Busch Lab

ZMP

TLN2 (1 of 2)

Ensembl ID:
ENSDARG00000044271
Description:
talin 2 [Source:HGNC Symbol;Acc:15447]
Human Orthologue:
TLN2
Human Description:
talin 2 [Source:HGNC Symbol;Acc:15447]
Mouse Orthologue:
Tln2
Mouse Description:
talin 2 Gene [Source:MGI Symbol;Acc:MGI:1917799]

Alleles

There are 10 alleles of this gene:

Allele Name Consequence Status Availability
sa17241 Essential Splice Site Available for shipment Available now
sa13127 Essential Splice Site Available for shipment Available now
sa19370 Nonsense Mutation detected in F1 DNA Not yet available
sa9473 Nonsense Available for shipment Available now
sa44343 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa11842 Essential Splice Site Available for shipment Available now
sa32542 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa17241
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
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Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000023584 Essential Splice Site 192 2010 4 43
Genomic Location (Zv9):
Chromosome 25 (position 34091397)
Other Location(s):
Assembly Chromosome Position
GRCz10 25 32565577
GRCz11 25 33051004
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCGCCAYKCAGTGYGCACTKTCCACATCACAGCTGGTGGCCTGTACTAAG[G/A]TACTWCTGACAGATGAAGAGAAATGATGCYGMTAACATTATACACAACTG
Long Flanking Sequence:
CTAAGGAACTGAACTGTCATGCTTTGATATTTGCTTTATCCTGCTCTTCTGACTGGTTAATTCAAAATCCCTCAGCCAATTGCACGCTCCCAGTCTCATTATGTCCCGTCAAGGCAGTTTTCTCATGTAGTAAACACTTTAGCGCCCATCTTCGACACGTAAAATTTGATTTCGTGTGGTTCAGCTGATGCTGTCACAGTCGGTTAGCCTCGGCGAGCCTCTGATTGCCCTCTATTTGATTGTGTTACACTCTATCCTTGTGCTGATTTCATTCATTAGCCTGGGCCAGGTTGCTTCACAGTGTGTTTCTTTGGATGACGAATGTGTTTCAGGACATTATGATGAACCTGGCTAAAGCCGTAGCGAACGCCGCCGCTATGCTTGTGCTGAAGGCCAAGAACGTGGCGCAGGTGGCCGAGGACACGGCGCTCCAGAACCGGGTCATTACCGCCGCCACGCAGTGTGCACTTTCCACATCACAGCTGGTGGCCTGTACTAAG[G/A]TACTTCTGACAGATGAAGAGAAATGATGCCGATAACATTATACACAACTGCTTTTTAGGATGAATCAAATTATATTTAGCTAAGATATTAACTAATCATTCTAAAGGAAATTATTCAACCTTTCCAAAGTTGAAAAATGTTTTTGATTATAAGCGTCTTCTGTCAATATAGAGTAGAAACTGTACAATTATTATTATTACTCTTTAATAGAACTGTTTTTAATTTTAATTAATTTTAAATTGTCATTTATTTCTGCAATGCAAAGCTGAATTTTAAGTGTCTTTAATGCCTCACGATCCTACCACAATCCTTCTAATTTGCTGATTTGCAGCTGAATTATTCAGTTTTTGTTTGTTTTGGGATTTTTATAAACTGTACCTTGCGAAGGAACCTCCTTTATGGAATAGTGTGGTGGGACGGGGGAGATGGTGGGGTGTTATAGTGAGGGATGGATTGCGGATGAAAGTGAAGAGCGGGGTGCGGGTAGAGGATGAAAGTAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13127
