Busch Lab

ZMP

gpt2l

Ensembl ID:
ENSDARG00000019541
ZFIN ID:
ZDB-GENE-050302-11
Description:
Alanine aminotransferase 2-like [Source:UniProtKB/Swiss-Prot;Acc:Q6NYL5]
Human Orthologue:
GPT
Human Description:
glutamic-pyruvate transaminase (alanine aminotransferase) [Source:HGNC Symbol;Acc:4552]
Mouse Orthologue:
Gpt
Mouse Description:
glutamic pyruvic transaminase, soluble Gene [Source:MGI Symbol;Acc:MGI:95802]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa14498 Nonsense Available for shipment Available now
sa38309 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa2059 Nonsense F2 line generated Not yet available
sa5713 Nonsense F2 line generated Not yet available
sa32832 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa14498
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000005667 None None 566 None 12
ENSDART00000132572 None None 562 None 12
ENSDART00000133007 Nonsense 25 193 1 4

The following transcripts of ENSDARG00000019541 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 4027985)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 3702511
GRCz11 2 3533690
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GGGYTTTWAAATGGGGGAGWTGTGAGGCGGCTTAYGCGGCGGCGTACCCC[A/T]AGGTTCCTGACTGGGTTCTCAACTTTYCCCCGCTGCCTTCCCTTTCTTCT
Long Flanking Sequence:
CAAAGTTTGGAGAGCCGCTTTCAGACGCTTCACACGCGGATTTATCGCTTCTGTCTGTGGTCTCGGCAACCGAGGAGGCTCCTTTACTACACTTCTGGTGCGTAATACAGTCAGGAGGAGGCACTGACCATAAAACTCCCCGTTTTAAAAGGGGGCCAGTCATGGAAAAGTAAATAGGGGGGACACATATCCTGTTTGTGAGGCCAGTAGATAAAAAAAGAGGCGTGGGGTTTTTAGCGGGGCTACTTATGAAATCTTGAATAATCTGATGTACAGTCCAAAGGTCTCCCAGAGTGGATCTTGGAAGGTTGAACTGCGCGCGTTACGACAAAACGTGCGCAGAAATAACCAAAGATTAAATACGCAAAATTTCAGTTTTTACCTCATATGCTTTTTGTAAACGTTTTTTATAGCCATAACTCTTTAAAATGTTGTCTAAGAGAAGCTTGAGGGTTTTAAAATGGGGGAGATGTGAGGCGGCTTACGCGGCGGCGTACCCC[A/T]AGGTTCCTGACTGGGTTCTCAACTTTTCCCCGCTGCCTTCCCTTTCTTCTCCCCATAGGGATTTTTCTGCTTTCCCGGCGGCCCAAAGCGAGCATATGCAGCAGAAGATGTCTGAAAATGGAGCGATACCCCGGCAGGGGAAAGTGCTGACTGTTGACACCATGAACGCGAACGTGAAGAAAGTGGACTACGCGGTGCGGGGACCAATCGTCCAGCGAGCCGTGCAGATCGAGAAGGAACTCAAAGAGGTACGAGCAGAGCTCAGTTCGCCTCAGCAAAGTAATGTTTATGCAATAAATTCTGCAAACATCCTTTTGGAAGCAAGATATCCACTAGGATAACAGGATAATGATGTGTTTATTTGACTTTCACCCCCACCTTTGCTTAACAAACTTGGTGAACTGATGCTCATCTGGGCTGCTGTTATACTGCTTGACTCTATAACTGCTTGCAGATTTTTATGCTTATATACAGTTGAAGTCAGAATTATTCACCCCCCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa38309
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000005667 Essential Splice Site 154 566 3 12
ENSDART00000132572 Essential Splice Site 150 562 3 12
ENSDART00000133007 Essential Splice Site 137 193 2 4

