ZMP

cdkn2b

Ensembl ID:

ZFIN ID:

Human Orthologues:

CDKN2A, CDKN2B

Human Descriptions:

cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) [Source:HGNC Symbol;Acc:1787]
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) [Source:HGNC Symbol;Acc:1788]

Mouse Orthologues:

Cdkn2a, Cdkn2b

Mouse Descriptions:

cyclin-dependent kinase inhibitor 2A Gene [Source:MGI Symbol;Acc:MGI:104738]
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) Gene [Source:MGI Symbol;Acc:MGI:104737]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa25583	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa32685	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa25583

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000054209	Essential Splice Site	42	125	1	2

Genomic Location (Zv9):

Chromosome 1 (position 25013550)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	1	25437248
GRCz11	1	26130962

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

ACGGAGTGAATGCCAATGTGGTTAACAAATTTAGAAGAACGCCTATACAG[G/A]TAGGTTTAGACGCGCTTTAAGAATAAACAACGGAAATAAACAAATGCAAA

Long Flanking Sequence:

TGCCAGTTACATTAGCCATAAAACATTAGCAGAACCTAATTTCTGTTTCTCTGCAGCCTCTCCTACTGTGTCGTAAACTCATGTCTTCCTGACTCAGCTGTTGTGCGCAGGCGCAGTATGACAGTACTGCACCACGGTTTTGCTGTGACGTTTATGACAGAGACAAGTCCGAACAAATATCTCGCTACGAAAAATTATTTTAAGACACAACACTTTGATAAACGAGTCAGTTTCGCTTATTTACGCATTATATTGGAACATGTTATTCATGGAGACCGATAAAAATAAATTACAGCGTTGAACTGATTGTTTTCGCAGTATCATCATCATTTGGTTTTACCTGTGAAGCGAATTAATTTCGAAAATCAATAAAGATGATGAACGTCGAGGATGAACTGACCACAGCAGCAGCCACCGGAAACATTTCCCATGTTCAGTTTTTACTTTCTAACGGAGTGAATGCCAATGTGGTTAACAAATTTAGAAGAACGCCTATACAG[G/A]TAGGTTTAGACGCGCTTTAAGAATAAACAACGGAAATAAACAAATGCAAATAAATAAATAAGATTAATTGCAGATATGTAACATTAAATTAGTAACATACAATTCAAAGACTTATTTTGTATTAAAGGTCATATTATTTAACAAATTTAGGCTATTTCATATTTTCACACCTGTTTGACTATATGGGATTTACTTTTCTTTTTTTTTTTTAAATATTAGGCTATTTGTGTATTTATTTTACTCATTTTAGCATGTTTAAGAACCTTTTAGGCTACTTAAACGGCCTGAAACATGTTTACCAATAGCGTGTTATCAACCTATATAATACTAACAACACTTTCTATCTTTTAGTAATGTCATTAATTTTAACATTATAATTTTAACTTATAGCTACATTCTTAGAAATTAGTCCGAAATAAGACAAGGAGTTTTGGATGTATTGTCAAAGTTCAAATTATTCAAAGAAAACTAAAATCTTATTGAAAACGAAAGTCCCAATG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa32685

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000054209	Nonsense	105	125	2	2

Genomic Location (Zv9):

Chromosome 1 (position 25011706)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	1	25435404
GRCz11	1	26129118

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TTTTAATCCGCTTCGGCGCCGACCCCAATACAAAAGATCACTGCGATTTA[C/T]GACCAGTGGATGTGGCACAACAGACTGGCAACGTAGACGTGGTTGAATTA

Long Flanking Sequence:

TTAAAATGATTATAGGAATCTTCATAATTAATCATATGAAAAATAAGAATTAGCTACAACACAATTTGTTGCATTTAATTGATTTACTGCCCGTGAATAATTTATTGATAGGCTAAAAGAGTAATGCATCATGCACAGCAATGTTCAGTGCCAGCATGTGCACTGCTTTCGTTCCTATTTAACCAAAAAGTATCTACTTTCCAGATTTCGAGTGATGGCAGTAAAATTATTGATTAAACAAACTTCTTTACAGTGACATCATGACGTTACTGGCGTTTATTTTTTCATGAGACAGCAATTTTCCCCCTCTCCAGGTGATGATGATGGGTAACGCACCTTTGGCTCTTGTGCTGCTGGAACAGGGAGCGGACCCTAATGTGCCTGACCCCGACACAGGGAGCACACCTCTGCACGACGCTGCCAGAACCGGATTCATTGACACCGTGCGGCTTTTAATCCGCTTCGGCGCCGACCCCAATACAAAAGATCACTGCGATTTA[C/T]GACCAGTGGATGTGGCACAACAGACTGGCAACGTAGACGTGGTTGAATTACTCAATCGTGTTTAAAATGTTTAAAGACTGCATCACTGCATAGCCTAGGCTACTTTAGGTGGTAACCTTATTAATGCACTCAAGTACTTATAATTCTCAATAGCACATGGTCATTCATGTAGTTTGGAGATTCTAATCATTTAAAATTTTATTTCTGTATCTTTTAAGTTTATTTATTATTATTATTTATTATTAGCTAGTCAATGGGAACTTCAATAAAAGGCTACAGACACAAACCATCATACGCTCATGCTAGCCTATAGTTCGCATAATAAAAAGTGTAGACAGCATTATGTCCAAAGATAAATAAATAATTAAATAACATATCCACCTATTTGTTTTTAACCTGAAAAGCATGGCGACAAACATTGAATCAAATGGCTTGCAACGCAAGGACATCCAATATTTTTGGCGAGCTCTTTCTTTTTTCATTTCTTCCGGTTAAACATG

Associated Phenotype:

Not determined