Busch Lab

ZMP

fgd6

Ensembl ID:
ENSDARG00000045528
ZFIN ID:
ZDB-GENE-041210-200
Description:
FYVE, RhoGEF and PH domain-containing protein 6 [Source:RefSeq peptide;Acc:NP_001093450]
Human Orthologue:
FGD6
Human Description:
FYVE, RhoGEF and PH domain containing 6 [Source:HGNC Symbol;Acc:21740]
Mouse Orthologue:
Fgd6
Mouse Description:
FYVE, RhoGEF and PH domain containing 6 Gene [Source:MGI Symbol;Acc:MGI:1261419]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa33478 Nonsense Mutation detected in F1 DNA Not yet available
sa45178 Nonsense Mutation detected in F1 DNA Not yet available
sa33477 Nonsense Mutation detected in F1 DNA Not yet available
sa33476 Nonsense Mutation detected in F1 DNA Not yet available
sa40307 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa33478
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000066949 Nonsense 942 1315 9 21
Genomic Location (Zv9):
Chromosome 4 (position 24966015)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 25889684
GRCz11 4 25878882
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TAGATTATTTAAAAAATCTTCCTGAGGATTCTTCCGACTACAAAGACACA[C/T]AAAGTAAGAGCACATCATTAATAAAATAACCAGAGACCAGTGAAAAAAAT
Long Flanking Sequence:
TAGCCCTGATTAACTCAATCAGGAACTAATGAGGTGAAAGAGTAAAATAAATTTAGGGTTTACATTTCTAGAATTTATCTGTAGAGCCCTGGATAGAATCTAGAGAGAGGAAACCATAAGATGTGTTAACCAAATGTTGGAAAGGTGAGGAGTTGCAATGAAGCAAAATGCTTTTTAAATAGAACTCTGATGTCATATTGGCTTGGGTGCACACCAAAAGAGCTAGTGTGAAGTCACCCTTAGAGAAATGAAGCAAACCTGCATTATATATCATGAGAAAATAAAAACACATAATATATAATGTTCATATAATTCTATTACATTATAACATATAATTCTATGTTATAATGTAATAGAAGACCTCCTAAGCAAAATAGAAACCTTTAAAATAGCATAATGAATGTCATTTTAATAAAACTAATATCTTTGACCTTTTTTTGTCTCTTTTTTTAGATTATTTAAAAAATCTTCCTGAGGATTCTTCCGACTACAAAGACACA[C/T]AAAGTAAGAGCACATCATTAATAAAATAACCAGAGACCAGTGAAAAAAATCTAATAAAATGGCCTGGTTTTATACAGAGTAACACAAATTCAGAGTGAATGTTTATCAGTCTGACTGTTAATTATTTACTAAAACATAGTTTAAGTATGTTTAGATCAAGAACCATTTGGTGAGATTAAAAAAAAAACTTTACTTAAAGGGCACCTATGATTAAAACATGTTTTGTAAGCTATTTGAACAGAACTGTGTGTAGGTATAATGTGTCCACAGTCATATTGGGGTGATCGAAACACAATAAGCATGTATTGCATAGGAATGTGGTTTCCCTGCCTACCGATTTGATTGGCAGTCACGTATAAACATGTCTCTGTAGTAACGCGTATAATCATATTAACAAGACAGGACGTGCGCAAAGCAACAGGGATTAAAAGATCTTTTCAGCTTGTTGTGATCATCAATCAGCATCAAATGTGATCAACAATGAGTTTTAATAGTTTTAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa45178
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000066949 Nonsense 1094 1315 15 21
Genomic Location (Zv9):
Chromosome 4 (position 24963095)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 25886764
GRCz11 4 25875962
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTACAGCAATAGATGATTACACCAGAAAGAAGATTTCGTTCTTCTCCAGT[C/T]GAAGCCAAGAGGTGTGTGAAATTTAAGATGCGTTCTTGTGTTTGTGTGTA
Long Flanking Sequence:
CTGAATAAGCTAGCACTTGTTTTTTGATACCCAGTCAATGTTCATTCTCTCAACAGTTTAATGACATCCTGCTGTACACAACACCAGTGCAGTCTGGACAGTATAAAGTCAACAGTATGCTCTCTCTGGCTGGCATGAAGGTCAGATATCAATTATCCATAATATGTCCACTCTCTCAAACACGCATTCATATGACATTTTATATATAAGTGTTTATGTTCCATGTCTTCAACAGGTGAGCAAACCCAGTCAGGAGGCGTATCAGAATGAGTTAAACATTGAGAGTGTTGAAAGATCCTTCATACTGTCTGCCAAGTAAGAAACACACACAAGCATGTGATTTTCAGCTATGTCAAAACTGGAAATCATTTTGAATCGAGTTGAAATGACTGACTAAACGTGATGTTTGCAGTTCAGCGACTGAAAGAGATGAATGGTTGGAAGCCATTGCTACAGCAATAGATGATTACACCAGAAAGAAGATTTCGTTCTTCTCCAGT[C/T]GAAGCCAAGAGGTGTGTGAAATTTAAGATGCGTTCTTGTGTTTGTGTGTAGGGTTATTGTTCTTGTGCGTATGCCATTCCGTCAACTGGCAATATTTGCTTTCTTTAATTGATTTCCACAGCCATTTTTTTAAACGACAATTTTCTTTTGTTTTATTTACATCAAGTACTTGAATTTAACTAGTTAAAAACATTCAGAATACTATGAACTGTTATAAGTAATAATAAACAGTTTTATCGTGTTTATCTGAGATGCAAAATGGCATAAGATACAAGTCTTGTTAGTCTGTCAATATCTGTATCTGCTAAAAGGTGGATACAAAGGCTTTCATTTATTATTTTAATTTATAATATTAATTTATCAATTAATATTAATCACATATTTTTGGAAGTCATTACTTTATAATAGCCAGTTTAATGCTTTAAAATTCAGTGAAATAATACAACACAAAAAAAAAAAATTATATTGGAATTAATAGTTTTTTTTTTCAAACAATTAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33477
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000066949 Nonsense 1151 1315 17 21
Genomic Location (Zv9):
Chromosome 4 (position 24959781)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 25883450
GRCz11 4 25872648
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCATGATAAGAGATTTGTTTACTTTGGCCACAGGTGGTGTGTCAGGCATG[T/A]TCGTCTAATAAATTCTACCTGGAATACCTGAAGAATCAACTGGCAAGAGT
Long Flanking Sequence:
TTAAGGTCAAAATTATTAGCCTCTTTAAGCTATAGTCTATAGTCTACAGAACAAACCATCATTATACAATAACTTGCCTAATTACCCTAACCTGCCTAATTAACCCAGTTAAGCCTTTAAATGTCACTTTAAGCTGTATAGAAGTGTCTTGAAACATATAAATCAGTTATTAGAAATGAGTTATTAAAACTATTATGTTTAGAAATACGTTTTCTGTTAAACAGAAATTCTGGATAAAAATAAAGGGGGGCTAATAATTCAGATTTCAACTGTAGATGTTTTTATATTTGTATACTCTGATGCTATTTAATGCTCAATCTTCTTTTTGTTAATTGTGTTGATTGTTATATTGTAAAACGATAAATCATAATTAATAATAATAAAAATGAATTTACAGAAATTGTTCTATGTTGATGTACATATCATAATCAGGGCTTGAGATTATTTACATCATGATAAGAGATTTGTTTACTTTGGCCACAGGTGGTGTGTCAGGCATG[T/A]TCGTCTAATAAATTCTACCTGGAATACCTGAAGAATCAACTGGCAAGAGTGTGTGACCATTGCTATATTAAACTACAGCACAAGGGTATGTGATTTCTGTTGTTTATCTATCTCTGGACTGTTCCATGGCTCCATCATCTATAGTAGTAATAGTGTTTATTGTTCTATTTTTAATGTGGTTATGCTTAGTGTTCAGTTCTTATGCTTAAACGGTCCTTTCACCCCAAAATAAAAATTGTCCTTATTTACTTGTTCATCTTCAGAACACAAATGAAGATACTTTTTTCCCCTAAAACATAATTTATTGGATTTTTTTTTCCGAACAAAGTATTGACCTTATTCTTCAATGCGGAAGTGCGCTCGTTTTTGCGTTGTTTTAGAACTTTTGATTCAGTTGCCAGGTAGAAATAGCTAAAACGGTCAAACTACTTGCTCTTCCAACAAGTGTGTGCATGACTATACAGACAAAGCAGAATAATATAATAGGAAAATATCAGTGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33476
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000066949 Nonsense 1200 1315 18 21
Genomic Location (Zv9):
Chromosome 4 (position 24955462)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 25879131
GRCz11 4 25868329
