ZMP

si:ch211-283g2.3

Ensembl ID:

ENSDARG00000046092

ZFIN ID:

ZDB-GENE-060526-152

Description:

Novel protein similar to vertebrate asialoglycoprotein receptor 2 (ASGR2) [Source:UniProtKB/TrEMBL;A

Human Orthologues:

CLEC4A, CLEC4C, CLEC4D, CLEC4E, CLEC6A

Human Descriptions:

C-type lectin domain family 4, member A [Source:HGNC Symbol;Acc:13257]
C-type lectin domain family 4, member C [Source:HGNC Symbol;Acc:13258]
C-type lectin domain family 4, member D [Source:HGNC Symbol;Acc:14554]
C-type lectin domain family 4, member E [Source:HGNC Symbol;Acc:14555]
C-type lectin domain family 6, member A [Source:HGNC Symbol;Acc:14556]

Mouse Orthologues:

Clec4a1, Clec4a2, Clec4a3, Clec4a4, Clec4b1, Clec4b2, Clec4d, Clec4e, Clec4n

Mouse Descriptions:

C-type lectin domain family 4, member a1 Gene [Source:MGI Symbol;Acc:MGI:3036291]
C-type lectin domain family 4, member a2 Gene [Source:MGI Symbol;Acc:MGI:1349412]
C-type lectin domain family 4, member a3 Gene [Source:MGI Symbol;Acc:MGI:1920399]
C-type lectin domain family 4, member a4 Gene [Source:MGI Symbol;Acc:MGI:3624119]
C-type lectin domain family 4, member b1 Gene [Source:MGI Symbol;Acc:MGI:1917060]
C-type lectin domain family 4, member b2 Gene [Source:MGI Symbol;Acc:MGI:3588267]
C-type lectin domain family 4, member d Gene [Source:MGI Symbol;Acc:MGI:1298389]
C-type lectin domain family 4, member e Gene [Source:MGI Symbol;Acc:MGI:1861232]
C-type lectin domain family 4, member n Gene [Source:MGI Symbol;Acc:MGI:1861231]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa6959	Essential Splice Site, Missense	Mutation detected in F1 DNA	Not yet available
sa33522	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa6959

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Essential Splice Site, Missense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000100085	Missense	44	131	1	3
ENSDART00000145912	Essential Splice Site	195	280	None	7

Genomic Location (Zv9):

Chromosome 5 (position 4244393)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	5	3904062
GRCz11	5	4237097

KASP Assay ID:

554-5024.1 (used for ordering genotyping assays)

KASP Sequence:

GAAAGGCGCATGGCTCTTAAAAATTGAAGATGACTCTGAGGATGAGTGGG[T/A]GCGTAATGAATGTACATAGACACATGGTTTTCCTTATCACAGGGCTCTAG

Long Flanking Sequence:

TCAAGAACGCATGATTATATGCTCTTATGGCTTTGCAATCAATAAATGTGATTATAAATGGAAGTCAGTGGGGCAAAAACAGCCACCAACATAACCAAAGGGTAGTACTCAGTGTATTGTTGACTTTTTAAAAAAAATTCCAAAGCATTTTCCCAAATTATGTGTCAAAACAAGATTTGTCAGCAAAGATCATCCCATTTGCTGAGACTCAAAATCACATCAGCTTGGATGAAAACATCCCCAACAGCACATGAGGGTTAATTCGATTTTTTTTCATCTGACATAAATGCATTGAACAAAAGCATAAAAACATTCTGCATTCTTTCTCTCCTATGCAGAAGAACTTGAATCAGGCTGCAGTGATTCTGCTTGGGTTCCTTTCGGCAACAGCTGTTACCTCTTCTCTCGTGATAAAATGAACTGGACAGAAGCAAAAGATTACTGCGAAGAGAAAGGCGCATGGCTCTTAAAAATTGAAGATGACTCTGAGGATGAGTGGG[T/A]GCGTAATGAATGTACATAGACACATGGTTTTCCTTATCACAGGGCTCTAGATTAGAACTGCCCAACATCCAGCAAGATAGATGTTTAAAAATGTTGAGATTATTGACATAAACACAAAAGATTATTGCCACTCACCCGTATAGAGGTGCTGACAAAAAAACACAATAGAAGTCAGACTGACAGCCAGTTCTGTACAACAGGCAATTGTGTTATATTCAAATTCATTCATATATGTTGCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATACAGTTCTCATCATAATTGAGTACAGCCCATTTTGAAAATAAATATCTGTATCTATTTCTCAGTGAATATAGGTAATGCATTTTGGTGCATTTAAACATTCATTCATTCATTTTCTTTTCGGCTTAGTCCCCCATTATTAATTAGGGGTCGCCACAGCGGAATGAACCGTCAACTTATCCAGCATATGTTTTACGCAGCGGATGCCCTTCCAGCTGCAACCC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa33522

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > T

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000100085	Essential Splice Site	47	131	2	3
ENSDART00000145912	Essential Splice Site	196	280	6	7

Genomic Location (Zv9):

Chromosome 5 (position 4243170)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	5	3902839
GRCz11	5	4235874

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

ACAGTATGTGCCCATTCTGTCTTTAAGTGAGCCTTTGGTCTCTTTTACTA[G/T]CAATTTGTAACTGATTTTGCCAATCCAACTCATTACTGGATCGGCTTAAC

Long Flanking Sequence:

CTTTACCACGGGGAGCTCCCATCTGATCTCGTACTCCCCTTACATGCTCAATTGACTAGGCGGGAGCCCGGGCTCAATTATTTCCGAACTCAGGGCTCTCTCCCGAGACAGCATGCCAACATGGCTAATAGCGTCATGCAATATCTAAGTGTAAACTCTTGAAGGACAATTTAGCCTACCCGATTACCTAACTAAAACTTTCAATTCTTTGTTTCTCTTGATTTTTCCTCTTTTTAAATTTTTTTATTTAATATTTTTCTATAACAAATCAATTTGGCTGTGCTAGTTTTTGAATCGTTATTGTGAGTTATTTTGTTAGACAAGCTCCATTTGGCTTTAGTACTGACTAATCTAATGTATATGTACAAATATACTATTGTACAGCTTCCTATTAAAAATATGAATTTAAAAGAGTTTCGTATGGGGTGTACTTATATGAGCACTGTATATACAGTATGTGCCCATTCTGTCTTTAAGTGAGCCTTTGGTCTCTTTTACTA[G/T]CAATTTGTAACTGATTTTGCCAATCCAACTCATTACTGGATCGGCTTAACGGATCAGAACACAGGCCAGTGGAGATGGGCAGATGGAACTAATTACACCATGAACAAAGAGTGAGATGAACACACAAATATACAGAACACTTTTTACTAAGTCTGATTTAAGAGAATTCACATTTATAACCAGACATATTTTATTGTTGCAGACACTGGGGACCTGGACAGCCGGATGAGTGGACTGAGCATAGCTTGGGAGAGGAAGGAGAGGACTGTGCGGAAATTACATATGAATCTCTGCTCAATGACCTGCACTGCTCCTCCAAAATAAAGTTCATTTGTGAAATGAAAACATAGGACTGAGAATGGAAACACTTGAGTGTGGTCAAAACTCTAAATATGGAATTTTAAATAAACAACTTTTGAGTATTGAGAATTTGTAAAAGGACATTTTGTTAAAATTGTTATATTGGTTTAAGCTTGTAAATTTAAATGAATCATTTATCA

Associated Phenotype:

Not determined