Busch Lab

ZMP

dlg4

Ensembl ID:
ENSDARG00000041926
Human Orthologue:
DLG4
Human Description:
discs, large homolog 4 (Drosophila) [Source:HGNC Symbol;Acc:2903]
Mouse Orthologue:
Dlg4
Mouse Description:
discs, large homolog 4 (Drosophila) Gene [Source:MGI Symbol;Acc:MGI:1277959]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa33773 Nonsense Mutation detected in F1 DNA Not yet available
sa14583 Nonsense Available for shipment Available now
sa31490 Essential Splice Site Available for shipment Available now
sa33772 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa33773
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000048432 Nonsense 170 691 5 20
Genomic Location (Zv9):
Chromosome 5 (position 71459827)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 67785513
GRCz11 5 68557558
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCATTTATGTCACCAAAATCATCGAAGGAGGAGCGGCTCATAAAGACGGA[C/T]GACTACAGATTGGAGACAAGATTCTGGCGGTATGATGACACACACATCAC
Long Flanking Sequence:
TGACTGTCCCGCTGTATTTAGTGAAATCCGTCAGTTACTGTCTGAGCGCCTGCAGCTTCTGACAGGTGTCACTTCTCAATTCTGATGTAAAAAGCCGGCTTAATAACATCTCATTTCTCTCCCGGACCCATTTGTCTGTCAGAGTGAATGACAGTATTCTGTTCGTGAATGACGTGGACGTTCGGGAGGTGACCCACAGTCAGGCGGTGGAGGCGCTGAAGGAGGCCGGAGCCATCGTCAGACTCTATGTGTTACGCAGAAAACCCATCGCTGAGAAAGTCACCGAACTCAAGCTCATCAAAGGGCCAAAAGGTATCGAGAAGCAACACGTGATTAAAAAACTGTCAAAGAAAACGCTGTCTTCATCTTTACATTTGTGTGTGTGTGTGTCAGGGCTAGGCTTCAGTATAGCTGGTGGTGTGGGGAACCAGCACATCCCCGGAGACAACAGCATTTATGTCACCAAAATCATCGAAGGAGGAGCGGCTCATAAAGACGGA[C/T]GACTACAGATTGGAGACAAGATTCTGGCGGTATGATGACACACACATCACTGATGAGGACTAATACACAGACAGACTGGTAGGAGTTATTGCTGAGTGAGATTCGAGCATTATCCTCATATAGCTGTGTATCTTTGGCTCATTCTGGCTCTTCAATGCTGCCACCTGCTGGTTGCATGTGTAGTGTTCAGTTTGAGTGTAAACCTGGATCAGAAAAGCAGTCGTGGGATTTAGAGTCAGTTTTTGGAGATTTAGATTCATGCCTTATCTAAAAGCTGATTAAATAAGCTTTTTAATGATTGTGTTTTCAATCGTTTGTTAATTGTCATGTATAGAGGATTTACAAAGCATGAATAGTCCTAACTTTAGGACACAAAACTGGATGAAGTTGAGTTTATAAAGCATTTATTACATACAAAGTCACCAATAAATGCCTGAATAATCAGTTATATAAATGTTCAGTTAAATAGTTTATTAATTATTTGCTTACGCATTCTGAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14583
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000048432 Nonsense 266 691 7 20
Genomic Location (Zv9):
Chromosome 5 (position 71454301)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 67779987
GRCz11 5 68552032
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGCCCTCACTCCCACCTCACCGAGCCGCTTTTCTCCTGTGCTGCATGGCT[T/A]GTTGGGAGACGACGACTTACCCAGGTAAAGCTTTMGGATAACTGGAAGAY
Long Flanking Sequence:
TTTTAAACACTTTCAAAAGTGTTTTATGAAAATTCAAAGGGTTTTCTTTAAAATGATACCAATTTTTTGCATTTACACCTCTGCATGTGGATTTGGGAAGCTTTTAAATTTAGGTAGGCAAAATCCAGGCGGAAATCACAAAATAGCAGCAGAGTTTAACTGGTTAAACAGAAACTGGGGGAAAAAATAAACATTAATTCTAATATTCTAATGCTAATAATTCTGACTTCAACTGCACACTGCCTGACAAAAGTCTTGTCGCCTTTCCAAGTTTTAGAAACAACAAATAATAAGTTGATTATTTGGTATCAGAAGTGACTTCTGTGAAAGGCAAAGGCCTCTTGATTACAGCTTTGTCGATGTTTGTGGATGTTTTCCCTGTTCAGCTTACTCTCCGCATCTGGACACAGACCTTGGACATCCAAACTTCCTGGCCTCGGATTACCCACAAGCCCTCACTCCCACCTCACCGAGCCGCTTTTCTCCTGTGCTGCATGGCT[T/A]GTTGGGAGACGACGACTTACCCAGGTAAAGCTTTAGGATAACTGGAAGACGATTCAGCAGTACTCACACTTTCTATGTGGATTTTTATTATTATTTAAAATCGACGGATGAATGGACGGACAGACAGACAGACAGACAGACAGGATAGACTGATAGACAGACAACACAGATAGATAGTTAGACAGACAGGCTAGATAGGTAGACAGATAGACAGATGGGATAGATGCACAAAAAGATAGATGCATGGATGGACGGACAGACAGACAGACAGACAGACAGATAGACAGACGTTATAGATAGACAAATAGATAGATGCATGGATGGATGAATAGACAGATAGACAGACAGTATATCTAGACAGACAAGATAGGTACTGTAGATAGATAGATAGACATGGTAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGACAGACAGACAGACAGACAGACAGACAGACAGACAGTCTAGATAGATAGATAGATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31490