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
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Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000023584 Essential Splice Site 389 2010 7 43
Genomic Location (Zv9):
Chromosome 25 (position 34080934)
Other Location(s):
Assembly Chromosome Position
GRCz10 25 32576040
GRCz11 25 33061467
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACGCAGCTGCCCAAAACGCCATCAAAAARAAGCTCATTCACAGACTGGAG[G/A]TGAGCAGATGCATTACAGGACATGTTACAGATANNCCTGTTGAAAGTGTTCA
Long Flanking Sequence:
GTATTTATGTCATAACATGCGTTATAGGTGAATCAAATAAGCTAAATTGGCCGTAGTGTATGTGAATGTTAGTGTATGGGTGTTTCCCACTACGGGGTTGCGGCTGGAAGGGCATCCACTGCGTAACACATATGTTGAATAAGTTGGCGGTTCATTTCGCTGTGGCAACCCCTGATTAATAAAGGGACTAAGCCAGAGGAAAATTAATAAACGACCCTTCATAGGAAATTGTGCTAAATGATCCCGGACGAGCCCCCACAGCTTGGTATTCAGTATATTAGAAACGTTGACTACAATTAAAAACACCTGACCCAAAGTTGATGAACTATATAAACTAATTTAGTAATCGTATCTGAACTGTTTTTGTGCAGGGAGCTGCGGCTTATCCGGAAAATGAAGACCAGCAGCAGCGGCTGAGAGAGGCGGCTGAAGGACTACGGGTCGCCACCAACGCAGCTGCCCAAAACGCCATCAAAAAGAAGCTCATTCACAGACTGGAG[G/A]TGAGCAGATGCATTACAGGACATGTTACAGATACCTGTTGAAAGTGTTCATATGTCATACTGAGTGATTCATTTGTGAATGATTCGATTCATATGGCCTTGAATCATGGAATCACTGATTCAAATTAATCAATCAGAAGACGTCTACAGTTGTGATATACAATTTTTATTTATTTGGTCACAGTAAGGCTTTAGTTACCAATTTACTGAATCACATTGATTCAGTCAGATAGAATATGTGGTTAAAGACTCACTGATTCAATGTTCCTGTCAGAGCAAGTCTCCATTAAATGATTTACTGATTTAAAATAATCCTATCAGAGAGAGTGTGTAGTTAAAGACTCACAGATTCATATGTTCCCATCAGAGAGTCTCCGGTGAGCGATTCACTGATTCAAATGTTCCAGTTAGAGCAACTCTCTAGGTAATGATTTACTGATTCAAATGATCAAATAAGAGAGTATGCTGTATGCTTACTGATTCAAATGTCCAGTTAGAGCG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19370
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000023584 Nonsense 703 2010 15 43
ENSDART00000023584 Nonsense 703 2010 15 43
Genomic Location (Zv9):
Chromosome 25 (position 34062492)
Other Location(s):
Assembly Chromosome Position
GRCz10 25 32594347
GRCz11 25 33079774
KASP Assay ID:
554-5506.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTCTTATCATATCTCCCTTTCTGTAATATTTCCAGCTTCCTCCATGCTCT[A/T]AATCCTTCCAAGAGGCGCAGACGGACTTGAACCACACAGCAGCCGAGCTC
Long Flanking Sequence:
TCCCGTTCGCTTCATTCGCCTGAGCAAATTTTCTCAGGAGACCTATAGTTTTACCGAGTCATGCGACTTCGGTAATATCGAAAAAAATTAATATTGCGGTATGACGGTATTTACAATACCGTTACATCCCTAATAATCACACTTGATAAAAAGTCAGCAGAAACAGGGGAATGGGGGAAGCCCCGTCCATTAGGGACCATCTTTTCCTCATCAGCATAGAATGTTAATCTTGTTTTTGAATCTGCCACTATGCTGACACGTAGGCATTTGCAGCTCCGCCCTCTTTCGAAAAGCTCACAATCTCATTTGAATTAAAAGCGACAGTCACTAAAATGGCACAATTAGGACCAAAGCCTAAAAGGGGCAGTTTTAAAGAGTTATAAAATATTATTTGTTGGGTATTTTGAGCTGAAACTTCACACTCTAGGGACATGAGAAACTCAACCAAAACTCTTATCATATCTCCCTTTCTGTAATATTTCCAGCTTCCTCCATGCTCT[A/T]AATCCTTCCAAGAGGCGCAGACGGACTTGAACCACACAGCAGCCGAGCTCAACCATTCGGCCGGGGATGTTGTGCAGTCTTCGCGCGGGAGCAGCAGCCAGCTGGCCGTGGCTTCTGGGAAATTCAGCCAAGACTTTGACGAGTTTTTAGACGCTGGCATCGAGATGGCAGGACACACTCAGGTACAGCTTCAGTGCCCTCTTAGAGAAGGGAGACCATTTGTGTTTCTCCACCTTACATACAGTTGAAGTCAGAATTATCAGCCCTCCTAAATATTTTTTGCCCAATTTTTGTTTAAAGAAAAGAAGATTTTTTTTCAACATAAAAAAACAAACAAAAAAAACGAACCATCATTGTATTAATAACTAATTTCTAAAAACTGATTACCTTTTTTTCCCCATGATGAAAGTAAGTAGTATTTGACTATATATTTTTCAAGATACAAGTTCAAGTTCAAGTTGCTTTATTGGCATGACATTTAATACAGTATTGCCAAAGCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9473
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
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Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000023584 Nonsense 703 2010 15 43
ENSDART00000023584 Nonsense 703 2010 15 43
Genomic Location (Zv9):
Chromosome 25 (position 34062492)
Other Location(s):
Assembly Chromosome Position
GRCz10 25 32594347
GRCz11 25 33079774
KASP Assay ID:
554-5506.1 (used for ordering genotyping assays)
KASP Sequence:
CTCTTATCATRTCTCCCTTTCTGTAATATTTCCAGCTTCCTCCATGCTCT[A/T]AATCCTTCCAAGAGGCGCAGACGGACTTGAACMACACAGCAGCCGAGCTC
Long Flanking Sequence:
TCCCGTTCGCTTCATTCGCCTGAGCAAATTTTCTCAGGAGACCTATAGTTTTACCGAGTCATGCGACTTCGGTAATATCGAAAAAAATTAATATTGCGGTATGACGGTATTTACAATACCGTTACATCCCTAATAATCACACTTGATAAAAAGTCAGCAGAAACAGGGGAATGGGGGAAGCCCCGTCCATTAGGGACCATCTTTTCCTCATCAGCATAGAATGTTAATCTTGTTTTTGAATCTGCCACTATGCTGACACGTAGGCATTTGCAGCTCCGCCCTCTTTCGAAAAGCTCACAATCTCATTTGAATTAAAAGCGACAGTCACTAAAATGGCACAATTAGGACCAAAGCCTAAAAGGGGCAGTTTTAAAGAGTTATAAAATATTATTTGTTGGGTATTTTGAGCTGAAACTTCACACTCTAGGGACATGAGAAACTCAACCAAAACTCTTATCATATCTCCCTTTCTGTAATATTTCCAGCTTCCTCCATGCTCT[A/T]AATCCTTCCAAGAGGCGCAGACGGACTTGAACCACACAGCAGCCGAGCTCAACCATTCGGCCGGGGATGTTGTGCAGTCTTCGCGCGGGAGCAGCAGCCAGCTGGCCGTGGCTTCTGGGAAATTCAGCCAAGACTTTGACGAGTTTTTAGACGCTGGCATCGAGATGGCAGGACACACTCAGGTACAGCTTCAGTGCCCTCTTAGAGAAGGGAGACCATTTGTGTTTCTCCACCTTACATACAGTTGAAGTCAGAATTATCAGCCCTCCTAAATATTTTTTGCCCAATTTTTGTTTAAAGAAAAGAAGATTTTTTTTCAACATAAAAAAACAAACAAAAAAAACGAACCATCATTGTATTAATAACTAATTTCTAAAAACTGATTACCTTTTTTTCCCCATGATGAAAGTAAGTAGTATTTGACTATATATTTTTCAAGATACAAGTTCAAGTTCAAGTTGCTTTATTGGCATGACATTTAATACAGTATTGCCAAAGCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44343
