Busch Lab

ZMP

ABCC6 (2 of 3)

Ensembl ID:
ENSDARG00000016750
Description:
ATP-binding cassette, sub-family C (CFTR/MRP), member 6 [Source:HGNC Symbol;Acc:57]
Human Orthologue:
ABCC6
Human Description:
ATP-binding cassette, sub-family C (CFTR/MRP), member 6 [Source:HGNC Symbol;Acc:57]
Mouse Orthologue:
Abcc6
Mouse Description:
ATP-binding cassette, sub-family C (CFTR/MRP), member 6 Gene [Source:MGI Symbol;Acc:MGI:1351634]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa33821 Nonsense Available for shipment Available now
sa963 Essential Splice Site Available for shipment Available now
sa2285 Nonsense F2 line generated Not yet available
sa40643 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa31502 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa33821
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000065433 Nonsense 447 1507 10 31
Genomic Location (Zv9):
Chromosome 6 (position 10959520)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 10813146
GRCz11 6 11048573
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCAGTGTGGCTGGCACCCATTGAGGTCACACTCTGTCTCTTTTTTCTTTG[G/A]CAGGTGAGGGCTCATTTATTTGCTATTATAATATCTCAGTATTCGGGAAC
Long Flanking Sequence:
CCAGGTATACATCCATGCTAAAATATCAAGGTGAAAGACATCAAAGCTTGCGTAGTATAGACCCAGCTCCCGATATTGAGAATAGATTAACGGTTATTTTTTTTTCGCCAGATAAGAGTCTCGCGTTAACGCAGCAAGTTAACGCCGATAACAGCCCACCACTAAAATAAACATTCATTTCCATGATTTTATGGACCAAACAGGCTCAATGTAAAGATTAAGAAGGTGTCTGTTTTTGCGCATAATGTTGTTAGACTAACGAAACTATAATGTTGTGTTTAAACTTTCAAGCAACACAATTTTAATCAGTGCCTTTGTCTCTGCATTCTTGTTTTTTCTCAGTCTCTTGTTATGAACAGTTCAGCGCGCAGAACCTGCACAGTAGGGGAGATAGTCAATCTGGTGTCTGCCGATACACAGAAGCTGATGGATTTTGTGGTGTATTTCAATGCAGTGTGGCTGGCACCCATTGAGGTCACACTCTGTCTCTTTTTTCTTTG[G/A]CAGGTGAGGGCTCATTTATTTGCTATTATAATATCTCAGTATTCGGGAACGTGGCTGAATATTTGTTTTAGCTTTCCAATAAAAATAAGCAAGACTTTTCTTATTTGACTTATTTCAGCATTTGGGACCCTCAGCACTTGCGGGCATTGCCACAGTGATTTTCATCTTTCCTCTGAACGGATTTATTGCAAGAAAGAGAAGCAAGCTCCAGGTATTGCATTGTTTTAAATTAGGATATTTGTGTTCTCACTTACCTTATTTGAGGCCTGGACTCCTTAAAGAAGAAAATCTAAATTCAAGAGAATACTTTAACTTATCTTAACAGATTCATCCACTCATTCTAAAAACATGTTTGTAGATTAGAGGGAGTTTAAATTTAGGTTTTGTTTTTCAACATCTGAAACATTTGAAATCCCCCAATTGCAATTTTAAAATTTTCCTCTACATCATAGGTCTCAAACTCTATTCCTGGAGAGCCTCAGCTCTGCACAGTTTTGCTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa963
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000065433 Essential Splice Site 750 1507 17 31
Genomic Location (Zv9):
Chromosome 6 (position 10964178)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 10817804
GRCz11 6 11053231
KASP Assay ID:
554-0868.1 (used for ordering genotyping assays)
KASP Sequence:
CAGATCTGGACAATCTACCTGCAGGAGATGCCACTGAGATTGGAGAGAAG[G/A]TGAGACACCTATGCTTTACCCAAAGTAGAGTAATGAGCTAAAGTTATATT
Long Flanking Sequence:
