ZMP
map2k5
Ensembl ID:
ZFIN ID:
Description:
dual specificity mitogen-activated protein kinase kinase 5 [Source:RefSeq peptide;Acc:NP_001107789]
Human Orthologue:
MAP2K5
Human Description:
mitogen-activated protein kinase kinase 5 [Source:HGNC Symbol;Acc:6845]
Mouse Orthologue:
Map2k5
Mouse Description:
mitogen-activated protein kinase kinase 5 Gene [Source:MGI Symbol;Acc:MGI:1346345]
Alleles
There are 8 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa20994 | Essential Splice Site | Available for shipment | Available now |
| sa34111 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa34110 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa20993 | Essential Splice Site | Available for shipment | Available now |
| sa17068 | Essential Splice Site | Available for shipment | Available now |
| sa20992 | Essential Splice Site | Available for shipment | Available now |
Mutation Details
Allele Name:
sa20994
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000052404 | Essential Splice Site | 120 | 450 | 5 | 22 |
Genomic Location (Zv9):
Chromosome 7 (position 35394467)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 33779753 |
| GRCz11 | 7 | 34050903 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTTTCAGCCGGTAAGACCCCAGGGATCCGCAACATTCACGGCCTGAAGG[T/C]ATGTGTCTCAATGATTGTTTCAGCAGAGTTGGGTATGGATCGGTTATGCT
Long Flanking Sequence:
TGTCACTTTAAGCTGTATAGAAGTGTCTTGATAAATATGTAGTAAAATATTATTTACTGTCATCATTGCAAAGATAAAATAAATCAGGTATTAGAAATACGTTTTTAAAACTATTATGCTTAGAAGTGTGCTGAAACAATCTTCCTTCCATTAAACAGAAATTGGGGAAAAAAAATAAACTGGGGCGCTAATAATTTAGGGGGGCTAATAATTCTGACTTCAACTGTGTGTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATACATACACACACACACACACACACATTTTTTTTTACACCTCATTATGTCTGTCTTGTTGTGTTGCAGGTAGATTCGTGCAATCATTTTAAACGTTTAAAATATTCTGCTCGTGTTCTTTTTCTTTGGCCTCATGTGATCTACAATCTAGTCAATTTTCTTTTCAGCCGGTAAGACCCCAGGGATCCGCAACATTCACGGCCTGAAGG[T/C]ATGTGTCTCAATGATTGTTTCAGCAGAGTTGGGTATGGATCGGTTATGCTGTGTACCACTTATTGAAATGTCAATTGAAGTCAAGACTGTCTCTTTTTCTGTCTGTCCCTCATTTTCTACTCTCCCATCACTCTTTGTTGTATTTTTTATTATCTTGCTTTTGATTTGATGGGAAGCTTTTATATAGAAGTTATTGAAAATAAAATGTTTTGTTAAAATACAAATATACACTATAAAAATGCAATTAATATTTTCCAGTCTCAAACATTGTGGATGCAGTTTTCTTGAGAAAGAAAATAAAAATCAGACAATCGAAATTCCCACAGCTGTTGGTTTTTCAGAGAAAAAAATCTTTGTTGCTTAAATGTCAAGGGTTTATGAGTTCCCAGCGTAAATATATTAATGTATTTGCTTATTATTATGAGATTGTTGTCATTTTTATTTGTTTGCTGACCTAATTAAAGCTTTTGTTGTTGATTTGTAATTATTTTAAATTATTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa34111
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000052404 | Nonsense | 126 | 450 | 6 | 22 |
