Busch Lab

ZMP

LOC792371

Ensembl ID:
ENSDARG00000077654
Human Orthologue:
GRM8
Human Description:
glutamate receptor, metabotropic 8 [Source:HGNC Symbol;Acc:4600]
Mouse Orthologue:
Grm8
Mouse Description:
glutamate receptor, metabotropic 8 Gene [Source:MGI Symbol;Acc:MGI:1351345]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa40206 Nonsense Mutation detected in F1 DNA Not yet available
sa33363 Essential Splice Site Available for shipment Available now
sa33364 Nonsense Mutation detected in F1 DNA Not yet available
sa7554 Missense Mutation detected in F1 DNA Not yet available
sa8697 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa40206
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109044 Nonsense 409 909 6 10
Genomic Location (Zv9):
Chromosome 4 (position 3546469)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 3662171
GRCz11 4 3675498
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTAGTTATGAGCAGGAAGGAAAGGTTCAGTTCGTGATGGATGCAGTGTA[T/A]GCGATGGCTCACGCTCTCCACCGAATGCACAGGGAATACTGCTTCGGTTA
Long Flanking Sequence:
TTAAATTAAATTAAATTAAATTAAATTAAATTAAATTAAATTAAATTAAATTAAATTGACTTAAACCATTAAAATAATTAAAATGAAAACAATTAATAAAATTAATAAAACTCTTTTTTCCCCCTATTTCTCCTTTCACTTAATTTAAAATTATTGCCATTTCAAACATTAATCCTTTATTTTATGTCATGTTGATTTTAGTTATTTATTTTTAATGCAATTCCAACGTTTGGAGTCCGTAATAAGTAATGATAAGTCAGTAATAGGTACGTCCAGTGTTGTGTTCGTATTTATGTGTATTAATGGTTTAACATTGCATTCCACTATATGTCCACACATGTAGAGGAATGACAGTAAAGCTGACTTTACTGAAATGTGAGGGTCTGTATTGTGTGTTTGCTGAAGTTTTTTGTGTGTGTTTGTGCAGGGCTGGAGAAAGTGGGCCGGGACTCTAGTTATGAGCAGGAAGGAAAGGTTCAGTTCGTGATGGATGCAGTGTA[T/A]GCGATGGCTCACGCTCTCCACCGAATGCACAGGGAATACTGCTTCGGTTATCCCGGACTCTGCCCTCGCATGAGCAACATCAATGGGAAAGAGCTGCTGGGATATATACGCAACGTCAGCTTCAACGGTGAGTGGCTCGAAAGAGCATTTAGAGCACTTGGGTTCAAGCCTAAAATTATTTTTAAAAAGTAGACTTAAAACAATGAGAATACTGTAAGTCCAGAAGTAAGGAAAAAACAATTAGATTTAGATTAGATTAGATTTACAAAAAAACAATAACAAAAATGGTTCAATTTAATTTAATTAAATAAAAAAAAATTCTAGTAGTGAAGAAAAATTTTATTTTATCTGAAATTGAATACAATTTTATCAGATTTAAAAAATAAAATAAAATAAAATTAGTTCAATTGAATTAAATTAAATAAAAAATAAGAAATTAGAATAAACAATAAGAATAAATCCAGACGTAAATTAAATTAGTGAATAAATACAATATTATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33363
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109044 Essential Splice Site 498 909 7 10
Genomic Location (Zv9):
Chromosome 4 (position 3570903)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 3686605
GRCz11 4 3699932
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGCTGAGTACAAAGTGATCGGCCAGTGGACAAACAAACTGCATCTAAAC[G/T]TGAGTAAAAGAGATTTTCCTGCTCGTCCATGCATTCAGGGGTTTTTTTTG
Long Flanking Sequence:
TGTATCAGAAATAATAAAGAAATAAGAATGTAAAAAAAAAACAGAAAATGCACTGACAGTTTATTACAAGGGTTTTGTAGCATAATACACAACACCAACCCAGACAATATAGCACTGCAAACTATTGAAAATGTTTATAAAAATCCTTTTTTACAACTATTGAAGGTTAAAAGTTGTTGGAAGAAAGATCAAGCTCCCATAATGCAGTTCAAAAGCCGAAAGAAATGGATGGAAAAAATCACAAATCACATTAATCACAAAATATGAAACACTGCTAGTTTATGCATATTTGTTACTGTGCATACAGGACAAAAAGCATGGATTGACTGGCTCGTCAACACGTCATATCTTGTTTTACAGGAAGCGCAGGAACTCCAGTGGTCTTCAATCAGAACGGAGATGCACCAGGACGATACGACATCTTCCAATATCAGATCACCAACAAATCCACAGCTGAGTACAAAGTGATCGGCCAGTGGACAAACAAACTGCATCTAAAC[G/T]TGAGTAAAAGAGATTTTCCTGCTCGTCCATGCATTCAGGGGTTTTTTTTGTCTTCCCAGGGTGCAATGATGTTTGTGTGTCCACATCTGATACATTCAAGCGTAAATGTTTGCAATCTTATCTTTTTTCCCGATGATGCATGTGACACGAATACTCCCGGGCCTTCATTAGTCAACGAGATGGAAGATAAGCTTGTAATGTGTTATGCCTGGCTGCGAAGCAAATTTAATGGAGCCAGAAACGAGTCGTGGTTTCATGGCCAAAAGCTCTCGCAGCAGAGGAGAGATTGAAGCTGTCATTTTCTGATACGTGATGGAGAAACCCTAGCTCCTCTGGGCTTTTGTGTCTGTGCAGGTGAGTGGGAGGAAAAAAAAATCACTTAGAAGAATTGTGATACTGCCCTTCAAAAAAAAAAAAAAAAAATCCTGTAAATCTCACTTCTTAACTACACTGATAAACCCTCTTTAAAGTTCACATGAACTGGAAGTGGGGCAGCAGGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33364
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109044 Nonsense 526 909 8 10
Genomic Location (Zv9):
Chromosome 4 (position 3578298)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 3694000
GRCz11 4 3707327
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCAGACTTCCAGCTTCAGTGTGCAGTGTGCCATGTCAAATGGGTGAACGT[A/T]AGAAGATCGTGAAGGGTGTGCCCTGCTGCTGGCATTGTGAGCGGTGCGAA
Long Flanking Sequence:
TAGACTATTTCCAGTTGGTTGCTAGAGTGTTTTGGCCATTTTCAGGATGTTATAGCATTTCTGGGTGGTTGCGTTTTCTTGAGTGTTAAAGTATTTCATTAGCATGTATAGGCTATTTGCTAGGGCGTTATCATTTCTAAGCAGTTGCTCTTGTATTCTGGGCTTTTTATCATGCTATATACTATTTGTTGGTGGTTTGTAGGGTTTTCTGAATTTTTTTAGCATGTTCTGTATTCAGTTTCCTGGCCATTTTAAGTTGTTCTGGGTATTTAAAGCATGGTTGCTGAGTTGCTCTGTGTGTGTGTGTGTGTGTGTTATGCACATGTGACCAGTTAGACTTGCTTGAATGAGCAGTTATTTCGCCGTACGTGTCCGCTCTTCACTTTTATTTGATGGGACATTTTTGTTTTCTTCTGCAGGTGAATGTGATGCGCTGGCGGACAGGCGACCCCAGACTTCCAGCTTCAGTGTGCAGTGTGCCATGTCAAATGGGTGAACGT[A/T]AGAAGATCGTGAAGGGTGTGCCCTGCTGCTGGCATTGTGAGCGGTGCGAAGGCTACCACTTCCAGGCCAGCGAGTTCAGCTGCGAACTCTGTCCTTATGAGCAGCGTCCAGACCGCAACCGCACCGGCTGCGTCCCCATCCCTATCATCAAACTGGAGTGGCATTCAGCTTGGGCAGCCGTGCCGGTGTTCGTTGCTGTTCTTGGCATTTTGGCCACCAGTTTTGTAGTGGTCACTTTTGTCCGTTACAATGATACCCCAATTGTCCGTGCATCTGGACGAGAGATGAGCTACGTCTTACTGACAGGTATTTTCTTATGTTACGCCATCACCTTCTTGATGATCGCCACCCCCAGTTTAGGCATCTGCTCCTTCAGGCGGGTGTTTCTTGGATTGGGCATGTGCTTCAGCTACGCGGCTCTACTAACCAAAACCAACCGTATCCATCGCATTTTTGAACAAGGAAAAAAGTCAGTGGCCGCTCCACGCTTTATCAGCCCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa7554
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109044 Missense 541 909 8 10
Genomic Location (Zv9):
Chromosome 4 (position 3578343)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 3694045
GRCz11 4 3707372
KASP Assay ID:
554-4206.1 (used for ordering genotyping assays)
KASP Sequence:
