Busch Lab

ZMP

A5WUP3_DANRE

Ensembl ID:
ENSDARG00000039392
Description:
Novel protein [Source:UniProtKB/TrEMBL;Acc:A5WUP2]
Human Orthologue:
WNK1
Human Description:
WNK lysine deficient protein kinase 1 [Source:HGNC Symbol;Acc:14540]
Mouse Orthologue:
Wnk1
Mouse Description:
WNK lysine deficient protein kinase 1 Gene [Source:MGI Symbol;Acc:MGI:2442092]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa12971 Nonsense Available for shipment Available now
sa20204 Nonsense Available for shipment Available now
sa17370 Nonsense Available for shipment Available now
sa33383 Nonsense Mutation detected in F1 DNA Not yet available
sa33382 Nonsense Mutation detected in F1 DNA Not yet available
sa45163 Essential Splice Site, Missense Mutation detected in F1 DNA Not yet available
sa16047 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa12971
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
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Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000012928 Nonsense 450 1909 5 27
ENSDART00000132228 None None 202 None 3
ENSDART00000134887 None None 1089 None 15
ENSDART00000146622 None None 201 None 4

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 4 (position 7275572)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 8086791
GRCz11 4 8095420
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AACCTGGCAGTTTCGACAAGGTAGCCATTCCAGAAGTKAAAGAGATCATC[G/T]AGGGATGTATTCGGCAAAACAAAGATGAAAGGTAACTACTGTWCACACAC
Long Flanking Sequence:
ATATGCTTTTAATTGTTTAAAAATAAACTTAACTGAATGCTATTAAAGTGATGTTTACACCATATCTGCATTTTAATATCGCAGCAACAGCTGGAGGTCTGTAGTCCACAGCATGTTACAATGTTTGCTGATCCTGTACTTCTGCATCCTCGCTTTTAAAACGGTGGCCACATGAAATAAGCGTATGGCAGACATCGATATTGCTATATTTGTAGTTGGAGATTTGAATAAACTCTACCCTAAGTATTAAAACTTCTCTCATCTTCTCCCGTTTGTATGAAATATATAATATTTAAAAGTGTGTGGGCTGTTGAGGAACTGATTTTTCACCTAGAAGACATTTAGTATGTAGCGTCATTGAGTCCCCGTGGAGCTCCAGTGAGATTTCTTTCACAGCACGGAAGACATGTTGATTTAATGCTCTTTTGTGCTTTACTCCACAGGGAGTTAAACCTGGCAGTTTCGACAAGGTAGCCATTCCAGAAGTGAAAGAGATCATC[G/T]AGGGATGTATTCGGCAAAACAAAGATGAAAGGTAACTACTGTACACACACCCACGCCACATTCATAGAACCCATTCATCTAGTCATACCTCACTTCTCCACGACATGTGCCGTGTGCCTGCCTGCAGATGAGGTGAATCCGTGCTGATGTGTGGGTATATCGCGGACTTGCGGTCCTTGTATGTGGAATATACACAGTAGCAAGAGATAAGAGGATTCCTACATGCTTGTTTTGATAAAGTTCCAACAACAAGGCTCTTAGTGAAGCAGATCTGTGAACACACCAAGCCAAGAGTGAAGAGTGTGATGCATCCTCAAGCTTTTACCATACTGTCTCTAGTTAAACATCAAGTATTTATATCCATATCGTATTTTAGCTTAAATGTAACTGATATCCATTTAAAGTGATGAAACCGATGGTGAAATTTGGTGTGTTGAGCGTAACGTGATGCAACGACTGATGCTCTGCTGAAGAAGCTGTGGAAAAGCTGATGTTTTGTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20204
