Busch Lab

ZMP

itm2bb

Ensembl ID:
ENSDARG00000041505
ZFIN ID:
ZDB-GENE-040426-2139
Description:
integral membrane protein 2Bb [Source:RefSeq peptide;Acc:NP_998141]
Human Orthologue:
ITM2B
Human Description:
integral membrane protein 2B [Source:HGNC Symbol;Acc:6174]
Mouse Orthologue:
Itm2b
Mouse Description:
integral membrane protein 2B Gene [Source:MGI Symbol;Acc:MGI:1309517]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa13204 Nonsense Available for shipment Available now
sa41427 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa34652 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa13204
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000101470 Nonsense 85 254 3 6

The following transcripts of ENSDARG00000041505 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 26370790)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 25526576
GRCz11 9 25337445
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CAGAGGGAYCAGGTGTTTATCTGTGGGCTGAAGYACTACGAGGAAGACTA[T/A]GAGCTGAATGAAGAGGTGGACCYAGAAATTGGAGCACCGCTGAGGCTGAT
Long Flanking Sequence:
GTGGGAGAAATCGGAGCATTCTTTAGGAAACCCACGTGAACACGGGAAGAACATGCACACAGAAATGCCAACTGACCCAGTTAGGACTCGAACAAGTGACATTCTTGCTGTAAGGCGACAGTGCTAACCACTGAGCCACCGTTTCGCCCCCTTTAACATTAATTCCTTAACCCAAAATAAAAATCATAATATTGTGCATATCATCATTAATTCTCATTAAAAAGGGTTCAAATTTGCATCTGCCAGTGTCAAAGTTTCTTCTGTTAAGTGTAATCCTAAATATTTCAACAGTATATAGTGAGAAAGCCCATTATCTGGATGAAATTAGTAGGATGATACTTGATGTTTGTTTTCTATCAGAGATTTATTAGGAGATATGAAAATAAATCAAAATTGTTAGATACATTATAGCTACTTTTTTCTTTTTTGTGTACAATCCACAAAACTGAACAGAGGGACCAGGTGTTTATCTGTGGGCTGAAGTACTACGAGGAAGACTA[T/A]GAGCTGAATGAAGAGGTGGACCCAGAAATTGGAGCACCGCTGAGGCTGATTGAGGAGAATGTCAGCTTTTTTGAAGATGATGAGGTGGAGCTCATCAGTGTACCAGTGCCAGAGTTCAAAGACAGCGATCCAGCTGGCATCCTGCACGACTTCACCATGGTATACCAAATATACAAAGTTACACACACATATATTTGTACAGCTAATCTTTTTTGGGACTTCGATTGTTTTTATATATAGCAAAAAGTGTTTTTTATTCTTTAAACTAGAGCAAAAATTAACCCTCATAGAAATTGTTCTGCATTTTTAGATTTACAATTTTTCTATTTATTTAACACTTTATTTATGTTGTTAAGACATTGTCCTTACACCATAATTTTAAGTAGAGCATACACACACATAGTGTTAGCCTATGGAAATTTATTGTTTGTGGCACCTTGAAGTTTTGGTTTATTTCTGGAAAGACATTATGACATTAGCTAATCAAAATTAATTAATCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41427
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000101470 Essential Splice Site 175 254 4 6

