Busch Lab

ZMP

cep170l

Ensembl ID:
ENSDARG00000058892
ZFIN ID:
ZDB-GENE-050309-106
Description:
Novel protein similar to vertebrate centrosomal protein 170kDa (CEP170) [Source:UniProtKB/TrEMBL;Acc
Human Orthologue:
CEP170
Human Description:
centrosomal protein 170kDa [Source:HGNC Symbol;Acc:28920]
Mouse Orthologue:
Cep170
Mouse Description:
centrosomal protein 170 Gene [Source:MGI Symbol;Acc:MGI:1918348]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa15942 Essential Splice Site Available for shipment Available now
sa45242 Nonsense Mutation detected in F1 DNA Not yet available
sa33798 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa15942
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081841 Essential Splice Site 485 1297 8 18
ENSDART00000137642 Essential Splice Site 485 1296 9 19

The following transcripts of ENSDARG00000058892 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 6389432)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 6315448
GRCz11 6 6472617
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGGAAAATGGCAGTGCTGAGGTKGAAGAGGCCAGGCGTATGAYTGATAAG[G/A]TAAACCTGCAGAAGCATAAGATTTWGTTGTTGTTTGTGTGTATGTGTGAT
Long Flanking Sequence:
TTCACACAACTGTATTTTTAATAAACGTTAAGCAAGTCTTTGACCTATAAAAGATGGAATGCCTTTTAAATGTCACGGGCTCTACTCCTTAATGTTTGTCCCATTCTTTCTCAGGCAGTAAGCATGAGGATGGCACACAGAGTGACACAGAGAATGCACTGGGAGAGCAACTCAGTAGCCGCAGGACATTTCTGCAGGAGCGCTACAAAGGAAGGCAGGCCGTGCAGAGGACAGAAGGCCCTGTCTGTGGGAGGGAGGATCTCTTCCAGTACAAACCATCATCTGCAGCTAGAAAGATGGCACCAATAGGGGGGGAAGTTAGCAAAAAATCTAGCCGTTCTTCACCACAGAAGACCAACGTGCCTAGAGAGCAAAGCACTGGGTCTCAAGAGACTCCGAATAGAGGGCATATAGATGACCAAAGCGACAGAGGGACCTACACCATCGAGCTGGAAAATGGCAGTGCTGAGGTGGAAGAGGCCAGGCGTATGATTGATAAG[G/A]TAAACCTGCAGAAGCATAAGATTTAGTTGTTGTTTGTGTGTATGTGTGATACAGAAAATTGTTAGATCTGGATGTGCAGATGATCAATCTGATTGGGTTTAGGTTTTTGGTGTGGAAGATAACCAAGCACTGACAAAGCTGCGTTTTCCAAAACACCAGAAAGATAGAGGAACCATATGTCCAAGATCTGGAGCCATGGAAACCAGACAAACTGGCTATGTTGGTGCAGAGGTATTGTTTATCAGCATAAATTGCTATATATACAATGAATATCCATTATGTACAAAAGTTTCCAAACTGTACCAATCATTTACTTCAGTCAATTTCCCTTTTAAAAGGCACTACCAGATGACTTGGTTGTAGTTGGTGGTCCAAGGTGGGTCTCACAGTGGGCTAGTCTAGCTGCAAGTCATATACGAACTGACCCTGAGGGGTCCGGAGCTGAACCCACCATGCTTTCCACAGATGAAAAAGGTTAAAGGGTTTGCAAATTTCTCAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa45242
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081841 Nonsense 924 1297 11 18
ENSDART00000137642 Nonsense 923 1296 12 19

