Busch Lab

ZMP

xrcc4

Ensembl ID:
ENSDARG00000010732
ZFIN ID:
ZDB-GENE-040426-1755
Description:
DNA repair protein XRCC4 [Source:RefSeq peptide;Acc:NP_957080]
Human Orthologue:
XRCC4
Human Description:
X-ray repair complementing defective repair in Chinese hamster cells 4 [Source:HGNC Symbol;Acc:12831
Mouse Orthologue:
Xrcc4
Mouse Description:
X-ray repair complementing defective repair in Chinese hamster cells 4 Gene [Source:MGI Symbol;Acc:M

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa34984 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa34985 Nonsense Mutation detected in F1 DNA Not yet available
sa13686 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa34984
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000024644 Essential Splice Site 50 357 3 8
Genomic Location (Zv9):
Chromosome 10 (position 44609078)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 43300391
GRCz11 10 43128771
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGGTTGTATTTTATTTGGTTTTAAACTCTAGCTCTGGTTGTTTTTTGTTC[A/C]GTTTCCGAGGAGGACGTGTCGCGGGAGGCTCGTGAGATGGAGATGGAGCG
Long Flanking Sequence:
CAGTCCAAAGACATGCGGTACAGGTGAATTGGGTAGGCTAAATTGTCCGTAGTGTGTGTGTGTGTGTGTGAATGTGTGTGGATGTTTCCCAGAGATGGGTTGCGGCTGGAAGTGCATCCGCTGCGTAAAAACTTGCTGGATAAGTTAGCTGTTCATTCCGCTGTGGCATCCCTGAATTAATAAAGGGACTAAGCCGACAAGAAAATTAATGAATGAATGAATGAATATATAGTTAAAATATATATTTACTATTTTCCCAAGTGTATATAACTACTACTGTAAGATAATATCAGCATTTGGTACATATTTTCAGTATTATCTTAGCTTGGACTGACCCGATCTAATCCCGTTTATATGAAATGAACCTGCTCCCAAGCAGGTTTGAGCTACCACAACTGTTGCTAAGACGTCAGAGAATGTTTTCATCAAGATTTATAAAATCATCTAACCTGGTTGTATTTTATTTGGTTTTAAACTCTAGCTCTGGTTGTTTTTTGTTC[A/C]GTTTCCGAGGAGGACGTGTCGCGGGAGGCTCGTGAGATGGAGATGGAGCGTGATCGGTATGTCTGTGACCTGCAGCTGGCCCTGACCGGAGCACCATCAGGATCTGGAGCTTCAGATGAGGGTGAATTTACCTTCCAGCTGACACCTGAGCGGCCCGGACGACCCCAACTGCAGCTGTCTTATGAGAAGGTGCAGAAGGACATCTCGGTGAGTCTCGATGAATGACACTGAAACACACACGCTTTATAATCAACACTCCAGCAGCTGACTCAACATTACACTGATTTTGAGGTTTTGTGTACCGTGTAGGTAAAGTCAGATTTTAAGAATCATGGTCAGGTCCTTGATTATGTAGGAAACAACTTGATCCAAATTGGGAAAAAGTGAATTACCAGAGATCAAATCACTGCCAATTTAGAGTCTTCTAATGACCTTTTTTGTTTTTCACATATTTTTTTATTTATCTTCCAGAGGTTTTCTTATTTTTGTTCATCAGTCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34985
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000024644 Nonsense 110 357 3 8
Genomic Location (Zv9):
Chromosome 10 (position 44609261)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 43300574
GRCz11 10 43128954
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCCAGCTGACACCTGAGCGGCCCGGACGACCCCAACTGCAGCTGTCTTA[T/A]GAGAAGGTGCAGAAGGACATCTCGGTGAGTCTCGATGAATGACACTGAAA