CTTTGAAAGGCATGTCATGATTGTACAGTAGATTACCTTAATGACATTCTTGTTTTAAAATATTATATATATATATATATATATATATATATATATATAATGCAGAGGTGTACTTACATGCAGATGGGGTACAGTGGTCTGACAACAATGTGAATGCATTCAATGTAAATCTGTAAATAAACAAGCCATTTTAACAATTAGAAAAAGTTCCAAAGCAGTAAAATGCTATTTCCATTTTTTCATTATTTAAAAGGGACTAATCACATTCCAAAATTGTATTAGTTGATTTTTTTAATAGTATTTCTTTGCTTTTGTCTATTTAGGGCTCCATTGCCTACGTACCCCAGCAAGCTTGGATCCAAAACGCCAGTCTGCAGGATAACATTCTGTTTGGACGGGAAAAAAAAGAAAGCTGGTACCAGCGAGTGCTGGAGGCCTGTGCCCTGTTGCCAGATCTGGACAATCTACCTGCAGGAGATGCCACTGAGATTGGAGAGAAG[G/A]TGAGACACCTATGCTTTACCCAAAGTAGAGTAATGAGCTAAAGTTATATTATAGAATGATAACGCGGCAAAATACGCAAAATCGAAGATTCCCGGAAATATTGCCTGAGTCACAGAGAGAAAGTGACACACATTTATCATTTTACTGCCTTCCGAGTAACCTGAGGGTCCGTCCTGAATGGATAGTAAAAATAAAAAGGGATATCAGACCTCATTTTGAGCTAAGGGAAATGGCACTAGTTAGCTAGTGTTTTCTTTCCTAAACACACGTTTTAGATGCCATTTATTAAACTCAAGTTAATAAACTGATTCTTTCACTATATTAGGCTTATCAAGATACTGAATTTCAGTACTGAAATAAAAAAAAAAAACATAAATTTTCCGTTAACATTTAAGCACCGCTGATTTGCCATAGTATTCACCAGTGCTCAACGGAAATGACTGTGATTGGCCATAAAGGTCATCAGTTCACCGATCTTCATCGAGTGCAAACACAAACAA
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa2285
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000065433 Nonsense 758 1507 18 31
Genomic Location (Zv9):
Chromosome 6 (position 10965677)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 10819303
GRCz11 6 11054730
KASP Assay ID:
554-2533.1 (used for ordering genotyping assays)
KASP Sequence:
TTTAATCATRARCAAAATTGTTTTGCCAGGGTTTAAATTTGTCTGGAGGA[C/T]AGAAACAGAGGGTGAGCCTGGCACGYGCTGTTTACAGGAAAGGTGACGTG
Long Flanking Sequence:
TCCTCAACGCAGCCTCACTTTCATTTTTTAAAATGGCAGCCAAGTGAAATAGGCGTATTCGGTTGTATGCAGAAGAATACTTAAGTGAATATAAAAACCTATTTCAGTCATTTAGAGATACAAGTAATCTGCAAGCGAACACATAATTTCTGCTCGGCTCCTGCTGATTCTGAATCTAATGATTTTGCCTGCTCAAATTTTAAATAGTCTGGTTCAGTGTTTGCTATATAGTTCCTCTGAAACCCTCCAGCTCCGCCTCGCTAAATATCATGCCACAAGATTTATAGCTATATGCCTGTTCATGCAGCTGCAGTATACTGTAGATTTTCAGAGCAATCTGTGTATCTATTGGCCGTGACAAGTCTGTTCTTGCTCTGTAGCAGTAGTGTGTAGCAGATAGTCCACTCAAACCAAGTACATCTTTCTTCCATTCCACTTGGAGAGTTTTGATTTAATCATGAACAAAATTGTTTTGCCAGGGTTTAAATTTGTCTGGAGGA[C/T]AGAAACAGAGGGTGAGCCTGGCACGCGCTGTTTACAGGAAAGGTGACGTGTATCTGCTTGATGATCCCCTGTCTGCTGTGGATGCACACGTCGGTCAGCACATTTTCAACAAAGTCATTGGGCCCAAAGGCATACTGAGAGACAAGGTGACTAATCTAGCAGGGTTCATTCGACAGGCGGGGTGGGTCATTTTCTTATTTCTCAGCAATTTCAAAATCTAACATTCACATTTTATTTAAAAGACACGAGTTTTGGTAACCCATGGCATGAGCTTCCTGCCTCAGGCAGACTTGATCTTGGTTCTGGTGGATGGGGAGATCAGTGAGAGAGGCTCATATCAAGAACTTCTGAACCGCAATGGGGCTTTTGCTGATTTCATCCACACGTTTGCAAACTCCGAAAGGAAAGAGTGCTTTTCGGAGGCCCTTCAAAGAGGTAATATTGCTACGCTGTGTGATTGTGTGAGGCATTCACCATTAAATAATGGACTTCTTATATAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40643
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000065433 Essential Splice Site 897 1507 20 31
Genomic Location (Zv9):
Chromosome 6 (position 10966367)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 10819993
