Busch Lab

ZMP

mpx

Ensembl ID:
ENSDARG00000019521
ZFIN ID:
ZDB-GENE-030131-9460
Description:
eosinophil peroxidase [Source:RefSeq peptide;Acc:NP_997944]
Human Orthologues:
EPX, LPO, MPO
Human Descriptions:
eosinophil peroxidase [Source:HGNC Symbol;Acc:3423]
lactoperoxidase [Source:HGNC Symbol;Acc:6678]
myeloperoxidase [Source:HGNC Symbol;Acc:7218]
Mouse Orthologues:
Epx, Lpo, Mpo
Mouse Descriptions:
eosinophil peroxidase Gene [Source:MGI Symbol;Acc:MGI:107569]
lactoperoxidase Gene [Source:MGI Symbol;Acc:MGI:1923363]
myeloperoxidase Gene [Source:MGI Symbol;Acc:MGI:97137]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa18566 Nonsense Available for shipment Available now
sa34835 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa21652 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa18566
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000043961 Nonsense 53 893 4 15
ENSDART00000111058 Nonsense 53 762 4 16

The following transcripts of ENSDARG00000019521 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 6813068)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 7825868
GRCz11 10 7784568
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGTCATTGATCTATCAGTTTTTTNAAATATATCTCYCAACCTTTAGGAGTT[T/A]AGCAAGGGTGCGCAAAGATGTCATTAAGCCTTCTGACAAGCTACGTCTGY
Long Flanking Sequence:
CACAATTTTAGTATTTAATAAATGTAAATGTAAAAAGTAATTTTAGTAATAAATGCAGCCTTGGTGAGCAGAATAAGCTTATTTTAAACATTTTAAAATCCCATTTTAAAAATTTTATGACCCCAAACTATTGACTGGCAGTGTACATCTGTGCATTGCTGCATGATTCAATGTGAAAACCAAGAAAAACAAGTTAAACAAAACAGATATTAATTATTAATGCCATGTGTAAGTGTGAACTTTTTCTCTTACTAGACAAGACTTTGGAGTCATTAAAATGAGTAATTATTATCTTTGTCTTTTTAGCAGAAGAAGAGAGTCCTGGAAGACCTTTTATTCTTGATTCAATTGAGGAAGCAAAGAAAATAGTAGACGCTGCTTACAAGTATTCTCGAGATGAGTGAGTAAAGTTTGTAAGAATGTTGCTCAGTACTCCTGTGTCACCATTCCAGTCATTGATCTATCAGTTTTTTAAATATATCTCTCAACCTTTAGGAGTT[T/A]AGCAAGGGTGCGCAAAGATGTCATTAAGCCTTCTGACAAGCTACGTCTGTTGAAACAGCCAGCTCGAAAGACACGGGAGGCCGTAAGAGCTGCAGACTACATGGCACAAACGCTGAGACTGATCAGTGAGAAAGCCCATCATGTACACAAGAGGTCCATCAATGCCACAAGTATGAAGACGAAATATTGTAAAACACTCAGGTCTTAGATCAGATCCATCACTGTGAAGTGGCATTCTGAATAATTTATTTGTTTCCTTCAGACCTGCTCACTCAAGACGAGCTTCAAACCATTACACGTATGACAGGCTGTGAAGCTCAAACCCGGCCACCATCTTGTAGGACCACACCCCTCATAAACAAGTATCGAACTGCCAGCGGTGTCTGCAACAATCGGTCAGTCTTCTGGATGAAATTCATATTGAGAGTAGTTTATACTGACAGTTGTTTATTGACAGCGTAATTTATTATTTCCAGGAAGAACCCACTTCTTGGTGCATC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34835
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000043961 Essential Splice Site 662 893 12 15
ENSDART00000111058 Essential Splice Site 662 762 12 16

