ZMP

srebf1

Ensembl ID:

ENSDARG00000067607

ZFIN ID:

ZDB-GENE-090812-3

Description:

sterol regulatory element-binding protein 1 [Source:RefSeq peptide;Acc:NP_001098599]

Human Orthologue:

SREBF1

Human Description:

sterol regulatory element binding transcription factor 1 [Source:HGNC Symbol;Acc:11289]

Mouse Orthologue:

Srebf1

Mouse Description:

sterol regulatory element binding transcription factor 1 Gene [Source:MGI Symbol;Acc:MGI:107606]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa33346	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa18770	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa33346

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000092665	Essential Splice Site	277	1104	5	25

Genomic Location (Zv9):

Chromosome 3 (position 62735165)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	3	61837319
GRCz11	3	62073959

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CATTACAACACTCACGTCTACAGCGCCGGTCCAGAACACCCCACTGCAGG[T/C]TCCCCCGCACACACATTCACACTAAGAATAACAGGAGGGCAAAAAACATT

Long Flanking Sequence:

GTCTGCTTTTGAAATATCTGTTAATATTCACCCCCTAGTGGCCGTCATAGGGAATTTATTAACAACATTATTTATTTTTTATTTAATTAAATATATCCTTAACTTGTTTGTCATTATATATTCAGATATAGTTAGTGTTTAGTGTTGAATTTATGATATTTATACATATTTATACATATGTATAATATACTGAATAACAATAATGGTCACACTTTACAATAAGGCTTCATTATGTATTCACTAATGTAGTAATAATGAGCAATATTTATACATGTTTTAATATATTTTCTGAGCATTGTGTGTGTTTGTAAAGCAGCTTTACGTGCCGGTGAGATCATATCATGTGTTTTTGCAGGTTTTGTTGCAGCCGCAGTTCATTAAGGCCGACTCTCTATTGCTCACAACTCTGAAACCGGACGTGACAATGGTAACGACAGTAGCATCGCCCTGCATTACAACACTCACGTCTACAGCGCCGGTCCAGAACACCCCACTGCAGG[T/C]TCCCCCGCACACACATTCACACTAAGAATAACAGGAGGGCAAAAAACATTGACTGCCATGTAGAATGCGAATTTAAATAAAGAAATGTATTGTTATTTTTACACTTTGCATTGCGGTTTTACATATTACACTTTAAATTGCATGTGTATTATGTAAAAACCGCAATGTAAAGGGTAAAAATAGCAGGTCCATCTCAGTTTATTTGGTAAGTGTGACCTGCTGATTCCAATATTTACTGATTCCAATTTTTTTCTAAAAGAAGAGAAAAAAGAGGAATCTGAATCGTCAAATATCGGTATCGGCAGGTCACACTTACCAAAAACACTGAAATCAGAATCAGTAAATATCGGTATCGGCAGGTCACACCAAAAAAAAAGGAATCAGTAAATATCAGTAATGGCAGGTCTTGCTTACCAAAAAAACTGAAATCGAAATTGTCAAATATCGGTATCGGCAGGTCACACACACACACAAAAATGAAATCGAAGCTGTCAAATATC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa18770

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000092665	Nonsense	853	1104	16	25

Genomic Location (Zv9):

Chromosome 3 (position 62725893)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	3	61828243
GRCz11	3	62064883

KASP Assay ID:

2259-4263.1 (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GACCCGCACTCTAAGTGGTGGTCTTCAATGGTGGTGGTGGTCATTAATTG[G/A]CTGCAGGGAGAGGACGCGGCGGCCGAGAGGCTGTACCCTGCGGTGGAGCA

Long Flanking Sequence:

GTGGAGTTTGTAACCAAATTTGAGTCATGTTTAGTTGCTAAATGTAATAGAAGTTCATTTTGATGCGACTTTATTTTGCATTCGCTGCCCGTAACGCTTTTAAATCTGCCTCATCTGTGTTTATTTGAATATAAGTGTATTCATTTGAGTGTGTGTGTGTGTGTGTGTTGACAGCGAGTTCTCCGACGCTCTTGAATACCTGCAGTTGCTGACCAGCGCTGCTGATGCAGCCGGAGCCACGACACAATCCTTCGCCATCGGCTCCAACATGGCCACCGTCACAGGTCAGCTTCACACACTGCTCTATAATATCCACACATCAGAGAGTAACAGCACTGCTGGCTGAAGGGAAGACATGGGGACGGGGTAAAAAGCAGCAACTGGGCCTAAAGTTTCACTGAAGCAGAAGTGTGTGTGTGTGTGTGTGTGTGTTCTTGACCTCCAGGCTGTGACCCGCACTCTAAGTGGTGGTCTTCAATGGTGGTGGTGGTCATTAATTG[G/A]CTGCAGGGAGAGGACGCGGCGGCCGAGAGGCTGTACCCTGCGGTGGAGCATTTACCACGCAGCCTGCAGTCCGCCGAGTGAGACGCTTCCCCACACTCTGTCTGTCTGTCTGTGTGTGTGTGTGTGTGTGTGTTTATCTGATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTCTGATGTGTGTGTGTTTCTGTTGTATGTGTGTGTGTGTGTGTGTGTTTCTGTTGTATGTGTGTGTGTGTTTCTGATGTGTGTGTGTGTGTGTGTGTTTGTTTCTGATGTGTGTGTGTGTTTCTGTTGTGTGTGTGTGTGTGTGTTTCTGATGTGTGTGTGTGTGTGTGTGTGTTTGTTTCTGATGTGTGTGTGTGTTTCTGTTGTGTGTGTGTGTGTGTTTCTGATGTGTGTGTGTGTGTGTGTGTGTGTGTTTCTGTTGTGTGTGTGTGTGTGCGTGTGTATGTGTTTCTGTTTGTGTGTGTGTTTCTGATGTGTGTGTGTGTGT

Associated Phenotype:

Not determined