Busch Lab

ZMP

plcl1

Ensembl ID:
ENSDARG00000067676
ZFIN ID:
ZDB-GENE-090313-194
Description:
Novel protein similar to vertebrate phospholipase C-like 1 (PLCL1) [Source:UniProtKB/TrEMBL;Acc:B8JI
Human Orthologue:
PLCL1
Human Description:
phospholipase C-like 1 [Source:HGNC Symbol;Acc:9063]
Mouse Orthologue:
Plcl1
Mouse Description:
phospholipase C-like 1 Gene [Source:MGI Symbol;Acc:MGI:3036262]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa31726 Nonsense Available for shipment Available now
sa21517 Essential Splice Site Available for shipment Available now
sa41457 Nonsense Mutation detected in F1 DNA Not yet available
sa34681 Nonsense Mutation detected in F1 DNA Not yet available
sa2490 Essential Splice Site F2 line generated Not yet available

Mutation Details

Allele Name:
sa31726
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000097475 Nonsense 244 1137 2 8
ENSDART00000136894 None None 464 None 6
ENSDART00000144608 Nonsense 252 578 2 3
Genomic Location (Zv9):
Chromosome 9 (position 33466021)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 32621967
GRCz11 9 32432713
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGAGGAACTGGTTGGTGGCTGAGTTTGCTCTGGTTGATGAGGATGGACAC[G/T]GAATTGTGTCTGAAGATACAGCAGTGGCCACCATCTGTAAACTCTGCCCT
Long Flanking Sequence:
GTATGCCATCAGAAAAGAAGGTTAGCAGTGCTGCAGATTGCCTGGCCTTCATGCAAGGTGGCTGCGAGCTAAAGAAGGTGCGACCCAACTCGCGCATCTACTCGCGATTCTACACTCTGGACACAGAACTGGGCTGCCTACGTTGGGAACCCTCCAAGAAAGATGGAGACCGAGCCCGACTTGATATATCTGCCATTCGTGAGGTCCGCACTGGGAAAAGCACAGAGACCTTCATCCATAATGGCCCATTAGATAACCTGGCTGAAGAAGCAGCCTTCTCTATCATTCATGGGGATGATTATCAGTCCCTTGACCTTGTTGCTCTTTCTGCCGATGTGGCCAACATCTGGGTGACAGGGATGCGGTACCTGTTGTCTCACCCTGGTGCCATTGGTGGAGGTATTGGAGGGGATGGGGGTGTGGGAGAAGGCAGCATTGGAAGCAAGATGAGGAGGAACTGGTTGGTGGCTGAGTTTGCTCTGGTTGATGAGGATGGACAC[G/T]GAATTGTGTCTGAAGATACAGCAGTGGCCACCATCTGTAAACTCTGCCCTGGCATTAAAGAAGCAAAGGTAACACGTTCTCTTATAATTAATTACATTAACCACAACAACTTGCATTTCATGAGTAAATATGCTCTGAAAGAGCCAAACAATACCGAATACAAAATTGGAAGCAACCTGAAATGCATATACTGTACATGTACTGCAGCAGTTTATGTAGAATCCTACGGTCTAAGAGCTGTGAGAAATAGAAGCACTAGAAAACAACAGACACTACACTACACTACAAAACAAGACAGCCATAAATGTGAGCAGAGGCTATATGATAATTTAAATGGCTGTTGCAGAGCTGTCTCTTTTTATTTTTGCTTAACTTGACTGGTTAGCCAGCCGTGCTGAGGTGCACAGCAATAGTTGCCTTGTAAATTTGGCAGCTGTGACAGTAGTTCCATGTGTGTATGTTTGTGTGTGGACTGGACAGCTGGGGACAGAAGGAGGACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21517
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000097475 Essential Splice Site 266 1137 2 8
ENSDART00000136894 None None 464 None 6
ENSDART00000144608 Essential Splice Site 274 578 2 3
Genomic Location (Zv9):
Chromosome 9 (position 33466091)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 32622037
GRCz11 9 32432783
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCAGTGGCCACCATCTGTAAACTCTGCCCTGGCATTAAAGAAGCAAAGG[T/C]AACACGTTCTCTTATAATTAATTACATTAACCACAACAACTTGCATTTCA
Long Flanking Sequence:
AAAGAAGGTGCGACCCAACTCGCGCATCTACTCGCGATTCTACACTCTGGACACAGAACTGGGCTGCCTACGTTGGGAACCCTCCAAGAAAGATGGAGACCGAGCCCGACTTGATATATCTGCCATTCGTGAGGTCCGCACTGGGAAAAGCACAGAGACCTTCATCCATAATGGCCCATTAGATAACCTGGCTGAAGAAGCAGCCTTCTCTATCATTCATGGGGATGATTATCAGTCCCTTGACCTTGTTGCTCTTTCTGCCGATGTGGCCAACATCTGGGTGACAGGGATGCGGTACCTGTTGTCTCACCCTGGTGCCATTGGTGGAGGTATTGGAGGGGATGGGGGTGTGGGAGAAGGCAGCATTGGAAGCAAGATGAGGAGGAACTGGTTGGTGGCTGAGTTTGCTCTGGTTGATGAGGATGGACACGGAATTGTGTCTGAAGATACAGCAGTGGCCACCATCTGTAAACTCTGCCCTGGCATTAAAGAAGCAAAGG[T/C]AACACGTTCTCTTATAATTAATTACATTAACCACAACAACTTGCATTTCATGAGTAAATATGCTCTGAAAGAGCCAAACAATACCGAATACAAAATTGGAAGCAACCTGAAATGCATATACTGTACATGTACTGCAGCAGTTTATGTAGAATCCTACGGTCTAAGAGCTGTGAGAAATAGAAGCACTAGAAAACAACAGACACTACACTACACTACAAAACAAGACAGCCATAAATGTGAGCAGAGGCTATATGATAATTTAAATGGCTGTTGCAGAGCTGTCTCTTTTTATTTTTGCTTAACTTGACTGGTTAGCCAGCCGTGCTGAGGTGCACAGCAATAGTTGCCTTGTAAATTTGGCAGCTGTGACAGTAGTTCCATGTGTGTATGTTTGTGTGTGGACTGGACAGCTGGGGACAGAAGGAGGACAGAAAGAAGCCACAGGGCCAAGTCTACACGTCTTTGTGACAGCGAGTGTGAGGCATCTGCTTCATGTGTGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41457
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000097475 Nonsense 384 1137 3 8
ENSDART00000136894 None None 464 None 6
ENSDART00000144608 Nonsense 392 578 3 3
Genomic Location (Zv9):
Chromosome 9 (position 33467496)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 32623442
GRCz11 9 32434188
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTACAGTCAGCTGAGTGCCAGTTATTAGACCCGGAGCACCAGAATGTGTG[C/A]CAGGACATGAAGATGCCCCTGTCTCATTATTTTATCAGTGCCTCCTACCG
Long Flanking Sequence:
TTGTATATCTAGTAATAGAACAGTAGTCATAGTTTTTTATTAATTATTTGCACATAACAATTCAAAACAACAAAGGTTGGATCACTTTTACAAAGTTTAATCAATAAAAGTGTTGCCATTACTGATATTTTTCTGCCTTTCACTCAGGTGCGTTTGCGCTTCAAGGAAATTCAGAGGAGCAAAGAGAAGCTTACTTCCCATGTTACGCTGGAAGAGTTCCAGGAGGCCTACTGTGAGCTGTGTACACGACCTGATGTCTATTTTTTGCTAGTGCAACTCTCTAAAGACCGAGAGTGCCTTGACGCCCAGGACCTGCGCCTTTTCCTGGAGTCAGAACAAGGTCTGTCAATGGCCACCACTGAAGGCTGCTTGGAGCTTCTTCGCCTCTTTGAGCCCTCTGCAGCTGGACGTGAGCGAGGTCTTTTGGGCTTGGATGGCTTTGCTCGCTACCTACAGTCAGCTGAGTGCCAGTTATTAGACCCGGAGCACCAGAATGTGTG[C/A]CAGGACATGAAGATGCCCCTGTCTCATTATTTTATCAGTGCCTCCTACCGCTCCTACCTGCTGGATGACCAAGTGCATGGCCGGGCTGATCTTGGGGGTCTCACTCGAGCCCTGCAGGCTGGCTGTCGTTGTCTAGAATTGGGGGTTACGGATGGGCCAGAAGGAGAGCCACTGTTGGGTGTAGACCATGGTGCAGAAGTAAAGCATCATCACCACCACCACCATCACCACCACCACCATCATGGTTCTGTTACTCTGCGCAGTGCCCTGGAAGTAGTCAATAAGTATGCTTTTCTCACCTCACAGTATCCTTTGTTGCTGTATCTGTGTCAGCGTTGTTCACCTTCCCAGCAACGTACTCTTGCACAACACTTAAAAAAAGTTTTTGGACCCAAGCTCTATACCCCTGAGTCTCTGCCTGTTAGTTTGGGAGGTCGTGCGACTACCTTGCCATCTCCAGAACAACTGAAGGGCAAGGTGCTTCTTGTTGGAAAGAAGCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34681
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000097475 Nonsense 539 1137 3 8
ENSDART00000136894 None None 464 None 6
ENSDART00000144608 Nonsense 547 578 3 3
Genomic Location (Zv9):
Chromosome 9 (position 33467959)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 32623905
