Busch Lab

ZMP

map3k5

Ensembl ID:
ENSDARG00000005416
ZFIN ID:
ZDB-GENE-030827-3
Description:
mitogen-activated protein kinase kinase kinase 5 [Source:RefSeq peptide;Acc:NP_001155222]
Human Orthologue:
MAP3K5
Human Description:
mitogen-activated protein kinase kinase kinase 5 [Source:HGNC Symbol;Acc:6857]
Mouse Orthologue:
Map3k5
Mouse Description:
mitogen-activated protein kinase kinase kinase 5 Gene [Source:MGI Symbol;Acc:MGI:1346876]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa32269 Nonsense Available for shipment Available now
sa32268 Essential Splice Site Available for shipment Available now
sa43368 Nonsense Mutation detected in F1 DNA Not yet available
sa17844 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa32269
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046641 Nonsense 684 1364 15 30
Genomic Location (Zv9):
Chromosome 20 (position 3067910)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 3021772
GRCz11 20 3034612
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAGCATGGAGAGAAGGTGGTTCTGGGTAAGGGCACCTTTGGAGTTGTCTA[C/A]GCTGGCCGTGACCTCAGTAACCAGGTGCGCTTAGCCATCAAAGAGATACC
Long Flanking Sequence:
GTACATAGTGCATGAGTGCATAGTGTGCCATTTGGGACGCAGCTAATGAAAATATTTGATTGATCATGTATTGTTGCGTGTAGTTAGGACATGGCTTAAGCTCGGTAGTCAGGCACGTTTGCTTCTGTTAGTGTCATCAATCTGGATTTTAGTCATCGTATGAGGAGTGACCGGTGGAAAAAAAACTCTCTAGTGTTTTGATTTTGTGTTGCAATAAACACTGCAAACCATCCTAAATACTGCACCTTAATAATGCACTCAGTTTACTGTAAATCAGACTGTCTACAGTACACTAAACATATAAGTATATTTGTTGTAAATCTTTCCAGTTCAAGGAATGTTTATGGAAAATGCCTGAAATGTGTATTGTTGTGTATATTTATGTACAATGTTGAGCGACAGAGAGGATGACGTGTTTGTGTGTGTGTGCAGTATGATTATGAGTACGATGAGCATGGAGAGAAGGTGGTTCTGGGTAAGGGCACCTTTGGAGTTGTCTA[C/A]GCTGGCCGTGACCTCAGTAACCAGGTGCGCTTAGCCATCAAAGAGATACCTGAACGGGACAGCAGGTGAGCAATTACACCTTTTAAGGTTTGTCTGATGAGATCCACTTTGAAATCCCTCTCGAAAGCAATATGCTTCCTTGCAATTTATTATTATTATAATTCAGTGTTTCCTCTAGAATTTTGTGGCGGCAGGTCTTTTACACAAATCTACCAACTATGGCGTTATTTCAGTGTGGTAAGCGCAGTATTACACGTCGGGATCGCATTTATTTCATGTAAATACGAGCATGCCAATCTCTGCTTGCGCGCCGATTTTCTCTGCTCGTGCACAAAACTTCTTGCACATCCTCAAACACGCTGCTCAAGCTCAGATCTTCTTGTGCGCTCTCAAATAAGCACTGCTGAAGTGCGATTTAGTGCGATTATGTAGTGACTATGTCTCCAACATTAATTAGATTTGCTAGGAATATTTATGAATGTCTCTAATAGACCTACAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32268
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046641 Essential Splice Site 1163 1364 25 30
Genomic Location (Zv9):
Chromosome 20 (position 3049589)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 3003451
GRCz11 20 3016291
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TAACATCATTCGAAAGGCTGTGCAGACTGCCATCGTCATATTGGTACCTG[G/A]TAAATGAAACCTTTATTTCTAAAACAATCTGGTAACTGCACATTCATACA
Long Flanking Sequence:
TTTAAAAAGCTGTGGACCAATCACAAGAGACCAAGCAGTTTGACCAATCAGAGCATGCTTTCTGAAAGGCGGGGTTTAGAAAGAAGGAGTCTTCTTCGACAGAATCAATTAGTTTAAGGCTCTTTGTACAGTGAGGGGATTTTTAATGTGTATTATGAAAAAACAAAGAACACAAAGGAAGCTGTATACTTTTAAAAAGGTACTAGAATACAAACACTTGAGTTAAATTGTAAGAAAAAATACTTTAGAAGTTCAAGTCTGTGGTATTTGGGCCTTTTTTATATATCTTGAATGTCTCCTAAAATGGATTTACATGAATCCATTGTCAAAAACCCCTAAGATTCATCATGAAAATAAAAAGTTCCATGTAGCCTAATGTTTTGTATTTCTCCAGGTGAATAAAGTCCTCCGCAACCACAACATCAAGCCACACTGGATGTTTGCCCTGGATAACATCATTCGAAAGGCTGTGCAGACTGCCATCGTCATATTGGTACCTG[G/A]TAAATGAAACCTTTATTTCTAAAACAATCTGGTAACTGCACATTCATACAGTTCCTGAAAGTGGAAATGGAAGTGCACATTGTTCATGCCTGCTCTTATTAAACACTTGATGACTGGTTGATTATTATAGTAGTCAATGACCTGTGCCACTGACATACCTGAAGTGTGCAGGAACTGTACTTGAAGGGGCTGTTCATAAAACTTGACATAAACAAACACATCACAACCGGTCTCTAACTGTATTATGACGACTTGACATTATGAAGACAACATCATTAATATTGTTATGAGGCGTTATAATTGTTGCTTGAATCTTTTTTCTGATTTGTCATTAAAATGTCTTATTAATTTGATTACTCTGTCAAATAATTTTGAAGAGAGTCATTAGTATTTAATCTAAATTCAGCTGTCGTTGAGGCTAGAAAAATATTAATGATGCTATTATAATATTCATGAAATATTTATAATAGCTTTATGACAATTATGTTGATGACAGATTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43368
