Busch Lab

ZMP

e4f1

Ensembl ID:
ENSDARG00000038243
ZFIN ID:
ZDB-GENE-050913-103
Description:
Transcription factor E4F1 [Source:UniProtKB/Swiss-Prot;Acc:Q4V8R6]
Human Orthologue:
E4F1
Human Description:
E4F transcription factor 1 [Source:HGNC Symbol;Acc:3121]
Mouse Orthologue:
E4f1
Mouse Description:
E4F transcription factor 1 Gene [Source:MGI Symbol;Acc:MGI:109530]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa40034 Nonsense Mutation detected in F1 DNA Not yet available
sa40033 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa44561 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa33133 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa40034
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000055767 Nonsense 185 719 5 14
Genomic Location (Zv9):
Chromosome 3 (position 18550779)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 18579141
GRCz11 3 18728881
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTGCGAAACAGCGTTCAGGACCAAGGGCTCGTTAATCAGACACAAACGT[C/T]GACACACGGGTATGTCTAAGCTCTGTGAGACTGTGTCATTATACTGGACT
Long Flanking Sequence:
AGACTGTAGATCAGCAAAAATACCAGATGCAAACAAGGCCAAAAAATGATCCGCTCACCATAGTTATATACAGTATCAACTCTTCAAGGAGATCAGCTTATTTTATTTTTAACATGATTCACCGATCCATTTTTTTTAACTCTCTTTATTCCTTTAGAGAAGCAACATGCAAAGGTGGCATCTGGAGACAAAAAGAGAAGCCGCTCTACAAGCGAGGATGAAAGTTCCAGTCCTTCAAAAGTGGTTTGGAAGCTAAACACAGAAGGGCGATATGTCTGTGATATATGTGCAAAGACCTTTAAAACGGTACGATATTAAATCTTTTGGAAATAAGGAAAGGAAATAAGCACACAAAACTCACTTTGTCTGTAAAACTGATCTGTTTATAGACAAATATTCTGAGAACCCACATGTTCACGCACAGCGATCAGAAGAACTTTGTGTGTGAAATGTGCGAAACAGCGTTCAGGACCAAGGGCTCGTTAATCAGACACAAACGT[C/T]GACACACGGGTATGTCTAAGCTCTGTGAGACTGTGTCATTATACTGGACTGTCTACTGGGTAGGGATGGCTATTTGGTGTTTTTATTAAACATACAAAAACTGGCAGACTGTCACTATTGTGCCGATTTTCTTTGTTCATTATTTGTTTAATATGATAATGCAGCAGCTTTATTATGTACACACACTTTCAACCAATTGGGTTTTTATCAAGTTTGGTGTATTTCTTTGTCAGACGAGCGTCCGTACCGCTGCAATCAGTGTGGACTTGCGTTCAGAGAGTCTGGTGCTCTAACTAGGCATCTGAAGTCTCTCACGCCTTGTACTGAGAAGATTCGCTACAGTCAGTGTAAAGAAATACTTGTCAGCAAGGATGGGATTCGAAAAGGTAATTCACATCCCAACATGGCTTTCTTGAACAACCCTTATTGGGTATAAATATATTTTAGGTTTGTGCGATATTGACAAAAACACCCAAGTATATTAGTTGAGCGTGCTTTTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40033
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000055767 Essential Splice Site 528 719 11 14
Genomic Location (Zv9):
Chromosome 3 (position 18542211)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 18570573
GRCz11 3 18720313
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGGGGCTTCGCTGAGCATGGAACTCTGAACCGCCATCTGCGAGCTAAAGG[T/C]CTGTCAGTGTGAATTAATCGAATTATACTCGCATTCATTAAAGCACATCA
Long Flanking Sequence:
CCTTCAAAGGTTACAAGCCGTTTAAGTGTTTAACATGTCAGAAAGAGTTCCTGACAGGCTATGTGTTGAAGAAACACATGGAGACACACGTCAGTGAGCGCCGTTACAAATGTGGAGAGTGCGGCAAGCAGTTTAAAGCCATCGGACATGTGCGCGAACACATGAGAGCGCATTCAGACGAGAGGCCGTACCACTGCAGCTTCTGTGACAAGAGCTACAAGACCAAGGTGAGGTTAATATGCTGAAACTGTCCAAAGGTTTATATGTTATTATCTTAAAATCATTTCTGTCCTGTTTCAGAATGCTCTTCAAGTCCACCATCGCACTCATGCAGATGATAAGCCGTACGTGTGTCAACACTGCTCCCGTGGCTTCAGGGAAAAGAGCGCTTTAGTGCGTCACATCCGACATCATACTGGAGAAAAGCCATTCAAGTGCTCGAAATGTGGACGGGGCTTCGCTGAGCATGGAACTCTGAACCGCCATCTGCGAGCTAAAGG[T/C]CTGTCAGTGTGAATTAATCGAATTATACTCGCATTCATTAAAGCACATCAGTACTAAAAAGCATGTATTAGGCTGTCTGGCATATTAAGATTAAGGGTGTGCAAGAGTTTTGAATGTGAGTGCGTTTTAAAAGTTTTAAAGGGATTTATTGGTTGGCTCATATGTTCAAAGCCGACCCAATTACAATTTGAACAAGTAACTGTTTTTATTATCAGTACTTCCAGGGCTTTGTAAGTCCAATGGTTCTTTAGATTTGCTGTTTACAAGAATTGAAGCAGGGTGTCTGCGGGGTCTTAAAAATATTAAAAGTTAATAAATCAATGTAGAGAGATTTAGGGCTCTTAAATAGTAGTAAATCAAAGTCCCTTTAAGACAAGTCATTTCACTTGGCGGCAATTCTGTTTGAATGGGGAAACATCAAATTCTCTAAAACTACTTGCCAAGCTTACAATTACATTTTATATGATTAATAACCAATACAGTTAAACAACAACTGTCTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44561