The following transcripts of ENSDARG00000019521 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 6809798)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 7822598
GRCz11 10 7781298
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTGCCTGCCTGATTTCAAGACAGTTCCAGAAAATCCGAGATGGCGATAG[G/A]TAACAATCTTTCAGTGTTTAGTAGGGGTGTTTAATTTTTCTCCTAGAGGT
Long Flanking Sequence:
GGGCATTGATCCTGTGCTCCGTGGACTGATTGGTCGTCCGGCAAAACTGAACACCCAGGACCACATGTTGGTGAATGCTCTCAGAGAGAGGCTGTTTGCCTTCACATCCCACATAGCTTTGGATCTGGCTTCCCTCAACATGCAAAGAGGGCGTGACCATGCTATACCAGGCAAGTTTATCTCTGCTTCATGTTGCATCATCATTTTAAGTGTATTTTGGATTTAAGTCTGAATGGATATCCATTCGTTGTTCCTCTTATAGGTTATAATGCATGGCGTCGGTTCTGTGGATTGTCTGCTCCTCAGAATGAGCAAGAATTGGCTGTGGTGATGAACAACACTGAACTAGCCCGCAAGTTAATTGAGCTTTATGGCACCCCTGAGAACATTGATGTTTGGTTAGGAGGTGTTGCTGAGCCTTTTGCTCCTGGTGGTCGTGTCGGTTCTCTTTTTGCCTGCCTGATTTCAAGACAGTTCCAGAAAATCCGAGATGGCGATAG[G/A]TAACAATCTTTCAGTGTTTAGTAGGGGTGTTTAATTTTTCTCCTAGAGGTCCATTATCTTCTTTCCAACCTAATCTATTTATCAAAGTCTTTAAGAAAGTTCATCAGATGTGCTGGGTCATTCATAATTTTTTTTTTTTCGGCTTACTCTCTTTATTAATCAGAGGTCGCCACAGTGCCAACTTATTTAGCATATGTTTTACACAGCGAATGCCCTTCCAGCTGCAACCCATCACTGGGAAACCCCCATACATTCTCATTCACACACACATACACTACGGCCAATTTAGCTTATAGCACATGTCTTTGGACTTGTGGGAGAAACCGGGAAAGCGGTGGAAACTCACCTGAACAAAGGGAAAACATGCAAACTCCACAGAGAAATGCCAACTGACCCAGCCGAGGCTCGAACCAGTGCTGCGAGGCTTCTTGCTACTCACTGCTCCGCCGCACCGCCTGTGCTGGGTCATGTTAAGAGTTAAACTCTGCAAGACACTGCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21652
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000043961 Nonsense 869 893 15 15
ENSDART00000111058 None None 762 16 16

The following transcripts of ENSDARG00000019521 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 6807862)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 7820662
GRCz11 10 7779362
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTAGCTGAAGGGAAGGCAGTCCTGAGCCTACAGAGAGGAGACCGTGTGTA[T/A]GTGGAGGTTTCTCGAAGTGCTAATGGTATAGGCTTTTCAAGCTATTTCTC
Long Flanking Sequence:
AGGCATTGAAATGTCAAAAAAGTCCTCTAAATATTTTATCAACACACACACAAAAAAACCAAAACTAATGAATAGATAATAAATACCACAATATTCATTATAATTTTCTCCAATCTCTATTTTGTTTCAGGTCCACAGGGTGTAGCAGGGCCACCAGGACCTCCAGGAATTCCAGGACCTCCCATTAATACAACAGGACAACAGTCTGCCTTCTTTGCCTCAGTCAACTCCATCCTTCCTGCCACTGCTAAAGTTGTGGTGTTCGGTCAGGTCCTTTACAATGGACAAAACCATTATAACCAAACCTCAGGGATGTTCTTGTGCCAGATACCTGGTGTATATGAATTCGAGTTTTCATGCATAGGGACTCGTAGTTTGGGCTTTGTGACCTTAAAGAAAAATAATAGGGTAGAGCTTACTCCTGAAACAGTTGCTCTTAATACAAGGTCATTAGCTGAAGGGAAGGCAGTCCTGAGCCTACAGAGAGGAGACCGTGTGTA[T/A]GTGGAGGTTTCTCGAAGTGCTAATGGTATAGGCTTTTCAAGCTATTTCTCTGGCCACATTCTTTTTCCCGTTTGAGGCTATTACTTATAATGCATTACTATTTCCCTTTTTTTTTTGTTCATTTTAAATGCATTCTGCTTCTTTCTATTTGTCTTTAAACATGTTTCTTCTTACTGTAATGTCTTAGGCTCTGTTGTTGTTGTTGTTGTTTTATTAATAATTAGCTTTGCAAAATTAGTAGTATGGTTAGAGAATGCCTTATGTTTTAATTCAGAATTTTTTACAGGTAAATAAGTGATAAAATTTCAGAACCAAGATTTAACTGCTAATGCATTGACCTTTCTTTTATGAAGTTTTTTTTTTTATTTGTTGTTTTTGGTTTTGTTGTCAGATTGCAACAAAATTTTCGGTAGTCCATGCTGTGACAGTTATTTTTGTGTATGCTTTTAGCAAAGTAAAAAAACTAATAAATAAAGTTTTTTGTCAATATTATTGGGCTG
Associated Phenotype:
Not determined