Busch Lab

ZMP

map2k5

Ensembl ID:
ENSDARG00000011851
ZFIN ID:
ZDB-GENE-030131-1517
Description:
dual specificity mitogen-activated protein kinase kinase 5 [Source:RefSeq peptide;Acc:NP_001107789]
Human Orthologue:
MAP2K5
Human Description:
mitogen-activated protein kinase kinase 5 [Source:HGNC Symbol;Acc:6845]
Mouse Orthologue:
Map2k5
Mouse Description:
mitogen-activated protein kinase kinase 5 Gene [Source:MGI Symbol;Acc:MGI:1346345]

Alleles

There are 8 alleles of this gene:

Allele Name Consequence Status Availability
sa20994 Essential Splice Site Available for shipment Available now
sa20993 Essential Splice Site Available for shipment Available now
sa20992 Essential Splice Site Available for shipment Available now
sa17068 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa20994
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000052404 Essential Splice Site 120 450 5 22
Genomic Location (Zv9):
Chromosome 7 (position 35394467)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 33779753
GRCz11 7 34050903
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTTTCAGCCGGTAAGACCCCAGGGATCCGCAACATTCACGGCCTGAAGG[T/C]ATGTGTCTCAATGATTGTTTCAGCAGAGTTGGGTATGGATCGGTTATGCT
Long Flanking Sequence:
TGTCACTTTAAGCTGTATAGAAGTGTCTTGATAAATATGTAGTAAAATATTATTTACTGTCATCATTGCAAAGATAAAATAAATCAGGTATTAGAAATACGTTTTTAAAACTATTATGCTTAGAAGTGTGCTGAAACAATCTTCCTTCCATTAAACAGAAATTGGGGAAAAAAAATAAACTGGGGCGCTAATAATTTAGGGGGGCTAATAATTCTGACTTCAACTGTGTGTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATACATACACACACACACACACACACATTTTTTTTTACACCTCATTATGTCTGTCTTGTTGTGTTGCAGGTAGATTCGTGCAATCATTTTAAACGTTTAAAATATTCTGCTCGTGTTCTTTTTCTTTGGCCTCATGTGATCTACAATCTAGTCAATTTTCTTTTCAGCCGGTAAGACCCCAGGGATCCGCAACATTCACGGCCTGAAGG[T/C]ATGTGTCTCAATGATTGTTTCAGCAGAGTTGGGTATGGATCGGTTATGCTGTGTACCACTTATTGAAATGTCAATTGAAGTCAAGACTGTCTCTTTTTCTGTCTGTCCCTCATTTTCTACTCTCCCATCACTCTTTGTTGTATTTTTTATTATCTTGCTTTTGATTTGATGGGAAGCTTTTATATAGAAGTTATTGAAAATAAAATGTTTTGTTAAAATACAAATATACACTATAAAAATGCAATTAATATTTTCCAGTCTCAAACATTGTGGATGCAGTTTTCTTGAGAAAGAAAATAAAAATCAGACAATCGAAATTCCCACAGCTGTTGGTTTTTCAGAGAAAAAAATCTTTGTTGCTTAAATGTCAAGGGTTTATGAGTTCCCAGCGTAAATATATTAATGTATTTGCTTATTATTATGAGATTGTTGTCATTTTTATTTGTTTGCTGACCTAATTAAAGCTTTTGTTGTTGATTTGTAATTATTTTAAATTATTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20993
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000052404 Essential Splice Site 378 450 19 22
Genomic Location (Zv9):
Chromosome 7 (position 35346731)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 33741071
GRCz11 7 34012221
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCCCCCTCTATCGCAGCCTCTTCAGTTATTGCAGTGCATTGTTGATGAGG[T/C]GAGTCTGTGTCCCATGTACGAAACCGTCCCTAATGGTGTGGAAAGCTGAT
Long Flanking Sequence:
GTGATCATCAGCATGTCCTGGTGCAGTGCTTGTGATTGTAACATGCTAATTGCATGTTTTCACTCTCGCTTTTTCATTCTCACCTAAATCCTTTTCTCCCTTTTTTCTCCTTATACAGATTCAAAAGAACCAGGGCTCTTTAATGGTAAGTGTTTTTCGTGCATTTCCAGAGATGTAGGCGGCTCTTCTTGCAACCCCTCACAGTTTTCATCTCACCTCGCATGGTTGCCTCCCTCTAAAGTTAATACCAGACAATAATACGCTCCATCTTAACAGCCTGTATTCAGATTAGGTTCCATTAGAAATAAGAAAACATTACAGATCAAATGGCTTTTTCCGAGTCAGAGTGCATTTGATTAAGCTGTATTGCTACCTGTTTTATTGCATTAATGATTTTATTTCCTTTGCACTGTAAGGACGTTGTATGGGGTCTAATCTCTTTTTCTTCTACCCCCCTCTATCGCAGCCTCTTCAGTTATTGCAGTGCATTGTTGATGAGG[T/C]GAGTCTGTGTCCCATGTACGAAACCGTCCCTAATGGTGTGGAAAGCTGATATTTTGTTTCCTAATGAAGCGAGGTGCATTATCAGCTCTGTTCAGGGTTTAAGCTCTGAAGAGCCAGAGCCGTCAAGAGCACGGTCGTGCTGAAATCAAGGCCTCGAACGAAACAATTGGCATAACTCTGGATTTGGCCGTTTTTAGCTAAACATGTGGGAAAAATGTAGCTGTTCCGAAGTAAATGGATAGTTCACCAAAACATGAAAATGCACTGAACATTAATTTAATCTCAAGTGGTTCAAACCTTTATGAGTTTCTTTTTCCTGATAAACACATAAGAAGATGTGTTGAAAAATGTAGGGCTGCAAGATATTGAAAAAACATGACATTGCAATGTTTTATTTTTTTTCAATATATATTGCAATATGAATACAATTTCACCAGATGGCTGGATATCTCGATTAGGAAAGAAATAGTTAATTTTTAACTTGTTTAACTTTATGGTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20992