Long Flanking Sequence:
AGGGACTAAGCCGACAAGAAAATTAATGAATGAATGAATGAATATATAGTTAAAATATATATTTACTATTTTCCCAAGTGTATATAACTACTACTGTAAGATAATATCAGCATTTGGTACATATTTTCAGTATTATCTTAGCTTGGACTGACCCGATCTAATCCCGTTTATATGAAATGAACCTGCTCCCAAGCAGGTTTGAGCTACCACAACTGTTGCTAAGACGTCAGAGAATGTTTTCATCAAGATTTATAAAATCATCTAACCTGGTTGTATTTTATTTGGTTTTAAACTCTAGCTCTGGTTGTTTTTTGTTCAGTTTCCGAGGAGGACGTGTCGCGGGAGGCTCGTGAGATGGAGATGGAGCGTGATCGGTATGTCTGTGACCTGCAGCTGGCCCTGACCGGAGCACCATCAGGATCTGGAGCTTCAGATGAGGGTGAATTTACCTTCCAGCTGACACCTGAGCGGCCCGGACGACCCCAACTGCAGCTGTCTTA[T/A]GAGAAGGTGCAGAAGGACATCTCGGTGAGTCTCGATGAATGACACTGAAACACACACGCTTTATAATCAACACTCCAGCAGCTGACTCAACATTACACTGATTTTGAGGTTTTGTGTACCGTGTAGGTAAAGTCAGATTTTAAGAATCATGGTCAGGTCCTTGATTATGTAGGAAACAACTTGATCCAAATTGGGAAAAAGTGAATTACCAGAGATCAAATCACTGCCAATTTAGAGTCTTCTAATGACCTTTTTTGTTTTTCACATATTTTTTTATTTATCTTCCAGAGGTTTTCTTATTTTTGTTCATCAGTCAGGTTTTGTTGGTGTGTTTAGTCCACTTCAGTCATTTTCAAAAAATATATCAAATTTAACGGCTAACACACTTCATTCATTCATTCATTCATTCATTTATTATTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCAATCAATCGTTTATC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13686
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000024644 Nonsense 185 357 5 8
Genomic Location (Zv9):
Chromosome 10 (position 44629507)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 43320840
GRCz11 10 43149220
KASP Assay ID:
2260-3684.1 (used for ordering genotyping assays)
KASP Sequence:
TCTCTCTGTGTTTTTCAGGATGGAWCGATACGTGAAGGGAAAGGAGGCGT[T/A]AGAGAGAGACCTGTACRGCCGCTTTGTGCTGGTCCTCAATGAGAAGAAAG
Long Flanking Sequence:
CGCAGTGGGTAGCACATTTGCCTCACATCAAGAAATCTGCTGGTTCGAGCCCCGGCAGGGTCAGTGGTCATTTCTGTGTGGAGTTTGCATGTTCTCCCTTTATTGTGTGCTCTGATTTCCCCCACAGTCCAAACACACGCGCTGTAGGGGAATTGATGAACTACATTGGCTGTAGTGTATGTGAGTGTGTGCAAGAGCGTGTGGGTGTTTTCCAGTGTTGGGTTGCTGCTAAAAGGGCATCCGCTGCGTATAACATTTTATGGATAAGTTGAGGGTTCATTTTGCTGTGGCGACCCCTGATTAATAAAGGGACTAAGCCGAAAATGAATGAATGAGATCTGTCACACCGCCCAGCCCTAGTTGAGTGTTTATCTGCTTTAAAACCACCAAAGTAATACAAACACCCCCGCAACTAAACATTTCCACTCCTGTCCATGCCAGCTATTTAGATCTCTCTGTGTTTTTCAGGATGGAACGATACGTGAAGGGAAAGGAGGCGT[T/A]AGAGAGAGACCTGTACAGCCGCTTTGTGCTGGTCCTCAATGAGAAGAAAGCCAAACTCCGAGCCCTGCAGCAGAGGGTCCGAGAGCTGGAGGAGGCTGAGGAGGAGAGATCACCGAGGTAAAGAAGAAAGAAAAGACCAGCGCCACATTTCATCAGGATCTTTCTCTCACTTTTTCCCCGCTTTCCTGTTATTAAACATTCGATTTCGTTAGGTAATCCCATGATCGCATTACGCTGATTTCCACTTCCAGTTTTGTGTTGAGTCATTTTCCTGTCTGTGCTCATGATTCAAACTTAAAATGAGCAAAACATCTGTTCTAAAATTAGGAAGGTTTACAGTAGTCAGCAGTTGAAGTTGGACAGAGTAGTCCTAAAAATGATTTTTTTATCAACTTCAAATATTGAGTAATGTACACTCACCGGCCACTTTATTAGGTACACCTGTCCAACTGTTTGTTAACGCAAGTTTCTAATCAGCCAATCACATGGCAGCAACTCAA
Associated Phenotype:
Not determined