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000055767 Essential Splice Site 603 719 13 14
Genomic Location (Zv9):
Chromosome 3 (position 18536651)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 18565013
GRCz11 3 18714753
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCAGCTCAAGGAGAAGAAGTGGCAATAATTCAAGACAATCAGCAGCAGG[T/C]GATTTCTCAAGTTTTCATTTTTATCATTGAAATTTCTATTGCACTTAAGC
Long Flanking Sequence:
TTTTTCTGCGATAAATATTGCGATATGAATAGTTTCACAAGATAGTTGAATAGCTCTGTTTGACGGTTTTCTGAGGAGTCTAACAGTATTCAGGTACAGAAATTCTTAGATCAAGAACTAGAAACAAAGGCCAATATTTAAAGTAATAAAAACTTTCGAAACTGTTCTATAAATCATATAAACTCCATACAAACACAGTGTTTAAAGACAATTCTGTAGCTCCAGGTCAACTATAATCCAGACTTAACATTGCATATCTTTGTGATGTGACTATTGCGGATGCGCACATTGGGATATTGATGCTGAAACGATATATTGTGCAACGCTAACAAATAAAATGGATTGCCAATAATAGCCAAATATTGATCTAAACATCAGAACACTTAGTTTTTGAAATGATTTGTTTATTTATGTATTTGTGGTCTATTTTTTGCAGGCTCCAGCTGAGGAAGCAGCTCAAGGAGAAGAAGTGGCAATAATTCAAGACAATCAGCAGCAGG[T/C]GATTTCTCAAGTTTTCATTTTTATCATTGAAATTTCTATTGCACTTAAGCTTAAATGTTTGCAAGCGTTTTGGCGTATAACCACATTGCACATGTGTCTCACGTCAGATGGACAGTCACATCATGAAAGTAGTGCAGCAGATCGTCAGCCAATCACATGGAGGCCACCAGATCATCGTTCGAAACGTCACCGCGGACGAAACTCCAGGCATCTCAGACTCTGGAGACACAATCACCATCGCCACACCAGAGAGCCTGACCGAACAGGTAGCGATGACACTCGCAAACGCCATTAGCGATGGCACTATCCTTACCACAACAACAGAGGATACCGATGAGACATCCCACACCACTGTTACCATGGTAACAGCCGAAAACGTTGAAACAATCGAGCAAGAAGAGCAGTACGTCATCGCTTCACCTGAAGAAGTGGAAATCCAAACTGTGGTTGTGGTCTGACATGCACATTTTAGTTATCTTATAAATTTTTATTTGTTGCAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33133
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000055767 Nonsense 656 719 14 14
Genomic Location (Zv9):
Chromosome 3 (position 18536387)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 18564749
GRCz11 3 18714489
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGACTCTGGAGACACAATCACCATCGCCACACCAGAGAGCCTGACCGAA[C/T]AGGTAGCGATGACACTCGCAAACGCCATTAGCGATGGCACTATCCTTACC
Long Flanking Sequence:
ATGTGACTATTGCGGATGCGCACATTGGGATATTGATGCTGAAACGATATATTGTGCAACGCTAACAAATAAAATGGATTGCCAATAATAGCCAAATATTGATCTAAACATCAGAACACTTAGTTTTTGAAATGATTTGTTTATTTATGTATTTGTGGTCTATTTTTTGCAGGCTCCAGCTGAGGAAGCAGCTCAAGGAGAAGAAGTGGCAATAATTCAAGACAATCAGCAGCAGGTGATTTCTCAAGTTTTCATTTTTATCATTGAAATTTCTATTGCACTTAAGCTTAAATGTTTGCAAGCGTTTTGGCGTATAACCACATTGCACATGTGTCTCACGTCAGATGGACAGTCACATCATGAAAGTAGTGCAGCAGATCGTCAGCCAATCACATGGAGGCCACCAGATCATCGTTCGAAACGTCACCGCGGACGAAACTCCAGGCATCTCAGACTCTGGAGACACAATCACCATCGCCACACCAGAGAGCCTGACCGAA[C/T]AGGTAGCGATGACACTCGCAAACGCCATTAGCGATGGCACTATCCTTACCACAACAACAGAGGATACCGATGAGACATCCCACACCACTGTTACCATGGTAACAGCCGAAAACGTTGAAACAATCGAGCAAGAAGAGCAGTACGTCATCGCTTCACCTGAAGAAGTGGAAATCCAAACTGTGGTTGTGGTCTGACATGCACATTTTAGTTATCTTATAAATTTTTATTTGTTGCATTGCAAGCCTTGGTGTAGCATTTCCGTTCTCTGGGAGGCCTTGTTTTACATGTTTTGCACTGCTCAATACAGTTACACATCATTTCAGTATTAAAAACTTTTTAACAGAAACGCTACTGAATTAATAGGGCGTAATGTCGTTTTTGTTTTAATTTCAGACATTAAACAATACGTTTCTTTTGTATGTTCAGCCTTTATAGCAGTGACGCTGACATATGAACATGTTGCTCCTGTTGAATGTCATATAATTATAAACGACTATCAT
Associated Phenotype:
Not determined