Busch Lab

ZMP

zgc:64115

Ensembl ID:
ENSDARG00000036588
ZFIN ID:
ZDB-GENE-040426-2149
Description:
major histocompatibility complex class I ZE like [Source:RefSeq peptide;Acc:NP_001103588]
Human Orthologues:
AL645933.1, AZGP1, FCGRT, HFE, MICB, MR1
Human Descriptions:
Fc fragment of IgG, receptor, transporter, alpha [Source:HGNC Symbol;Acc:3621]
MHC class I polypeptide-related sequence A isoform 2 (MICA*00801) precursor [Source:RefSeq peptide;
MHC class I polypeptide-related sequence B [Source:HGNC Symbol;Acc:7091]
alpha-2-glycoprotein 1, zinc-binding [Source:HGNC Symbol;Acc:910]
hemochromatosis [Source:HGNC Symbol;Acc:4886]
major histocompatibility complex, class I-related [Source:HGNC Symbol;Acc:4975]
Mouse Orthologues:
Azgp1, CR974466.3, Fcgrt, Gm11127, Gm7030, Gm8815, Gm8909, H2-Bl, H2-D1, H2-K1, H2-K2, H2-M2, H2-M3, H2-Q10, H2-Q2, H2-Q6, H2-Q7, H2-Q8, H2-T10, H2-T22, H2-T23, H2-T3, H2-gs10, Hfe, Mill1, Mill2, Mr1
Mouse Descriptions:
Fc receptor, IgG, alpha chain transporter Gene [Source:MGI Symbol;Acc:MGI:103017]
MHC I like leukocyte 1 Gene [Source:MGI Symbol;Acc:MGI:2179988]
MHC I like leukocyte 2 Gene [Source:MGI Symbol;Acc:MGI:2179989]
MHC class I like protein GS10 Gene [Source:MGI Symbol;Acc:MGI:3808875]
alpha-2-glycoprotein 1, zinc Gene [Source:MGI Symbol;Acc:MGI:103163]
hemochromatosis Gene [Source:MGI Symbol;Acc:MGI:109191]
histocompatibility 2, D region locus 1 Gene [Source:MGI Symbol;Acc:MGI:95896]
histocompatibility 2, K region locus 2 Pseudogene [Source:MGI Symbol;Acc:MGI:95906]
histocompatibility 2, K1, K region Gene [Source:MGI Symbol;Acc:MGI:95904]
histocompatibility 2, M region locus 2 Gene [Source:MGI Symbol;Acc:MGI:95914]
histocompatibility 2, M region locus 3 Gene [Source:MGI Symbol;Acc:MGI:95915]
histocompatibility 2, Q region locus 10 Gene [Source:MGI Symbol;Acc:MGI:95929]
histocompatibility 2, Q region locus 2 [Source:RefSeq peptide;Acc:NP_034522]
histocompatibility 2, Q region locus 2 Gene [Source:MGI Symbol;Acc:MGI:95931]
histocompatibility 2, Q region locus 6 Gene [Source:MGI Symbol;Acc:MGI:95935]
histocompatibility 2, Q region locus 7 Gene [Source:MGI Symbol;Acc:MGI:95936]
histocompatibility 2, Q region locus 8 Gene [Source:MGI Symbol;Acc:MGI:95937]
histocompatibility 2, T region locus 10 Gene [Source:MGI Symbol;Acc:MGI:95942]
histocompatibility 2, T region locus 22 Gene [Source:MGI Symbol;Acc:MGI:95956]
histocompatibility 2, T region locus 23 Gene [Source:MGI Symbol;Acc:MGI:95957]
histocompatibility 2, T region locus 3 Gene [Source:MGI Symbol;Acc:MGI:95959]
histocompatibility 2, blastocyst Gene [Source:MGI Symbol;Acc:MGI:892004]
major histocompatibility complex, class I-related Gene [Source:MGI Symbol;Acc:MGI:1195463]
predicted gene 11127 Gene [Source:MGI Symbol;Acc:MGI:3779381]
predicted gene 7030 Pseudogene [Source:MGI Symbol;Acc:MGI:3647514]
predicted gene 8815 Pseudogene [Source:MGI Symbol;Acc:MGI:3648635]
predicted gene 8909 Gene [Source:MGI Symbol;Acc:MGI:3704134]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa32754 Nonsense Available for shipment Available now
