Busch Lab

ZMP

kcnh2

Ensembl ID:
ENSDARG00000029881
ZFIN ID:
ZDB-GENE-070912-699
Description:
microtubule-associated protein 4 [Source:RefSeq peptide;Acc:NP_001036187]
Human Orthologue:
KCNH2
Human Description:
potassium voltage-gated channel, subfamily H (eag-related), member 2 [Source:HGNC Symbol;Acc:6251]
Mouse Orthologue:
Kcnh2
Mouse Description:
potassium voltage-gated channel, subfamily H (eag-related), member 2 Gene [Source:MGI Symbol;Acc:MGI

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa31277 Essential Splice Site Available for shipment Available now
sa14572 Nonsense Available for shipment Available now
sa19755 Nonsense Available for shipment Available now
sa32915 Nonsense Available for shipment Available now
sa19754 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa31277
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000024058 Essential Splice Site 26 1253 1 15
Genomic Location (Zv9):
Chromosome 2 (position 23783019)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 24425476
GRCz11 2 24081127
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCTCAGAACACCTTTCTGGACACCATCATTCGCAAATTCGAGGGTCAAAG[T/A]AAGTGAATGACTTTTATTTTAGTGAACGTGCATTGATTATGTTTTTAAAA
Long Flanking Sequence:
CTCACTGCCTCTCCATATTCACTATCAATCTATGCAATTTTAGTCAATTTTATTTTTAAACGCTCCCAAACACAGAGAGGGGCTGTTTCGCAGCGCGTCGGAGAAAGTGATTGAGTGAACTGGGACAGAAAGTTGATTTGCATCCATTTGCAAACAAAAAGGGAAGCAGGTGACGTGAGGTAATTGGAGAGACGGCTGATTTACTGAGCTCGAGGATGCGCGCACTGACAGATTTAACACGTAATCACTGGAGACTTTGAAGAGACGCGCTCTCGTGCTGCTTTTACATCGATGTGGTGTGAAGGTAAAGCTTGTGTACATGTGTAACACTTCGCGGTAGAGTCGATATATCGCTCTTATTCAAGTAAATACAAGCTGTCGAGGAACTTGCAGAACTTTCTTGCCCTGCTGTGGTAGGACAACATGCCTGTACGACGGGGACACGTTGCGCCTCAGAACACCTTTCTGGACACCATCATTCGCAAATTCGAGGGTCAAAG[T/A]AAGTGAATGACTTTTATTTTAGTGAACGTGCATTGATTATGTTTTTAAAACAGTTTCTAATGCTGACTATTGTTATTATTAAATATTTTGTTATTAATATTATTTTATTATCAATTGCCATTGAAAATTACTAATTGTCACTAATAATAATGTCGTTAATAACTTAATTTGAGTTAAACGTGTCAGAACAGCTAAGTAATCATTTACTTTTGCTATCTGAATATGTAAAAATAGTTAATTAAACATAATTTTACTTTTATTATTATTTTTAAAGTAGCCTATGTAAAACTAATTGATTTCAGATTTTCAGTAAGCTGCTGTTTCAGTAGATCTTTTAATGTAGCTAAAGCAGACACATTTATTCTGAACTGCAGCTCAATTTTGATTCTGCATAGATGTGGTTAATAAAATTTTTGCATTTCTATTTTTCTTGTACCTCAACAGATCGCAAATTCATCATCGCCAATGCTCGAGTTGAAAACTGTGCCATCATCTTCTGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14572
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000024058 Nonsense 161 1253 4 15
Genomic Location (Zv9):
Chromosome 2 (position 23758856)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 24449639
GRCz11 2 24105290
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATCTARYACAATACATTTATTTCTTACCCTTGGGTATTTCCTCAGCAAGA[C/T]GACGTCGTCTCCGGCTGCCACTGCCCTTGCTGCACTCTCTGAGTGGCAGK
Long Flanking Sequence:
TGTTGCACATCAGGGAATTTATTTGATAAATGTTTTTTTCCATCATAGCTTTTAATATGTTTTCTTATGTAAACTGTATCAGTCCCAATCTAGAACATACGTTATTAATCACATTTTAGTATTTTATGATCATCTTGGTTTTTATGTATTATCTCAAAATATTTTTTATAATATGTTAATGCAAATGTAGTGCACAGTCAACAATTTTTGTAAATTATATAGTATTTAACATTAATATGAACTGTATTTTAATGTAGGACAGTTATGCGGTCTGTATTGTGAAAATTACCATATTACAATTTTGTAGATATACAGCAATAGCAATGGTGCTGTCAATGTAAATACAGTATTTTTGCTCTAATTGATTTACTGTAAGTTACTGGTGAACTGCTGCAAGTAAGTTACTGTAGATTCTACAGGAAATTGTTAACAGTGTAGTGTGTAATTATGATCTAACACAATACATTTATTTCTTACCCTTGGGTATTTCCTCAGCAAGA[C/T]GACGTCGTCTCCGGCTGCCACTGCCCTTGCTGCACTCTCTGAGTGGCAGTAAACAGTCTCTGCATGAAGACACTGAAAAAGGCTTCATGCAGCCGATGCCTCATATGGGCCATGAGTCAGTAGCCCTGGACAAACTGCTCTCCCTACCTGAACGCTCAGCACTCGGAGGATCTCAGCTGTTGTTCTGGGAAGATAAGGCTCAGACTGAGTCTGAAAGTGAGCTGCGGCCATCAGAAGTGTCTCCTCCTCTGCCTCAGGGCTTCTCGCAGTCCTCCCCACGTCTGCACAACCTCACCTCAGAGGCGTCTCCGTCCAGTTGCAGCATGGCCCACAGCCGCTCCTGTGAGAGCCTGTGTGGCATGAGGCCCTCACCCTCCACCAATGACTTTAACTGGGACAGAAAACTGCCAGTCAGACCCAGTAGCACAGGTAAAATAGAAGGTTGAATGCGCTGACCAGATTTCTGAAATGTATTATCGAATTTAGTGGTAAAAATAAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19755
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000024058 Nonsense 267 1253 4 15
Genomic Location (Zv9):
Chromosome 2 (position 23758536)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 24449959
GRCz11 2 24105610
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCCTCCCCACGTCTGCACAACCTCACCTCAGAGGCGTCTCCGTCCAGTTG[C/A]AGCATGGCCCACAGCCGCTCCTGTGAGAGCCTGTGTGGCATGAGGCCCTC
Long Flanking Sequence:
GCAATGGTGCTGTCAATGTAAATACAGTATTTTTGCTCTAATTGATTTACTGTAAGTTACTGGTGAACTGCTGCAAGTAAGTTACTGTAGATTCTACAGGAAATTGTTAACAGTGTAGTGTGTAATTATGATCTAACACAATACATTTATTTCTTACCCTTGGGTATTTCCTCAGCAAGACGACGTCGTCTCCGGCTGCCACTGCCCTTGCTGCACTCTCTGAGTGGCAGTAAACAGTCTCTGCATGAAGACACTGAAAAAGGCTTCATGCAGCCGATGCCTCATATGGGCCATGAGTCAGTAGCCCTGGACAAACTGCTCTCCCTACCTGAACGCTCAGCACTCGGAGGATCTCAGCTGTTGTTCTGGGAAGATAAGGCTCAGACTGAGTCTGAAAGTGAGCTGCGGCCATCAGAAGTGTCTCCTCCTCTGCCTCAGGGCTTCTCGCAGTCCTCCCCACGTCTGCACAACCTCACCTCAGAGGCGTCTCCGTCCAGTTG[C/A]AGCATGGCCCACAGCCGCTCCTGTGAGAGCCTGTGTGGCATGAGGCCCTCACCCTCCACCAATGACTTTAACTGGGACAGAAAACTGCCAGTCAGACCCAGTAGCACAGGTAAAATAGAAGGTTGAATGCGCTGACCAGATTTCTGAAATGTATTATCGAATTTAGTGGTAAAAATAAAATTGAAATCTCTCTTATGATTATATATTTAAAATTTGGGGACAGCACATTTAGTATAGTTCTTATTTTTAATGAAAATATCTCTGGTTGAGGATGAGAAAAGAATAACAGGGAAATCTGATTACTCAGTGGTAGAAGAAAAAAACAGGTACACCTGGTCATACAGTGGTCATACAGTCAAAAATGAGCCAAAAGATCATGTCACAAGTGACATGCAAAGCAAATGTCTTTTATTGTCTTTTAACACGGCCATTTATTAAGGTCTGTGTAGATTTGATCATCAATTTTTGTAATCAATATATTGGAATGCCTGAGAAACAGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32915
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000024058 Nonsense 598 1253 7 15
Genomic Location (Zv9):
Chromosome 2 (position 23706458)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 24502037
