ZMP
chek2
Ensembl ID:
ZFIN ID:
Description:
serine/threonine-protein kinase Chk2 [Source:RefSeq peptide;Acc:NP_956339]
Human Orthologue:
CHEK2
Human Description:
CHK2 checkpoint homolog (S. pombe) [Source:HGNC Symbol;Acc:16627]
Mouse Orthologue:
Chek2
Mouse Description:
CHK2 checkpoint homolog (S. pombe) Gene [Source:MGI Symbol;Acc:MGI:1355321]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa20350 | Nonsense | Available for shipment | Available now |
| sa33537 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa20350
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000036421 | Nonsense | 261 | 503 | 8 | 15 |
Genomic Location (Zv9):
Chromosome 5 (position 10977188)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 9564948 |
| GRCz11 | 5 | 10069586 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGTTTCTCTCTCCTCCTTTAGCCGTGCCTGATCAAAACTGAAGATTTCTA[C/A]CAGACTGAAGACTCCTACTACATTGTTTTGGAGTAGTAAGTAGTGTTTAA
Long Flanking Sequence:
GTTGATGTTTGCAGAATTTACTGGTCACGTGTGTCCATTATTAAAATTCTGCATTTGATAGTTTAGATCAGGGGTCAACAATCTCAGTCCTGGAGTGCTGGTGTCCCTGCGGGGTTTAGCTCCAACTTGCCTCAACACACCTGCCTGGATGTTTCAAGTATACCTTGTAAGACCTTGATTAGCTTGTTCAGGTGTGTTTGATTAGAGTTGGAGGTAAAATCTGCAGGGCGCCGGCCCTCCAGGAACAAGTTTGGTGACCCCTGGTTTAGATTTTGCTCGCACACGCTGATGTTTATCGTTTTTTGGTATTAAAATGTTTTATTTGCGTTTTACAGACAGCCACACGAAATGCTGAGCGGGAAATCGAAATTTTAAAGAAAATTGATCATGTAAGTCAAGGATTACATTTTAAATTGACAGAAATAAGGATTATTAAATACGTTTGTTCGTGGTTTCTCTCTCCTCCTTTAGCCGTGCCTGATCAAAACTGAAGATTTCTA[C/A]CAGACTGAAGACTCCTACTACATTGTTTTGGAGTAGTAAGTAGTGTTTAATTGGGGTTAAATTACGAATTTCCTCTTGTAAATAGTTTTTAAGGATACTTTTAAAGGCAATTTCATGTAAGGTAGTACTAGAAGTTCGTAAAACGCTGCATAATTTGAACGTTCAATCGATAGTTTATTGAAAAATGAAAATTTACTGCTGTTTTACTCACCCTTAAGCTACTGTATGAGAAGTAAATGATATTTTCGTCTTCAGAATAACATTATTAATTGTAAACAGAATAACAGTACGACTTTTAGCTCAACCTGAGTTTCTTGGTGATTCATAGAATGCAAGTCAAGTACTTTTAGAGTAAAAGAAATAAAGTAAAATGTTATACCCTTTGCCTCTGGTGATAAATTAAGGTCTTGCGAAGTGAAACCATTGGTCTACGAAAAAAAAAGAAGAAGCATTTTAATGAGCTTTTTAGGCTGTTCAAGTCAAAGGTAAAAGACATCTGA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa33537
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000036421 | Nonsense | 295 | 503 | 9 | 15 |
Genomic Location (Zv9):
Chromosome 5 (position 10971769)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 9559529 |
| GRCz11 | 5 | 10064167 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCTGTTTGGCAGGATCAAGGCCAAAAAAAAACTGGAGGAAGATATCGCC[A/T]AACTCTACTTTTATCAGATGCTCAAGGCTGTGGAGGTACGACTTTATGAA
Long Flanking Sequence:
TGGCCAATTTAAAGGCTAAGGGTGTGTGCCTAGGCCTAGTTAGAGTGCTGAGATGTTACGATGTTACAGAGGATTTATTTTATTTCTTTGCTACAACTTCTAAGTGGCATATAGCCAAAGTTTGTTACGAATAAATTATGTTAAAAGGCAAAAGATCTGTGTGTAGGTGCACATTTGAATAATGTCGGGCTATATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCTTTTTTTAATGAGATCAACTTTAAATCTATGCAGCAAAGCATTTAAGATTGGCAATCATTTAAGTTGAACATGTCATTTTATGTCTATGTTCAGAAAGTGGGGGTGACCGTTAAGGGGTCAATACCTTAAATGTTGTCAAATTAATGCATTAAGCAACCATTTCAGTAATTGAATAAATGGTGTATTCTCTGTGCTGTGTGTAGTATTGAAGGTGGCGAGCTGTTTGGCAGGATCAAGGCCAAAAAAAAACTGGAGGAAGATATCGCC[A/T]AACTCTACTTTTATCAGATGCTCAAGGCTGTGGAGGTACGACTTTATGAACAACATCTTATGTGTTTTAAATTAAAGGCTGATTTATACTTCTGCGTCAAACGCCGGCGTATGCTACAGCGCTGACGCATAGCCCTTCGCCGTGGCCGTCGGCGTCGCTGACGTGCACCTCTCCAAAAATATAACTACACGTCGCAAAGACGCGTAGCGCAAGCTCTGTGATTGGTCGGCTTGTTAGCTCTGACAAGTCTGAGCGGGACCGAGAGCCGCGCGAATGGTGCGAGCCTGATGGAGCGATTGTTTACAAGTGTGGAGTCCCGTGAAGGAGCTCCGGATGGAAAGTTTTGTTTTGTGTTTACCTCATAGTTAAAGCTGTTGCATGTCCGCCGGTTCCTGCCTCAAAATGAGCGAGTTTGAGCCACTTGTACATCCAGGAAGTGTTCAAGAAAAGCAAAACAGCAGAGAAGAAACTCGACACAGAGGAACATTTACACCTCACTG
Associated Phenotype:
Not determined