Genomic Location (Zv9):
Chromosome 7 (position 35390401)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 33775742 |
| GRCz11 | 7 | 34046892 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TAGCACAGGTTGTGATTGTCTTTGTTTGCCCGCAGGTGAACACGCGGCCC[G/T]AATCCTCGAGTGGCAGGAGCTCCTCTGCAGCTGATTCCCGCTCCAGCGAT
Long Flanking Sequence:
GTTTGATTTTCAGCTCTATTGGCTTGAAAAGGGTATAAAAAACCCAGATAAACTGACTTAAATGAGGTCTTCATAGACACTAATTAAGAAGAGAATCACTGCTTTACTGCTTCACACTATTTGACCTTCAGACCTCAATTAATCTGCTTATTTATACAGGGACTCTCTTTGAGCCCATTTCCTTCATTCTCCCACAGCGATCCATTAGTGCGGCTCTGACAATAAGCAGCTTCATGAATCCTCTTTAATGACAAATAAAGGACGTGATGTTGATTCATCCATTTTTTTTTCTTCACCCAAGGATGTTCCCAGAGTTATATTTAATTTTGCCTGATAGATGAAGTGACCCCTTTCCTCAAGCCTCTATCTCTAGATCTCACTGTCTCCCCCACAAAAGCCAATTAACCTTGCGGCCAAACCAGGCAGTTTGCTGTTGAATCACAGGTTAATTAGCACAGGTTGTGATTGTCTTTGTTTGCCCGCAGGTGAACACGCGGCCC[G/T]AATCCTCGAGTGGCAGGAGCTCCTCTGCAGCTGATTCCCGCTCCAGCGATAGGTGAGTGATCCCACATCACATCTGCACTCATTAAGTGGAGGAAACACAGGGAAAAGGCTTCATACCAGTGTTTGTTTTGTTTATTAATACTGAAAGGTGAAGCTTGCATTTCAAGTGCATACATTGATGACTTTGCTGGAATGAGTGTTTTGAAATGTAGTTAATGATAGAAATTAACAGGATACGGAGTGGATAAACCAACATACACTACTGGTCAAATGTTTGATTATTTTATTTATTTTTTTTTTTTTAATTTTTAGAAAATTATTCTGTTCATCAAGGTGACATTTATTAAATGTAAAATGTTAAATTGTTAAATATTTATTAATATTTTAAATAACTGCTTATTGTATGTGGTTTAAAATAAAATTATTACTCTTGTCATTATTGCTTTTATTACTATTATCATTAATAATAATAATAATAATAATAATAGTAATAATAATAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa34110
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000052404 | Essential Splice Site | 246 | 450 | 11 | 22 |
| ENSDART00000052404 | Essential Splice Site | 246 | 450 | 11 | 22 |
Genomic Location (Zv9):
Chromosome 7 (position 35361942)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 33756282 |
| GRCz11 | 7 | 34027432 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCTTTCTTTGTGGAGAACAGAATATCGATATGCACTGAGTTTATGGATGG[T/A]AAGTCTCATTTGCTTAGACATTGTCAGGCATCTGGGATTCAACATTTTCA
Long Flanking Sequence:
TAAATAACCACCATTCAAATTCTTGAAAATATTTGCAATGTCATTTCACAATAATATAAATTTTCTATTAGTATTAAAACCATCAGGTGAATCATACAAAAGTTCCATTAACTAGCATGTACTCTAACACACAAGTGTCAAACTCAGTTCCTGGAGGGTCGCAAATCTGCACAGTTTAGTTTTAACCCTAATTAAACACCTGATCAAACTAATTGTAATTAAGTCCTTTAGGCTTGTTTGATACCTACTGATTTGTGTGATGACACAGAGTTGGAACTAAACTGTGCTGTGCTGCGGCCCTCCAGGAACTGAGTTTGACACCCCTGCTCTAACAGTAGCACAAATAAATGGATTATTGCATTGTAAGTCCTACCAGTCCCAAGCATTTAAAAAATAAAATTGTGATTGTGTTTACAGTGTGATTCTCCGTACATCATAAAGTTCTACAGTGCTTTCTTTGTGGAGAACAGAATATCGATATGCACTGAGTTTATGGATGG[T/A]AAGTCTCATTTGCTTAGACATTGTCAGGCATCTGGGATTCAACATTTTCAGTAAAACATCAATCCGATTATACACAAATTTAAAACAGTCATTTGATTTTGATGTAGGTGGCTCTCTGGATGTTTATTGGAGAATCCCAGAGCATGTTTTGGGCAGGATTGCTGTTGCGGTAAGTCCTTTCAATCCATAGAGCTGTTGTTGAGTAAGCATATCTTAAAAGATTGGATTTTTTTTATATTTCAGTGAATTGAGGCGAGTTTGTTTGATGTCTCAATTGTCCTCACTTCTTTAGTGAGATATTAAAAGGACCCACTAGTGAGGACAGTTTTACTGGTTGCTAAAAAAAAATGCTTATAAATTAGCCAGAACATGCTTTTATTATTATTATTATTATTATTATTATCATCTAAAATTTCGTACATGTTTCTGTAAAGGGTTGGGAAGAGATAGAGGTAGGCCATAGACAGTGTCATTAACCTGATAGAGAAACAATATCTATT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa20993
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000052404 | Essential Splice Site | 378 | 450 | 19 | 22 |
Genomic Location (Zv9):
Chromosome 7 (position 35346731)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 33741071 |
| GRCz11 | 7 | 34012221 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCCCCCTCTATCGCAGCCTCTTCAGTTATTGCAGTGCATTGTTGATGAGG[T/C]GAGTCTGTGTCCCATGTACGAAACCGTCCCTAATGGTGTGGAAAGCTGAT
Long Flanking Sequence:
GTGATCATCAGCATGTCCTGGTGCAGTGCTTGTGATTGTAACATGCTAATTGCATGTTTTCACTCTCGCTTTTTCATTCTCACCTAAATCCTTTTCTCCCTTTTTTCTCCTTATACAGATTCAAAAGAACCAGGGCTCTTTAATGGTAAGTGTTTTTCGTGCATTTCCAGAGATGTAGGCGGCTCTTCTTGCAACCCCTCACAGTTTTCATCTCACCTCGCATGGTTGCCTCCCTCTAAAGTTAATACCAGACAATAATACGCTCCATCTTAACAGCCTGTATTCAGATTAGGTTCCATTAGAAATAAGAAAACATTACAGATCAAATGGCTTTTTCCGAGTCAGAGTGCATTTGATTAAGCTGTATTGCTACCTGTTTTATTGCATTAATGATTTTATTTCCTTTGCACTGTAAGGACGTTGTATGGGGTCTAATCTCTTTTTCTTCTACCCCCCTCTATCGCAGCCTCTTCAGTTATTGCAGTGCATTGTTGATGAGG[T/C]GAGTCTGTGTCCCATGTACGAAACCGTCCCTAATGGTGTGGAAAGCTGATATTTTGTTTCCTAATGAAGCGAGGTGCATTATCAGCTCTGTTCAGGGTTTAAGCTCTGAAGAGCCAGAGCCGTCAAGAGCACGGTCGTGCTGAAATCAAGGCCTCGAACGAAACAATTGGCATAACTCTGGATTTGGCCGTTTTTAGCTAAACATGTGGGAAAAATGTAGCTGTTCCGAAGTAAATGGATAGTTCACCAAAACATGAAAATGCACTGAACATTAATTTAATCTCAAGTGGTTCAAACCTTTATGAGTTTCTTTTTCCTGATAAACACATAAGAAGATGTGTTGAAAAATGTAGGGCTGCAAGATATTGAAAAAACATGACATTGCAATGTTTTATTTTTTTTCAATATATATTGCAATATGAATACAATTTCACCAGATGGCTGGATATCTCGATTAGGAAAGAAATAGTTAATTTTTAACTTGTTTAACTTTATGGTTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa17068
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000052404 | Essential Splice Site | 399 | 450 | 20 | 22 |
| ENSDART00000052404 | Essential Splice Site | 399 | 450 | 20 | 22 |
Genomic Location (Zv9):
Chromosome 7 (position 35331864)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 33726204 |
| GRCz11 | 7 | 33997354 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTCCAGTTGGTCAGTTCAGTGAGAAATTTGTCCACTTCWTTACACAATGG[T/G]GAGTGTTTCTAATAACGAACACCTGTTTCTTCCTTTTGTGYCTGTCATAC
Long Flanking Sequence:
GCTTTAATTTAATTGTTTTCATTGAGTCTGTTCTTTAGCCTGATGCAATTTGTTCACCATATCAAGATGATATTGAGGTTGCGGTAACTAAATGTTCTTATTAACTGTATGCTTTCTGCATATCTAATGTTTATCTTTCTCACTGCAAGTGTGAGCTTTTTGTCTGTCTGCATGTTTGTCCCATCTCCTGTGCGTCAGAAATCTTCACCTGTCCAACAATAGAGAGGTTCAGGTGTTTCCAAAATGTAATATACGCAGCTGCTTTTGAATGTCCACACATAGAACATACCTCATTATGGATCGTAACCCTTCTGCAACCTAGTCAAGGCCAGCCGAACCCACAAGTTAAATTCATTTTTGGAAACACATATCCTGATATGCTCATTCTGTCTTGTGGGTATGTTTGTGATCATGTGTATGCATGTCTGTTTTTTTAGGATCCCCCTGTACTTCCAGTTGGTCAGTTCAGTGAGAAATTTGTCCACTTCATTACACAATGG[T/G]GAGTGTTTCTAATAACGAACACCTGTTTCTTCCTTTTGTGCCTGTCATACATAAATAACCCTCATGTCGTGATGAATTTGCATTGGTAAGCAAAAACTAATGATAAGTAGAAGCTAATCATGGTACATGTTGTGAATATTATGAAATCAAAGAAAAATTATTACTGACGTTCACTGATAATACCAAGTCTATTCTGTCCACCCAGGCTCAGTTTTTGGCAGTCAAAAATAAAAACGAATTCTGTGAAATATTATTTTCATTTAAAATGCCTATTTTCTGTGTAGATTTATCATTTAATGTACTAATGATCAATATTTATTTATATGTGTGTGGGGGTTTATTTACAACTTATATTTAGAGTTAATACTGTAATAGAAAAATATATGCCTTAAATCAGGCTTTACAACCTGCTTTCCCTTGTGAAGCCAATACGGAAGTGACTGTAACTGCAATTCATCGACTCGTCTTTGGAGGCTGGCTTCATAAACTCCAGATGTTCA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa20992
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000052404 | Essential Splice Site | 399 | 450 | 20 | 22 |
| ENSDART00000052404 | Essential Splice Site | 399 | 450 | 20 | 22 |
Genomic Location (Zv9):
Chromosome 7 (position 35331864)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 33726204 |
| GRCz11 | 7 | 33997354 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCCAGTTGGTCAGTTCAGTGAGAAATTTGTCCACTTCATTACACAATGG[T/A]GAGTGTTTCTAATAACGAACACCTGTTTCTTCCTTTTGTGCCTGTCATAC
Long Flanking Sequence:
GCTTTAATTTAATTGTTTTCATTGAGTCTGTTCTTTAGCCTGATGCAATTTGTTCACCATATCAAGATGATATTGAGGTTGCGGTAACTAAATGTTCTTATTAACTGTATGCTTTCTGCATATCTAATGTTTATCTTTCTCACTGCAAGTGTGAGCTTTTTGTCTGTCTGCATGTTTGTCCCATCTCCTGTGCGTCAGAAATCTTCACCTGTCCAACAATAGAGAGGTTCAGGTGTTTCCAAAATGTAATATACGCAGCTGCTTTTGAATGTCCACACATAGAACATACCTCATTATGGATCGTAACCCTTCTGCAACCTAGTCAAGGCCAGCCGAACCCACAAGTTAAATTCATTTTTGGAAACACATATCCTGATATGCTCATTCTGTCTTGTGGGTATGTTTGTGATCATGTGTATGCATGTCTGTTTTTTTAGGATCCCCCTGTACTTCCAGTTGGTCAGTTCAGTGAGAAATTTGTCCACTTCATTACACAATGG[T/A]GAGTGTTTCTAATAACGAACACCTGTTTCTTCCTTTTGTGCCTGTCATACATAAATAACCCTCATGTCGTGATGAATTTGCATTGGTAAGCAAAAACTAATGATAAGTAGAAGCTAATCATGGTACATGTTGTGAATATTATGAAATCAAAGAAAAATTATTACTGACGTTCACTGATAATACCAAGTCTATTCTGTCCACCCAGGCTCAGTTTTTGGCAGTCAAAAATAAAAACGAATTCTGTGAAATATTATTTTCATTTAAAATGCCTATTTTCTGTGTAGATTTATCATTTAATGTACTAATGATCAATATTTATTTATATGTGTGTGGGGGTTTATTTACAACTTATATTTAGAGTTAATACTGTAATAGAAAAATATATGCCTTAAATCAGGCTTTACAACCTGCTTTCCCTTGTGAAGCCAATACGGAAGTGACTGTAACTGCAATTCATCGACTCGTCTTTGGAGGCTGGCTTCATAAACTCCAGATGTTCA
Associated Phenotype:
Not determined