si:ch211-173o4.2

Ensembl ID:

ENSDARG00000078864

ZFIN ID:

ZDB-GENE-081105-61

Description:

si:ch211-173o4.2 isoform 2 [Source:RefSeq peptide;Acc:NP_001121728]

Human Orthologues:

CIT, LATS2

Human Descriptions:

LATS, large tumor suppressor, homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:6515]
citron (rho-interacting, serine/threonine kinase 21) [Source:HGNC Symbol;Acc:1985]

Mouse Orthologues:

Cit, Lats2

Mouse Descriptions:

citron Gene [Source:MGI Symbol;Acc:MGI:105313]
large tumor suppressor 2 Gene [Source:MGI Symbol;Acc:MGI:1354386]

Allele Name	Consequence	Status	Availability
sa38734	Nonsense	Mutation detected in F1 DNA	Not yet available
sa7627	Missense	Mutation detected in F1 DNA	Not yet available
sa38735	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa34612	Essential Splice Site	Available for shipment	Available now

Allele Name:

sa38734

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000110996	None	None	1078	None	10
ENSDART00000111899	Nonsense	286	1140	5	9
ENSDART00000113352	Nonsense	286	1140	3	7
ENSDART00000139620	Nonsense	286	1140	5	9

Genomic Location (Zv9):

Chromosome 9 (position 22329427)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	9	21485213
GRCz11	9	21296082

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AAGGATACCCTAGTGGGATTGACCAGGCCATGATGGGGTACAGTGTGTCT[G/T]GACCACCCATGCAAATCCAGTCTCAGCCCTCAGGAGGGCCTGGAGCACAT

Long Flanking Sequence:

CCTCACACTGAACAGATTGTACGTGTCATCAAACAGACTTCCCCAGGCAAGACAATACTAAAGCACACTCACTATACCTATGATATGACTTGAATTATGTTCTGTATTTGAACCTATTAATATTTCCTATAGGAAAAAGTGGCATGCCAAATTTGATGGACCACAGGACAGCAATGGAAGGCAGTGGGGATGGTGCACTTCCCCCTTATCATCAAATGGGAGCACCATTGTATGAGGGAGCTAGTTATGGGGCTGAGGGTGAAATGGCTCGGGCATACATGGGTGGACCACCTGTCATGAACTACATGCCACCGCCTGCCAACCCTTCACAGGGTGCTACCATGGGAAACCCGATGGGACGCCCTGCAAGTATGGGTGCTTACTCCACAAACATGGCTCCTCAAAATAATACTGGGAATCCAATGTACACCCCTGGTCCAGCCCAGCAAAAAGGATACCCTAGTGGGATTGACCAGGCCATGATGGGGTACAGTGTGTCT[G/T]GACCACCCATGCAAATCCAGTCTCAGCCCTCAGGAGGGCCTGGAGCACATTATGACTACAGGTCGCATATGATGGAGAATTCCAGCTACGGGGTCAAAAGAAGTGCTTCCTTTCAGAATAAGATGCCCCAACTAACTACAGAAAATTATGTCAATATGCCAAGCAAAGCAGCAATGGGCCAAAATGCTGGTGGCTATGCTCCCAACTTATATCTGCCACCACATTCACATCCACGCCAAGCTAGCCCCACCTCACACCAGGTTCACATGATGCAGCGCCCCCCAGGTGTTGCCCCTGGAGCTATGGGTGGGGAGTTCTCTGATGTTCCTCAAGGCCTTCTCACCCCTTCCAGGGCCAGTTTAAATCTTGACCTGTATGAGCATCACTGGCCAGGAGCTCAAGGTCCTGAGGGGACTCCTCCAGCCAGGCAGCCACAAGGGCCCTTCAGAGGGGAGGTACGCGTCCCCAGTCGGACCAATTCTTTCAACAACCACCAAAAG

Associated Phenotype:

Not determined

Allele Name:

sa7627

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Missense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000110996	Missense	584	1078	6	10
ENSDART00000111899	Missense	646	1140	5	9
ENSDART00000113352	Missense	646	1140	3	7
ENSDART00000139620	Missense	646	1140	5	9

Genomic Location (Zv9):

Chromosome 9 (position 22330508)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	9	21486294
GRCz11	9	21297163

KASP Assay ID:

554-4070.1 (used for ordering genotyping assays)

KASP Sequence:

GAGGGAGTCTCGTATTAAGAGTTATTCTCCATTTGCCTTTAAGTTCTACA[T/A]GGAGCAACATGTGGAGAATGTGATGAAGACATACCAGCAGAAACTTAATC

Long Flanking Sequence:

AACTGCAGTGACCTCTCCACCAATTCAGCCACCTGTTAAGAGTATACGGGTCATGAGGCCTGAGCCGAAGACAGCAGTGGGACCATGCCATCCAGGGTGGCTGAGTGCACAATCCCCGGAAGCACAGGATTCTCTTGGATACATCCCAGATGAGAATTTTACCCTGGAACCCAGTCAAGAACATCGATGCCCACCTCCACCTTACCCCAAAACACTGCTTGTGTCTGGATCTGGACCTGAGCCTGCATCCTTAGAGCCTGTAGCCATGAGTGGACTTCAAGATGTCAGTGCCACAGGTAGGACTATCCAGAGTTCCTCGGTAGGAAAGCAGGAGGAATCCATCTTCAAAGACAAAGTGAAAATGGGCAAAGGAGAAAAGGCTGTGAAGGATAAGAAGCAGATCCAGACATCACCTGTGCCTGTACGAAAAAATGCCCGTGATGAAGAGAAGAGGGAGTCTCGTATTAAGAGTTATTCTCCATTTGCCTTTAAGTTCTACA[T/A]GGAGCAACATGTGGAGAATGTGATGAAGACATACCAGCAGAAACTTAATCGCAGAATGCAGCTGGAGCAAGAGATGTCCAAGGTAAGCTATGCTGGAACTGTTTATCACAAAGAACACCGTTTACTTTATAATTTGTATAATTGAGTTGTTAACTCTTTGAGTTATCCATAAAAGGGTATATTTTTTGTTTGTTTTCAACTGAGTCCCCTCTAACAATCTCTTTCATTATTTTAGGCTGGCCTTTCAGAGGCTGAGCAGGAACAGATGAGAAAGATGCTTTACCAGAAGGAATCCAATTACAATCGACTACGACGTGCCAAGATGGACAAATCAATGTTTGTCAAAATCAAGACACTCGGCATTGGGGCCTTTGGTGAGGTGTGTCTAACCCGAAAAGTAGACACAGGAGCCTTGTATGCAATGAAGACTTTGCGAAAGAAAGACGTTCTTAACCGAAATCAAGTAGCCCATGTTAAAGCTGAACGGGACATTTTAGCAG

Associated Phenotype:

Not determined

Allele Name:

sa38735

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > T

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000110996	Essential Splice Site	611	1078	6	10
ENSDART00000111899	Essential Splice Site	673	1140	5	9
ENSDART00000113352	Essential Splice Site	673	1140	3	7
ENSDART00000139620	Essential Splice Site	673	1140	5	9

Genomic Location (Zv9):

Chromosome 9 (position 22330591)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	9	21486377
GRCz11	9	21297246

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

ACCAGCAGAAACTTAATCGCAGAATGCAGCTGGAGCAAGAGATGTCCAAG[G/T]TAAGCTATGCTGGAACTGTTTATCACAAAGAACACCGTTTACTTTATAAT

Long Flanking Sequence:

CATGCCATCCAGGGTGGCTGAGTGCACAATCCCCGGAAGCACAGGATTCTCTTGGATACATCCCAGATGAGAATTTTACCCTGGAACCCAGTCAAGAACATCGATGCCCACCTCCACCTTACCCCAAAACACTGCTTGTGTCTGGATCTGGACCTGAGCCTGCATCCTTAGAGCCTGTAGCCATGAGTGGACTTCAAGATGTCAGTGCCACAGGTAGGACTATCCAGAGTTCCTCGGTAGGAAAGCAGGAGGAATCCATCTTCAAAGACAAAGTGAAAATGGGCAAAGGAGAAAAGGCTGTGAAGGATAAGAAGCAGATCCAGACATCACCTGTGCCTGTACGAAAAAATGCCCGTGATGAAGAGAAGAGGGAGTCTCGTATTAAGAGTTATTCTCCATTTGCCTTTAAGTTCTACATGGAGCAACATGTGGAGAATGTGATGAAGACATACCAGCAGAAACTTAATCGCAGAATGCAGCTGGAGCAAGAGATGTCCAAG[G/T]TAAGCTATGCTGGAACTGTTTATCACAAAGAACACCGTTTACTTTATAATTTGTATAATTGAGTTGTTAACTCTTTGAGTTATCCATAAAAGGGTATATTTTTTGTTTGTTTTCAACTGAGTCCCCTCTAACAATCTCTTTCATTATTTTAGGCTGGCCTTTCAGAGGCTGAGCAGGAACAGATGAGAAAGATGCTTTACCAGAAGGAATCCAATTACAATCGACTACGACGTGCCAAGATGGACAAATCAATGTTTGTCAAAATCAAGACACTCGGCATTGGGGCCTTTGGTGAGGTGTGTCTAACCCGAAAAGTAGACACAGGAGCCTTGTATGCAATGAAGACTTTGCGAAAGAAAGACGTTCTTAACCGAAATCAAGTAGCCCATGTTAAAGCTGAACGGGACATTTTAGCAGAGGCTGACAATGAGTGGGTAGTCAGGTTGTACTATTCATTTCAAGACCGAGACAATCTGTATTTTGTCATGGATTACATTCCT

Associated Phenotype:

Not determined

Allele Name:

sa34612

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000110996	Essential Splice Site	866	1078	8	10
ENSDART00000111899	Essential Splice Site	928	1140	7	9
ENSDART00000113352	Essential Splice Site	928	1140	5	7
ENSDART00000139620	Essential Splice Site	928	1140	7	9

Genomic Location (Zv9):

Chromosome 9 (position 22331616)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	9	21487402
GRCz11	9	21298271

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TTTGGTGGGCACCCCTAACTACATTGCCCCTGAGGTGCTTTTGCGCAAAG[G/A]TAAGAATATTCACATAGTCACTCGGAAGTACAAGGACATTACAAAGAATT

Long Flanking Sequence:

ATCCGTATGGGAGTTTTTCCAGAGGTCTTAGCCAGGTTTTATGTGGCAGAACTGACACTGGCAATTGAGAGTGTGCATAAGATGGGTTTCATCCACAGAGATATCAAGCCAGACAATATCCTCATTGACCTGGATGGACACATCAAACTGACTGATTTTGGTCTATGTACGGGGTTCCGATGGACTCACAACTCAAAGTATTACCAAAAAGGTAAGAGAAGGTGATGCTTATAGCCTTTAAAAAGTCCTTAATGCTGTTGCAGTGTTTATTAAATCCAATGAATTGGTTGCCTTCTCTCTTTGCACTGCTTGAATAGGGAACCATATCCGACAGGATAGCATGGAGCCAAGTGACTTTTGGGATGATGTGTCTAATTGCCGTTGTGGTGACCGGCTGATGACTTTGGAACAGAGAGCAACTCGACAACACCAGCGCTGCCTGGCGCATTCTTTGGTGGGCACCCCTAACTACATTGCCCCTGAGGTGCTTTTGCGCAAAG[G/A]TAAGAATATTCACATAGTCACTCGGAAGTACAAGGACATTACAAAGAATTGCTAGTGCCTATAGAACCTTTTTCTTTTTAATTGCTCCTTTTAATTAATTTTAATACACAGGATACACACAGCTGTGCGACTGGTGGAGTGTGGGAGTGATCCTGTTTGAGATGCTGGTTGGCCAACCACCCTTTCTTGCTCCAACCCCAACAGAGACGCAGCTTAAGGTAAGAGTTCTGTATGCATGTTTTTAGTTGATCCTGCTCCTGGAGGGCAAGTATCATACAGAGTTCCAACCAACCCCAACATACTTGGAAATTTCTAGTAATCCTGAAAACTTGAATAGGTGATTCAATTAGGCAAGACAGTGCCCATGCAGGAAAAAGGACTGCACATCTTTGTTTTCTTTAAATAATATTTTATAATATTTGAGGTTAAGAGTTTTGATGACAAGAAATAAACTTTTGTTGATGTCACTACCTCTACAGGTGATAAACTGGGAGAACACT

Associated Phenotype:

Not determined

ZMP

Alleles

Mutation Details

Mutation Details

Mutation Details

Mutation Details