GRCz11 6 11055420
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACTGACTACATGCCGTTTTCGAGGGATCTATCTCAAGAGCAGTTAATCGG[G/C]TATGGAATTTTATATTTGCTAATGCATTGCTAACAAACACTTTAATGACA
Long Flanking Sequence:
TTTTCTTATTTCTCAGCAATTTCAAAATCTAACATTCACATTTTATTTAAAAGACACGAGTTTTGGTAACCCATGGCATGAGCTTCCTGCCTCAGGCAGACTTGATCTTGGTTCTGGTGGATGGGGAGATCAGTGAGAGAGGCTCATATCAAGAACTTCTGAACCGCAATGGGGCTTTTGCTGATTTCATCCACACGTTTGCAAACTCCGAAAGGAAAGAGTGCTTTTCGGAGGCCCTTCAAAGAGGTAATATTGCTACGCTGTGTGATTGTGTGAGGCATTCACCATTAAATAATGGACTTCTTATATAAGTTTGAACACTGGTGTTAAAAGCTGATCTTCTCTGTGTTGCTTTAATGTTAAAAAAACCCATGGAAATAGAATTATTGATCATTTTTATTTTTAATTCATATACTTGCAGGCTCCAGAAAGTCCGTAAGATTGAGTGTTACTGACTACATGCCGTTTTCGAGGGATCTATCTCAAGAGCAGTTAATCGG[G/C]TATGGAATTTTATATTTGCTAATGCATTGCTAACAAACACTTTAATGACATAATTACTTTAAATGATCCAGAAAATTGAAACTAAATCTTATATTTATGCATGATGACTGTGGTCAAAGTTGGGTGACCAGTCTCTGGATTATGACATTGCAAATAGTTTTTAAAACACAATGTAATCAGATCTGAAAATGATCCTAAAGATGAGGAACGCCTCATTGAGTGGGGTTAAGTTCAACTGGTGGTCTAATCATATGCCTTCCTTCACATTTTAAACCATTTGATCTTGGCATTTTTATTTTTGACCATGGGATACACACTAGGTTAGATTTTAAATAATTGTTGCCAAACATATAATATGCCAGAAAAATATTAATCATTACATTAAAGATCCGACCATAGACTCTTAAGAATTAAATACAAACAGCAAGCTTGATTTTTTTGGCCAGGAGGTATGTTTGAGCTTAACCATGGCTCTTACTTTAGGCATTAAACCAAATCTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31502
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000065433 Nonsense 971 1507 22 31
Genomic Location (Zv9):
Chromosome 6 (position 10967284)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 10820910
GRCz11 6 11056337
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTATTTCTCTACGCCTTCCAACAAGCAGCGTCTCTGTCAAATAATTACTG[G/A]TTGAGCTTGTGGGCCGACCAGCCTGTGATCAACGGCACTCAATTAAACAC
Long Flanking Sequence:
ACAAACAGCAAGCTTGATTTTTTTGGCCAGGAGGTATGTTTGAGCTTAACCATGGCTCTTACTTTAGGCATTAAACCAAATCTGACTTCAGTGTTACTCTCTATAGTACTAATCACACTCAGCTGTATCAGTTCTTCACTAAATATCCTAAAAGTGTCAAGACTTAAATGATTTAAACCTCTTTCAGTGGTGACACAAACAGCATTGCTATTGAACCACTACCTGATTCTGATGAAGACCACATCCCAGAGGACCTGGGGAAACTTACGAAGGTTGACAAAGCACGGATAGGCAGAGTAAGATTTATTATTAAATTCTTTTTCTTCTCAAAATATTTTTGTTTTATTTAATCAAATGTTTGACTTTGTCTTCTTTCTGTCCCAAAAGGTCAAACTTGAGATGTACATCGAATACTTCCGTACCATTGGTTTACCTTTAATAATTTCCATAGTATTTCTCTACGCCTTCCAACAAGCAGCGTCTCTGTCAAATAATTACTG[G/A]TTGAGCTTGTGGGCCGACCAGCCTGTGATCAACGGCACTCAATTAAACACAGATCTGAAATTGGGAGTCTATGGAGCTCTCGGCTTTGCACAAGGTGAGTAAAGTTTTACCGCTTTACCACAAACAACTTCAGTTGATGTAAGTCAGTGTCAGATGTAACTAATTCATCATTTGTTGTATGTAGGAATTTCCATATTTGGTACCACTGTGGCCATCTCATTAGGGTGCATCATTGCCTCTCGTCATCTTCACTTGGACCTTCTGAACAATGTTCTCCACTCACCCATGTCGTTCTTTGAATCCACTCCCAGCGGCAACCTCCTCAATCGTTTTGCTAAAGAGATAGACGCCATAGACAATATGATTCCAGATGGGCTAAAGATGATGCTAAGTTACTTCTTCAAACTCACAGAAGTCTGTATCATTGTGTTGATGGCCACTCCTTTCGCTGCAGTTATCATCCTCCCTATGGTTTTCCTCTATGGTTTCATACAGGTATG
Associated Phenotype:
Not determined