Busch Lab

ZMP

nsfa

Ensembl ID:
ENSDARG00000007654
ZFIN ID:
ZDB-GENE-030616-37
Description:
vesicle-fusing ATPase [Source:RefSeq peptide;Acc:NP_001037793]
Human Orthologue:
NSF
Human Description:
N-ethylmaleimide-sensitive factor [Source:HGNC Symbol;Acc:8016]
Mouse Orthologue:
Nsf
Mouse Description:
N-ethylmaleimide sensitive fusion protein Gene [Source:MGI Symbol;Acc:MGI:104560]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa33227 Nonsense Mutation detected in F1 DNA Not yet available
sa44566 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa33226 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa33227
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000103043 Nonsense 76 744 4 21
Genomic Location (Zv9):
Chromosome 3 (position 34869514)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 34654710
GRCz11 3 34784218
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTCTTCTTAACCCTTCTTAAAGAGGAAATGGGCAGGCCTGTCCATTGGG[C/T]AAGAAATAGAAGGTGTGTATATTATTCCTGGAGAACATTTAGAACACAGT
Long Flanking Sequence:
TTGAAGGGGCGTCATGGTGGCTCAGTGGTTAGCACTGCAAGAAGGTCTCTGGTTTGAGCCCCAGCTGGGCCAGTTGGTGTTTCTGTGTTGAGTTTGCATGTTCTCCCCATGTTTGTATGGGTTTCCTCTGGGCGCTCCGGTTTCCCCCCACAGTCCAAAGACATGCACTATAGGTGAATTGAATAAGCTTAATTGGCCGTAGTCTATGTGTGTGAATGTGAGTGTTTGGGTGTTTCCCAGTGCGGGGATGCAACTGGAGGGGGATCCGCTGAGTAAAACATATGCTGGATAAGCTGGCAGTTCATTCCGCTGTTGCCACACTTGATAAATAATGGGAATAAGCTGAAAGAAAACAAATGAATGAACAAGTTTTGAATTATATAAGTGATGAACAAATATTCATTATTGTCTGAACATTATATTTTGATGGACCTTTTACATGTTATTCACTCTCTTCTTAACCCTTCTTAAAGAGGAAATGGGCAGGCCTGTCCATTGGG[C/T]AAGAAATAGAAGGTGTGTATATTATTCCTGGAGAACATTTAGAACACAGTTCAATTCAGCACACAATTCAAATCACTGATTTTATTCCCACCATTTCAGTGTCAAACTACAACTTTGACAAGTCCAGGCAGTGCATTGGTGCCATGACCATTGAGATTGACTTCCTGCAGAAGAAGAGCACAGACTCCAGCCCTTACGACTCAGACAAAATGGCTGCTGAGTTCATCCAGCATTTTAACAATCAGAGCTTCTCCGTGGGGCAGCAGGTCAGAAACACATCACCAAAACTAAATGATTTACAAAGAGCTGAAAATCAATAAATGTTTTGAAAAATAATTCCTGCATAAGTTTTGAGATTTTCATAATGAACCGCTCTTGCCTTTTGAGTCGATTCTGTTGTTAACAGCATATGACGCTGTATGCTTTACAAACTGCTGGACTCTGCTATTTCTGCTAAGTATGTTACCCACAGCCAATATCTCAGACCATAATCTTAGAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44566
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000103043 Essential Splice Site 248 744 8 21
Genomic Location (Zv9):
Chromosome 3 (position 34866616)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 34651812
GRCz11 3 34781320
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGGGCCTTTGCCTCTCGAGTCTTTCCTCCAGACATTGTGGAGCAGATGG[G/A]TATGTGCTGTTTGTTCCTTTCATAATAAAAGTCATCCATGTTCCAGAACA
Long Flanking Sequence:
