ZMP
impdh1b
Ensembl ID:
ZFIN ID:
Description:
inosine monophosphate dehydrogenase 1 [Source:RefSeq peptide;Acc:NP_001014391]
Human Orthologue:
IMPDH1
Human Description:
IMP (inosine 5'-monophosphate) dehydrogenase 1 [Source:HGNC Symbol;Acc:6052]
Mouse Orthologue:
Impdh1
Mouse Description:
inosine 5'-phosphate dehydrogenase 1 Gene [Source:MGI Symbol;Acc:MGI:96567]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa33452 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa33453 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa33452
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000045866 | Essential Splice Site | 228 | 537 | 7 | 15 |
| ENSDART00000066973 | Essential Splice Site | 232 | 539 | 8 | 16 |
| ENSDART00000066975 | Essential Splice Site | 207 | 514 | 7 | 15 |
| ENSDART00000139730 | None | None | 126 | None | 4 |
Genomic Location (Zv9):
Chromosome 4 (position 18046062)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 18988902 |
| GRCz11 | 4 | 18977878 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGTGTCACATTAAAAGAAGCCAATGACATCCTGCAACGCAGCAAAAAAGG[T/G]AACAACAAACAGATTGTGAAATTATATCATCGTAGCCATTAACTGAATAT
Long Flanking Sequence:
TATGAAATGTTTCTGTTACAAAGACACATCAATGTGGTTCATAAGATACGTTAACCCTTTGGCAACGTGGGTTTGATGAACGATTTATGCGCTTTTGGGTGCTTTAAAATAAGCCACTATCCTCCACCCCATTATATAGCATGGAAGAGCCAGGATAAAATATCAAATGACTCAGACTGTGTTCGTCTGACAGAATAAAATGTCGAAAATGGCACAAGGGAGTAAGTAAATTAAATCATTTTCACTTTTGGGAAAACTGTTTCTTAAAGAAAAGCTTTTCAAAGTATTTTTCACAGAGTATTTAATTATGTTGGTTAACATTATATTTACAAACAGAACTGTATTGTAAAGTGTTACCATAAAACATCAGTGCTGGGCTCTTAAGACGGTGTGTCTGTTATTGACTTCCAGGCCATGACTAAAAGGGAAGATCTTGTAGTCGCTCCTGCCGGTGTCACATTAAAAGAAGCCAATGACATCCTGCAACGCAGCAAAAAAGG[T/G]AACAACAAACAGATTGTGAAATTATATCATCGTAGCCATTAACTGAATATCAGTTGTCCTTTGAGTCCTTCAGTTCCCTTCCACCCATATTAAACTTGCATCTCCAGTTTCACAAACAAGGCTTAAGGAAAATCCTAGACTAAAATGCATGTTTGAGCTATCTTAAATGAAAATAACTTGCATTGATATATTTTAAGATAAGTCAGTGTGAATGTTTAGTCTCAACATACACACTAGTGATATGTTTTTCAAAGGCATTTTAATATGAGCTGCTTCAATACATGATTAAATTAAGGCCTAGGCATGGTTTACGCAAAGCCTTAATTGTGAAACTGACATCCTGTATTAAAGGTTTTGATAGTGTTATGTTTATATATATGAATGAGCCATTTTTTATTAAATGAGAGCAATTTTGCATATATTTCTAGCACAAACAAATGAACACTAGATGTAGTCATGTTAAAATACTGACAATGAGAGATGTGACGATGATAACTGAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa33453
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000045866 | Nonsense | 416 | 537 | 12 | 15 |
| ENSDART00000066973 | Nonsense | 420 | 539 | 13 | 16 |
| ENSDART00000066975 | Nonsense | 395 | 514 | 12 | 15 |
| ENSDART00000139730 | None | None | 126 | None | 4 |
Genomic Location (Zv9):
Chromosome 4 (position 18050049)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 18992889 |
| GRCz11 | 4 | 18981865 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTGTTTTTTGTGCGCAGTGATGATGGGGTCTTTGCTGGCCGCCACCACC[G/T]AAGCTCCGGGAGAGTATTTCTTCTCTGATGGGGTGAGACTGAAGAAATAC
Long Flanking Sequence:
ATGACAGAATCTTCATTGAATTAATAAGAAACAATCCCAACGCTCTTTTTTTTATCCTATTATTTCAAGTTATATCAGAGTTTTTTGTGCAGTTTTGATAGCACATGACGTCTTGCAACTGCTATTGATTTTAACTGTCTAAAATAACATGGTTGACCATTCCAAGATGGCGAATGTGTCTAGAGCAGTCAAATGTGTATATCTGTGATCATTATGGCTGACATGTTTCATTTTGGCTTCTTCTAGTCATGGCTTGTGGGAGACCTCAAGGTACCTCAGTTTATAAGGTGGCAGAATATGCTCGGCGGTTTGGAGTGCCAGTCATTGCAGATGGAGGCATCCAGACTGTCGGCCACGTGGTGAAGGCTTTGTCTCTGGGGGCATCGACAGGTAATTATTACACTAGCTCACTGTTAGCATTGAAATGGGCTGAAAATCTGATTACATACTTGTGTTTTTTGTGCGCAGTGATGATGGGGTCTTTGCTGGCCGCCACCACC[G/T]AAGCTCCGGGAGAGTATTTCTTCTCTGATGGGGTGAGACTGAAGAAATACAGAGGCATGGGCTCACTGGATGCCATGGAAAAGAACACCAGCAGCCAGAAACGATACTTCAGGTGCGTGTTTGTTGAGATATTCAGCATTAGGAAAACTACTGATATGGTTAGAATTAAATACTGTGCCAAATAAAGGCCTTAAAGTAGCTTAATGTAGTATAAACTAATTGTTTTTTTAGATTACACTTTACGATACGCGTAAAAATGTTCTCTTACTTGGAGTTTTTGTCTTGTTTTTTTGTCCAAATATCTAAAAGTTCTCAAATCAAGAAGCTTTTTTTGGACATTTAAAACATACATACTTGTTTTAATAAATAATTTACCAAAATTAAGTGGGGTTTTCTTAAAATCAAGCTAAATAATTGGTCAATGGGGTAAGTTAAATAATCTTGTTTTTTCTTTTGACATCGATTATTTTGCTTGCGCCGCTGGCAGATTATTTAGCTAG
Associated Phenotype:
Not determined