Busch Lab

ZMP

lepr

Ensembl ID:
ENSDARG00000070961
ZFIN IDs:
ZDB-GENE-080104-1, ZDB-GENE-080104-1
Description:
leptin receptor [Source:RefSeq peptide;Acc:NP_001106847]
Human Orthologue:
LEPR
Human Description:
leptin receptor [Source:HGNC Symbol;Acc:6554]
Mouse Orthologue:
Lepr
Mouse Description:
leptin receptor Gene [Source:MGI Symbol;Acc:MGI:104993]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa12953 Nonsense Available for shipment Available now
sa323 Nonsense F2 line generated Not yet available
sa38556 Nonsense Mutation detected in F1 DNA Not yet available
sa5372 Nonsense F2 line generated Not yet available
sa1508 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa12953
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000079173 Nonsense 81 988 5 20
ENSDART00000104616 Nonsense 91 1088 3 19
Genomic Location (Zv9):
Chromosome 6 (position 30911269)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 31232185
GRCz11 6 31219099
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTCATGAAAGTAACTAACAAGAGAATGCAATCTCTTTTCAGGAAGCTGTT[T/A]GGACAYCCTGTGCTGGCTTGAAGGTGAAYGGGAAAATTTGATTTGTAATG
Long Flanking Sequence:
ATCAATTCTCATTACTTTCTCTTCACTGTGGTGGTGGGCCTCGGGGCAGTGATTAAAGCCCTCAACTAAATATATAGCATTTAAATGCAAAACAAGTTTGTTTGCAATCCAACGTGTGAAGTGGCTCTTCAAAAACAGAAAAAGAATTGATACAAATACTTAGAGGTAGATTTTTTTTTTTGTAACACTATAAAGCATTCATAAAACATTCCCCAGATATTTTGTTCTTGGATTCCTGCAAGGGTCTTAGCTTAAAACTTCAACAACAACATCAAAAAAAAAAAAAAAAAGATCTGGCCAGAATCTCAATTAGACTTAATATTTGATGTTTCATTCCGATTCAAAGTATCGCGCTTGTATCCTCATGTTATTTTCACATCATGTAATGAGGCTGTGTCCTGAATTCTAACAGGAATTATTGAGGCTTCTAATTGCAACGGGCTGGGATGATTCATGAAAGTAACTAACAAGAGAATGCAATCTCTTTTCAGGAAGCTGTT[T/A]GGACATCCTGTGCTGGCTTGAAGGTGAACGGGAAAATTTGATTTGTAATGCAAAGACCCGTAGAGCAGCAGCAGCTTCCACTCTGGTCAGCGTCAGCCCTCATCAATTAGTGTGAGTCTTCTGTTTTCAGTCAGCTGTCCACTGACTAATGATTGGATAAATGGCAGCCAGTGCAGTGTTGCTTCTTTATACTATTCTACTCTATGCTACACTATTAGACTCTGTTCTGTCTGTAATTCTTTCAACTTTTTTATTACTTAATATTTTGTTTAACGTTTTCCACAATGGCTGAACCATTAATTGTCAAAACGACTGAATTAAATATCTGCATGATCAAATTCCAAAATAACTACAGTTTAGCTAATTACAGTATCAGTATCATGGCAAATATTTAAATCTGTATTCGTGCTCTTGCTGACTTATAGATTCAAAGATACAATTATAATGTATAGGTATGAAACAGCTTCAGTTTGTATCTTTTTAATCGCACAAAATCTCTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa323
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000079173 Nonsense 374 988 10 20
ENSDART00000104616 Nonsense 383 1088 9 19
Genomic Location (Zv9):
Chromosome 6 (position 30893021)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 31213937
GRCz11 6 31200851
KASP Assay ID:
554-3312.1 (used for ordering genotyping assays)
KASP Sequence:
AATTTCAAATCTGCTCTTTTCCAGGAAGGTTTAACGCAAATATTACCTGC[G/T]AAAGCGAGTATTCATATGTGGACACCATGATCTGTAAGTGGAATCAGAGC
Long Flanking Sequence:
