Busch Lab

ZMP

pik3r3

Ensembl ID:
ENSDARG00000034409
ZFIN ID:
ZDB-GENE-040426-743
Description:
phosphatidylinositol 3-kinase regulatory subunit gamma [Source:RefSeq peptide;Acc:NP_957437]
Human Orthologue:
PIK3R3
Human Description:
phosphoinositide-3-kinase, regulatory subunit 3 (gamma) [Source:HGNC Symbol;Acc:8981]
Mouse Orthologue:
Pik3r3
Mouse Description:
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55) Gene [Source:MGI Symbol;Acc:M

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa11674 Nonsense Available for shipment Available now
sa15730 Nonsense Available for shipment Available now
sa40723 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa33889 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa11674
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000040334 Nonsense 263 464 7 10

The following transcripts of ENSDARG00000034409 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 33248020)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 33565685
GRCz11 6 33550375
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGTATCTAAGGGTTTTTCAATTGATCTTTCTCAGGATTATGATGAACTAC[G/T]AGAAGCTTAAATCCCGTCTGGGTGAAATTCACGACAGTAAGACCCGGCTT
Long Flanking Sequence:
GCTCCAGGAGTATCACAATCAATATCAGGAGAAGAGTAAAGAATATGACAGACTCTACGAGGAGCACACAAAAACCTCACAGGTAAGCCTCTTAGAACATCGCTATTTGATCGATAGACATCCAACCTCTTAACTCCAGCCCCAAACGCAATGTGTATACAAACAATTCATTTGATTGCGAGAAGCCCATTAACCAAGTCTGTGAAGAGGCGCGTTCCTTTGAGGTTGCATCACATCCATTGATTTATCTTTCCTTTGATTGCAGGAGATCCAGATGAAACGTACCGCAATAGAGGCCTTCAATGAGACTATTAAAATTTTTGAAGAACAGTGTCACACACAGGAGCGCTACAGTAAGGAATACATTGAGCGATTCCGCAGAGAGGGCAACGACAAAGAGATTGAGAGGTACGCAGAGGTCACAATTAAGAGAGCTCTGGATTGTCAGCCTGTATCTAAGGGTTTTTCAATTGATCTTTCTCAGGATTATGATGAACTAC[G/T]AGAAGCTTAAATCCCGTCTGGGTGAAATTCACGACAGTAAGACCCGGCTTGAACAGGACCTGAAAACGCAGGCTCTGGACAACAGGGAGACGGACAAGAAAATGAACAGCTTAAAGCCAGATCTCATTCAGCTCCGAAAGATTAGAGATCAGTACCTTGTGTAAGCAAAACCATCCTTCACACACCATTCCAAGTCATCATTACTGTTATGTTTGAGTTGACTATTTTTCTGTCAAGTATAAACACTCTACTGACTAATGCTTTTTATTTATTACGCAGTTGGCTAAATCATAAAGGTGTACGACAGAAACGAATCAACGATTGGCTGGGCTTAAAAAATGAGACCACAGATGAGTAAGTAAAGTTTACTTAACTTTTGAGATCATGGATTTGCAAGTGGCTCCTGTAAAGCATCTAACACATTTTCTAACTACCACAGTGCCTACTTTGTCAGTGAGGAGGATGAGAATCTGCCACACTATGACGAGAAGAGCTGGTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15730
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000040334 Nonsense 314 464 7 10

The following transcripts of ENSDARG00000034409 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 33248175)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 33565840
GRCz11 6 33550530
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AACAGCTTAAAGCCAGATCTMATTCAGCTCCGAAAGATTAGAGAWCAGTA[C/A]CTTGTGTAAGCAAAASCATCCTTCACACACCATTCCAWGTCAKCATTACT
Long Flanking Sequence:
TATACAAACAATTCATTTGATTGCGAGAAGCCCATTAACCAAGTCTGTGAAGAGGCGCGTTCCTTTGAGGTTGCATCACATCCATTGATTTATCTTTCCTTTGATTGCAGGAGATCCAGATGAAACGTACCGCAATAGAGGCCTTCAATGAGACTATTAAAATTTTTGAAGAACAGTGTCACACACAGGAGCGCTACAGTAAGGAATACATTGAGCGATTCCGCAGAGAGGGCAACGACAAAGAGATTGAGAGGTACGCAGAGGTCACAATTAAGAGAGCTCTGGATTGTCAGCCTGTATCTAAGGGTTTTTCAATTGATCTTTCTCAGGATTATGATGAACTACGAGAAGCTTAAATCCCGTCTGGGTGAAATTCACGACAGTAAGACCCGGCTTGAACAGGACCTGAAAACGCAGGCTCTGGACAACAGGGAGACGGACAAGAAAATGAACAGCTTAAAGCCAGATCTCATTCAGCTCCGAAAGATTAGAGATCAGTA[C/A]CTTGTGTAAGCAAAACCATCCTTCACACACCATTCCAAGTCATCATTACTGTTATGTTTGAGTTGACTATTTTTCTGTCAAGTATAAACACTCTACTGACTAATGCTTTTTATTTATTACGCAGTTGGCTAAATCATAAAGGTGTACGACAGAAACGAATCAACGATTGGCTGGGCTTAAAAAATGAGACCACAGATGAGTAAGTAAAGTTTACTTAACTTTTGAGATCATGGATTTGCAAGTGGCTCCTGTAAAGCATCTAACACATTTTCTAACTACCACAGTGCCTACTTTGTCAGTGAGGAGGATGAGAATCTGCCACACTATGACGAGAAGAGCTGGTTTGTGGGGGACCTGAACCGAACGCAGTCAGAAGATTTGCTACATGGCAAACCTGACGGAGCTTTCCTCATCCGGGAAAGCAGCAAGAAAGGCTGTTACGCCTGCTCTGTTGTGTAAGTATCTTAAGATGTAGAACACGGTTCAGTGAGTGTGATGCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40723
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000040334 Essential Splice Site 316 464 7 10
ENSDART00000040334 Essential Splice Site 316 464 7 10

