ZMP
si:ch211-254d18.3
Ensembl ID:
ZFIN ID:
Description:
Novel protein (Im:6912504) [Source:UniProtKB/TrEMBL;Acc:B8A661]
Human Orthologue:
EIF5B
Human Description:
eukaryotic translation initiation factor 5B [Source:HGNC Symbol;Acc:30793]
Mouse Orthologue:
Eif5b
Mouse Description:
eukaryotic translation initiation factor 5B Gene [Source:MGI Symbol;Acc:MGI:2441772]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa38289 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa32742 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa32743 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa38289
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000074689 | Essential Splice Site | 106 | 1231 | 3 | 25 |
| ENSDART00000144245 | Essential Splice Site | 103 | 313 | 3 | 4 |
Genomic Location (Zv9):
Chromosome 1 (position 46404085)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 45241597 |
| GRCz11 | 1 | 45933392 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGGAGCTAACATTAGAAAACCAAGGAGGAAAGGTTAAAGAAGCAGAAAAG[G/A]TATTGTAATTTTTTGTGTGAGAGATTATCAAGTTTATCCCTTTGCAAAAA
Long Flanking Sequence:
TGCGATCAGGCTACTTTTCTACCTTTCTATTTTATGTAATATATAATGCAGCTTATTTTGGTGACCATCACTTGAGTTTAAATGTCAATAATCATTATCACTGTTGAAAAGGCTTGTGCTGCTTATTCTTTCTGAAATGTTTGGTATACAGAGTACAAAAAAAATATTTATTTGAACCCAAAATCTTTTGTACCTCTGTATTTAGTTAATATATCTTTTATTTTAGGATATATTATCCTGAAATAATTTACATTTAATTTATTAAATAATAAATAAATAATTTAATTTATAATTTTAGCCTTATTTAATATTTTCTTGCTAAAAAAAACATTAATAATTGTATTTTTTGTAAATAAAATTCGATTGATTGTAAATGGTTAAAAAGTAGTGTACAATTACTGATGAACTCTTTTTTTTCTTGCAGTGAGGATGACATCCAGAAAGAACTGGAGGAGCTAACATTAGAAAACCAAGGAGGAAAGGTTAAAGAAGCAGAAAAG[G/A]TATTGTAATTTTTTGTGTGAGAGATTATCAAGTTTATCCCTTTGCAAAAACAAGTCTTGAGTATCCAAAAGCATTGTGTGTGATGAGGCTTGTCAGGGTGTGCTCACACTAGGTACAGTTGCCTTGAACCGTGCCAAAGTGTGCTCGTCCCCCCTCCACTCTCCCCCAACAGCCTGCACTCACACTGCCTTTTTTACCTTCCGAGCTGGAGCACGCTTGCGTCATCGATTATGCGACTGGTCAGCTTCAACAGAAAGAGAAGCGCTCTTGCTTAGCACAGTGGACATTGCTTTAGTTATATCGTTTTGTATCAGTTTGGGATGCAGTGACGCGCAGTCAAATATTTTGCCAAACAGATCTACCATTTTTGATGCTCATAAATTATCATAAAAGTCCTCATGCTGCAGGTATTAGGAGGTGTAGTGAGGGGTTTGCATCTTTAATAAACTATGACAGTTCACGTTCATTGAAAAGTAAAAACGATTGATAAATCCATATAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa32742
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000074689 | Nonsense | 287 | 1231 | 4 | 25 |
| ENSDART00000144245 | Nonsense | 284 | 313 | 4 | 4 |
Genomic Location (Zv9):
Chromosome 1 (position 46406610)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 45244122 |
| GRCz11 | 1 | 45935917 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGAGGAGAGAGCCAAGCTGAAGGCCAAGAAAGAGAAGGAGGAAGAGGCTT[T/A]GAAATCTGCTGCTACACCTTCAACAGAGAGCAAGAAGCTGGAGAAAGCTG