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000012928 Nonsense 674 1909 8 27
ENSDART00000132228 None None 202 None 3
ENSDART00000134887 None None 1089 None 15
ENSDART00000146622 None None 201 None 4

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 4 (position 7272261)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 8083480
GRCz11 4 8092109
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCAGCCAGCTAAGCATGTCGTATAGTTCTCCTGGAACATCCCAACAACAG[C/T]AGGTCCCAGGACAGGGCACCTACACTCCCAGCTCTCAAGCTCCCCAACAG
Long Flanking Sequence:
TATTATACAAATACAGAATTCTCAATTTGTTTATAAATAAATATATGTTTTGCATTTTTATATTTGGTAGATCATTCTGTCTTGGTCATTTTATAAGTACTGTAGCTTGCATGCTGAAAAAGTGTGGGCACCCCTGATGTAAACATTGTACTCTTTAGATTGCAGCTTTGTTTCTGTCTGCATCCCGTAATGACATGTAATTTCGCACTCATATACATTATGAAAAAGTATTACCGTAAACAATGAAGTTTGTGACACCACAAAATAAAATAGAGCATAATATAAAATGATAGACTTTTTATTTTGTCCATACGATGTATACTGTATCACACAACCATAGATCTGGCTATTGTTTCCTTTATATATATCTGTGAATGTCATTTCTTTGCCCAGTGGCGGACGGGACATTTGACAGTGGTCAGGGTTCATCAGTGTTCTCAGAACCTCACCTCAGCCAGCTAAGCATGTCGTATAGTTCTCCTGGAACATCCCAACAACAG[C/T]AGGTCCCAGGACAGGGCACCTACACTCCCAGCTCTCAAGCTCCCCAACAGCACACCGCATATCCCCAGCAGCCCATGGTAAGTCACAGAAGAAGCGTCAAGTCAAGATCACTGCAGGTTCAGTGTTGCAGCAGTTCACATAGTTACTGTATATCCTTAATCTGTTTTTCTAGTTGCCGCTTACTTGTAATTGTACAATTACAGTGCAATTGTCCTGCTTAAGCAGTGTTGTTAGTACTCCTAACTAAAAGTCGCATACTATCTTGAGTAGGTGCTTGCTATGAATTACTTAAAAATTGTTTTATATTTTAAGTTTAAGTGTGATATGAGGATAATGGATGTAATACATTCAACATCAGTAGCATTACTGCACTGTCATTGGCAAATTCTCTACTCTTGCTTTGGTAAAGTGTTTATTAAATACATTATTCAGAAGTGTTAGGTCATTAGGATATTTTCTGCATACTCATTCGAGATAATATGGGTTTGGATGAATTTATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17370
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000012928 Nonsense 1209 1909 18 27
ENSDART00000132228 None None 202 None 3
ENSDART00000134887 Nonsense 404 1089 6 15
ENSDART00000146622 None None 201 None 4
Genomic Location (Zv9):
Chromosome 4 (position 7254573)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 8065792
GRCz11 4 8074421
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGTCACAAGTGCCCCCTCTCCAGCCGGTGACCACAACCATGCCAGTCGTG[C/T]AGCCCACACCAGTGCACAGCCAACCACAGACCACYACCGTGCCCAAKCAG
Long Flanking Sequence:
ACAACTCCATGCCCCCTCTGCTTCCTGCCACAACACCCTTGCCCTCTAGTGCCACCCCAGTGGTCTCTCCCCCAGTGTCTTCAGAAGTGACCTCTTCGCCATCTCTACCTTCTATAAACCCTCCAGTGTCATCATCTCCTCCTCCAACCGTCCCGGTCAATTCCGTAACCTCCCCTCCAGCACAACTCACCCTGCCTCAAAGTCAAGTTGCGCCTGCCGTCATCAGTGTTATTCCCACCCCTTCCACTCTGCCAATGCCAGCGGTGCCAACTGCCACATCCCTTCCACAAACTTCAGTCACCGTACCTTCCAGCACACCAATCGCTCCAATGGGATCAGTGTCCGGAGGCAGTGGAGAACAACCATCCATCCCTGCTACTTCTTCGCCCACTAGCGCTACAATCCAAACGCCACAGCTGGCACCATCCACCATCCCCACCACCACGGCTCAGTCACAAGTGCCCCCTCTCCAGCCGGTGACCACAACCATGCCAGTCGTG[C/T]AGCCCACACCAGTGCACAGCCAACCACAGACCACCACCGTGCCCAATCAGAGCCATGCGCATAGTGTTGAATGCGACAGTGACCAGCAGGGCAAGGTTGATGACATCCAGGCTCTAGATAAGAAGCTGCGCTCGCTCTTTATGGACTTGGGCTCCGGTCCCCCATCTGCCCAGTCTGATGTCACATCCGACCCGACGGCGACTCCAAGCGTTCCTGGCACCTCGTCTCCAACCACATGTGCCACCCCCAGCGGGACTCCACTCCCTCCCTCTAGTTTACCCCTGAACTCCTCCACTCAGTCTGCGGGGTCTCCCATGACCTCCATGGGCAATGCCTCCACCCCGGTCGGCTACAGTCAGACCACTCCATCCAAAGCTCCCTTAACACGATTACCGGTGAGTAAACGCTTCATCAAAAAGCCAAAAGGCAGCATGTGTCTGGGTTAAAGGCTGATCTCAAGACACCTGTCAATGTGTATAGGTGTATATGTCATTTTTAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33383
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000012928 Nonsense 1326 1909 18 27
ENSDART00000132228 None None 202 None 3
ENSDART00000134887 Nonsense 521 1089 6 15
ENSDART00000146622 None None 201 None 4
Genomic Location (Zv9):
Chromosome 4 (position 7254220)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 8065439
GRCz11 4 8074068
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCGGGGTCTCCCATGACCTCCATGGGCAATGCCTCCACCCCGGTCGGCTA[C/A]AGTCAGACCACTCCATCCAAAGCTCCCTTAACACGATTACCGGTGAGTAA
Long Flanking Sequence:
GGAGAACAACCATCCATCCCTGCTACTTCTTCGCCCACTAGCGCTACAATCCAAACGCCACAGCTGGCACCATCCACCATCCCCACCACCACGGCTCAGTCACAAGTGCCCCCTCTCCAGCCGGTGACCACAACCATGCCAGTCGTGCAGCCCACACCAGTGCACAGCCAACCACAGACCACCACCGTGCCCAATCAGAGCCATGCGCATAGTGTTGAATGCGACAGTGACCAGCAGGGCAAGGTTGATGACATCCAGGCTCTAGATAAGAAGCTGCGCTCGCTCTTTATGGACTTGGGCTCCGGTCCCCCATCTGCCCAGTCTGATGTCACATCCGACCCGACGGCGACTCCAAGCGTTCCTGGCACCTCGTCTCCAACCACATGTGCCACCCCCAGCGGGACTCCACTCCCTCCCTCTAGTTTACCCCTGAACTCCTCCACTCAGTCTGCGGGGTCTCCCATGACCTCCATGGGCAATGCCTCCACCCCGGTCGGCTA[C/A]AGTCAGACCACTCCATCCAAAGCTCCCTTAACACGATTACCGGTGAGTAAACGCTTCATCAAAAAGCCAAAAGGCAGCATGTGTCTGGGTTAAAGGCTGATCTCAAGACACCTGTCAATGTGTATAGGTGTATATGTCATTTTTAGTCACTATTATAAGTATTTCAGAAATAAATTAAGCCTATTTTTTAGGTAGAATTATCATTTATTTCGTTTGTATTGTGACTTTATTTTTGGTAAAATGACACTGACACTTAACAGCGGTGTGATGCACAAAACAGAAACAAAAGTATAAAAATGTTGTTGTAAATACTTGCATTACTTGTTTAATAGTTTTAAATTTCAAATGTTAAATATTTAAATTTTTGTTTAATTAAAAAATAACTTTTCTAGGCAGGATAATTTACATTTATTATTACATAATAGTAAAAATTTACATTTATATCTTTTGACACATTAAATTAAACAAAATTCAGAAACAATTTGTAAATTATTTTAATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33382
