Busch Lab

ZMP

thbs4b

Ensembl ID:
ENSDARG00000020072
ZFIN ID:
ZDB-GENE-020708-4
Description:
Thrombospondin-4-B [Source:UniProtKB/Swiss-Prot;Acc:Q8JGW0]
Human Orthologue:
THBS4
Human Description:
thrombospondin 4 [Source:HGNC Symbol;Acc:11788]
Mouse Orthologue:
Thbs4
Mouse Description:
thrombospondin 4 Gene [Source:MGI Symbol;Acc:MGI:1101779]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa37222 Nonsense Mutation detected in F1 DNA Not yet available
sa32331 Essential Splice Site Available for shipment Available now
sa37223 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa37222
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000102572 Nonsense 30 949 2 22

The following transcripts of ENSDARG00000020072 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 21 (position 5375911)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 4972055
GRCz11 21 5136620
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCGCTTATATAACCTTTAAATACATTTTCCCCCTCAGTGTATAACCTCT[T/G]AACGTCACCGGACTGTCTACCGGATCTACTGCATGGTGGTTTGGCAGAGC
Long Flanking Sequence:
CCAGCACTTTTCAAAATATCTGCTTTTGTTTTCAACAGAAAAAAGAAGCTGTTACGAGCAAAGATGATGACAGAATTTTCATTTTCGGGTGAACTATCCCTTTAAATTAGATTTCTCTTTCTTTGTTAAAGGTTTACATCAAGCATATTAGATATGGTTTAGTTTCCACATTTAGACACACACCATTCTCCCATTCCCAATGCCAAAACATTGGAAAGCCAGCTGCTATTAAACATGTTTCAGTCAAGCTGTTTTATGCCATCCTTGCCATTTACAAACTTCAAAGAACTACAAATCCTTCAAGATTTACTTGGCAACATGCAACCAGCTAAATAAACAGCAACAGCATTTACAGTCTAACGAAAATGACATCAACCTAAAAATACTTGGGCATCACTCCCAGCATGCATTAGCCCTGAGGAACAACTGCATGTTTTTGTGTGTGTGTGTAGCGCTTATATAACCTTTAAATACATTTTCCCCCTCAGTGTATAACCTCT[T/G]AACGTCACCGGACTGTCTACCGGATCTACTGCATGGTGGTTTGGCAGAGCAGGGAGTAACGGAGCTCTATATTCTCACAACGTTCCGGATCCAACCTGGAACCGGAAACACCATATTTAGCCTGTACAATCCACGAGACAACAGCAAGTACTTTGAATTCTCGGTGTTTGGAAAAGCAAATAAAGGTAAACGTTTGACTATTCCCTACTTTAGATATTCATCTGTATGTTGTGTGTGATGTATGATGTGCGATGCATCTTAAAAGTAGGTCCCAGTTTTTGTTAAGTGACCTTAATCACTTTGTACTTACTGTACTTTGTCATTTGGTACAATGCACTTATTGTGTACATACAGCTAAAGTTAGAATTACTGGCCACTTTATTAGGTACACCTGGCCAACTGCTCGTTAACGCAAGTTTCTCATCAGCCAATCACATGGCAGCATCTCAATGCATTTAGGCATGTAGACATGGTCAAGATGATCAGCTGCAGTTCAAATC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32331
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000102572 Essential Splice Site 220 949 5 22

