Busch Lab

ZMP

npas2

Ensembl ID:
ENSDARG00000016536
ZFIN ID:
ZDB-GENE-030408-3
Description:
neuronal PAS domain protein 2 [Source:RefSeq peptide;Acc:NP_840084]
Human Orthologue:
NPAS2
Human Description:
neuronal PAS domain protein 2 [Source:HGNC Symbol;Acc:7895]
Mouse Orthologue:
Npas2
Mouse Description:
neuronal PAS domain protein 2 Gene [Source:MGI Symbol;Acc:MGI:109232]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa38465 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa26455 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa33580 Nonsense Available for shipment Available now
sa20391 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa38465
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000014806 Essential Splice Site 197 845 6 21
Genomic Location (Zv9):
Chromosome 5 (position 24584412)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 22297284
GRCz11 5 22801084
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCACACATGCTTCTGACTGAGTCTTCTACTGTAGACCTGCTCAACAGCA[G/A]TGAGTAAACTGCGCATAAACACACACACATGCACAAACACACAGACACAC
Long Flanking Sequence:
TTTAAAAGACTTCTTTAATAATTACAAATTATAACATTAATAATAATAATAATAATAAAAATAATACTTAAAACTACTGATAATAGTAATAATATTAACCATTATGATGACATCTACAATATTAAAAAATTTATAATATATATTATATAATATAATATTATTTATAATATAATAATAACTATAATAATAATAAATAATAATTCATAATAATAATTATAATATTAAAATTTATCTACTAAGCAATTGTTATTTCATTTTTGTGATTGTGGTTATATATATATATATACTGTAAGTGCTATGTATTGTGGGAAATGTATTGCACAGTGTAGTCCTTCTGAAAGAGAGTAACTTTGTCATATACATTGCTGTGTCTTAGTCAGATATGGTGGACCAGAACATCCTGAACTTCCTGCCAGAGCGAGAGCACGCAGATGTGTATAAACTCCTGTCTTCACACATGCTTCTGACTGAGTCTTCTACTGTAGACCTGCTCAACAGCA[G/A]TGAGTAAACTGCGCATAAACACACACACATGCACAAACACACAGACACACACACACACACACACTAAAAAAGAATATGTCGTTGTATTTGTCGGCTGTGTTGTGCTCCATGATTACACTCCAGGCTAATTATAGAGGCTCCGTGTGTGCAGTGTAACACAGATTATCTGTTACCACACTCTAATAATCCCACATACAGCTCTTACCCTGACCTCAATCCCTGAAACACACACACACACTAATACTGGGATATACTGGTTGAAAAAAAATGGACAGAGCTGACTTATTGATCTCAGTCAATCACAACAAGCACCTACTTCACTGGTCAAACACAACCACATGCAAACACACAAACACAATATGTACACATAAGGACACACTTTCTGCTGCATGGCTCACTACTGCACTTCAGAATCATGAAAGTCACACTGAGGCCACAGCCATAGCAGACCATTAAAGCTGTAGTGTGTAAACTTTTTGGTATAAAATTATTCAAAACTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa26455
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000014806 Essential Splice Site 198 845 6 21
Genomic Location (Zv9):
Chromosome 5 (position 24584413)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 22297285
GRCz11 5 22801085
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCACACATGCTTCTGACTGAGTCTTCTACTGTAGACCTGCTCAACAGCAG[T/A]GAGTAAACTGCGCATAAACACACACACATGCACAAACACACAGACACACA
Long Flanking Sequence:
TTAAAAGACTTCTTTAATAATTACAAATTATAACATTAATAATAATAATAATAATAAAAATAATACTTAAAACTACTGATAATAGTAATAATATTAACCATTATGATGACATCTACAATATTAAAAAATTTATAATATATATTATATAATATAATATTATTTATAATATAATAATAACTATAATAATAATAAATAATAATTCATAATAATAATTATAATATTAAAATTTATCTACTAAGCAATTGTTATTTCATTTTTGTGATTGTGGTTATATATATATATATACTGTAAGTGCTATGTATTGTGGGAAATGTATTGCACAGTGTAGTCCTTCTGAAAGAGAGTAACTTTGTCATATACATTGCTGTGTCTTAGTCAGATATGGTGGACCAGAACATCCTGAACTTCCTGCCAGAGCGAGAGCACGCAGATGTGTATAAACTCCTGTCTTCACACATGCTTCTGACTGAGTCTTCTACTGTAGACCTGCTCAACAGCAG[T/A]GAGTAAACTGCGCATAAACACACACACATGCACAAACACACAGACACACACACACACACACACTAAAAAAGAATATGTCGTTGTATTTGTCGGCTGTGTTGTGCTCCATGATTACACTCCAGGCTAATTATAGAGGCTCCGTGTGTGCAGTGTAACACAGATTATCTGTTACCACACTCTAATAATCCCACATACAGCTCTTACCCTGACCTCAATCCCTGAAACACACACACACACTAATACTGGGATATACTGGTTGAAAAAAAATGGACAGAGCTGACTTATTGATCTCAGTCAATCACAACAAGCACCTACTTCACTGGTCAAACACAACCACATGCAAACACACAAACACAATATGTACACATAAGGACACACTTTCTGCTGCATGGCTCACTACTGCACTTCAGAATCATGAAAGTCACACTGAGGCCACAGCCATAGCAGACCATTAAAGCTGTAGTGTGTAAACTTTTTGGTATAAAATTATTCAAAACTCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33580