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000012928 Nonsense 1338 1909 18 27
ENSDART00000132228 None None 202 None 3
ENSDART00000134887 Nonsense 533 1089 6 15
ENSDART00000146622 None None 201 None 4
Genomic Location (Zv9):
Chromosome 4 (position 7254186)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 8065405
GRCz11 4 8074034
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCACCCCGGTCGGCTACAGTCAGACCACTCCATCCAAAGCTCCCTTAACA[C/T]GATTACCGGTGAGTAAACGCTTCATCAAAAAGCCAAAAGGCAGCATGTGT
Long Flanking Sequence:
CCACTAGCGCTACAATCCAAACGCCACAGCTGGCACCATCCACCATCCCCACCACCACGGCTCAGTCACAAGTGCCCCCTCTCCAGCCGGTGACCACAACCATGCCAGTCGTGCAGCCCACACCAGTGCACAGCCAACCACAGACCACCACCGTGCCCAATCAGAGCCATGCGCATAGTGTTGAATGCGACAGTGACCAGCAGGGCAAGGTTGATGACATCCAGGCTCTAGATAAGAAGCTGCGCTCGCTCTTTATGGACTTGGGCTCCGGTCCCCCATCTGCCCAGTCTGATGTCACATCCGACCCGACGGCGACTCCAAGCGTTCCTGGCACCTCGTCTCCAACCACATGTGCCACCCCCAGCGGGACTCCACTCCCTCCCTCTAGTTTACCCCTGAACTCCTCCACTCAGTCTGCGGGGTCTCCCATGACCTCCATGGGCAATGCCTCCACCCCGGTCGGCTACAGTCAGACCACTCCATCCAAAGCTCCCTTAACA[C/T]GATTACCGGTGAGTAAACGCTTCATCAAAAAGCCAAAAGGCAGCATGTGTCTGGGTTAAAGGCTGATCTCAAGACACCTGTCAATGTGTATAGGTGTATATGTCATTTTTAGTCACTATTATAAGTATTTCAGAAATAAATTAAGCCTATTTTTTAGGTAGAATTATCATTTATTTCGTTTGTATTGTGACTTTATTTTTGGTAAAATGACACTGACACTTAACAGCGGTGTGATGCACAAAACAGAAACAAAAGTATAAAAATGTTGTTGTAAATACTTGCATTACTTGTTTAATAGTTTTAAATTTCAAATGTTAAATATTTAAATTTTTGTTTAATTAAAAAATAACTTTTCTAGGCAGGATAATTTACATTTATTATTACATAATAGTAAAAATTTACATTTATATCTTTTGACACATTAAATTAAACAAAATTCAGAAACAATTTGTAAATTATTTTAATTTAAAGATGTACTTTTGTAATAATATTTATTGGTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa45163
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > C
Consequence:
Essential Splice Site, Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000012928 Missense 1675 1909 25 27
ENSDART00000132228 None None 202 None 3
ENSDART00000134887 Essential Splice Site 855 1089 13 15
ENSDART00000146622 None None 201 None 4
Genomic Location (Zv9):
Chromosome 4 (position 7244187)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 8055406
GRCz11 4 8064035
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCCAGCAACCAGCACTTTATCAGCACAGAGCGCCCCTTCTGTGTACCCA[G/C]CCCAGCAGGCCTTCCTGGCCCCCGGGGGGATGATGGATGGGGGGAGCAGC
Long Flanking Sequence:
TGAATCACACCAAGAACAAAAAGCAACATTGTCACAATTTGAATCCCCGTTTTGGAACAAAACAATCGATCTACAGGTGTGAAAGCTCCCTAAGATTTGATTTCAATAGGCCCCTCCTTAAAATCCCTAAGTGCTTTGATTGGCCTGCTTGACTCAGTGTGTTGTGATTGGCTGACCAGCTTGACTCCGAACACCTTAAGTGTGTCATAAATGTAACACCTTTGCCATAATCATGAGTTTTAGCTTCCAAAGGTTTCAATACAGTGTAAACACAAATGTTTTATATTGAAATCGGAATCCATATGATTTCGATCATGTAAAGTTTTGATTAGTCAGTAGGATTTTTTTTTTCACTTAGATTTTTCTCACCTCTAGCATCAGCAACTTTGAATCTGTTTTTGTCACATGCCTTAATATTTCTATATATGTTTGTGTTTTTTTTCCATGGTCTTCCAGCAACCAGCACTTTATCAGCACAGAGCGCCCCTTCTGTGTACCCA[G/C]CCCAGCAGGCCTTCCTGGCCCCCGGGGGGATGATGGATGGGGGGAGCAGCCCTCTGCTGCAGTCTTTCAAACCCTCGCCCTCCAATGACAACCTGTGCTCCACTTTCACCAGTGACGCCACGCTCTCTGCGCCCAGTCTCTGTGTAACCTCGCAAGGTAAAAATAAAGAGACCTAACACAACACAGCCCTCGCTTGATCCTGAGCTTTTTCTACTTGTTTTTTAATCCACTCCAAGTAGCACATATTAAAATAAAGTGACATTAGGAGACACTTTAAATGCAAGCAAAAATATTCAAAAAATAGAGATATTTAAATCACATTCTCAGTTTATGATTTATAGTTATGTGTTTATAGTTTGTGTATTGTTAATTACATTTAATTTTACTTAAATTCAATTATTTTATATTTATTACAATTAAATTGCAATAACAATTTAAGTTTTTTTTTTTTTTACAATTAAATCATTGTATTTACAATAAAATGTAAATAATGGTAAACT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16047
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000012928 Nonsense 1849 1909 27 27
ENSDART00000132228 Nonsense 142 202 3 3
ENSDART00000134887 Nonsense 1029 1089 15 15
ENSDART00000146622 Nonsense 169 201 4 4
Genomic Location (Zv9):
Chromosome 4 (position 7229251)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 8040470
GRCz11 4 8049099
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TCTCTAGGAGMTCGGAAGGGCTCCTTGTGTCCCACGCCGCAGTACGGCTA[C/A]CCCTCCGCACCTTACAGCGCCCAGTGGGCTGGAGCGGCCACGCACACCCA
Long Flanking Sequence:
ATCAGCTGCCGACCGGAAGTTCTTCGCATTCTCCTTGCGCATACACGCAAAGCATAATGGGTAATTTTGCGTTACAAGAAAAAGGTCTATAGGTTATGAATAAAATATGCTCATTCTAATAGTGTTTAAAATTGAATTGAATTGCAAATGAATTATATCCCCACCTTCATTGTCCCGACCCCCACTTTAGGTACCACTGATATAATGCAAATAAAATACCAGCATAGTTGCTTAGATTCCAAATTTGTTTGTAAAACATCACTACATTTTATACTTTCTGTATAAACTCAGACCTTAAGTCCTGCCTTTCTCTAAATTCTTAATTTCTTTTCTCTTCAGATGGTTCCTCCAGTAAACATGGGCCGTAAGTACTCAGCTCCGGGTCAGCTGTGCCCAAGCATCGCTTCAACTCTGAGCGGCCATCCACCAATGCCCAACACTCCCGCTACCTCTCTAGGAGCTCGGAAGGGCTCCTTGTGTCCCACGCCGCAGTACGGCTA[C/A]CCCTCCGCACCTTACAGCGCCCAGTGGGCTGGAGCGGCCACGCACACCCAGGCCGGTCTGCTGGCCACCTCACAACCCCTGGGCCAATATCCCCAGGTGCCCACCCCTTTACAGACCTTCCACATCAGCACTTTGCAAAAGTCAGTCAGCCACCCGGGCGGACCCAATCTGAAGAGCACGTAGGGCAGGGCCTAGCCGCGCCAGGCCTATAATAACTGTTGGGGATTGAGGCAAGGGTAGGGGTGCAGACTGAAAGTGGGTCTGGGCAAGCATCCTGCATGCTCACAAATATGCCACGGGGATGATGCAAGGGATAAGAGAAGACGAAAACAAAGCAACGGACACTTGAGTGCAATGTTACGTGGCCAAAGAAGGTGTGACCATTTTTGCATCCTTCACCAAACATTTGTCAAGGGGTTTGACTTGTGTTTTCAGACCGAATGAATGCCACCTCCATCCATCCATCTGTGATATAAGCATTCAGAGGTGGGGTGGGTGAT
Associated Phenotype:
Not determined