The following transcripts of ENSDARG00000020072 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 21 (position 5384560)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 4980704
GRCz11 21 5145269
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTTGTTTGTCTGTTAAAATGATTAAATTTGGCTTTTTTGTTGTTTGTAA[A/G]GGGCTTAACACGAAACAGCTTACAACTCAGATGCTGGAGCTAACAAAGGT
Long Flanking Sequence:
TAGGCATCGTCGCGCACCTTTCTCACCCCTCCCCACCGCGTCTCTCCTCAGACATGTCGCGCGCGCACCCTGTCAATCACCACCAAACCACCACCTCTCCTGACAGCTTAGCGGGACGCTGCAAAATAAACCCTGACACTCTGACCAATGTGAGGAGAGTTTACTCACACGTGACTTGTTTTAGCGCTTTTGGTCCGATTAGAAACTTTGCAGTGTGAAAGCGAACCGCTCCAAGAGCAAAGAGCAACAATGTAACAATTGTAATCTGTTTCGGAACAACTGAATCGATTCACAGGTGTGAAAGCACCCTAAGAATGAACAGTACTTGTACAGCATTGATCATAGTTCAATATTTAATAATGCATCACCAGCAAGGATTTTCCATCAAGAATCACTAAAGCAATATGAGTCCATTTACTGAGTGCAACTTTGAGAAAAAGAGCTGGAGTAAGTTGTTTGTCTGTTAAAATGATTAAATTTGGCTTTTTTGTTGTTTGTAA[A/G]GGGCTTAACACGAAACAGCTTACAACTCAGATGCTGGAGCTAACAAAGGTCATTAATGAGCTGAAAGACGTTCTTATTCAGCAGGTAAAATCTTTCCCGTCTATTACTCATTTGTACCCTTTTGTTTAATGTTCCTAATTTCCACCATTCCTTATTTACGACTGAGATGTCCTTGTGTTTGCACGCATGTTTACAGGTGAAGGAAACATCTTTCCTCAGAAACACCATCTCTGAGTGCCAGGCCTGCGGTAAGACGTCTGAATGACCAAAACATCCATTTGGATGTTTTGCATATTGATATTTGCCCTTTTATTTGGTAATATAAACATCCATTTGGTATTAAAACATCCATGTGGGAAACAAACACTAGTCGCCAAAGCTGAAGTAAATTTGAAGCAGGAGTGCAATCATGAAACTTGATCTAATGCTATATGTAAGTTTTGGACTCTTTTAAAGCATAAAAATACCATATGTTTACAGATATTTAAGAAACATGCTTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37223
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000102572 Essential Splice Site 473 949 11 22

The following transcripts of ENSDARG00000020072 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 21 (position 5394827)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 4990971
GRCz11 21 5155536
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGGGTACCCTGATGAGAGGCTGCGCTGCCGAGACCCAACCTGCAGAAAGG[T/A]AACCATGGCAACAGTGCAATCGATATTGACTAGCTTAGGGCTTTGGTGAC
Long Flanking Sequence:
GTAAAGGGCCAGATAATGGAGGATGCACAGCGAACTCCATCTGTGTGAATTCTGTGGTGAGAATTCTGTCTTCTGTTCGTTCATAATGCATCTCCATGATCGCACATGCATGCAAAGCAAAATAACAGTGCCTCAGAGTGTGTTATGCTGTGTGTAGGGATCATATCAATGCGGGCGATGCAAAACCGGATTCACGGGAGACCAGATCAGAGGTTGTAAGCCAGAGAAAAGCTGCGGAAACCGTCTGCAGAACCCTTGCGATCCCAATGCACAGTGCACAGAGGAGAGAGATGGCACCATTACATGCCAGGTACACCTTTAAAGCACAAAAAATTCACACGTATTTAAAAAGAAAAGGCATTAAGCTCAAAGTCGAATGCTGCGTGTGTGCTAGTGTGGCATTGGATGGGCTGGAAATGGTTATCTCTGCGGGAAAGACACTGACATCGATGGGTACCCTGATGAGAGGCTGCGCTGCCGAGACCCAACCTGCAGAAAGG[T/A]AACCATGGCAACAGTGCAATCGATATTGACTAGCTTAGGGCTTTGGTGACATCACTTGCCTGTCTCTGGGAGAGCTCATCCATATTGTGCCCTCAATACCAGGATAACTGTGTTACCGTTCCAAACTCGGGACAAGAGGACGCAGATGGCGATGGGAAGGGTGACGCATGTGACCCAGATGCAGATGGAGATGGAATATTGAATGAGCAGGTAAATGCACAAATATGCATGTGCATTCATGCGATGGTTGTTAATGTATTGATGCACTGCAGAATCTCAGTTTCGTAGGTCTAGTTATGAAGCAAATAAAGACCAGATCTTGTTCCTGTGTATACTGTAGGATAACTGCTGGTTGACGCCAAATATAAATCAGCAGAATAGTGATAAGGACAGCCATGGTGATGCTTGTGACAACTGTGTCCGAGTGGATAACCCAGACCAGAGAGACACAGACTCTGATGGACTCGGAGATGCATGTGATGATGATATGGATGGAGATG
Associated Phenotype:
Not determined