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCAATGTGACCTTTTCCCCTAGTGGGCGGGGCTCAACATTCGCTTTTTCT[A/T]GAAAACAGAAGAAGATTCCATCAGCTCTCAAGGAGGTAATCTAAAGTTAA
Long Flanking Sequence:
CGTTTCCATCTTCTTTCTGGCCTTAAATGAAAAGCAAAAAAGAACTTCATTTGAAGTATGCCTTTAGTAGCTGAGACTGAGCATTTATATACAGCTACTCAGCTACTGGAATCTGGCTTAAATGCGCAGTAGCAGTGTGTGGATGCTGATGTTGAGGATGATTTGCAGTGCTTCTTTTATACTCACTTGTAGGTCACTTTGGATAAAAGAATTTGCTAACTGAATAAATGTAAAATGTAAATAATCAAACCCCAGATAAAACACTAAATCGGAATGTGACCCAGAGGACTCTGAAAACTCTTTTGACAGGTGAAAACCTGGCAATCGCACAATATGCTATTGCAACCGCATATTATTATTTACTTACAACAATCTGGCAAACAAGTTGTGTGACAGCAAATGTTTTTTTTATTTTTCAACCATGCTTTTTTTGTTTCTTAGGCGACCAATCCAATGTGACCTTTTCCCCTAGTGGGCGGGGCTCAACATTCGCTTTTTCT[A/T]GAAAACAGAAGAAGATTCCATCAGCTCTCAAGGAGGTAATCTAAAGTTAAACAATACTTAAAGGGATAGTTCACCCAAATGTCACTAAACATTACACTTGCTCAATAACTTGATTCAACTCTAAGTTGAATACAAAGAATTTCTTTTGAAGAATGCTGGTTGATGGTACCCATCATGATGACTTTTTTCCAGTGGGTACTATCTAACAGCAATTCTCTAAAGATCTTCTCTTGCGTTTAACAGAATAAAAACTGCTGTTTCCAAAATAACACTAATGTCATTTTTATAGTTTATTAATATGACATCGTTCTCACAGGTGTCTGCCAACACTGAGAACTCCTCCATGAGTGGATATCTGCACAGATCTAAAGGCCACAAGAAACCATGGAAGAGGCTGTGGTTTGTCATTAAGAACAAAGTCCTCTACACTTATGCTGCCAGTGAAGTAAGCTGAATTTATTCAACAACTTATCAACTGTTAAAGAAACAAGCTTTATATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40307
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000066949 Essential Splice Site 1211 1315 18 21
Genomic Location (Zv9):
Chromosome 4 (position 24955426)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 25879095
GRCz11 4 25868293
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATTCGCTTTTTCTAGAAAACAGAAGAAGATTCCATCAGCTCTCAAGGAG[G/A]TAATCTAAAGTTAAACAATACTTAAAGGGATAGTTCACCCAAATGTCACT
Long Flanking Sequence:
AAAAAGAACTTCATTTGAAGTATGCCTTTAGTAGCTGAGACTGAGCATTTATATACAGCTACTCAGCTACTGGAATCTGGCTTAAATGCGCAGTAGCAGTGTGTGGATGCTGATGTTGAGGATGATTTGCAGTGCTTCTTTTATACTCACTTGTAGGTCACTTTGGATAAAAGAATTTGCTAACTGAATAAATGTAAAATGTAAATAATCAAACCCCAGATAAAACACTAAATCGGAATGTGACCCAGAGGACTCTGAAAACTCTTTTGACAGGTGAAAACCTGGCAATCGCACAATATGCTATTGCAACCGCATATTATTATTTACTTACAACAATCTGGCAAACAAGTTGTGTGACAGCAAATGTTTTTTTTATTTTTCAACCATGCTTTTTTTGTTTCTTAGGCGACCAATCCAATGTGACCTTTTCCCCTAGTGGGCGGGGCTCAACATTCGCTTTTTCTAGAAAACAGAAGAAGATTCCATCAGCTCTCAAGGAG[G/A]TAATCTAAAGTTAAACAATACTTAAAGGGATAGTTCACCCAAATGTCACTAAACATTACACTTGCTCAATAACTTGATTCAACTCTAAGTTGAATACAAAGAATTTCTTTTGAAGAATGCTGGTTGATGGTACCCATCATGATGACTTTTTTCCAGTGGGTACTATCTAACAGCAATTCTCTAAAGATCTTCTCTTGCGTTTAACAGAATAAAAACTGCTGTTTCCAAAATAACACTAATGTCATTTTTATAGTTTATTAATATGACATCGTTCTCACAGGTGTCTGCCAACACTGAGAACTCCTCCATGAGTGGATATCTGCACAGATCTAAAGGCCACAAGAAACCATGGAAGAGGCTGTGGTTTGTCATTAAGAACAAAGTCCTCTACACTTATGCTGCCAGTGAAGTAAGCTGAATTTATTCAACAACTTATCAACTGTTAAAGAAACAAGCTTTATATAATTTATCAGTGTTAGCTCATAATATGAATGTTGACA
Associated Phenotype:
Not determined