AGCTCTTCGGCCTACTTATCAAAGATATTGAGGCGATGGATTCCAGCATTCTGAAGGGTGAACCAGCATCTGGCAAAAAGCAAAAGGTGTCAGAAAGTGCATATTAAATTTGCACTTTAATATTACAGAAAGAAATGATCCATTAATTTGTATACATATCTAATCGTCCTGTGTAACATCACAGATTGAGGTCGGCCTGTTGGTTGGAAACAGTCAAGTGATTTTTGAAAAATCAGAGAGCTCATCTCTCACTCTAGTTGGTGAGTTTTATCAGACTTTAAATAATACATTTCCATTCACTGTCATATAAACAGCTTCTTAATCTTACTCTTTTTGCCCTCCAGGCAAGGCTAAAACTAAAGAAGCCCGTCAAACCATCATCAACCCTGACTGGAACTTTGAGAAAATGGGCATTGGTGGTTTAGACAAGGAGTTCTCTGATATCTTCCGCAGGGCCTTTGCCTCTCGAGTCTTTCCTCCAGACATTGTGGAGCAGATGG[G/A]TATGTGCTGTTTGTTCCTTTCATAATAAAAGTCATCCATGTTCCAGAACAGGAAAATGCAAACATCTTCATCTTCTACATTGATGTTTATAATCATATTGTGCTAATGTAGAAGTATATTTATCTAGTGTAAAAGTGAGATGTTGTTTGTTCTGCAGGTTGTAAGCATGTGAAAGGTATCCTGCTCTTTGGTCCTCCTGGCTGTGGTAAAACACTGATGGCCAGGCAGATCGGTAAAATGCTAAATGCCAGAGAGCCAAAGATAGTCAACGGACCAGAGATCCTCAACAAGTACGTGGGAGAGTCTGAGGCCAACATTAGGAAACTGTTCGCGGATGCTGAGGAGGAACAGAAAAGGGTGAAAAGTTTCTCCTCACAAATACACTGTCCTACTATATTATAATCTCTTCTGTGTCTTAATTGTAATGTTGTGTGTGTTTTTGTGCAGTTGGGTGCTAACAGCGGTCTGCACATCATCATCTTTGATGAACTGGATGCCAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33226
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000103043 Essential Splice Site 587 744 15 21
Genomic Location (Zv9):
Chromosome 3 (position 34862182)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 34647378
GRCz11 3 34776886
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACAAGATGATCGGCCACTCAGAGATCTCCAAATGCCAGGCAATCAAGAAG[G/T]TTAGTGGTTAACATACAGTATAGTATCTCACAAATACATTGAAGAATATA
Long Flanking Sequence:
GCTGGCAAACACATTAATGTACATATATATTTTAAATGAAAAGAAAAATCTAATATGGGGAAAATATTGTAGTTTTGGACAGAGTAGATTGCTTGCAAGGTTAATTGATAACAATCTTTATGTCAAATATTCATTGACTAAAACTAGACTAAAACGTCAGAACTTTTAGTGGTCTAAAACTAGACTGAACCTACAATGATTCAGAAGACTGTAATATGATTAAACTAAATCTAAAATATGCTGCCAAAATGAACACTGGCTCAAACACTGCTGTATTACAAATCCTCAGGCTTTCAAATGCCAATAACTGTGTTTATATACAGTATGTGTTTATATATTACATGAAGTTTTTGTTTTTCCCGTCAGGACCTCCTCACAGTGGAAAGACAGCTCTGGCTGCCAAAATCTCAGAGGACTCGCAGTTCCCATTCATTAAGATCTGCTCTCCAGACAAGATGATCGGCCACTCAGAGATCTCCAAATGCCAGGCAATCAAGAAG[G/T]TTAGTGGTTAACATACAGTATAGTATCTCACAAATACATTGAAGAATATAATGATTTAGAGTCTATTCACAGTTTTATCAGCCTTCTCATACACAAAGTAGTTGCATTGCATCATTTAAAATTTTAATTATTATTTACTTTTCAGATCTTCGATGATGCCTACAAGTCTCAGCTCAGCTGTGTCGTGGTTGATGACATTGAGCGCCTCTTAGGTTAGACATTTGCTATTTACAATTAAAAAATTATTATTATTATTGTCGATTAATTGTTTTTTTCAAGAATGGCTCTTAAATGGGAAAATTTGTTGAATTAATATAACAAATTACATTTTTAAAAAACATTAAAATAAAACTAAAGTTTTTTAAATATATATTAAAGTATATAATATAATATAATATATAATATAATTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATTCAAGTATAATAATATA
Associated Phenotype:
Not determined