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000048432 Essential Splice Site 454 691 11 20
Genomic Location (Zv9):
Chromosome 5 (position 71446823)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 67772509
GRCz11 5 68544554
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGCAGAGTCAGTCCTCAGGGGGACGAGGAGGAGGTCGGCTTCATCCCCA[G/T]CAAGAGGAGGTTTGTGTGTGTGTGTGTGTGCGTGTGTGTCTGTCTGTGTT
Long Flanking Sequence:
ATATTAAAAACTGCTTTTATTCTAACCAAAATAAAACAAATCAGACTTTCTCCAGAAGAAAAAAAATTATAGGAAATACTGTGAAAAATTTCTTGCTCTGTTAAACATCATTTGAGAAATATATAAAAGTCACAGAAGGATGAATAATGCTGACACACTGCATGCTTTTTAAACAGGCGACAGGAGAGCTGCATGCTGAACACTCAGTCAATGAGTGAGAATGAGAATGGGCAGAAATGAAAGGCCTGTCTCTGCTTTCAGTGTGACTCTTTGATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCTCCGCAGGGCTCTGTTTGACTATGATAAGACTGCAGACTGTGGTTTTCTGAGTCAGGCGGTGGGCTTCAGGTTTGGGGATGTGCTGCATGTGCTGGACTGTGGAGATGAGGAGTGGTGGCAGGCCTGCAGAGTCAGTCCTCAGGGGGACGAGGAGGAGGTCGGCTTCATCCCCA[G/T]CAAGAGGAGGTTTGTGTGTGTGTGTGTGTGCGTGTGTGTCTGTCTGTGTTTGCATCTGTATATATTTGTGTGTGTGTTTGTGTCTATGTGTCAGTGTGCATTTGTGTGTGTTTGTGTGTCTCTGTGTGCATTTATATTGTGTGTGTGTGTCTGCGTCTGAACGCGTGTGTGTGTGTGTATGTGTGTGTGTGTCTTTCTCTCCTCTGTTGTCCTTCAACAAAATCATATTGATGCATCTTGCAGAAGTTTTCAGCTTCACCCTCTCTCTCGTTCACACACACACTGTCAGAAGGACGCGCTCCAGAGAGGTTTATACACACACAAACACACACTCTCTTTCTCTCTCTCTGCTGTCACTTTAACAAACAGTTTAGGGTGAAACACTTGACTAAAGCTCTACTGACAGCGTGTGTAATGTGAATAAAAATCCCTCGCCCCTCACATCACGAAGATACAGATTACACTGTCATTTTAATCTTTAAATCTGCATTTATTTGTGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33772
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000048432 Essential Splice Site 531 691 17 20
Genomic Location (Zv9):
Chromosome 5 (position 71435493)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 67761179
GRCz11 5 68533224
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCACTACACGTTTGAATAGAATCACGAGATGATATCTTTACTGTTCTTC[A/G]GATACGACACGACCCAAGCGGGAGTATGAGGTGGATGGACGGGACTACCA
Long Flanking Sequence:
GAGCTACGCATCGATGAATTTGCTCTTCAGTGTTTGAACTCTCAGAAATGATTAAATCACACTGAACTGAGCTAAACTGAACTGAACTGAACTTAAACACTAAAACCTGAACCACACTGTTCCAGTTACTATGACCATTTATGTGAAGCTGCTTTGACACAATCTACATTGTAAAAGCGCTATACAAATAAAGCTGAATTGAATTGAATTGAATTGAAGTTATTATTATTATTATAATTTTGAGGAAATAAATGAATTTAATCCATTTTGGAGTAAGACTGTAACATAAAAAATGTGGAAAAAGTGAAGCGCTATCAACACTTTCCGGATGGACTGTATATGCTGAGCACTGTACTGATCAAACCTTTATGTACAAATTTCTCATTTTGACTGTGATGAAATAACGTGCACCTTTTGTAAAGCTGCTTCAGTACAATAATTATTGTGAAAAGCACTACACGTTTGAATAGAATCACGAGATGATATCTTTACTGTTCTTC[A/G]GATACGACACGACCCAAGCGGGAGTATGAGGTGGATGGACGGGACTACCATTTCGTGTCTTCGAGGGAACAGATGGAGAAGGACATCCAGAACCATCGCTTCATTGAGGCGGGCCAGTACAACAGCCACCTGTACGGCACCAGCGTTCAGAGCGTCCGAGAGGTGGCAGAACAGGTTAGGGATCAATACTGTCAGTATGTGTATCAAATTGATCAAACCTTAATAATGTTTAGTTAAAGTCAAAATGATTAGCACTCCTGTGAAATTTGTATTCTTTTTCAAATATTTATCAGAGAGAGGTGATTTTTATCAAAGAGAAGGGCACCTATTATGCAAAAATCCCTTTTATAAGCGGTTTAAACACAGTTGTGTGGTAACAGTGTGTGAATATAGTCAGCTTCAAATGGTAAAAATGTGTTAGTTTTATTCATTATAATCGCACTTGATAGAAACAGCCTGCAGAGACACTTTAATAGACATTCTCCCGATGTATGTGTCAT
Associated Phenotype:
Not determined