Busch Lab

ZMP

iqgap2

Ensembl ID:
ENSDARG00000060010
ZFIN ID:
ZDB-GENE-030131-2878
Description:
IQ motif containing GTPase activating protein 2 [Source:RefSeq peptide;Acc:NP_001121812]
Human Orthologue:
IQGAP2
Human Description:
IQ motif containing GTPase activating protein 2 [Source:HGNC Symbol;Acc:6111]
Mouse Orthologue:
Iqgap2
Mouse Description:
IQ motif containing GTPase activating protein 2 Gene [Source:MGI Symbol;Acc:MGI:2449975]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa38499 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa1554 Nonsense Available for shipment Available now
sa33696 Nonsense Mutation detected in F1 DNA Not yet available
sa40546 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa38499
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000084069 Essential Splice Site 112 1526 3 34
ENSDART00000138055 Essential Splice Site 139 1680 4 38
Genomic Location (Zv9):
Chromosome 5 (position 47725806)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 45514546
GRCz11 5 46114699
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TAACACCGTGCAGTGGCTCAGAGCCATGGAGTCCATTGGTTTGCCCAAGG[T/C]GAGGCCCACACATACACACACAGACACACACACCTCTTTGAAGATAATAC
Long Flanking Sequence:
TGTTCTATAGTTATTCGTTCATTCGTTTTCTTGTCGGCTTAATCCCTTTATTAATCCAGGGTTGCCACAGCTGAATGAAGCACCAACATATCCAGCACGTTTTTACGCCTCGAATGCCCTTCCAGCCGCAACCCATCTCCGGGAAAGTGTTCTATAGTGTTTGCTAATAATAAAAATAAAAAAAATTTTAAATACTGAAATACCTCAAAATAAATAGTAAAAATAATACTTTAAATAGTATTGTGCTTTTCTAATTCCTTCCAATTGCTTATTTACCTCGCATATTTCTGTTGCATACATAACAGACTAAACACAGAGCATTTTCAAAGCAGCTTTATATATAATTCTGTTTTAATTAAAATTGTGCCGTCATGTTTTATTTATTCGTATTTATTCGTGTTTTGTTTTGCACTTTCTCCAGCTCTCAGGACTTCATTTCAGACACACTGATAACACCGTGCAGTGGCTCAGAGCCATGGAGTCCATTGGTTTGCCCAAGG[T/C]GAGGCCCACACATACACACACAGACACACACACCTCTTTGAAGATAATACTATGTTTATTGCACTTACACTCAAAGAAATCAAGCCGTGGTTCAGAATTATGTCCTGTTTGCTTTATGTGCCCATTTGTTGGTTTGGAAAGGAGTGTGAATAATTAATTTACAACTGTCATAAGAAGAATGCATAAGCCTATTACTGAACATTTACTCTTGGTATAAGTTATCAATCATTTGGTTTATGTTTCTTACCCTTTCGCTCAAGAGCAGAAAAAACGAAGAAAGGCATCCTCCAGGTATACAGCGGAAACCTGGTGCAGTGCACAGCGCATTACACAAAGCCACAGAATCAAAATGTCGCTATGTTTACATATATGGTAAAATTTGGCAAAACCTAATATGACACCAAATTATACACTGCCTGACAAAAGTCTTGTTGTCAATCTCAGTTTTAAGAGTAGAAAATAATAACTTCTAGTTAATCATTTGGAAAAGTGTCAGAAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1554
