Busch Lab

ZMP

fstl1b

Ensembl ID:
ENSDARG00000039576
ZFIN ID:
ZDB-GENE-030131-3029
Description:
follistatin-like 1b [Source:RefSeq peptide;Acc:NP_001034710]
Human Orthologue:
FSTL1
Human Description:
follistatin-like 1 [Source:HGNC Symbol;Acc:3972]
Mouse Orthologue:
Fstl1
Mouse Description:
follistatin-like 1 Gene [Source:MGI Symbol;Acc:MGI:102793]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa34567 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa21439 Nonsense Available for shipment Available now
sa44701 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa1267 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa34567
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000083326 Essential Splice Site 19 309 2 11
ENSDART00000121456 Essential Splice Site 20 310 2 11

The following transcripts of ENSDARG00000039576 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 10063268)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 9863819
GRCz11 9 9841856
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGTGTTTACCCGTGTTTTTCCTCCTGGCTGTAGTCTGCTGTCATGCCGAG[G/A]TAAGTTACACCAAACCCGCTTTTAATAAGGAGAAGAGCTCGTGTTTTTGG
Long Flanking Sequence:
TTTTCTAACATTCCACTAATATTTGTTATGTCTCACACTAGCAAAAGCTGCAATTTTCTGCAAGTGTAGGCTAATATATGCACTAATATGGACTTATTGGTCTCGCAAACCTCTAGCACTTTTATCCGAGCTTGTGCTCATTATCTGGATCTGCTCCACGGCTTTTCACGGGCCACGTCACGTCACGGAGGGGGAAGAAACGGATTCCTGAGCGCTGCTCGAGTTTCCTGCGATCACATCCTCAGACCTACAGCGGACCGAGACGTCGCGCTTTTCCTCCTCACAGACACCCAGGCGGCGTTTTTTTGCAAAAAATGGTGAGAAACCTGAATTATATTTACAACATTTTACAGCGTCAAAACAACTTGTGTCGTTTTGCCTTGCGTTTTCTCCTTTTGTAATGTCTTTTCCTCCGTTCTCCCTCTTCTCTCTGCCCGTTACAGATGTTTCGGTGTTTACCCGTGTTTTTCCTCCTGGCTGTAGTCTGCTGTCATGCCGAG[G/A]TAAGTTACACCAAACCCGCTTTTAATAAGGAGAAGAGCTCGTGTTTTTGGAAAAGAATGTTTATTGTGGATCCTGATAATAGTTTCTCTGATATCCGACTTGGCCAGAATGAACTGTTGAAGAAATGAGTGCACTAACTAACTAACATTACTTACAACAAAACAATGGATAATTATGATTAATGTTAAAACTGCGGCCAGTGTTGTTGTTTTTCCCAATTGAAAATGTTTTGTACATAAAGAAAAGCAACTTCAATGAGGTTGACTAACATTAGATCATTCCAGACGCCTTCGAGGAAAAAATAGAGAGGGGGAGAGACAAAAAAAGGTTTATTTTACATGCATAGAGCGGGTCGCACCTCATGTTGATATCACATGATCATGTGTGCACGTGACCGAATTGGCACTTAAACTAATATGCATATTTTACTTTAAAATTAGTATCAAGTCAGAAAGCATTTATGCATTCTGATAGAGAGCTCAGTATAATATGAAACTTAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21439
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000083326 Nonsense 56 309 4 11
ENSDART00000121456 Nonsense 57 310 4 11

The following transcripts of ENSDARG00000039576 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 9992835)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 9793386
GRCz11 9 9771423
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTAATGTGGCAGTGGTGATGTTTTCATTGTTGTGTTCTCCTGCAGCAATG[C/A]AAGACTCATAAGCGCTCGGTGTGTGGCAGTAATGGAAAGACATACCGGAA
Long Flanking Sequence:
ATGTCAACAGAGCAGAGATCAAAGTCTCATAATGCAATTTACAACAATAAATAAACTGAAAATACTTGTGAATCACAACATACAGAAACTGTTAATGAACAGATATTTATGTACCGTGTATCATCATGCCAGGTCTGATGCTATATTATTAGGATTATTTATCTCAAAATTATAGTCTCATAAACTTTTGCTCAATAACAGTACTGTATGTGTGGGATTGGGGTCATGTGTGATGTATAGACTTTGCTATGTGTCTACACAGCTCAGCAGATTATACAATCATACTATTGTGGTACCACCAGCCTGCTCTCCATACTTATATTTTATTACAGGCTTAGTGTCAGCTTTAAAGCAGAGGAAAATTAAATTAGAGTCACAGTGTCACAGAGCATTTAAACACCAGCCTTTGTTTATTTCATGCATTTTATTGTTGTTTGCAAGATAGATATTGTAATGTGGCAGTGGTGATGTTTTCATTGTTGTGTTCTCCTGCAGCAATG[C/A]AAGACTCATAAGCGCTCGGTGTGTGGCAGTAATGGAAAGACATACCGGAACCACTGCGAACTGCATCGTGATGCCTGTCTCACTGGACTGAAGATCCAAGTGGCTCATGATGGACACTGCAAAGGTGAGCATACAGAAGAACTTGAATCAGTAACAGCAGACTGATTAGGGATGATACAGACTAGAAATCAAATTTGCTGCTAATATAAAGTTCTATCATAAAACTCATTTGGGTGCACAGGATGATGGGTCCTATGCAATCTGCTTTCAACCACAGGAAGTGTGATGCAGGAGGACCTCAGCAGCCAATACGCTTGCTTCTCAACATTTACTGAACCACATCTCAGTGTTCCAATCTGCAGCACATTTACGGATACTCTTCTCCACCACAGCTCCAACTGTGTATTCAGTTTCAGTCTTCGCAGTTGCAATATTATAGTTAAATAAAATCGGCTATCAAAGTGGTCACTAGATAATGGCTTAAACTATATTGTAATGGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44701
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000083326 Essential Splice Site 98 309 None 11
ENSDART00000121456 Essential Splice Site 99 310 None 11

