Busch Lab

ZMP

brms1

Ensembl ID:
ENSDARG00000051955
ZFIN ID:
ZDB-GENE-030616-596
Description:
breast cancer metastasis-suppressor 1 [Source:RefSeq peptide;Acc:NP_956391]
Human Orthologue:
BRMS1
Human Description:
breast cancer metastasis suppressor 1 [Source:HGNC Symbol;Acc:17262]
Mouse Orthologue:
Brms1
Mouse Description:
breast cancer metastasis-suppressor 1 Gene [Source:MGI Symbol;Acc:MGI:2388804]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa34210 Nonsense Mutation detected in F1 DNA Not yet available
sa21110 Essential Splice Site, Missense Available for shipment Available now
sa31610 Essential Splice Site, Missense Available for shipment Available now
sa7095 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa34210
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000073673 Nonsense 177 265 6 7
ENSDART00000073675 Nonsense 177 271 6 10
ENSDART00000121545 Nonsense 177 271 6 10
ENSDART00000126714 Nonsense 153 314 6 11
Genomic Location (Zv9):
Chromosome 7 (position 60884210)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 60103175
GRCz11 7 60408412
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TATCGAGTCTGTAATAAGATGCTTGTTTCTGTAGAGTGAGAAAACCCTTT[T/A]GTTTGATGCCATGAAGACAGAACTTTTGGAGAAGATCCGCAGACTGGAGG
Long Flanking Sequence:
CCTTCTAGCTGCAAGCCAGTACTGGGAAACACCCATACCCACTTATTGACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACTCATACACTACGGCCAATTTAGTTTATCAATTCCCCTATAGTGCATGTGTTTGGACTGTAGGGGAAACCGTAGCACCCGGAGGAAACCCATGCTAACACGGGGAGAACTGGCCCAGCAGGGACTTGAACCAGTGACCTTCTTGCTGTCCACTGTACCTCCCATTTGAGTAATATTTCATTATGTCACATTAATTCACACTCAAACATGCACACATCACATTTATTACAATCTAGAAGCATTGCCACAGTCTCTGCCACAACAGTTGTGTTTGTGTGTTGACAGTGCAGTGATGACCCTAAATCATATCGAGTCTGTAATAAGATGCTTGTTTCTGTAGAGTGAGAAAACCCTTT[T/A]GTTTGATGCCATGAAGACAGAACTTTTGGAGAAGATCCGCAGACTGGAGGAGGACAAACAGAGCATAGACATCACCTCAGGTACATGCACACGAACACTCACACACCCACATACAAGACTGCCTGCTTATCTGAATCTGGAATCTATGATACTTTTTAATAAGATTTCTATATCTGTCTACATAATATAAAAATCTTAGTAAATTTACATACACTACCAGTCAAAAGTTTAGGATCAGTTTTTTTTCTTCTTCATGTTTTTTTAAAAGAAAATTATTTTGAAGGCAGCATTTATTAAATGTAAAATAATTGTTAAATATTTAAACAAATTTTAAATAGCTGTTTTCTTATATATAGATTCAAATGAAATTATTACTCCACACATTATTGCTTTTATTACTATTACCATTATTATTAATAATAATATTAATAATAATAATTACAATAATAATTAATGTTAGAGTGATTTCTGAAGGATCATGTGACATAGTCGTAATAAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21110
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site, Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000073673 Missense 226 265 7 7