The following transcripts of ENSDARG00000041505 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 26374476)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 25530262
GRCz11 9 25341131
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGTTGTAATGCCACCAAGAGACTTTCAGGAGTTCCTGGTCAACATCAAG[G/A]TAAGCATCCAGAATAAAAGTCAGTGAGGGATTCTCGTGTCTTTTTTCACA
Long Flanking Sequence:
CGTCGGGGAAGACGGTAGGGGATACAAGCGTGCTTTGGCCCGGTTCGAGGCAACTGTACCTAGTGTGAGTACGGCCTTAAATGTAGGTTTGGAATAAATTACATTTAAAAATGATATTCAAACAGAAAACAGTAATCACATTTTTAACATTTGTCTAAATATGACAAATACTATTTATACAAACACAATGATTACATTGGAGTTTCACAGCAAAAAAGATACAAATATCATCAAAAGTTTGTTTTAAATGAGAAAAATCCAACGAAATGCTTCTATTTTTTAGTCTACAATCAGTTATATAAATAATTTGAATCATTTAATTAATATTTAGTAGTGTCTGTAATTATATATGTAAAATGATGCCTGAAGAAGTTGTGTGTGAATTTCAGAAACTGACTGCTTATCTCGACCTGAATCTGGACAAATGCTACATCATCACTCTCAACACCTCAGTTGTAATGCCACCAAGAGACTTTCAGGAGTTCCTGGTCAACATCAAG[G/A]TAAGCATCCAGAATAAAAGTCAGTGAGGGATTCTCGTGTCTTTTTTCACACTAAATGAATTTTGTGTGTGTGTGTGTTTTTGCAGGAAGGAATGTATCTTCCTCAGACATACCTGATCCATGAGGAGATGATGGTGACAGAGAAGCTGGACGACACCAGTGATCTGGGCTATTACATCAATAACCTGTGCAAAGACAAAGACACGTACAGACTGCAGCGCAGAGACACCATTCTGGGTGAGAGACTACAAACCAACACTTAATTAGACTGTATACAACAAACAGTGTGTATGTTTTTCCATAAACACAGTCCTCCACTAATATTGGCTTGATGAATATCAGCCAGGGAGAATCTCTTATTTTAGTTCAACTGTCATATTAACAAAGAAAATGCTTTCATTGAGCATTTGCACACACAATACAGTTTGAAAATAATATATGTGTTAAATATATGTGTTAATTCAAGTGAGCAAAGTGTATTTCCCCCTGGAAGACTTTTGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34652
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000101470 Essential Splice Site 176 254 5 6

The following transcripts of ENSDARG00000041505 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 26374561)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 25530347
GRCz11 9 25341216
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGTGTCTTTTTTCACACTAAATGAATTTTGTGTGTGTGTGTGTTTTTGCA[G/A]GAAGGAATGTATCTTCCTCAGACATACCTGATCCATGAGGAGATGATGGT
Long Flanking Sequence:
GGTTTGGAATAAATTACATTTAAAAATGATATTCAAACAGAAAACAGTAATCACATTTTTAACATTTGTCTAAATATGACAAATACTATTTATACAAACACAATGATTACATTGGAGTTTCACAGCAAAAAAGATACAAATATCATCAAAAGTTTGTTTTAAATGAGAAAAATCCAACGAAATGCTTCTATTTTTTAGTCTACAATCAGTTATATAAATAATTTGAATCATTTAATTAATATTTAGTAGTGTCTGTAATTATATATGTAAAATGATGCCTGAAGAAGTTGTGTGTGAATTTCAGAAACTGACTGCTTATCTCGACCTGAATCTGGACAAATGCTACATCATCACTCTCAACACCTCAGTTGTAATGCCACCAAGAGACTTTCAGGAGTTCCTGGTCAACATCAAGGTAAGCATCCAGAATAAAAGTCAGTGAGGGATTCTCGTGTCTTTTTTCACACTAAATGAATTTTGTGTGTGTGTGTGTTTTTGCA[G/A]GAAGGAATGTATCTTCCTCAGACATACCTGATCCATGAGGAGATGATGGTGACAGAGAAGCTGGACGACACCAGTGATCTGGGCTATTACATCAATAACCTGTGCAAAGACAAAGACACGTACAGACTGCAGCGCAGAGACACCATTCTGGGTGAGAGACTACAAACCAACACTTAATTAGACTGTATACAACAAACAGTGTGTATGTTTTTCCATAAACACAGTCCTCCACTAATATTGGCTTGATGAATATCAGCCAGGGAGAATCTCTTATTTTAGTTCAACTGTCATATTAACAAAGAAAATGCTTTCATTGAGCATTTGCACACACAATACAGTTTGAAAATAATATATGTGTTAAATATATGTGTTAATTCAAGTGAGCAAAGTGTATTTCCCCCTGGAAGACTTTTGAAAAGAAAATTGTTCCACATAACTTCCTCTTTTACAGAGTGATGTAAACATAAGGGCTGCGGTTCACTCCACTTTTAGACATGCAC
Associated Phenotype:
Not determined