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046641 Nonsense 1229 1364 26 30
Genomic Location (Zv9):
Chromosome 20 (position 3048635)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 3002497
GRCz11 20 3015337
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGGAGTGAGCACGCTTAGTTCAACAGTTTCCCACGAGTCGCAGAGCGCG[C/T]AGAGGTCTATCAGCATGGAGCTGGGTCGCATGAAGCTAGAAACCAAAAGG
Long Flanking Sequence:
TGAAATATTTATAATAGCTTTATGACAATTATGTTGATGACAGATTTATGACAAGTTTTGTTGTCTTGATAATGTTAAGCGTCATGTGAAAGACAAAACAGGTTGTGATGTACTTGTTAATGTCAAGTTGTCATAACAAACAATGTCATCTTTCCATTTAAAATTTCATAACTGACACTTAATAACAGTTGCCATAACATTTGCATTCATGTCATATCATGATCATAAAGTTTTCATGACACGTCTTAGGAACACCCCTTCAAGTAAAGTGTTACCGAACTGTTCCTTTCATGTGTTTGCCTTCAGAATTGCGTCCACACTTCACACTGGCATCAGAGAGTGACCCCGCCGAGCAGGAGGACATCGATGATGATGCAGTTCCTCAGGGAAACGCTGCACTAAAGGACATGGCACCAGCACTCGTTCATCACGACGACACTGTGGCCACGTCTGGAGTGAGCACGCTTAGTTCAACAGTTTCCCACGAGTCGCAGAGCGCG[C/T]AGAGGTCTATCAGCATGGAGCTGGGTCGCATGAAGCTAGAAACCAAAAGGCAAGTGTGTTTTATTTAGAATATATGTAATTGCAGCTGCTAGAGCGCCATCTGCTGTTTAAAAATTGTCCTAGAGCGCCGTCTGCTGTTAAAACTAGTCTAGAGCGCAATCTGCTGTTCTTAAAAACTAGCCTAGAGCGCCGTCTGCTGTTAAAAACTCTCCTAGAGCGCTGTCTGCTGTTAAAACTAGCCTAGAGTGCAGTCTGCTGTTAAAACTAGCCTAGAGTGCTGTCTGCTGTTAAAACTAGCCTAGAGTGCTGTCTGCTGTTAAAACTAGCCTAGAGTGCTGTCTGCTGTTAAAACTAGTCTAGAGCGCCATCTGCTGTTAAAACTAGCCTAGAGTGCCGTCTGCTGTTAAAACTAGCCTAGAGTGCTATCTGCTGTTAAACACTAGCCTAGAGCGCCTTCTGCTGTTAAAACTAGCCTAGAGTGCAGTCTGCTGTTAAACACT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17844
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046641 Nonsense 1247 1364 27 30
Genomic Location (Zv9):
Chromosome 20 (position 3047171)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 3001033
GRCz11 20 3013873
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AYATTTCGTCTGCTGTTTACATATGRCTGTGCTTRTRTGTTCTAGGTTGT[T/A]GGAGGAATTAGTAGARAAGGAGCGAGAATATCAGGCCATCCTGCAGCAGG
Long Flanking Sequence:
ACTATCCTAGAGTGCCGTCTGCTGGTAAACACTAGCCTAGAGCGCTGTCTGCTGTTAAAACTAGCCTAGAGCGCCGTCTGCTGTTAAAAACTAGCCTAGAGCGCCATCTGCTGTTAAACACTAGCCTAGAGCGCTGTCTGCTGTTAAAAACTAGCCTAGAGCGCCATCTGCTGTTAAACACTAGCCTAGAGTGCTGTCTGCTGTTAAAACTAGCCTAGAGCGCCGTCCGCTGTTAAACTCTAGCCTAGAGCACCGTCTGCTGTTAAAAACTATCCTAGAGCGCCGTCCGCTGTTAAACACTAGCCTAGAGTGTCGGCTGCTGTTAATAAACTATCCTAGAGCGACGTCTGCTGTCAAACACTATCCTAGAGCGCCGTCGGCTGTTAAACACTATCTTAGAGCGCCGTCCACAGAATCAATGCAGAATTATTCATGCGTTTCTTTTCACCAACATTTCGTCTGCTGTTTACATATGGCTGTGCTTATGTGTTCTAGGTTGT[T/A]GGAGGAATTAGTAGAAAAGGAGCGAGAATATCAGGCCATCCTGCAGCAGGTCCTAGAGGACAGAGAACAGGAGATCAAACTATTAAAGTGTCGAACCGGACCCATCGGTGAGGCTGACATTCAAATGATAAAACAGATTCTTCCTTCCATCTTGGTTTATTATTTAATTCTCCCAGTGTTCCATAGCACATGTTTCCTTATCATTGTGTGTAATACAAACTTGTTAAGCATTTGATTCTCATTGGCTAATGAGCAATATACGGTGTGGAGTTATTTTTCAGATAAATGCACCGCTAAAGTAGTTCCAGGCAGGTTTTGAGAGTTTGGGGTTTGAGTTTCACAGCGGAGGAGAAGTGCAGCGCCGTGTGTTTAAAAGTCTTCATCCATCTTTGTCCAAATATAGCAAATTTAGCAGCATACATACATGCGTCTGTTTATTATTTTCCTTTTTCTAGCACACGCCCAAACAAACCGGCATTTCACAGGGTTAATTTGAATAC
Associated Phenotype:
Not determined