GRCz11 2 24157688
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTCGAATCGGTTGGCTTAATTCTTTGGGTGATCAGCTGGGAAAGCCATA[T/G]AATTCATCAGTACGTGGATCAGGACCCTCTATTAAAGATAAATATGTCAC
Long Flanking Sequence:
CAATACTTAAATCACTGTTAGTTCATAATAAAGTAAGATTTAGATTACATATTAATACATCATTATTCAAGTACCTTTATTGTTAAGTGTTATTGATAAATGGTTCACATTTTAGACCACATAGACTGCTATTGTGCCCACTCTGGAAACAGTTTTGAAAAAGTGATAAAAGAAATGCACCCTAGCAACTGTAATAACTGCTGCCGGTCAACTTACAACCTTTTAATTTTAAATTTTTTGATGTGTTAATAGACCACGACATCCACAACTCTGATTGGCCTGCTGAAAACAGCTCGGTTGCTGCGATTGGTGCGTGTGGCACGCAAACTTGACCGCTACTCTGAGTATGGAGCTGCTGTTCTCTTTCTGCTCATGTGTACCTTTGCTCTGATCGCCCATTGGCTGGCCTGCATCTGGTATGCGATTGGGAACGTGGAGAGAAGCGGCCCATCTCGAATCGGTTGGCTTAATTCTTTGGGTGATCAGCTGGGAAAGCCATA[T/G]AATTCATCAGTACGTGGATCAGGACCCTCTATTAAAGATAAATATGTCACTGCCCTGTACTTCACCTTCAGCAGCCTCACCAGCGTGGGCTTTGGAAACGTCTCCCCAAACACAAACTCAGAGAAGATCTTCTCCATCTGTGTGATGCTCATCGGAGGTTAGTGCTGCTAAGTGCTTATTCATATTCTAGAATGATGTCAGTGAGATTGTACAGTTATCAGTTGAACAATAATATTATAAAATACTTTCAGAACAAAGAATAGCTGTTTCTATATTAATACATTGAAGTTATTCATATACATTATAGTCTGACATTCAGTTTCACAGACACGATCCTTCAAAAATATTCTAATAGGCTGATTTAGAGCTCAACATTTAAATGTTGTGCTGTGTTAACTATTTTTAAGTAAATTGAATGACTAGAATGCTCAGAAGAACAGCATTAATTTTAAATTACATTATTATTATATATAATTTAGTGTATCCTTGTTGAAAAAGTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19754
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000024058 Nonsense 1229 1253 15 15
Genomic Location (Zv9):
Chromosome 2 (position 23695967)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 24512528
GRCz11 2 24168179
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACAAGCTGTACAGAGTTTACATTTGGAGACCTCTGAGTGTTCAAGACGC[C/T]AATCGCTGCCAGTAAAACATCAGGTCGAAGATGATTGCTCAATGCAGAAA
Long Flanking Sequence:
ACACAGGACAATGTCCATGTCACTATTTTATTAAATAGCCTATTTTTTCAGATTTGAACATTCTTCAAAATAATAGAAATACATAAGTCGGGAAATTTTAATGAACATATTATACATTGTGCATTGAAGTTAACTCTACTTAATTTTGTGAACACACCATCTTTGATTTTTTTTTCTAGATACTTGATCCTCATGACTTTGCTGACAGTCCTATTAAGGCCAGTGAAAGTCTGTCAGGTGCAATGGAGCTCCAGCTCCTGGACTGTTCCTCACAGCCTCCCTCTGAGAATCCTTCTGGGGCTTATATGGGGAGATGGTCACGTAGCGTAAGCCACCACACAAACACCACTGGTGATCCTACAGCACACATCCATCTCCAACAAACAGCCATAGCTGATCAAGCTCATTACAGCTTTTTGGATGCAGAGCCTATTGGAACTCTTCGCCAACCACAAGCTGTACAGAGTTTACATTTGGAGACCTCTGAGTGTTCAAGACGC[C/T]AATCGCTGCCAGTAAAACATCAGGTCGAAGATGATTGCTCAATGCAGAAAAGACATCCCTCTGATCCTGGCTCTTAAGACAAACTTGTTCGGTATCTCAGTGGAAAACAATGCAAAGACCACCAACATGTTGGCATGGTGTTTAAAAGACTATTCAGGATCATATATAATTACCTCAGAAAAACGGTCAAGGATGCATCATTATTGTCCCTGTAGGTTTGTACATTTGTGTTAGCTGGTTTAACAATATTCATTGTTTTTACCTGCCTCATTATGAAAGTGTTCTCATTGTTTTGAGGTGTAAATGTAATGATTTGTATTAGCATATCAGCTTTTTTTTTACAATGTGGTTTTGTGTTGAATTGATTAGCCTATACTGTAGATTTTTTTTTAATAACTGAAACACTGGAAAGGCCAATCAGAGCAGGATTTATTAGAGTTCAAATGATCATTTGGAAACTTTAGCCCCTTTCATACATACAGACTTTTTCAGAAAATTGT
Associated Phenotype:
Not determined