The following transcripts of ENSDARG00000019541 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 4051427)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 3725953
GRCz11 2 3557132
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGGAGACGCTCACGCTATGGGACAACGGCCAATCACCTTCTTCCGACAGG[T/C]AGCAGATTTCTCTATTCTTTGCTGACCGCGTCATTTTCCTAGTCACTTTC
Long Flanking Sequence:
CTATCAAGTCAATATGGAGCAAAATCTCTGAGGAATACTTCTAGTACCTTGTTGAATCTATGCCAGAAAGGATTAAGGCAGATCTGAAAGCAAAAATGGGTCCAACCTGGTACTAGTAAGGTGTACCTAATAAAGTGTAAAATCACCAAGAATCACGGATTCAGCTTAAAATCTTCTTTAATGTACTTCTTCTACCTAATGTTGACCTGTGGTTGCGTAAATGAGCAGGGAATTTTCATTTTTGGGTGAACTATCCCTTTAAGGTTTACATTAAACACTTTTAGCCTGGTTTATATTGGATCACCCAGAAACGTAATCTTCCTGGCATTACCCCAAACTGCCAAATTTCCTGTGCTCTATATGAAGTACAATCCATATAGATCACAGCATGTGTTTTACTTCTTTACAGGGGGTCAAGAAGCCCTTCGATGAGGTCATTAAAGCAAATATCGGAGACGCTCACGCTATGGGACAACGGCCAATCACCTTCTTCCGACAGG[T/C]AGCAGATTTCTCTATTCTTTGCTGACCGCGTCATTTTCCTAGTCACTTTCAGGCCGGCTGCGCTTTCCATGCATTAAACAGAGTCAACAGTTTAAGTGGAGCAGCCTGACACATCTTCATGCTCTTTAACTTTATTAATGCTTACTTTGTTGTTCTCGCACGCTCATAATTGGTTTGTTTTTCAAGGTGATGGCGCTGTGTACTTATCCACAGCTACTTGATGACAACAAGTTTCCAGAGGATGCCAAAAACAGAGCCAGGCGTATTTTGCAATCGTGTGGAGGGAATAGCATCGGTATGTTATTGATGCATGAAGGGAATTGACATGAAATATGAAGTATCAACAATCGCGCAAGCTAAAATAATAAAGGGAAATTGCGTCATTGGTATATTTGCAGTTTTATAACCTCATGGTTTAGGGGTGACGCAGTGGCGCAGTAGGTAGTGCTGTCGCCTCACAGCAAGAATGTCGCATGGTCGCTGGTTCAAACCTCGGCTCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2059
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000005667 Nonsense 467 566 10 12
ENSDART00000132572 Nonsense 463 562 10 12
ENSDART00000133007 None None 193 None 4
ENSDART00000005667 Nonsense 467 566 10 12
ENSDART00000132572 Nonsense 463 562 10 12
ENSDART00000133007 None None 193 None 4

The following transcripts of ENSDARG00000019541 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 4062144)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 3736670
GRCz11 2 3567849
KASP Assay ID:
554-3150.1 (used for ordering genotyping assays)
KASP Sequence:
GGCYGTTCTCAGTGCCTTGGCTGAAAAAGCCAAACTGACGGAGCAGATTT[T/A]GAACACAGTGCCAGGCATCAGCTGTAACCCAGTGCAGGGAGCCATGTACT
Long Flanking Sequence:
CCACAGACTTTTTGCTGGCTGTATGTGGGCAGAGTAATACACAAAGGGTAAAGAGGCTGTACAGGTGCTGATATTACTTAAATATATCACGGCTATCAGCCAATGAGATTCGAGAACCAGACAGAACTGTTGTATATTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATACACACTTTTTATAATATAATGATAATAATAATCATTATTTTTGAGTCCTTGTTACGGAGATTGGTTGTAGGAAAGTGTCTGGTGCATAGAGCATAGAGAGTGTCTGGTGCATATGGAGAGGTCTTCTACAGGTGGTTTGTCAAACTTTACCATTGTAGAGTGTTTCTTCAGTTTCTGCTGAAAAGGATGTCTGTTTCTCCCAGTCTTCTCCACTGATTCAGTGCTCTTCCTCTGTTCTGGCAGGAGCGGACGGCTGTTCTCAGTGCCTTGGCTGAAAAAGCCAAACTGACGGAGCAGATTT[T/A]GAACACAGTGCCAGGCATCAGCTGTAACCCAGTGCAGGGAGCCATGTACTCTTTCCCCCGAATCACCCTGCCTGAGCGCGCCATCAGCGAAGCCAAGGTCGGTGTCTGGCACATGCTCTTTATGCCTGCTGCTGGTGTTATTTACTTGACTTAATCATCGGCCGTGTGTGTGTGAATACAGGCGAAGGGTCAGGCTCCAGACATGTTCTACTGCATGAAACTGCTGGAAGAGACCGGCATCTGTCTCGTTCCTGGAAGTGGTTTCGGTCAACGGGAAGGCACTTATCACTTCAGGTAAGAGTGTGTGTTCTCAAGTGTTTTCCCTCTTATTGTTTGAGAGAGGTTCCCTCTCAGGGTTTGTGCGGGGAATTGCTGACACACAATATATTGTAAACCAGAGTGAAAAAGAAAAAAAAGGGGGGAGGGGGGGGGGTGCTAGGTGTCACAGATAAAAGTGAAGAGGGTTGGGGAGTCATGGAAGAAAGTGAAAGTAAAGAGTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa5713
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000005667 Nonsense 467 566 10 12
ENSDART00000132572 Nonsense 463 562 10 12
ENSDART00000133007 None None 193 None 4
ENSDART00000005667 Nonsense 467 566 10 12
ENSDART00000132572 Nonsense 463 562 10 12
ENSDART00000133007 None None 193 None 4