AGCTTGGTCAGATGTGTTTGATTCAGGTGGAAACTTAGCTCTCCAGGACACTGGCCCTCCAGGACAGAGTGTGGACACCCCTGGCTTAAATGGCCCTCTATTCTGTTTTTCTCCTCAAAGTCAGTTACATCCCTGCTGAAGTCTTCACAACGCAGGAGTCAGAGGTGACAGTTTACTCTGTGTTCCACAACCGCAGCTGGAGCGCCAGTAAAGCCGTGTGGTTTCTGAACGGCAAGATGAAGATACCAGAAAGCCAGTACAGAGTCATCAATGAGCAGGTCAGCACAGTCACTCTAAAGATGGACAAAGCAGGATTTGACACTCTGATGTGCTGCCTCACATTGGGAGAGAAATCTATGTGCTCCATCGCCTATGCCAAAATATACACAGAAGGTGACTTATCAATTATTGAGGACAGCGGATAAAATGTTGCTTGTTGAAAAGCTAGACAATTTCAAATCTGCTCTTTTCCAGGAAGGTTTAACGCAAATATTACCTGC[G/T]AAAGCGAGTATTCATATGTGGACACCATGATCTGTAAGTGGAATCAGAGCAATTGGGCACAGGCCAGACTCCTTTACAGGTATGAAAATGTTTTCCGTCCACCTTTTTATTTATGATGCTGTGCATAAATGCATAATGCACTTTCATTGAACTGTAAACAATCAGTGAAAACTGGGTACAATTTTGTGCTATTATTCTCCACACAGTTCATTCTTAGAATGTCAAAAAGCAGCTTGCATTACAGTTAACAAATTATTATTTAAGTAGACCATGAATAACCCCAAAACTTAGAAATGAGCCTATCTGCAGCAAAAGTAGGGTTAGGATTATTGTTCCTTAAACCAGAAGTGCAAGCCATAATTTGAAATGAGTAAGTCACAGTCTTGGGGTGCATTTTGTTAGTCAATTAAGGTCACAAGTTCTCTTGCTACAATCATAGTTAATCAATTTGGCATTTGCCGAATTCATCATTTCAATAACTATTCGCAAGCTATGACGCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa38556
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000079173 Nonsense 441 988 11 20
ENSDART00000104616 Nonsense 441 1088 10 19
Genomic Location (Zv9):
Chromosome 6 (position 30892080)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 31212996
GRCz11 6 31199910
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGAGATCACAGACAGTGCACCTTAAGCCAAATCAGCATGATCTTTTGCTA[T/A]AAATTCTGGCTTGAAGTGGAAGGAGGACGTGGCCAATCGTTTCCTGTCTA
Long Flanking Sequence:
TAATCAATTTGGCATTTGCCGAATTCATCATTTCAATAACTATTCGCAAGCTATGACGCAAACTGGTATGGTTGCAACTACTCCTCTAGAGCTGTAGTTACAAGCATAGTTCCTGGTTCTATGTCCTATGCCCTATTCTTTTCGAATGTTCCATCATCCACTTTGAATGACAAAAAAAAAAAGGATTTGAGAAAGAATATGTTTGAGCGATCAGCTTCAGATTGACAATTGCGCTCCCTTCATAGAAATATACAAGAATACAAGATACAAAAGAAATATACGTTGTATATGTGCTGTTTACATAAATATGGAAAACAAATGCATGTTTTTACCAAAACTAATATTGGATTTATAAAAGATGCATATGGGTGTCGTAGACAATACAGATCAAAGTGCACTGAAGAAGCTGAAGAAGACACGTCTTTGGTGAAAGAGTGTCCATCTAAAGCAGGAGATCACAGACAGTGCACCTTAAGCCAAATCAGCATGATCTTTTGCTA[T/A]AAATTCTGGCTTGAAGTGGAAGGAGGACGTGGCCAATCGTTTCCTGTCTACGTTACGCCTATTGACTATGGTGAGCTACAAAGTTTATTCTGAAAAAAGTTAAGATGTTAATTTTGACTTTGATTACAGACTGAATTGCTGACTGGAAATTAGGATAAATTCAATACTGAAAATTCTATTGCATATGCCAATGTGTCAATTTCAGATGTTTGTATTAACTCTTATATTCTTATATATATATATATACACATACAGTTAAAGTCAGAATTATTAGCCCCCTTTTGATTTTTTGTTCTTTTTCAAATATTTTCCACATGATGTTTAACAGAGCAAGGGCGTTTTCACAGTATGTCTGATAATATTTTTTCTTCTGGAGAAAGTCTTATTTGTTTTATTTCGTCTACAATAAAAGCAGTTATTAATTTTTTTAAAACAATTTTTGGGACAAAAATAATAGCCCCTTTAAACAATTTTTTTTTCGGTAGTCTACAGAACAAACC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa5372
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000079173 Nonsense 554 988 13 20
ENSDART00000104616 Nonsense 554 1088 12 19
Genomic Location (Zv9):
Chromosome 6 (position 30890495)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 31211411
GRCz11 6 31198325