ENSDART00000073675 Essential Splice Site 256 271 None 10
ENSDART00000121545 Essential Splice Site 256 271 None 10
ENSDART00000126714 Essential Splice Site 232 314 None 11
Genomic Location (Zv9):
Chromosome 7 (position 60887114)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 60106079
GRCz11 7 60411316
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TATGCTAAGAGAAACTGACATACTAGAGGACTGGACAGCCATCAAGAAGG[T/C]ATTAATTATGAGTTATCAACCCTTCACTCACTGTAAAAATGTTTTATGGA
Long Flanking Sequence:
TGTCATTTAGTATCTTTCACAGACAGCTTTTTTATCTTGCAAAATAAATGTTTTAAATATTCATCTTATTTGTAATCTTTTAATTGCGCCAACTCACTTGCGAGAAGTCAAACACAGTATCTTTATGTTTGAAGGCCTGTGATTATCTCTTTGCTACCGATTTTCCGCCTTTTTGTGCTTAGGAACGGAGGATGAAAGCCAGAGTTAAAAGAGAAAGCTGATGATCAGCGTTATGATACCGATAAAACCTGATTGCTCCTGTTTGGTTTTGTCGAATAGAAACTAACCCTGTAATCATCAGTTTATTCCGCCTCCTTCATGCTACAGGCCCCTGAAGTGACATGAATTATTGTTTTGACGATTTCTGAGAAGTAAAGTGAATCTGCATGGACTTCTTTCCACTCCTGCTTTCTGAGTCTGTTCGTCTTTTTCAGGGCCATACATAGTGTATATGCTAAGAGAAACTGACATACTAGAGGACTGGACAGCCATCAAGAAGG[T/C]ATTAATTATGAGTTATCAACCCTTCACTCACTGTAAAAATGTTTTATGGATCGTGATCTTTACCTTTTCTGTCTTTCAGGCAAAAGCAGCACTGATGCCCCTGAAGAAGAAAGCAGACAGTAAGTCAATTATTAAATGGGAATATTTATTTATGTTCATCATTCAAGCTTTCCTGTCGCTTTCTGTTTTTTATGCAGCTACATTGGGAGGTCAAGGTAGTCAGATGAACCTCATTAAACTTTGAAAAAACTGAGTGCTAAAATTAACTCATTGTATATTTATTAATGAAAATCACATGCGCTGACCATCTGGGACCTTGCCTTGTGCTTAATATATTTCACCAATGAATTCTTTCTCAAAAGAACAGAACAGGTTTACAGTGCAAATTGGTGTTTCTGTATAATAGTGAACTGTACAATGTTGTACAATCATAATTCAAGGTTCATGTTTGGTTTTAAGTAGAAAAGTGTTGCATGTTTTAAATAGCGCAATCTTTTACT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31610
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Essential Splice Site, Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000073673 None None 265 None 7
ENSDART00000073675 Essential Splice Site 270 271 None 10
ENSDART00000121545 Essential Splice Site 270 271 None 10
ENSDART00000126714 Missense 246 314 9 11
Genomic Location (Zv9):
Chromosome 7 (position 60887235)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 60106200
GRCz11 7 60411437
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTCTTTCAGGCAAAAGCAGCACTGATGCCCCTGAAGAAGAAAGCAGACAG[T/A]AAGTCAATTATTAAATGGGAATATTTATTTATGTTCATCATTCAAGCTTT
Long Flanking Sequence:
TTTATGTTTGAAGGCCTGTGATTATCTCTTTGCTACCGATTTTCCGCCTTTTTGTGCTTAGGAACGGAGGATGAAAGCCAGAGTTAAAAGAGAAAGCTGATGATCAGCGTTATGATACCGATAAAACCTGATTGCTCCTGTTTGGTTTTGTCGAATAGAAACTAACCCTGTAATCATCAGTTTATTCCGCCTCCTTCATGCTACAGGCCCCTGAAGTGACATGAATTATTGTTTTGACGATTTCTGAGAAGTAAAGTGAATCTGCATGGACTTCTTTCCACTCCTGCTTTCTGAGTCTGTTCGTCTTTTTCAGGGCCATACATAGTGTATATGCTAAGAGAAACTGACATACTAGAGGACTGGACAGCCATCAAGAAGGTATTAATTATGAGTTATCAACCCTTCACTCACTGTAAAAATGTTTTATGGATCGTGATCTTTACCTTTTCTGTCTTTCAGGCAAAAGCAGCACTGATGCCCCTGAAGAAGAAAGCAGACAG[T/A]AAGTCAATTATTAAATGGGAATATTTATTTATGTTCATCATTCAAGCTTTCCTGTCGCTTTCTGTTTTTTATGCAGCTACATTGGGAGGTCAAGGTAGTCAGATGAACCTCATTAAACTTTGAAAAAACTGAGTGCTAAAATTAACTCATTGTATATTTATTAATGAAAATCACATGCGCTGACCATCTGGGACCTTGCCTTGTGCTTAATATATTTCACCAATGAATTCTTTCTCAAAAGAACAGAACAGGTTTACAGTGCAAATTGGTGTTTCTGTATAATAGTGAACTGTACAATGTTGTACAATCATAATTCAAGGTTCATGTTTGGTTTTAAGTAGAAAAGTGTTGCATGTTTTAAATAGCGCAATCTTTTACTAGCATGATAAAACTGGTTGCACTTTGCTATATGCAACAGTATGGGTACTTAAGGAGTACTTGTATATAGGGCTGGGCAATAATAAGATAACAATAATTATGACAATATATATTTTTTCGAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa7095
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000073673 None None 265 None 7
ENSDART00000073675 None None 271 None 10
ENSDART00000121545 None None 271 None 10
ENSDART00000126714 Nonsense 262 314 10 11
Genomic Location (Zv9):
Chromosome 7 (position 60890988)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 60109953
GRCz11 7 60415190
KASP Assay ID:
554-5120.1 (used for ordering genotyping assays)
KASP Sequence:
GAAGATGAAGTTGCTTTTAAACAAGCAGATGTCTGTGCAATGTGAATTTT[G/A]GGGTCTTTTCTATAATGGAGAGAGACTCTCTAAAGACAGAACTGTTGATC
Long Flanking Sequence:
AATAAATTAGGCTTGTTTAACTACATATCTTTTATATGAAGATGGTTGTATGAATTTGTATTCATTGCATTTGTGTAGTTAAGTTAAGAGATGATGTAAGCTATGCAAAATAAATTTGCTCTGGTTGACACTGGATGTTTTTCTATTAAGTAAAACAAAAACTAAATATAATTACTAAATACAAATGTGTTCACAAAATAATAAAAACTAAATCATATATAACCAAACCATTAATGGAAACTAAAACTAAACTGAAACGTACAGCAAATTTGAAAAATGTATTGACATATTCAAAAATCCAAAACAGGTCTAGTCCAAAAACAGATCAAATGTCTCTTGGCACTCACAGCTAGTTCACACAAAGATTGTCCTGCACTCTTGATCGTATCATATTTAATCACTGTAGTATGTGTGCAGTGACAAAATGTCTTGAAAATAGAGATCATTAATGAAGATGAAGTTGCTTTTAAACAAGCAGATGTCTGTGCAATGTGAATTTT[G/A]GGGTCTTTTCTATAATGGAGAGAGACTCTCTAAAGACAGAACTGTTGATCTAGAGGTTAATAACAACATCCCAGCACAGTCACTAGAGAATAAGGCATAAGACTGCATCTGTGTTCACTTTGGCTTGTTTACAAAACTGAAATGGTCTTCTTTTTTTGTCTGTGTTTCTCTTAGGGTCGTAATAAAAGGGATCAGCACAGGAGAGGTCTGGTTCAAGCGCACAGATGGCACCAAAACCAAAATCTACATCTCTTAACTTCAGAAAGGCAAATGTGCCATACGAAAAGCTTAGAGACGATAAATTACACTCAGAGAGTGTGTGAGCCTACCCTTTAATAATTACCAAATAACACACACATTTACCAACACATTGTAAAACTGCATCTAATGCTATTCACTGGTATTGAACAGACCATAGGATGTTTATTATGTCTCCATTGACTTTTTGTCTCAGATCAATGTTGCCCTTTTTGATTAGGTTTTCCTGATGTTATTATAAA
Associated Phenotype:
Not determined