sa16226 Essential Splice Site Available for shipment Available now
sa19563 Nonsense Available for shipment Available now
sa32753 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa32754
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000053153 Nonsense 69 398 2 9
Genomic Location (Zv9):
Chromosome 1 (position 47657852)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 46469513
GRCz11 1 47160745
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATGACAGACAGATTGACTATTACAATAGCGAACAGCAGAAGAAGATTCCC[A/T]AACAGCACTGGATGAAAGAGAAAATGCAGGAAGATTACTGGGAAAAAGGC
Long Flanking Sequence:
ATGAACCACATAAATTAGTGTTGTTCCAAATATCAACAATCAACAAGATTTCAAGTGATATTCACTAAACTTCAATAATATTTGTGTTTAATAAAAATGTGAAAGGCAGCATCATAGACTAAACTGACCTCAGCTGTGCCAAATATAAGAGCAATGATTAACTGCTACAGATGTTGCAATAGTTGGTCTATAGGTTGAAAGAAAAGGACAAAAACATCTTAAAACAATCTAACCAGATTTGTTTGTGATGGTCAGATGTCACCACTTCACCATGAAACTATTTTCATAATGTATACTTAAAAATGACCATGTGGATCATGTGTTTTTGACATTTTCATGTTTTGTTCTCTTTGAATACAGAAAAACACTCCCTCTACTACATATACACAGCTTTATCCAGACCTGTCAATCTGCCGGGCATCTATGAATTCACTGCAATGGGTTTGCTAGATGACAGACAGATTGACTATTACAATAGCGAACAGCAGAAGAAGATTCCC[A/T]AACAGCACTGGATGAAAGAGAAAATGCAGGAAGATTACTGGGAAAAAGGCACCCAGTCCAGAAAGAGCAAAGAACAGTGGTTTAATGTGAACGTCAACATTCTGATGGAACGAATGAGACACAATAAATCAGGTGAGGAATGGTTATCTGTTTTACCCTGCATATACACTACTGGTCAAAAGCTGTTCTATAAAAAATATTTTTAATGCTTTCTAAAACTGTCTGTTCTATTCACCAAGCCTGCATTTATTTAATGGAAAGTACAGAAAAGTATCTAAAAAATTAAAAAATATATGTATTTTTAGATAAAAGATAAAAATAATAATAATAATAAATTTTCCCAGTGATGGGCTGCAGCTGGAAGGACATCTCCTCCGCTGCTTAAAATATATGCTGTATAAGTTGATAATAAAATTAACAAAGGGACTAAGCCAAAAAGAAAATTAATGAAATAGTAATAATAAATAAGATAACAATTATTTGAATATATTTAAAAAGGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16226
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000053153 Essential Splice Site 209 398 4 9
Genomic Location (Zv9):
Chromosome 1 (position 47656386)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 46468047
GRCz11 1 47159279
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTGGTTAGTGTTATAKAACTGACTGATTAAACAATRTACTTGTGATTTC[A/G]GCTTCCCCAGAAGTTCATGTGTTWGCGAAGAGGATTATCARTGGCAAAAT
Long Flanking Sequence:
TTTTGCTGTACTTAGGTTCAAATAAAGTCAGGCTCAAAACAGTAAAACTTATCTATCCTATCTTATTTTTCATTAAAATATTACATCTGTATCATTTTTGCTTTTGATCTGTCTCATAGTCAGTTTAATTTGTGTCTGTTTCAGATGTTCATGTTCTTCAGTGGAGACATGGTTGTGAAATTGAGAGTCAGGGCAATGATGTCCGGTTTTCCAGAGGCATTGATGAGTACAGCTATGATGGAAGAAACTTCCTTTCTTTTGATGATGCGGAGTCTCAGTGGGTTGCCCCAGTGGAAGAAGCTCTTCCAACCAAGAGGAAATGGGATAATGTGCCCATCCTAAATCAGTACACCAAGGGCTACCTGGAAAAAGAGTGTGTGGACTGGCTCAACAAATTCAGAGAATATGGAGATAAGGAGCTTAGAGAAGGCTGTGAGTAAACATACAGCATTTGGTTAGTGTTATAGAACTGACTGATTAAACAATGTACTTGTGATTTC[A/G]GCTTCCCCAGAAGTTCATGTGTTTGCGAAGAGGATTATCAATGGCAAAATCAAGCTAAAACTTACTTGTCTGGCCACTGGATTCTACCCCAAAGATGTGATTTTGAACATAAGGAAATACCGCATTACACTGCCTGATAATGAGGTAGAATCCACAGGAGTTAGACCAAACGAAGATGGGACCTTTCAGCTGAGAAAGAGCATTAACATCTATGAGGATGAAAAAGCAGAATATGACTGTTATGTGTCCCACACAACCCTCAAGGAACCAATTATCAAAAAATGGGGTAATGAAACATACAGAAAAAGCACCTTATATTCAAAAAGCATCACAAAAGCTGTGAACCTCCATTTTTTGCCAAAACTATTTGTTTCTTTTTTTTTTAGTTTGATTAAAATTGTAAATACATATCTTTGTATTTGTGTAGATGGGGAGTGCCTGGATGGCCCTGAGTCAGGATCTCCCATAGGTATTATTGCTGGAGCAATAATTGTAGTTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19563
