTCTGAGATTCTGCGACTGCGTCAGTCCGAGAGAATGAGCCAAGATGACTTCCAGTCGCCGCCCATCATG[T/C]GAGTCCAGAAGACCAGCAGTGAACACCCAGATCATCCTCAGAGCAGTATTGATCATTGAGTGTTTTATTGATTATTGGTCGCTGTGTTGATCATTGTGTTGTGTTGTTGTTCAGTGAGCTGCGGGAGCGGATCCAGCCGGAGATCCTGGAGCTCATCAAGCAGCAGAGGCTCAGTCGGCTCTGTGAGGGAAGCTGCTTCCGCAAACTGGGGAACCGACGCCGGCAGGGTGAGCAGACTGACCCTAACCCTGACTCTGACTCTGATCCCGACCCTGACATTAACCTTGACCCTAACCACAACCCAGGCCCGGCGCCAGGATGTCAGAACTGAGGGGGCATTTTAAATCCATAGGGGGGCACTAGACCTGTTGGCTGATGTTGGTCTCTCTTGTTCCTTTCATTTAGGCTATTTATTCACATTTATTATTACTTTACTTTGTTACTGACCTAAGGCAGTAATATACGTTTTAATAGTAATAATAATATGCACAGTTTCGCTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41743
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000092903 Nonsense 410 541 12 15
Genomic Location (Zv9):
Chromosome 11 (position 155032)
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTCACTGAACCACAAGCTGCTCCATTATGGGGATCTGGAGGAGTCTCCA[C/T]AGGGTGAGGTGCCACTGGAGCTGCTGACCGACAAGAGTGAGTGCTTATAT
Long Flanking Sequence:
CACTTTTCTCCCTTGTGAGTTGAGTGCGCTTCCACCGCCGTGTGCGCGTTTTAAAGGCTATTTACGGGCGCACCTGACCTAACGCGGGGACCGGATCTCTGGACTATAGGACTATCTTTAATCTCACAATTTTCATAATTCAATTGCTATGTCATATATTTTAAAATATTTAAATGTGTGTTCTAAAGGTTGGAACGACGGGAGTGTTAATAATTTATGACAGAAAGAATTTTCCGTTTTGAGTGAACAATCCTTTATAAAAACTGGGGGGGCACAAATTCTTTCTGAGGGGGCAATGCCCCCCTTTGCCCCCCCGTAGCGCCGGGCCTGCCACAACCCTAACCCTGACTCTAACCCTGACCCACAGCAGAGTCAGTGTATTAGTGTACTGTTAGTAATCTTGTATAATCCACTGTCTCCGTCCCTCAGAGAAGTTCTGGTTCTGCCGGCTCTCACTGAACCACAAGCTGCTCCATTATGGGGATCTGGAGGAGTCTCCA[C/T]AGGGTGAGGTGCCACTGGAGCTGCTGACCGACAAGAGTGAGTGCTTATATCAGCGTATAAACACACGCTGAGCTTATAGAGTGCTTATATCAGCGTATAAACACACACGCTGAGCTTATAGAGTGCTTATATCAGTGTATAAACACACGCTGAGCTTATAGAGTGCTTATATCAGCGTATAAACACACACTGAGCTTATAGAGTGCTTATATCAGCGTATAAACACACACTGAGCTTATAGAGTGCTTATATCAGCGTATAAACACACAGGCTGAGCTTATAGAGTGCTTATATCAGCGTATAAACACACGCTGAGCTTATAGAGTGCTTATATTAGTGTATAAACACACGCTGAGCTTATAGAGTGCTTATATCAGCGTATAAACACACACTGAGCTTATAGAGTGCTTATATCAGTGTATAAACACACGCTGAGCTTATAGAGTGCTTATATTAGCGTATAAACACACGCTGAGCTTATAGAGTGCTTATATCAGCGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34996
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000092903 Essential Splice Site 476 541 15 15
Genomic Location (Zv9):
Chromosome 11 (position 151088)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 83583
GRCz11 11 89595
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GATGCGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTCACCA[G/T]TACTGTATCTGGACAGACGGCCTGTCAGCTCTGCTAGGGAAGGATCTGTC
Long Flanking Sequence:
GTTCAAGGGCTGATTGATGAAGCCATGTCCACTAACCGCTCGCTCCTTCAGCATTACTGAACTACAGCCAGGATGAAGGAGACACACATTAAAATAGACCTCAGACTTGTGTTGCAGAACCATATTAATGCCAGATCATATTCAACCCATTTGTGTTGGTCGTTATTAGGATTAATTAGTTCAGCTGGAGAACACACACTCTCGCTTTCCCCCTCTGATGACACGTACAAATGGAGAATGTCAATCACAGTCTGATTAACCAGTCACGATCTTTACCATTAGAGGCTGCTGGAGATACTCACACACTGCTGACACACACACACACACACACACACACACACACACTACCTGGGGTTAAACCCTGCACAATAGTGAGTTTTACATAATAAGTGCCCTTTCATGTCTGGTTTGTTCTGCTGTTGTGTGGTTTATCTGGTGTTTGCTGACAGTGATGCGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTCACCA[G/T]TACTGTATCTGGACAGACGGCCTGTCAGCTCTGCTAGGGAAGGATCTGTCCAGTGACCTCACACGAAGTGACCTTGACACACTAATGAGTATGGAGATGAAGCTCCGCCTCCTGGACCTGGAGAACATCACCATCCCTGAGGCTCCGCCCCCCGTGCCCAAAGAGCCCAGCAGCTACAACTTCAGCTACAACTACGGCTGAGCGGCGGCGCGGAGTGTGTGTGTTATAGAGACGGCACACACACTTTACTGAACACACACCGTACGAGTTCTCCATTCCTTCATGTCAGAAACACTCTGCTGTGCGTGTGTGTGCGTGTGCGTGTGTGTGTGAAACGCTTCAACTAAACAGAAGGGTTAGCTCCTTTATACACACAGATGACTAATATTTGCTGATGTTTGATTTGTCAATAGAAATCTATTTTTGTACGTGATGTGAAAGACGTGACGCTGCATGAAGCGGAGGAGAACTCAGATCCACACACACACACAGACACACCC
Associated Phenotype:
Not determined