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGTASAAGTTCGCTGTAAAGACGTGAACGACACTGGATACTGGAGCGACT[G/A]GAGCAATAGTCACATTTCCACTGTTTTCAACTTRAAAGGTAAATTTTACA
Long Flanking Sequence:
GCCTGTATACGGCATGCAGTACGAGCTGCAATTCAAGGCTTTGGCTGGAATGGCAAATACGCAATGGAAGGTAATAATATGTTTTCGTAAGCTGGGGTCCCAGGTGGACAAAGAAACCAGAAAGATTAATAAAATATACCGGAGTAAATTCTTCATGAAAAGTGCTCAATCAAAGAAGGCAAGCAATAAAATTCTGCGGTCTGATCTTTTCAGAGGTATAATTGAAATATTTGAAACTGAAATTTGATCCTAAATTAAAAACAGTATTATCCTTACTTCGCTTACTAAAATTAGAACTTTTATCAGTAGAAATCTGGTTGCACTCGGAGATAGCATCTGTAATTTTCTCTGGCATTTACAGATGAGTGTTATATGTCATCTACAGGTCATTGGTCCTCTATTGGAACCACAGGCAGAGATTCAGCTTGAGGAGTCCTGTGTTCACTTTAAAGTAGAAGTTCGCTGTAAAGACGTGAACGACACTGGATACTGGAGCGACT[G/A]GAGCAATAGTCACATTTCCACTGTTTTCAACTTGAAAGGTAAATTTTACAGTAAAGTTATGCTACTATTAGTTATATAGCAGAATTCTTATATTGTGCCCTGCAATTTATTTGGTAATCACACCTAAAGGTCATTCTGGTTTCAAAATAGCAGATATTGTTTTTCTATGATATTAATTTTCAAACGATTTAGATTGTTCATTGTTTCTCTGGTTAGTCATAAACCATTTAATGAGCAACGACTTGTTATCAAATCCACCATTTTCGGACTGACTACTGTGTTAGTTTTATCATTACAGTTGATTTTGTAAATGTGACCCTGGACCACAAAAATGCCTATGTTGCACTGAGGTATTTTTGAGAATAGCCCAAAATACATGGAGTCAAAATGATAGATTTTTATTTATGCCCAAAATGATTAGAATATTCCAAGTAAAAATCATTTTCCATAAAAATAAAGTAAGTTTCTATAAGTATATCAAAACTTAATTTTTGATTAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1508
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000079173 Nonsense 807 988 19 20
ENSDART00000104616 Nonsense 830 1088 18 19
Genomic Location (Zv9):
Chromosome 6 (position 30881667)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 31202583
GRCz11 6 31189497
KASP Assay ID:
554-1432.1 (used for ordering genotyping assays)
KASP Sequence:
TACAGGATGAAAAAACTCATGTGGAAGGATGTTCCAAATCCCAACAAGTG[C/A]TCTTGGGCCAAAGGAATGGACTTCAGGCAGGTTAGTGTGACCTACTGTTA
Long Flanking Sequence:
AGAAGATAAACACATTGAGAGAGATTTAAGACGTTTGTTTGATGCTATAGTATATATTGATTTTGTTAGAATTAAAGCAAGGCATTGTAAGTTGTATCATATGCAATATTTAAAAGACAGAATATTGATGAGAAATACATACATGAGATTACAGTGGGATATAAATGTATAAGAAAAGTGAATTACAATGCAGTAATTTGCTTGAGGGTAAATATTTCACAAGCTCTAACATAGACAACTACAAGTGTATGGCAACTAACACAAACATAATACTACTTTTCTGACAAGACTAGACCAGACACTCTGGTAATATCACCACAAAGATATGTGTACAAAAGCTTAATAAAAGGAGTAGTGTAGAAAGTTAAATAATTAAATATGTACAATAAAAAATATGCATTTATCACAGTACAGTTCTGCTGAAATTAATTTTCATATAATCCATAATCTTACAGGATGAAAAAACTCATGTGGAAGGATGTTCCAAATCCCAACAAGTG[C/A]TCTTGGGCCAAAGGAATGGACTTCAGGCAGGTTAGTGTGACCTACTGTTATAGAAACATACTAGATTCAAGAGACAAAAGATTATTGTTTTTTACCTGGTTGGGTGATCACCTTGCATGTTGTATCTTAGCTCATGTATGACCATAAAAATATCAGTTTTAAAAACAAACACTTTTTTGTAAAGGTTAACAGCAAGTAATAGTATGCACTGCAAATTTTAGAGTGTGTATGTACTGTAAATAAAATTCACACTGCATAAAGTGTTGATGATTTGTGTTTTGCTTACCTGGTTCCCTGATAATATTATCTTTCTGAAGTCATTTTACCCCCTGTAATTTAGGTGAAAATTGTCATTTAGAAAATATATGCTTAAAGGTGCTGTATGTAAGTATTTGACTCTTAGAAAATACCATACTATGTTTGCAGATATTTAAGAAACATTCTAAGTGAGCATTCTTGTTTATCTACAAGCAATGCTGAAGTCAGATAATCTGCTCTGA
Associated Phenotype:
Not determined