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000023584 Essential Splice Site 1166 2010 24 43
Genomic Location (Zv9):
Chromosome 25 (position 34036817)
Other Location(s):
Assembly Chromosome Position
GRCz10 25 32619114
GRCz11 25 33104541
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGCTGCCGTGGGTCAGAGTTTGCCACGCAGAGATGACATTTCCCTGGAGG[T/C]AACCAATAAAATCATGTCTGTGTCAGTACCTGCCCTCTTTTCGTTACAGG
Long Flanking Sequence:
TGGTAATCTGATACCTTGTGATAATTTCCAGAATTATCTGACAAACCATATTTACCACTCACTGTTATTAATGTTCATAACACCATTAGGAACTGCTGTGGAAGAGCTGAAATTAGGATATAGTAATAGCCATTTGGTTTCTAACAGACTGTAAGTGATCAACCATTCACAATAGCAAATTAACTGACCAATCAGAGTAGAGTTGCCTTTGGGGTTTAGCGATGTGGGTTTTTTTAAGATGTTGGATGAAAAGAGCTGATGCAGCAGTGTACATTATGACGAAATAAATATTTTTTAACCTTGAGTGGATGTAAATCTAATGTAGGAGAACAAAACCTAGTAACCCATTCTGTGCTGTTGTGACAGGGACAAGGCTCCTGGGCAGCGGGAGTGTGACCAGTCCATCGACAGCATCAATAAGAGCATCAGGGACATCGAGCAAGTCTCTCTTGCTGCCGTGGGTCAGAGTTTGCCACGCAGAGATGACATTTCCCTGGAGG[T/C]AACCAATAAAATCATGTCTGTGTCAGTACCTGCCCTCTTTTCGTTACAGGTGCTCTGGAACAGGGTTGCTTTTATGTCTGCAACAGCTCGTCGTGATGGCAAGGATGATAAATCTATTAATAAATCTATTAAGGACTTGGAATGCTGCTTAACAAATAAAAACAATATAAATAAAAAGGAATGTACTGATTAAATTAATACAAATTAATAAAGTTATCAGTCTATTTATTAAAAAACGTGAAACTTTTCATCGTAACAAACATTTTTAAGGAAACTATTTAATTTGTTGAAGATTTTATTTAAATATTTAAACAACAGTTTGTCACGTCACACGTGAGAGCATCTAAATAATATTTGTTTAAAACATGCTAGATTAAATTTATATTATTTATAATATTCATTAGATTTATAGAAGCAATATCACACAAGTAGCAGTGCAATATGGCTGTATATTGGCACTGCTGGGTGGTTTACGATCAACCCAAGCTCATTCTCAAAAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa11842
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000023584 Essential Splice Site 1627 2010 34 43
Genomic Location (Zv9):
Chromosome 25 (position 34018354)
Other Location(s):
Assembly Chromosome Position
GRCz10 25 32637633
GRCz11 25 33123060
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GACGAGGGCTCTGGAAGCCACTATTGAGTGCATCAAACAAGAACTCACTG[T/C]ACGKAACATTATGTGTGAATATTRAWCCCTCATACTGATGTCATTTCATA
Long Flanking Sequence:
CAGGGCTTTGTTTTAGGCCTGCTTTGTTTTCTTGGGTTTCCTCCTTTGTTCGTTCTGCATTTATAAATTTGCCTGAAGCAAAAGCTTGGAAATCTGTTACTAACCTCAGCTGCTGTCCATTAAAAGGTTCGGTTTTATCTCTTGAACTTTTCATAATGATTTAGATTGTACTTTCTTGTGTTGCAAAGAACAGAATCCTGTCGGTTTTACTGTGCTGTTTGATTCAGTTGTTCCTGTCGTAACATTGCCTCTGATCTCTTTCAGTGCGTGAGGTGAAAAACTGGCCACAAAGCTGTTGACATTCTCGCTCACTTGAGACATTGTACTCAGAGTAAGAAATGCAGCTTCAACTTTGACCTTACTGTGTTTTCTGATATTACAGGTCATGGTGACGAACGTGACCTCTCTGCTGAAAACTGTGAAAGCTGTGGAAGACGAGGCCACTCGCGGGACGAGGGCTCTGGAAGCCACTATTGAGTGCATCAAACAAGAACTCACTG[T/C]ACGGAACATTATGTGTGAATATTGAACCCTCATACTGATGTCATTTCATATATTGTACCTTTCTGCCATTATTCTTTACCTTCATATGGTTTCACACCTGCATGACAGATTCTCTCATGTGAAAAGCAAAAGATCAATTTGGAGCAAACGACACTGGACCCATTACTTTTATTTGTCTGGAATAGTTCCACAAGAGAATTCAAGGTTCAGAACCCTGCTGAAAAATCCAGCTTAAACCAGCCTAGGCTGGTTGGCTGGTTTTAGCTGGTTGACCAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAATCGTTTCGGTTAACATAATTTAAGCACATTTTGAGACTATATGCTAATTTGTAAAACAATATGGCCGTGAATTGGTATAGATTAGGCTCAGCCTAATTCGTTTTTAACCCAGGTAATACAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32542
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000023584 Nonsense 1914 2010 41 43
Genomic Location (Zv9):
Chromosome 25 (position 33996869)
Other Location(s):
Assembly Chromosome Position
GRCz10 25 32659118
GRCz11 25 33144545
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTAAACAGGTGGCGGCGTCCACTGCACAGCTGCTGGTGGCCTGCAAAGTC[A/T]AAGCAGACCAGGACTCTGAGGCCATGAGGAGATTACAGGTCAACTTTTCC
Long Flanking Sequence:
ATGAACACATTCTTGCTGCTTAGTTTTTGATTGTTCATTTTAGCGTTTCGTCTTTGACAATGTGAAAGATATACCTGTAGAAAACGATAAAAATGTTCTGAAGCTTCTGAAATTACTACTGTAAATACATATAAAAGTAACACCAAATTACCCACTGCTCTTCAGTGGTTTAAACATGACTAAAATAACACTTTGTGATATGTGACGCAGGTGGGCTCCATCCCTGCCAATGCAGTAGATGACGGCCAGTGGTCTCAAGGTCTCATATCAGCTGTAAGTTGAGCTTTTTCTCACATTTCTTAGTCACTTTGACCTGTATTATAAGCAGGATGACGGTGATGAATTGTGTGTTTCAGGCACGGATGGTTGCGGCCGCCACTAGTAACCTGTGTGAGGCGGCGAACGCTTCGGTTCAGGGTCACGCCAGTGAGGAGAAGCTCATCTCTTCTGCTAAACAGGTGGCGGCGTCCACTGCACAGCTGCTGGTGGCCTGCAAAGTC[A/T]AAGCAGACCAGGACTCTGAGGCCATGAGGAGATTACAGGTCAACTTTTCCCATGTCCCATGATGCTTTACCTGAATTACGAAAGTACAGTCGCTTCCATTAACGCACTTTATCAGGACACTTTTTCAAAATATCACTTTTTTTGTAATGAAATTGTAATCTAATCATGACAAAGTGTATACAGTTTAAAAAATGCAAAATGTTTATATTTATTAATTTGTTTATTTAATCATAATTATCACCTTTCTGTGGATTTACTCAAAAACTAAACCCAACTTTAACCCTACTATTAATAAGCCACTAATTAGTAGTTTATTGAGGTAAGAGTCTTAGTGAAAAAAAAAACTTGAGATTGGTCAACAGGTGGCGCTATACACCTTAAAAATGTCAAAAATGCTGTATTTCTATTGGAAATGAACACATGTAATGCCTTTGTTTGTTTGTTTTTCTAATCATTGTCTTTGTGTTCACACAGGCTGCTGGTAACGCGGTCAAGCGAGC
Associated Phenotype:
Not determined