The following transcripts of ENSDARG00000039576 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 9992709)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 9793260
GRCz11 9 9771297
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTCTCACTGGACTGAAGATCCAAGTGGCTCATGATGGACACTGCAAAGG[T/C]GAGCATACAGAAGAACTTGAATCAGTAACAGCAGACTGATTAGGGATGAT
Long Flanking Sequence:
TGCCAGGTCTGATGCTATATTATTAGGATTATTTATCTCAAAATTATAGTCTCATAAACTTTTGCTCAATAACAGTACTGTATGTGTGGGATTGGGGTCATGTGTGATGTATAGACTTTGCTATGTGTCTACACAGCTCAGCAGATTATACAATCATACTATTGTGGTACCACCAGCCTGCTCTCCATACTTATATTTTATTACAGGCTTAGTGTCAGCTTTAAAGCAGAGGAAAATTAAATTAGAGTCACAGTGTCACAGAGCATTTAAACACCAGCCTTTGTTTATTTCATGCATTTTATTGTTGTTTGCAAGATAGATATTGTAATGTGGCAGTGGTGATGTTTTCATTGTTGTGTTCTCCTGCAGCAATGCAAGACTCATAAGCGCTCGGTGTGTGGCAGTAATGGAAAGACATACCGGAACCACTGCGAACTGCATCGTGATGCCTGTCTCACTGGACTGAAGATCCAAGTGGCTCATGATGGACACTGCAAAGG[T/C]GAGCATACAGAAGAACTTGAATCAGTAACAGCAGACTGATTAGGGATGATACAGACTAGAAATCAAATTTGCTGCTAATATAAAGTTCTATCATAAAACTCATTTGGGTGCACAGGATGATGGGTCCTATGCAATCTGCTTTCAACCACAGGAAGTGTGATGCAGGAGGACCTCAGCAGCCAATACGCTTGCTTCTCAACATTTACTGAACCACATCTCAGTGTTCCAATCTGCAGCACATTTACGGATACTCTTCTCCACCACAGCTCCAACTGTGTATTCAGTTTCAGTCTTCGCAGTTGCAATATTATAGTTAAATAAAATCGGCTATCAAAGTGGTCACTAGATAATGGCTTAAACTATATTGTAATGGTGCCATAGAATAAAAATCAGGATATACAGTACATAGGCAAAGCTGAGTGATAAGAGTACAGTACCTTGATTGAAATGACCATTGTTCCACTCCTTGTGAAAAACGGGCCAAAACACAGACTATTAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1267
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000083326 Essential Splice Site 266 309 9 11
ENSDART00000121456 Essential Splice Site 267 310 9 11

The following transcripts of ENSDARG00000039576 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 9964902)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 9765453
GRCz11 9 9743490
KASP Assay ID:
554-1182.1 (used for ordering genotyping assays)
KASP Sequence:
CTGCGTCTGCGCTTGTGGAAACTGGGTCTGCACCGCCATGACTTGTGATG[G/A]TGAGCTTTAATTTGCAMATCTGTTATCATCTTATTTTGATAAATGACAGG
Long Flanking Sequence:
GCAATTATGAAAATTAGCAGGGGTGGCCAAACTTTTGCATAAGACTGTACATCACATTTATACAATATACTGACAGCACACTTCAATCTTATTCATATGTTCTATCTTTCCCTTTGTAGCAACACAGTCATTCCAAAGTAATTTCCTGTTTTGTATTTGGGAATCTGGGACACAGGCTTATTCAGTTGCAGACTCAGCTGCATAAAAAAGCATGCACACAAAATGGCCTGTTTGGACGGCTTTTGTTGGTTTTAGCTTAGTTTATAGAGAAAAGCAGATCTCGTTTCGGCAGTCCTCTGTTAACTCATGTAAGAAAACTATGGCATATTTTTGGAGAACTAATTTTATTTTCCTGAGCATGGGTTAACATATGTTTTGTATCATTTCAGAGTGTGCTCTAGAAGATGAGACATATGAGGATGGTGCAGAGACGCAGGTGGAGTGCAATCGCTGCGTCTGCGCTTGTGGAAACTGGGTCTGCACCGCCATGACTTGTGATG[G/A]TGAGCTTTAATTTGCAAATCTGTTATCATCTTATTTTGATAAATGACAGGAGAGTGGCATAAAATAAGCACTTTGCTCTGGAAGTGTTAGGAGACTAAGATAAAAAAAAAGGTATATCTAATTATATTTCAGCATGTCAAGATATATTCAAAGTTCTATTCAGGCGGCATGGCGCCACACTGGTTAACACTGTCGCCTTACAGCAAGAAGGTTGCTGTTTCAAGTCCCGGCTGGTTCAGTTGGCATTTCTGTATGGAGTTTGCTTGTTCTTCCTGTGTTGGAGTGGGTTTCATCCGGGTGCTCCAGTTTCCCCCACAGTTCAAATACATTCTCTCTAGGTGAATTAGGAAAAAACTAAATTGACCATAGTGTATGATTGTGGGAGTGTATGGGTGTTTTCCAATACTGGGTTGCAGCTGGAAGGGCATCAGCTGTGTAAAACATATACCATAATAGTTGGCGGTGAAACCCCTGATAAATAAAGGGACTAAGCTGAAGGA
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037
whole organism
ZFA:0001094
quality
PATO:0000001
normal
PATO:0000461