The following transcripts of ENSDARG00000019541 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 4062144)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 3736670
GRCz11 2 3567849
KASP Assay ID:
554-3150.1 (used for ordering genotyping assays)
KASP Sequence:
GGCYGTTCTCAGTGCCTTGGCTGAAAAAGCCAAACTGACGGAGCAGATTT[T/A]GAACACAGTGCCAGGCATCAGCTGTAACCCAGTGCAGGGAGCCATGTACT
Long Flanking Sequence:
CCACAGACTTTTTGCTGGCTGTATGTGGGCAGAGTAATACACAAAGGGTAAAGAGGCTGTACAGGTGCTGATATTACTTAAATATATCACGGCTATCAGCCAATGAGATTCGAGAACCAGACAGAACTGTTGTATATTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATACACACTTTTTATAATATAATGATAATAATAATCATTATTTTTGAGTCCTTGTTACGGAGATTGGTTGTAGGAAAGTGTCTGGTGCATAGAGCATAGAGAGTGTCTGGTGCATATGGAGAGGTCTTCTACAGGTGGTTTGTCAAACTTTACCATTGTAGAGTGTTTCTTCAGTTTCTGCTGAAAAGGATGTCTGTTTCTCCCAGTCTTCTCCACTGATTCAGTGCTCTTCCTCTGTTCTGGCAGGAGCGGACGGCTGTTCTCAGTGCCTTGGCTGAAAAAGCCAAACTGACGGAGCAGATTT[T/A]GAACACAGTGCCAGGCATCAGCTGTAACCCAGTGCAGGGAGCCATGTACTCTTTCCCCCGAATCACCCTGCCTGAGCGCGCCATCAGCGAAGCCAAGGTCGGTGTCTGGCACATGCTCTTTATGCCTGCTGCTGGTGTTATTTACTTGACTTAATCATCGGCCGTGTGTGTGTGAATACAGGCGAAGGGTCAGGCTCCAGACATGTTCTACTGCATGAAACTGCTGGAAGAGACCGGCATCTGTCTCGTTCCTGGAAGTGGTTTCGGTCAACGGGAAGGCACTTATCACTTCAGGTAAGAGTGTGTGTTCTCAAGTGTTTTCCCTCTTATTGTTTGAGAGAGGTTCCCTCTCAGGGTTTGTGCGGGGAATTGCTGACACACAATATATTGTAAACCAGAGTGAAAAAGAAAAAAAAGGGGGGAGGGGGGGGGGTGCTAGGTGTCACAGATAAAAGTGAAGAGGGTTGGGGAGTCATGGAAGAAAGTGAAAGTAAAGAGTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32832
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000005667 Nonsense 492 566 10 12
ENSDART00000132572 Nonsense 488 562 10 12
ENSDART00000133007 None None 193 None 4

The following transcripts of ENSDARG00000019541 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 4062218)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 3736744
GRCz11 2 3567923
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTAACCCAGTGCAGGGAGCCATGTACTCTTTCCCCCGAATCACCCTGCCT[G/T]AGCGCGCCATCAGCGAAGCCAAGGTCGGTGTCTGGCACATGCTCTTTATG
Long Flanking Sequence:
TACTTAAATATATCACGGCTATCAGCCAATGAGATTCGAGAACCAGACAGAACTGTTGTATATTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATACACACTTTTTATAATATAATGATAATAATAATCATTATTTTTGAGTCCTTGTTACGGAGATTGGTTGTAGGAAAGTGTCTGGTGCATAGAGCATAGAGAGTGTCTGGTGCATATGGAGAGGTCTTCTACAGGTGGTTTGTCAAACTTTACCATTGTAGAGTGTTTCTTCAGTTTCTGCTGAAAAGGATGTCTGTTTCTCCCAGTCTTCTCCACTGATTCAGTGCTCTTCCTCTGTTCTGGCAGGAGCGGACGGCTGTTCTCAGTGCCTTGGCTGAAAAAGCCAAACTGACGGAGCAGATTTTGAACACAGTGCCAGGCATCAGCTGTAACCCAGTGCAGGGAGCCATGTACTCTTTCCCCCGAATCACCCTGCCT[G/T]AGCGCGCCATCAGCGAAGCCAAGGTCGGTGTCTGGCACATGCTCTTTATGCCTGCTGCTGGTGTTATTTACTTGACTTAATCATCGGCCGTGTGTGTGTGAATACAGGCGAAGGGTCAGGCTCCAGACATGTTCTACTGCATGAAACTGCTGGAAGAGACCGGCATCTGTCTCGTTCCTGGAAGTGGTTTCGGTCAACGGGAAGGCACTTATCACTTCAGGTAAGAGTGTGTGTTCTCAAGTGTTTTCCCTCTTATTGTTTGAGAGAGGTTCCCTCTCAGGGTTTGTGCGGGGAATTGCTGACACACAATATATTGTAAACCAGAGTGAAAAAGAAAAAAAAGGGGGGAGGGGGGGGGGTGCTAGGTGTCACAGATAAAAGTGAAGAGGGTTGGGGAGTCATGGAAGAAAGTGAAAGTAAAGAGTGGACGGGGGAGGAGGGCGATCGGTAAAATAAGGTGCTGGATCAGGTTTCAGAGGTGCTGGATTCCGCGTGTTCCC
Associated Phenotype:
Not determined