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000052404 Essential Splice Site 399 450 20 22
ENSDART00000052404 Essential Splice Site 399 450 20 22
Genomic Location (Zv9):
Chromosome 7 (position 35331864)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 33726204
GRCz11 7 33997354
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCCAGTTGGTCAGTTCAGTGAGAAATTTGTCCACTTCATTACACAATGG[T/A]GAGTGTTTCTAATAACGAACACCTGTTTCTTCCTTTTGTGCCTGTCATAC
Long Flanking Sequence:
GCTTTAATTTAATTGTTTTCATTGAGTCTGTTCTTTAGCCTGATGCAATTTGTTCACCATATCAAGATGATATTGAGGTTGCGGTAACTAAATGTTCTTATTAACTGTATGCTTTCTGCATATCTAATGTTTATCTTTCTCACTGCAAGTGTGAGCTTTTTGTCTGTCTGCATGTTTGTCCCATCTCCTGTGCGTCAGAAATCTTCACCTGTCCAACAATAGAGAGGTTCAGGTGTTTCCAAAATGTAATATACGCAGCTGCTTTTGAATGTCCACACATAGAACATACCTCATTATGGATCGTAACCCTTCTGCAACCTAGTCAAGGCCAGCCGAACCCACAAGTTAAATTCATTTTTGGAAACACATATCCTGATATGCTCATTCTGTCTTGTGGGTATGTTTGTGATCATGTGTATGCATGTCTGTTTTTTTAGGATCCCCCTGTACTTCCAGTTGGTCAGTTCAGTGAGAAATTTGTCCACTTCATTACACAATGG[T/A]GAGTGTTTCTAATAACGAACACCTGTTTCTTCCTTTTGTGCCTGTCATACATAAATAACCCTCATGTCGTGATGAATTTGCATTGGTAAGCAAAAACTAATGATAAGTAGAAGCTAATCATGGTACATGTTGTGAATATTATGAAATCAAAGAAAAATTATTACTGACGTTCACTGATAATACCAAGTCTATTCTGTCCACCCAGGCTCAGTTTTTGGCAGTCAAAAATAAAAACGAATTCTGTGAAATATTATTTTCATTTAAAATGCCTATTTTCTGTGTAGATTTATCATTTAATGTACTAATGATCAATATTTATTTATATGTGTGTGGGGGTTTATTTACAACTTATATTTAGAGTTAATACTGTAATAGAAAAATATATGCCTTAAATCAGGCTTTACAACCTGCTTTCCCTTGTGAAGCCAATACGGAAGTGACTGTAACTGCAATTCATCGACTCGTCTTTGGAGGCTGGCTTCATAAACTCCAGATGTTCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17068
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000052404 Essential Splice Site 399 450 20 22
ENSDART00000052404 Essential Splice Site 399 450 20 22
Genomic Location (Zv9):
Chromosome 7 (position 35331864)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 33726204
GRCz11 7 33997354
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTCCAGTTGGTCAGTTCAGTGAGAAATTTGTCCACTTCWTTACACAATGG[T/G]GAGTGTTTCTAATAACGAACACCTGTTTCTTCCTTTTGTGYCTGTCATAC
Long Flanking Sequence:
GCTTTAATTTAATTGTTTTCATTGAGTCTGTTCTTTAGCCTGATGCAATTTGTTCACCATATCAAGATGATATTGAGGTTGCGGTAACTAAATGTTCTTATTAACTGTATGCTTTCTGCATATCTAATGTTTATCTTTCTCACTGCAAGTGTGAGCTTTTTGTCTGTCTGCATGTTTGTCCCATCTCCTGTGCGTCAGAAATCTTCACCTGTCCAACAATAGAGAGGTTCAGGTGTTTCCAAAATGTAATATACGCAGCTGCTTTTGAATGTCCACACATAGAACATACCTCATTATGGATCGTAACCCTTCTGCAACCTAGTCAAGGCCAGCCGAACCCACAAGTTAAATTCATTTTTGGAAACACATATCCTGATATGCTCATTCTGTCTTGTGGGTATGTTTGTGATCATGTGTATGCATGTCTGTTTTTTTAGGATCCCCCTGTACTTCCAGTTGGTCAGTTCAGTGAGAAATTTGTCCACTTCATTACACAATGG[T/G]GAGTGTTTCTAATAACGAACACCTGTTTCTTCCTTTTGTGCCTGTCATACATAAATAACCCTCATGTCGTGATGAATTTGCATTGGTAAGCAAAAACTAATGATAAGTAGAAGCTAATCATGGTACATGTTGTGAATATTATGAAATCAAAGAAAAATTATTACTGACGTTCACTGATAATACCAAGTCTATTCTGTCCACCCAGGCTCAGTTTTTGGCAGTCAAAAATAAAAACGAATTCTGTGAAATATTATTTTCATTTAAAATGCCTATTTTCTGTGTAGATTTATCATTTAATGTACTAATGATCAATATTTATTTATATGTGTGTGGGGGTTTATTTACAACTTATATTTAGAGTTAATACTGTAATAGAAAAATATATGCCTTAAATCAGGCTTTACAACCTGCTTTCCCTTGTGAAGCCAATACGGAAGTGACTGTAACTGCAATTCATCGACTCGTCTTTGGAGGCTGGCTTCATAAACTCCAGATGTTCA
Associated Phenotype:
Not determined