The following transcripts of ENSDARG00000034409 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 33248182)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 33565847
GRCz11 6 33550537
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TAAAGCCAGATCTCATTCAGCTCCGAAAGATTAGAGATCAGTACCTTGTG[T/G]AAGCAAAACCATCCTTCACACACCATTCCAAGTCATCATTACTGTTATGT
Long Flanking Sequence:
ACAATTCATTTGATTGCGAGAAGCCCATTAACCAAGTCTGTGAAGAGGCGCGTTCCTTTGAGGTTGCATCACATCCATTGATTTATCTTTCCTTTGATTGCAGGAGATCCAGATGAAACGTACCGCAATAGAGGCCTTCAATGAGACTATTAAAATTTTTGAAGAACAGTGTCACACACAGGAGCGCTACAGTAAGGAATACATTGAGCGATTCCGCAGAGAGGGCAACGACAAAGAGATTGAGAGGTACGCAGAGGTCACAATTAAGAGAGCTCTGGATTGTCAGCCTGTATCTAAGGGTTTTTCAATTGATCTTTCTCAGGATTATGATGAACTACGAGAAGCTTAAATCCCGTCTGGGTGAAATTCACGACAGTAAGACCCGGCTTGAACAGGACCTGAAAACGCAGGCTCTGGACAACAGGGAGACGGACAAGAAAATGAACAGCTTAAAGCCAGATCTCATTCAGCTCCGAAAGATTAGAGATCAGTACCTTGTG[T/G]AAGCAAAACCATCCTTCACACACCATTCCAAGTCATCATTACTGTTATGTTTGAGTTGACTATTTTTCTGTCAAGTATAAACACTCTACTGACTAATGCTTTTTATTTATTACGCAGTTGGCTAAATCATAAAGGTGTACGACAGAAACGAATCAACGATTGGCTGGGCTTAAAAAATGAGACCACAGATGAGTAAGTAAAGTTTACTTAACTTTTGAGATCATGGATTTGCAAGTGGCTCCTGTAAAGCATCTAACACATTTTCTAACTACCACAGTGCCTACTTTGTCAGTGAGGAGGATGAGAATCTGCCACACTATGACGAGAAGAGCTGGTTTGTGGGGGACCTGAACCGAACGCAGTCAGAAGATTTGCTACATGGCAAACCTGACGGAGCTTTCCTCATCCGGGAAAGCAGCAAGAAAGGCTGTTACGCCTGCTCTGTTGTGTAAGTATCTTAAGATGTAGAACACGGTTCAGTGAGTGTGATGCCACTAGTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33889
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000040334 Essential Splice Site 316 464 7 10
ENSDART00000040334 Essential Splice Site 316 464 7 10

The following transcripts of ENSDARG00000034409 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 33248182)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 33565847
GRCz11 6 33550537
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TAAAGCCAGATCTCATTCAGCTCCGAAAGATTAGAGATCAGTACCTTGTG[T/G]AAGCAAAACCATCCTTCACACACCATTCCAAGTCATCATTACTGTTATGT
Long Flanking Sequence:
ACAATTCATTTGATTGCGAGAAGCCCATTAACCAAGTCTGTGAAGAGGCGCGTTCCTTTGAGGTTGCATCACATCCATTGATTTATCTTTCCTTTGATTGCAGGAGATCCAGATGAAACGTACCGCAATAGAGGCCTTCAATGAGACTATTAAAATTTTTGAAGAACAGTGTCACACACAGGAGCGCTACAGTAAGGAATACATTGAGCGATTCCGCAGAGAGGGCAACGACAAAGAGATTGAGAGGTACGCAGAGGTCACAATTAAGAGAGCTCTGGATTGTCAGCCTGTATCTAAGGGTTTTTCAATTGATCTTTCTCAGGATTATGATGAACTACGAGAAGCTTAAATCCCGTCTGGGTGAAATTCACGACAGTAAGACCCGGCTTGAACAGGACCTGAAAACGCAGGCTCTGGACAACAGGGAGACGGACAAGAAAATGAACAGCTTAAAGCCAGATCTCATTCAGCTCCGAAAGATTAGAGATCAGTACCTTGTG[T/C]AAGCAAAACCATCCTTCACACACCATTCCAAGTCATCATTACTGTTATGTTTGAGTTGACTATTTTTCTGTCAAGTATAAACACTCTACTGACTAATGCTTTTTATTTATTACGCAGTTGGCTAAATCATAAAGGTGTACGACAGAAACGAATCAACGATTGGCTGGGCTTAAAAAATGAGACCACAGATGAGTAAGTAAAGTTTACTTAACTTTTGAGATCATGGATTTGCAAGTGGCTCCTGTAAAGCATCTAACACATTTTCTAACTACCACAGTGCCTACTTTGTCAGTGAGGAGGATGAGAATCTGCCACACTATGACGAGAAGAGCTGGTTTGTGGGGGACCTGAACCGAACGCAGTCAGAAGATTTGCTACATGGCAAACCTGACGGAGCTTTCCTCATCCGGGAAAGCAGCAAGAAAGGCTGTTACGCCTGCTCTGTTGTGTAAGTATCTTAAGATGTAGAACACGGTTCAGTGAGTGTGATGCCACTAGTC
Associated Phenotype:
Not determined