The following transcripts of ENSDARG00000058892 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 6387829)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 6313845
GRCz11 6 6471014
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGCGGGCACGATTAGGTGAAACTTCTGAAACTGATCTTGCTGATGTTGAT[C/T]GAATGTCTGTTGCATCAGAAGCATCTACTGCCAGCTCTGCATCAAGACCT
Long Flanking Sequence:
AAACCACTTTATCAGACCTAGCAGATCCCCCAAGCTACTCCCTGGAGGGGTCTGCCTCACCCGAATCAGACATTGATACAACAAGTACAGTCAGCCAAGCTGGGGGAGAAGGAGGTCGTAAGACAGCCCAAAAGAAGCGATTAGCTGGACGTGAAACAACAAATAAAAACGCCGGTGCTACAGAAAGGAAGGGCAAAGCTCAGCCCTCTGGTTCTGCTGGTTCCAGAGCTTGGACATCTCTTGACCTGACAGATGATGACTTGAGCTCTTCCCTTGCCCAGGATGCTACTTCAGTAAAGCGACCCCAGGGTAGGGGTCAAAATATCAGCTCTAAGGCTGAGCAAACAAGTGGCAAGACCAAAGGACCAAAGACAAGTGTAACTCCTGCAGCCCCCACCTCTAAACCAACAACACTTCCCCGCCCTCGACCGACACGGGCTTCCATTCTTCGGCGGGCACGATTAGGTGAAACTTCTGAAACTGATCTTGCTGATGTTGAT[C/T]GAATGTCTGTTGCATCAGAAGCATCTACTGCCAGCTCTGCATCAAGACCTTCAGCTGGACGCAGGACCCTCTCTCGGATTGAAGCTCTTGCTCAGCCAAGAAGACCAAGAGTGTGCTCTCCTTCAGCTCGGAGTGACTCAGAGGCAACATCAGGCAAGATCAGGGGCTTTGCCCCACGTCCTGCCCCTGAGAGCGCACTTCGGCTTGGTCTCCGCTCTACTGGAGTCTCGACAACTGCAGCAGTCCCCAGAGCGAGAGCTAACAGTGCTTCCAAATTGCCTGATAAATGTCCTGGTACTCTCCATGTTCAAAGTACACCTGCAGGTCAGAACCTTGAGAAAGATAGTACTAGAAAAGATAATTCTCTGAAAATATTTCCACTTAAATGTTTTTGTGTTGTAGCTGGGGGAAGGTGGCGCCGGGTGCCGATTGAATATGCTTCTACCTCAGAAGATGAGTATGGCTCCAATCGACACCCCTCTCACCACACACGCCCACGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33798
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000081841 Essential Splice Site 1256 1297 None 18
ENSDART00000137642 Essential Splice Site 1255 1296 None 19

The following transcripts of ENSDARG00000058892 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 6380467)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 6306483
GRCz11 6 6463652
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TAAGTTTTGGCACTTTTTATTCATTTTTTTTTTTTCATTTGATCACCCTC[A/G]GGAGATTTCCTCCATACTACAGAATCTGAAGAGAGTGGAGCGACAGCTGC
Long Flanking Sequence:
TATCACTTTTGAATGACCAAAGAGTAATGATAATTTTCCTATCTAAAGCTTGACTTTCTGTAGTTACATTGCGTACTAAGACTGATGGAAAATGAAAAGTTGCAATTTTCTAAGTCAATATGGGTAGGAACTTTTAGCATAGCTTAGCATAGATCATTGAATCAGAATAGACCATTAGCTTATCACTTTAAAATGACCAAAGAGTAATGATAATTTACTTATCTAAAGCTTTACTCTTCTGTAGTTACATTGCTACTAAGACCGACGGAAAATTAAAAGTTGCTATTTTCTAAGTTAATATGGGTAGGTACTTTTAGCATAGTGTAGCATAAATTGCTGAATTAGATTAGCCCTTTAGCATCTAGATAAAATTTTTTTACAGAGTTTCGTTAACTTTCCTATTTAAAGCATGACTTAATTTCTCATTAAATTAACTGTAAAGGTCATTTCTAAGTTTTGGCACTTTTTATTCATTTTTTTTTTTTCATTTGATCACCCTC[A/G]GGAGATTTCCTCCATACTACAGAATCTGAAGAGAGTGGAGCGACAGCTGCTCGGTAAGCAGAACTGAGATATTCTTGACTGTTGTTATGGATTTAATGTTTGCTTTGCAACATGCAGCATTTTAATGCAACTTTTTGAACTAGCATGAAGTGGATTTATTATTATCTTTATTTATTTTTAAAGTGCAAGCTTTAAAGCATGGATATGTGTGATGTTCAGATTTAGTGTGTGGTGCCCAGTTTTTCTTTGTGACCGTTTACAAAGTCTGAGTTGCCTGGTGCTTTAAAATCTGTTCAGTTTTTAAAAGTCGTGCCACTTGTTCCAGTTTTGAGAATATCACCATTACCAAGCCAAAAAGTTTCTGAACATTTCAAACCTGTTTAACAATTTAATACTTTTAATACGCTAGCTTGGGTTTTTGGAAGAAGTCTCATACTCATCAAGACTGCATTTATTTAAAGTAAACACAATAATAATGTGAAATATTATTTGAACAATAT
Associated Phenotype:
Not determined