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000053153 Nonsense 247 398 4 9
Genomic Location (Zv9):
Chromosome 1 (position 47656271)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 46467932
GRCz11 1 47159164
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTGTCTGGCCACTGGATTCTACCCCAAAGATGTGATTTTGAACATAAGG[A/T]AATACCGCATTACACTGCCTGATAATGAGGTAGAATCCACAGGAGTTAGA
Long Flanking Sequence:
ATAGTCAGTTTAATTTGTGTCTGTTTCAGATGTTCATGTTCTTCAGTGGAGACATGGTTGTGAAATTGAGAGTCAGGGCAATGATGTCCGGTTTTCCAGAGGCATTGATGAGTACAGCTATGATGGAAGAAACTTCCTTTCTTTTGATGATGCGGAGTCTCAGTGGGTTGCCCCAGTGGAAGAAGCTCTTCCAACCAAGAGGAAATGGGATAATGTGCCCATCCTAAATCAGTACACCAAGGGCTACCTGGAAAAAGAGTGTGTGGACTGGCTCAACAAATTCAGAGAATATGGAGATAAGGAGCTTAGAGAAGGCTGTGAGTAAACATACAGCATTTGGTTAGTGTTATAGAACTGACTGATTAAACAATGTACTTGTGATTTCAGCTTCCCCAGAAGTTCATGTGTTTGCGAAGAGGATTATCAATGGCAAAATCAAGCTAAAACTTACTTGTCTGGCCACTGGATTCTACCCCAAAGATGTGATTTTGAACATAAGG[A/T]AATACCGCATTACACTGCCTGATAATGAGGTAGAATCCACAGGAGTTAGACCAAACGAAGATGGGACCTTTCAGCTGAGAAAGAGCATTAACATCTATGAGGATGAAAAAGCAGAATATGACTGTTATGTGTCCCACACAACCCTCAAGGAACCAATTATCAAAAAATGGGGTAATGAAACATACAGAAAAAGCACCTTATATTCAAAAAGCATCACAAAAGCTGTGAACCTCCATTTTTTGCCAAAACTATTTGTTTCTTTTTTTTTTAGTTTGATTAAAATTGTAAATACATATCTTTGTATTTGTGTAGATGGGGAGTGCCTGGATGGCCCTGAGTCAGGATCTCCCATAGGTATTATTGCTGGAGCAATAATTGTAGTTTTGGTTGTGCTGGCAGCCATTGGTGGAGCAGTTTATTTCCTAAGAAAGAGGAGCGGTGCGTATAGACTGATAAATGATCATTAACAATTTCATGTTTTTTAATTTTTTACAATATTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32753
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000053153 Essential Splice Site 398 398 8 9
Genomic Location (Zv9):
Chromosome 1 (position 47654679)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 46466340
GRCz11 1 47157572
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGTTCAAAAAGCAGTCCTACTAACTCACAGGAAAAAATGGACATTGTGG[T/A]AACTATGATTTACATGCAATATTAGTAAAGCCAGAGGGTCCACTGTATAG
Long Flanking Sequence:
AAAAATTAGACTGCTTTTTCATGCACTTATATTTTTTCATTATTGTAAGTTAAAATTAATATTAAATCAAAGTGCAGTATAAGTGAAATGTCTTGAAAAGAGTAGCAATACAACATTTACCCGTGATTGACTTTTATTACTTGATTGTGGGACTTGAATATCTGCATGTTGCAGGAAACAAGGATGAGAAATGCTCTATGCTACCTGGTTCAGACGACTCTGGTAAATATTCTTTTTATTCAGTTATTGATTGGCACATGCTTTCTTCTATTACAGAACTAAAATCAAATTGCTTTATTAAATGCATCTTGCTGTACTGCAAGATTCCACTTTCTTTCCTTTTTTATTTCTTTTGCTAGACAAAGTTTTGGCACACTGTTTTAAAAAAAAACATGCACAGCTCACTTTGACATTTCACTTTACATCAACAGGTCAAGGGAGTAGTGATGGAAGTTCAAAAAGCAGTCCTACTAACTCACAGGAAAAAATGGACATTGTGG[T/A]AACTATGATTTACATGCAATATTAGTAAAGCCAGAGGGTCCACTGTATAGAACTCTTCTGTTTGTAGATACTAGAGGAAAGGTTAAAAAAAAGTATTAAAAGAGGCACATTTGTTCAGATGGTTTTAGTAGTTTTACGTAAAGTTTTAGTTTTACATTTACATAAAGAAGGTGAGAAATAATTATTATACCAGAGCTCCCAGTTATTTTAGCTCTCTACAAATGTGCCTTAATCTTAGTAATCATAATGGGTCATTATTTTGTATTAAGTACATTTTTGATAAAAAAAAAAATCTCAAAGTGCTTTAAAAAGGTGAAATGAGCATCTCCGAAAGGAAAAATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTGTATATA
Associated Phenotype:
Not determined