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000014806 Nonsense 241 845 8 21
Genomic Location (Zv9):
Chromosome 5 (position 24589131)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 22302003
GRCz11 5 22805803
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TAAACAGAATGTGTTGTTTTTGTGTGTGTTCCAGTGCCTCTGTCTTCATG[T/A]AATGGTTATGATCTGGCGTTTCCTCGCACGCTGCAGTCCTCAATAGAGGA
Long Flanking Sequence:
CACAAGAATATTGTTTAGTTGCAGCTGTTTTGCTGACAATGATTTAATAACCAAGACGAATTAAAGCACAATTAATAGTGAAATCATTAATCGTTGCATCCTATGTCCAACAGGGAAAACCGCCAACGATAAAGAATGCATGATCATATGGTGTCATGGCTTTAGTTTGCAAACAAAGTAATTATAATTGAAGTCAATTGGGCAAAAACAGGCATGAACATAACAAATGGTGGTAAATTTGCCCATAGCTTATTGTTGAGTTTCAAGTTCCAAAGCATTTTCCCAAAAATTGTGTCCAAATACAATTTGTCACCAAAAAATAATTTCATTTGCTGAAATACAGAGTAAGATGTGGCTAAATTAAGACTTAAAATCACCCCAAGTGGATGAAAACATCCCCAACATCACCCAAGGGTTAATATTTATCTGTCCACTGTGGGTGTTTTCCTTTAAACAGAATGTGTTGTTTTTGTGTGTGTTCCAGTGCCTCTGTCTTCATG[T/A]AATGGTTATGATCTGGCGTTTCCTCGCACGCTGCAGTCCTCAATAGAGGAGCAGGTCTGCCTCGTGGCCACAGTCAGACTCGCAACCCCTCAGTTCCTCAAGGTATACACACTCATTCACATACACACAAAATCAATATCACACACACTGCTCACTTTCACCATAACTTCAAAGAACACGCAGCCTTATTCTGTGTATGTGCATGTGTTTATTAAAGGATCTTTGCAACGTGGAGGATGTGTGTGATGAATTCACATCAAGACACAGTCTGGAATGGAAATTTCTCTTCTTAGATCACAGGTGAGTCAAATGCTGCTCCATTATGCAAACGACTCCTCTGCTGTTATGATTCTGCACGAAGCTCCTTTGGTTCATTCGATCAGAGGCTCTTCCTGATTATGTCATGCTTTTGATTCATTCATCAGCCGCTGACCCACTTACATTTGCACATTCAGGCTTTCCGCTGTCCCACGCATGGCTAGGGGTGTCATCAGTTCTGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20391
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000014806 Nonsense 349 845 11 21
Genomic Location (Zv9):
Chromosome 5 (position 24597503)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 22310375
GRCz11 5 22814175
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCGTTTGTGTGTATTGCAGTGATGCAGTGTGGGAAAGGAAAGTCTTGTTA[C/A]TATCGGTTCCTGACTAAAGGACAGCAGTGGATCTGGCTGCAGACGCACTA
Long Flanking Sequence:
TTTCTCAGCCCCTCTACTCTCAAAATTGTTCCATAACAATCTGCAGATTTTTTTTACAAATCAGAAATTCCACAGTTGCCCTACCGTTTTGTGCATGTTTTTAATGGGTACAGAGAGTATGTAATAACTGTGTGTGTGTGTGTGTTTACAGGGCCTCTCCTATCATCGGGTACCTGCCGTTTGAGGTTTTGGGGACCTCGGGTTATGATTACTACCATGTGGACGACCTGGAGCTGATTGCTCAATGTCATAAACAATGTGAGTGTTATCTCTGCTGCTCTCGCTCTCTCTTCGTTCTCAAACTAGGTCAATGTACTGTCTTGGAAATTTTCTCCTGTTTGTGCGAATCACAGAGGAGCTGAAAATGGCCCCGCCAGGAAAGATGAAAGACCTTGTAAGAAGCTCTCAAGCCTTTTGTAGAGAGTGCTGATCTTGTGTGTTTGTGTGCATGCGTTTGTGTGTATTGCAGTGATGCAGTGTGGGAAAGGAAAGTCTTGTTA[C/A]TATCGGTTCCTGACTAAAGGACAGCAGTGGATCTGGCTGCAGACGCACTATTACATCACGTACCACCAGTGGAACTCCAAACCTGAGTTCATCGTCTGCACACACAGCGTGGTCAGGTAAAACAAACACTAGCGGCATTTATATGTGTGTATGGAAAGTGTGGGCATGGCAAGCACACTGGAAAGTACTTGAACTTATTTATAAGCATATAAACAAAAACGCTTTGCTTCGCACAGTAATTTGAATTAGAGTTAATTTCATCTTTGCTTTAATATATATATATATATATATATATATATATATATATAAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGAAGAGATCAGATGCAAAGCCCTCTAAATCCATCAGACCTCTTTTCTTGTGAATAAGCATTTTCTATCAGGCTCATATAATAAGGTTCAGATGTTTCATTTCATAGATAATGAAAAGGTTATT
Associated Phenotype:
Not determined