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000084069 Nonsense 719 1526 18 34
ENSDART00000138055 Nonsense 746 1680 19 38
Genomic Location (Zv9):
Chromosome 5 (position 47773076)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 45561816
GRCz11 5 46161969
KASP Assay ID:
554-1497.1 (used for ordering genotyping assays)
KASP Sequence:
ATGCNTTTTTTTTATAAATAGAATGTTTTGAGCAGTGTAACAGCGGAGTA[T/G]AATAGAGAGCAGCTGTGGTTGGCCAATGAGCCGTTTATCATCCAGCTGCA
Long Flanking Sequence:
AACGCGCCCGACAACACCGCTCTTCAGTACGTGCGCGACAACAACAACACCCCCACCCCACTCCTCAAAAAATGTATCCTGCACATGCCCTTTGGACGGTCTCTGCATGGGCCTGCATTATCATATTAGTTGAAAATATTCCTTTCAAACTTCATCTAAAACCTTTACTGATCATTTTATTTTAGACTGAACCAAATGTTTATATTTTCATACTTATATTATGCTTCTGTTTTCCGTAGGCACCAGTGGCAGTTCATGGGTGCAACACAAGATCAAGGATAAATATGATTACTTCTACAACATTGAATGCAAAGAAGGCACGTGGGTTGAGCCTGAACATTTTGTCCATGACAGTTCACAGCTCAGCAGAGAGGATATCCAGGTATGACTTTAGCACAGAAATTGTGTTGAGTTGTGTTGACTTGAATGAAATGAGCTGTATTTCAGTTGATGCTTTTTTTTTATAAATAGAATGTTTTGAGCAGTGTAACAGCGGAGTA[T/G]AATAGAGAGCAGCTGTGGTTGGCCAATGAGCCGTTTATCATCCAGCTGCAGGCTCTGATTCGTGGATATCTGGTGAGGCGGGCACATCAGGACAGACTGGAGTACCTGCGAAAACAAGAGCCAAGTGTCATCAAACTACAGGTGCTTAAGTGTATTATATTAGAGTTGACTCATAGCCTTTTGATTTACCTTGTGATTTGTTTACATTTTACTGTTCACATTTTTATGTTATTACCAATTACACAAAAAAAGTACAATAATTTGTCACTGTAAATTATTCAGAACGTTTTCATAGAACGCAAAATTACCCTTTATGCTTTGCGTGTATGCATTAGAAAGATGCTTCCAGCTTCCGCTTGATGCATATAAAGATTTACATTTGGACAGATTTGAAAAAAAAAATGTTTTAATGTATTTTACCAGAGGGGTCTGGATGCAGACCTAGTGCAGCAGATGCAATCTGAGCTGCATGCAATGCTTTTGAATGGGCTCACCTAACC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33696
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000084069 Nonsense 1178 1526 28 34
ENSDART00000138055 Nonsense 1204 1680 29 38
Genomic Location (Zv9):
Chromosome 5 (position 47785679)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 45574419
GRCz11 5 46174572
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATTGCTGTCTTCTTCCCTCAGATTGTAGGGACTCTTCTGTATTACCGCTA[C/A]ATGAATCCTGCCATTGTGGCTCCAGACGGCTTTGACATCATTGACATGAC
Long Flanking Sequence:
GGTGCCCTTTAAAGCTTGACTCTATAGTTTCAATGTTTACTAAGACTGGTGGAAAATGAAAAGTTATTATGCCAGAATGTCATATTAGCCTAGAAAATATCAATTTGTTTTATTTTCTGTCAGACATAATGCAATAGATACTAAATCAAAACTCTTTTTTTAAAATTCTTTTTAAGTGAGATGCTAATGTTAAAATTTGATTCAATGATTTATACTAAGCTAAAAGTGCTCCTGCTAGAAAAAGAGATCAGCTGAATGGACTAAAAACGGTTAAAACTCATCTGTTTAGTTTTAGTTAAGTTGTAAAATAGGCACATTTTTCAAAAAAGTGTTAGTAAAGTTTAAATGTAGATGTCATTTCTTGACACATCAAACCAAGACAGAATAAGGACCAAATCACCTTTTGACTCAACATTTCAAAAACCAAGATATAATAAGCATAATATAATTATTGCTGTCTTCTTCCCTCAGATTGTAGGGACTCTTCTGTATTACCGCTA[C/A]ATGAATCCTGCCATTGTGGCTCCAGACGGCTTTGACATCATTGACATGACAGCGGGAGGGCAGGTTCATTCGGAGCAGAGGAGGAATTTGGCGTCCGTGGCTAAGATGCTTCAGCATGCAGCTGCAAACAAACTATTTGAGGACGAGAGCGACCACCTCACTCCCATGAACAGCTACATCTCCCAGACCTACCAGAAATTCAGGTGAGGAGAACAGAGCTTCTCATCAGTATCCGTCTTTACATCAAATGTAGAGAATTTTCTTTATGTGCAAATAAAGCATCGTTTCTATTCCAAGTGTTTAACAGAATAAAAGGGTCAGGCGGGTAATCCATGTTAGCCCTTTTTTCTTCCACAGGAATTTTTTATAGGTATACAGTTTATTCCTATTTCGAGGCTTTGTTTTTATGCAATAAAACATGGTATAGGAATAGGTTAATGGAAGGTAGGAGGGCATATTCCTGGATCAAGATCTATGTTTATCCTGGAACAACATTACAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40546
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000084069 Essential Splice Site 1246 1526 28 34
ENSDART00000138055 Essential Splice Site 1272 1680 29 38
Genomic Location (Zv9):
Chromosome 5 (position 47785884)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 45574624
GRCz11 5 46174777
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACCTCACTCCCATGAACAGCTACATCTCCCAGACCTACCAGAAATTCAGG[T/C]GAGGAGAACAGAGCTTCTCATCAGTATCCGTCTTTACATCAAATGTAGAG
Long Flanking Sequence:
TGATTTATACTAAGCTAAAAGTGCTCCTGCTAGAAAAAGAGATCAGCTGAATGGACTAAAAACGGTTAAAACTCATCTGTTTAGTTTTAGTTAAGTTGTAAAATAGGCACATTTTTCAAAAAAGTGTTAGTAAAGTTTAAATGTAGATGTCATTTCTTGACACATCAAACCAAGACAGAATAAGGACCAAATCACCTTTTGACTCAACATTTCAAAAACCAAGATATAATAAGCATAATATAATTATTGCTGTCTTCTTCCCTCAGATTGTAGGGACTCTTCTGTATTACCGCTACATGAATCCTGCCATTGTGGCTCCAGACGGCTTTGACATCATTGACATGACAGCGGGAGGGCAGGTTCATTCGGAGCAGAGGAGGAATTTGGCGTCCGTGGCTAAGATGCTTCAGCATGCAGCTGCAAACAAACTATTTGAGGACGAGAGCGACCACCTCACTCCCATGAACAGCTACATCTCCCAGACCTACCAGAAATTCAGG[T/C]GAGGAGAACAGAGCTTCTCATCAGTATCCGTCTTTACATCAAATGTAGAGAATTTTCTTTATGTGCAAATAAAGCATCGTTTCTATTCCAAGTGTTTAACAGAATAAAAGGGTCAGGCGGGTAATCCATGTTAGCCCTTTTTTCTTCCACAGGAATTTTTTATAGGTATACAGTTTATTCCTATTTCGAGGCTTTGTTTTTATGCAATAAAACATGGTATAGGAATAGGTTAATGGAAGGTAGGAGGGCATATTCCTGGATCAAGATCTATGTTTATCCTGGAACAACATTACACTCAGCCAATCAGGTTTAATTGAACAGTTTATGCTAATTTTAGGTTTACAATTAGGGTTATGTACTACCATCATTGTTATCTAACTATTATTCCCCTCTGATTTTGAGAATTTTTTTTTTTTTTTTTTTTAATTCAGTAATAAGTTGGACTTGGAAAATGCCAGTGGAAAGAATTTGTATAATTTGTGTGTCAGATGTTTTCATAA
Associated Phenotype:
Not determined