GRCz11 9 32434651
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTCTGCCTGTTAGTTTGGGAGGTCGTGCGACTACCTTGCCATCTCCAGAA[C/T]AACTGAAGGGCAAGGTGCTTCTTGTTGGAAAGAAGCTTCCCCCAGAGGAG
Long Flanking Sequence:
AGTGCCAGTTATTAGACCCGGAGCACCAGAATGTGTGCCAGGACATGAAGATGCCCCTGTCTCATTATTTTATCAGTGCCTCCTACCGCTCCTACCTGCTGGATGACCAAGTGCATGGCCGGGCTGATCTTGGGGGTCTCACTCGAGCCCTGCAGGCTGGCTGTCGTTGTCTAGAATTGGGGGTTACGGATGGGCCAGAAGGAGAGCCACTGTTGGGTGTAGACCATGGTGCAGAAGTAAAGCATCATCACCACCACCACCATCACCACCACCACCATCATGGTTCTGTTACTCTGCGCAGTGCCCTGGAAGTAGTCAATAAGTATGCTTTTCTCACCTCACAGTATCCTTTGTTGCTGTATCTGTGTCAGCGTTGTTCACCTTCCCAGCAACGTACTCTTGCACAACACTTAAAAAAAGTTTTTGGACCCAAGCTCTATACCCCTGAGTCTCTGCCTGTTAGTTTGGGAGGTCGTGCGACTACCTTGCCATCTCCAGAA[C/T]AACTGAAGGGCAAGGTGCTTCTTGTTGGAAAGAAGCTTCCCCCAGAGGAGGAAGGTTCGGAAGGAGAGGTTTCCGAGGAGGATGAGGAAATTGGCGGTGGTGGTCCTTTAGCTGGCCGAAGGATGACTATACCTGGGGAAGAGGAATTGGGGGTGGTCCTTGTTGTCCCACCACCCCCACAGCCAAGGCGCCTCCGCTTGCGTCATGAATTGTCTGATCTTGTTGCAGTTGCTCGTACTGGAAGTCGAAACTTTTATGCTCATCGGGCAAGTATTCTGCCATCCCAACAACATTCACCCCCATCAACTCCTTCTACGCCAGGTACACCTTTGAACATTGATCCCTCCTACTGGACCCTATGCTCTCTTGGGGAAGGGGAGGCAGGAAGGCTGGCTAGTGAGAGTCCAGAGGAGCTGGTAAGCTTTACCAAACGCAATCTAACCCGTGTGAGGCCCAGCTCAGTCAGACTTGACTCTAGCAACCCAAACCCACAAGGCTAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2490
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000097475 Essential Splice Site 1045 1137 6 8
ENSDART00000136894 Essential Splice Site 392 464 4 6
ENSDART00000144608 None None 578 None 3
Genomic Location (Zv9):
Chromosome 9 (position 33484397)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 32640343
GRCz11 9 32451089
KASP Assay ID:
554-2762.1 (used for ordering genotyping assays)
KASP Sequence:
TGAAAATGCAGATGGAGTGCAGGAGAAAATCGCTCAAGTGCAAAAAGAAG[G/A]TAAGTGGAGGAGAAGATGAGAGCAGGATGAATTTCTTCCYATCTAATGAT
Long Flanking Sequence:
AGAAAAAAATATAGCTTAAAGGGGCTAATAATTTTGTCCCTAAAATAGTTTTAAAAAATTAAAAACGGCTTTTATTCTAGCCGAAATAAAACAAATAAGACTTTATCCAGAAGAAAAAATATTATCAGACATACTGTAAAAATTTCCTTGCTCTGTTAAACATCATTTGGGAAATATTTAAATAAAACATTTGAAGGGGTATATACATCTGAATATACACACACACACACACACACATATACATTGCATTTTTAATTTTATTTTAGTTCATTTTAAATATAGTTATACTATAGCAATGTAAAATTAATTACTGTCACTTTTGATCAATTGAATGCATCCTTGCTGAATAACTCTATCAATTTCATTCAGAATTGTTAAATATTTGATCAGTTAATAATGCAATTCCTGTCTGATGCGTCCTCAGATGATCTCCGCTAACAAACAGCTGATTGAAAATGCAGATGGAGTGCAGGAGAAAATCGCTCAAGTGCAAAAAGAAG[G/A]TAAGTGGAGGAGAAGATGAGAGCAGGATGAATTTCTTCCCATCTAATGATGCTACAGTTAATGCCCCTGCAGATGCATGAAAATCTTAATAAACGGTTCACAGGTTTCTCAAAATTACATTCAAATAGTATAGCGTTATCCCAACACACACAGTCCTGTCAACACTCTCGAATATTGCAAACACATACTGAAGGGTGTTGAAAATACCTTCAAAGTTGTTTTAAAATGATGTGTTAATGTTGATGATTTAGTAAATAGGAACACTGTTTAGTTGGAATTCATTACTTCATCTTTTATCCCACTAGTCCTGCGGTACAGTGATACTTTCAAAAATAGTGAAGCTTTTCCAGTAACAAGCTACAAGCAATTTTTTTTTTTTTACAAAAGCACATTTGTTTTTGTAGCATTTCAGACTACAACAGCATGGTTATGTCAATATGTACTGCCCGTGCTACTTCGTTAGTCGACACAGTATTCAAAGAATGTAACCTTGGGATGTT
Associated Phenotype:
Not determined