Long Flanking Sequence:
GACAAAAGCAGACAAGAAGAAAGCCAAGAAGGGTAAGAAGGCGAATCTTGAAGATGAGGAAGGTGATGAAGATCAGGGTCAGAACGACATGGAGAACGAGCACAGGACAAAAGACACCAAAAAGGTGGAGGCTCCCGCTCCTGCTGCTCCTGCTTCAGACTCAGAAGACGAGGGCTCGCTTTCACGCAGGAAACCCAAGGCTAAAAAGAAAGGAGGCCAGAAAGCTGCATCTGACTCGGGAGACAGTGAAGATAACAGTGCGACGAAGGGCGGAGCAGGAGATGACGATGAATCCGATGATGATTCTCAAGCCGCACGCAAAAAGAAAAAAGGGAAAGCCAAAGCCAAGCCTGAAAGCGAGGAAGACGAAGGAGATGACTCAACCTTCAAAATGAAGACGGCTGCACAGAAGAAAGCAGAGAAGAAAGAGCGGGAGAAGAAGAAGAAAGAGGAGGAGAGAGCCAAGCTGAAGGCCAAGAAAGAGAAGGAGGAAGAGGCTT[T/A]GAAATCTGCTGCTACACCTTCAACAGAGAGCAAGAAGCTGGAGAAAGCTGCTTCACTAGACCTGGATGGAGCCGATGTTCAGGGAGAAGGTGAGACTTTCTGTAACACACTGTTCTGTCATTGGTGTTTACGTGGATCATCTTTAATAGTAATTATTGTATGGAGCAGTAATGCATATAAAGTAACAGTGATATAATGTAGAATGTTACAGAAGGCACTTTGAGGTTTCAAATGTTTATAAACCTCAAACAACAAAAAGAAGCTTTATCAAAAGTCCTGCCAAAATAAAAGTTTATGATTTTAGTTAGGCCTGGGTGATACTCGAGTGTGAAGTTATAGAGTGTGACATTGATTTGTTTGAATGAAAATCAGTTTTTCCCCAAAACATGATATTCCCCTCTGAGTATTTCCCCTGTATTTTCCAAAGAAGCACATAAACAGCATGGCAAATGATACTTTAAAATCTTATGCTCTGGAATGAAATATAACATGAACGCACA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa32743
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000074689 | Nonsense | 692 | 1231 | 12 | 25 |
| ENSDART00000144245 | None | None | 313 | None | 4 |
Genomic Location (Zv9):
Chromosome 1 (position 46415075)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 45252487 |
| GRCz11 | 1 | 45944282 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCACTCAACAGATCGGAGCCACCAACGTGCCCCTGGATACCATAGTGGAA[C/T]AAACCAAGATGGTGAAAAATGTGAGTATTTATTTATTTATTTATTTATTT
Long Flanking Sequence:
TTCCCAGTATTTCTGTGACAATTGAATGTTTGTAACACAAGAAAAGGCTGTTGAAAAGGCTTAATATTGAAGCCATCATGTCCATTTGAATCTACAGTTTATCATAATCAAATGTTTATTAAGGAAAAGCGAATAGTAATCATTTACCTTAGTATTGCATTGATTTATGAATCAAGATTTGTTTTTAATGATCATAAAATGAACTGTGTGCAGAAACGCAGGCAGGAAAACCTGAAGAACATAATTTTGGACAAGCTCCGAGCTCCCGTGGTTTGTGTGCTGGGTCATGTGGACACAGGAAAGACCAAAATCCTGGATAAGGTGCGTTTCAAAGTGCCCGACATGGACTTGAGCTCATGTGTGCTTTATTTGTGTTTAATGTTCTTTTGTTCTCGCTTTCTGTCTATCAGCTGAGACACACACATGTTCAGGATGGAGAGGCTGGAGGAATCACTCAACAGATCGGAGCCACCAACGTGCCCCTGGATACCATAGTGGAA[C/T]AAACCAAGATGGTGAAAAATGTGAGTATTTATTTATTTATTTATTTATTTTTAAATCCAATAATTCATGTTCATTTGTTCCATTTACTCATGTGATTATTTATGATTATTAAGTCATGCTTTTGTGGTATTAGTTTGACAGGGATAATGTGAAGATTCCTGGAATGCTCATTATTGACACACCTGGACACGAGTCCTTCAGGTACAAACTATACTTTTTAAAAAATTTAATAAATGTTTTTTCTTTCTTATCTTGTATCATAGTTTCTACAACCATGATGTTATTAAATGTTTTGTTAATCAACATATTAAAATGATTTTTAAAGGATTGTTGCACTAAACTGTTATGTTTTATTATATAATATAATATGTTGTTAAAATAAAATGTAATTTAGAGCTTTTTTTGCATAAAATAACAAAAAGGTGGCATCATTTCGAAGTTATGGAATTTTTAGACCTTCCAAAACCAATGTTTTAAAAAGAAATCAATATTTGGTAGAA
Associated Phenotype:
Not determined