AACGTAAGAAGATYGTGAAGGGTGTGCCCTGCTGCTGGCATTRTGAGCGG[T/A]GCGAAGGCTACCACTTCCAGGCCAGCGAGTTCAGCTGCGAACTCTGTCCT
Long Flanking Sequence:
GATGTTATAGCATTTCTGGGTGGTTGCGTTTTCTTGAGTGTTAAAGTATTTCATTAGCATGTATAGGCTATTTGCTAGGGCGTTATCATTTCTAAGCAGTTGCTCTTGTATTCTGGGCTTTTTATCATGCTATATACTATTTGTTGGTGGTTTGTAGGGTTTTCTGAATTTTTTTAGCATGTTCTGTATTCAGTTTCCTGGCCATTTTAAGTTGTTCTGGGTATTTAAAGCATGGTTGCTGAGTTGCTCTGTGTGTGTGTGTGTGTGTGTTATGCACATGTGACCAGTTAGACTTGCTTGAATGAGCAGTTATTTCGCCGTACGTGTCCGCTCTTCACTTTTATTTGATGGGACATTTTTGTTTTCTTCTGCAGGTGAATGTGATGCGCTGGCGGACAGGCGACCCCAGACTTCCAGCTTCAGTGTGCAGTGTGCCATGTCAAATGGGTGAACGTAAGAAGATCGTGAAGGGTGTGCCCTGCTGCTGGCATTGTGAGCGG[T/A]GCGAAGGCTACCACTTCCAGGCCAGCGAGTTCAGCTGCGAACTCTGTCCTTATGAGCAGCGTCCAGACCGCAACCGCACCGGCTGCGTCCCCATCCCTATCATCAAACTGGAGTGGCATTCAGCTTGGGCAGCCGTGCCGGTGTTCGTTGCTGTTCTTGGCATTTTGGCCACCAGTTTTGTAGTGGTCACTTTTGTCCGTTACAATGATACCCCAATTGTCCGTGCATCTGGACGAGAGATGAGCTACGTCTTACTGACAGGTATTTTCTTATGTTACGCCATCACCTTCTTGATGATCGCCACCCCCAGTTTAGGCATCTGCTCCTTCAGGCGGGTGTTTCTTGGATTGGGCATGTGCTTCAGCTACGCGGCTCTACTAACCAAAACCAACCGTATCCATCGCATTTTTGAACAAGGAAAAAAGTCAGTGGCCGCTCCACGCTTTATCAGCCCTGCTTCCCAGCTGGTCATCACCTTCAGCCTGATCTCAGTTCAGTTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8697
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109044 Essential Splice Site 810 909 8 10
ENSDART00000109044 Essential Splice Site 810 909 8 10
Genomic Location (Zv9):
Chromosome 4 (position 3579154)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 3694856
GRCz11 4 3708183
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTTAGCTTTTATACCAATCTTCTTTGGCACTGCACAATCGGCGGAAAGGG[T/C]AAGTGTGATTTAAGAAATTCCTTAATGAAATAYACTGAATTTAATGCYAT
Long Flanking Sequence:
TTTAGGCATCTGCTCCTTCAGGCGGGTGTTTCTTGGATTGGGCATGTGCTTCAGCTACGCGGCTCTACTAACCAAAACCAACCGTATCCATCGCATTTTTGAACAAGGAAAAAAGTCAGTGGCCGCTCCACGCTTTATCAGCCCTGCTTCCCAGCTGGTCATCACCTTCAGCCTGATCTCAGTTCAGTTGCTCGGTGTGTTTGTGTGGTTTGCTGTTGATCCTCCACATACAGTGGTGGACTATGGCGAGCAGCGCACGTCTGATCCAATGAAGGCCCGCGGGGTCCTAAAGTGCGACATCTCGGACCTGTCGCTCATCTGTTCTCTGGGCTACAGCATCCTTTTGATGGTCACATGCACTGTTTACGCCATCAAGACCCGTGGCGTGCCAGAAACTTTCAACGAGGCCAAGCCAATCGGATTTACTATGTACACTACCTGCATCATTTGGTTAGCTTTTATACCAATCTTCTTTGGCACTGCACAATCGGCGGAAAGGG[T/C]AAGTGTGATTTAAGAAATTCCTTAATGAAATATACTGAATTTAATGCTATTGCAAATGTTTGTTTTGGTGTCACTTCACAATAAGGTTGTATTAGTTAATGCTACTTAATGCATTTACTAACATATTTACTACTTTTAATATATATTTTTGTTATCAACAGTTATGCAGTTGTTATTTACCTCTAAATGGGGCTGTTTTTGTACGGTTAAATGACTTGTTGGGGTTTGTTAACTTAAGCATGCGCCCTGAAAGAAATTTCAGTCATTGTTTACTCACTCTCATGTCATTTAACGTTATTAAACTGAGAGGGAGAAAAAAAAAAGATTTGTAAAGTTCACTGCCTGACCAAATCACCATTTGGGAGCCACATGCATCTCTCGTATGACTGATATGCTTAAATTGATTTATGTTAGTATTAAAATTGTTTATGTGTATTATGAACAAACAACGAGCAGTACATTTATTGTAGTATTTGTTCATGTTAGTTAATGAAAATACA
Associated Phenotype:
Not determined