ZMP

gc2

Ensembl ID:

ENSDARG00000018329

ZFIN ID:

ZDB-GENE-011128-8

Description:

guanylyl cyclase 2 [Source:RefSeq peptide;Acc:NP_001103165]

Human Orthologue:

GUCY2F

Human Description:

guanylate cyclase 2F, retinal [Source:HGNC Symbol;Acc:4691]

Mouse Orthologue:

Gucy2f

Mouse Description:

guanylate cyclase 2f Gene [Source:MGI Symbol;Acc:MGI:105119]

Alleles

There are 4 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa34182	Nonsense	Mutation detected in F1 DNA	Not yet available
sa41018	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa34182

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000098648	Nonsense	330	1107	2	18
ENSDART00000098649	Nonsense	322	1099	3	19
ENSDART00000125807	None	None	259	None	7

Genomic Location (Zv9):

Chromosome 7 (position 52746023)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	7	51015773
GRCz11	7	51290843

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GATGCTGTGCTCACGATCACTATTGAGTCTCCAAAGGAACAGTCTTTTTA[T/A]CAAGCTTTTGAAAAGGCACAGGAGGATGGAGAGTTACCCAAACACCTCAA

Long Flanking Sequence:

TTTCAACATTTTACTTGTACGCTATTCTAAAACTTACAATGCCAAATTTCTTTTATCCTAGTAATTTAAGAGTTTTGCTGCTTATATAAACTACCTATTTAAAATGAGCTGAAACAACACATTTCTTGAGATTTTATTGGGACAACTTAATTGTGTTCAATGCATTTACTACAGTGCATGTATACTTTCTCAGCATCACACTCAAGCATTTAAAAGTCTGAACTGTCCTTTCCTCTTCTCAATGCTTTGTTTGCAGTGGTCATCTTGGTCATGCACTCTGTGTTAATTGGTGGAAGAACCCAGAAGCTGCTGCTGGAAACGGCACATGACATGCGGATGACAGACGGCTCGTTGGTGTTTATGTCCTACGATACTCTCTTTTACAGTCTGCCCTACCATCACGTTACTCAACCAGCCCTGCGCTATAACAGCAAGCTGCTACGTGCCTATGATGCTGTGCTCACGATCACTATTGAGTCTCCAAAGGAACAGTCTTTTTA[T/A]CAAGCTTTTGAAAAGGCACAGGAGGATGGAGAGTTACCCAAACACCTCAAACCACAGCAGGTACAAAGACTGTTTACATATGGCGTTACTTTTTTTGTACTAAGTTAATGGCTAATATCACCATCATGCATGTTCTGGTTTTGGAGAGTTATGCTTCTGGGTAAGTTTATTATAGTTTTAAAATGAATTTTAAAAGCAATAAACAGCAACACGGTGGCTCAGTGGTTAGCACTGTTGCCTCACAGCAAGAAGGTTGCTGGTTCAAGCCCGGCTGGGTCAGTTGGCATTTCTGTGTGCAGTTTGCATGTTCTCCCTGTGTTTGCGTGGGTTTCCTCCAGGTGCTCCGGTTTCCCCCACAGTCCAAAGAGATGCGCTATAGGTAAATTTAGTGAGCTAAATTGGCCGAAGTGTATATGTGTAAATGAGTGTGTATGGGTGTTTCCCCATAATGGGTTGCATCTGGAAGGGCATCCGCTGTGTACAACATATTGAATTATAAG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa41018

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000098648	Essential Splice Site	350	1107	2	18
ENSDART00000098649	Essential Splice Site	342	1099	3	19
ENSDART00000125807	None	None	259	None	7

Genomic Location (Zv9):

Chromosome 7 (position 52745961)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	7	51015711
GRCz11	7	51290781

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AAAGGCACAGGAGGATGGAGAGTTACCCAAACACCTCAAACCACAGCAGG[T/C]ACAAAGACTGTTTACATATGGCGTTACTTTTTTTGTACTAAGTTAATGGC

Long Flanking Sequence:

AATTTAAGAGTTTTGCTGCTTATATAAACTACCTATTTAAAATGAGCTGAAACAACACATTTCTTGAGATTTTATTGGGACAACTTAATTGTGTTCAATGCATTTACTACAGTGCATGTATACTTTCTCAGCATCACACTCAAGCATTTAAAAGTCTGAACTGTCCTTTCCTCTTCTCAATGCTTTGTTTGCAGTGGTCATCTTGGTCATGCACTCTGTGTTAATTGGTGGAAGAACCCAGAAGCTGCTGCTGGAAACGGCACATGACATGCGGATGACAGACGGCTCGTTGGTGTTTATGTCCTACGATACTCTCTTTTACAGTCTGCCCTACCATCACGTTACTCAACCAGCCCTGCGCTATAACAGCAAGCTGCTACGTGCCTATGATGCTGTGCTCACGATCACTATTGAGTCTCCAAAGGAACAGTCTTTTTATCAAGCTTTTGAAAAGGCACAGGAGGATGGAGAGTTACCCAAACACCTCAAACCACAGCAGG[T/C]ACAAAGACTGTTTACATATGGCGTTACTTTTTTTGTACTAAGTTAATGGCTAATATCACCATCATGCATGTTCTGGTTTTGGAGAGTTATGCTTCTGGGTAAGTTTATTATAGTTTTAAAATGAATTTTAAAAGCAATAAACAGCAACACGGTGGCTCAGTGGTTAGCACTGTTGCCTCACAGCAAGAAGGTTGCTGGTTCAAGCCCGGCTGGGTCAGTTGGCATTTCTGTGTGCAGTTTGCATGTTCTCCCTGTGTTTGCGTGGGTTTCCTCCAGGTGCTCCGGTTTCCCCCACAGTCCAAAGAGATGCGCTATAGGTAAATTTAGTGAGCTAAATTGGCCGAAGTGTATATGTGTAAATGAGTGTGTATGGGTGTTTCCCCATAATGGGTTGCATCTGGAAGGGCATCCGCTGTGTACAACATATTGAATTATAAGGTTCTATCTGACATTTTTGTCAAAATTAAGTTACTGACATATTCTTATTAAATGACAACTTA

Associated Phenotype:

Not determined