Busch Lab

ZMP

LOC556262

Ensembl ID:
ENSDARG00000077349
Human Orthologue:
SORCS3
Human Description:
sortilin-related VPS10 domain containing receptor 3 [Source:HGNC Symbol;Acc:16699]
Mouse Orthologue:
Sorcs3
Mouse Description:
sortilin-related VPS10 domain containing receptor 3 Gene [Source:MGI Symbol;Acc:MGI:1913923]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa32145 Nonsense Available for shipment Available now
sa23046 Essential Splice Site Available for shipment Available now
sa36383 Nonsense Mutation detected in F1 DNA Not yet available
sa42908 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa32145
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114236 Nonsense 119 1018 4 27
Genomic Location (Zv9):
Chromosome 17 (position 20211126)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 20361137
GRCz11 17 20380973
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTCTGTTTCTCTTTTGGCTGTAGCTCTACAGCTCTGTGGACTTCGGGAAG[A/T]AGTGGATTCTTGTTCACGAGCGAGTAACTCCAGGGAGATTTTACTGGTAC
Long Flanking Sequence:
ATCAGAACGATGCTGAGCTATCTGTACGTCTGTCCGACCAATAAGAGAAAGGTGAGTGTCTTCAAAACGCATGAAAGATATGGACGTATAAAACTGTCAGAGAGCAAATATCCAGCTAATAAAACTCATGCTCCCACTCTTTCTTGTCCTCAGATCCTGATTTTATCCGATCCAGAGGTGGAGAGTAGTTTACTTATCAGTTCTGACGAAGGAGCCTCGTTTCAAAAGTTCAATATTAACTTCTACATCATGAGTCTTCTGTTTCACCCTACGCAGGAGAATTGGATACTGGCCTATAGCCACGATCAGAGGGTATACACACACACACAGACATGCTCGCACAGCCTCAAGAGGGCCTGCTGAACAATTAAAAGCAGATAATGTGGATAATTAAGTGCGAGCGAGATAATTACCTTTGTTGGCTGTAGTTAGGGATCTTAAAGTGAATGTGTCTGTTTCTCTTTTGGCTGTAGCTCTACAGCTCTGTGGACTTCGGGAAG[A/T]AGTGGATTCTTGTTCACGAGCGAGTAACTCCAGGGAGATTTTACTGGTACGACACACACATACATACACAATCTTTTTTTTTTTTACTGATCATCAATCTCATATAACACGCCTACAGTGCAATTTCACACTGAAAATTAATCTGACTGCAAGAATACACCTGCACACACACACTCACGCACAATCACATACTGAAAATTAATCCAATATTAAACCCACTCTCTACATCCACTGACACTGATAAACTTACACACACACACAAACACACACACACACTGTCTATGTCTCTTTCCCTTCTTTCTTTCTATCTATCTATCTCGCTGTCATGTCACTTCTCTCTCCCCTGTGCTTCATATTCCCGTACGTGTGGAATTTTGATCAGGTTTTATATTTTAATCCCATCAGTGTGAGTTTGTGTGTTTGTGTGTGGGGTGCATCAGAATAACTGGTTGCCTGTCACATGCTCGATGAGCTGTGGAGACAACACGTCTTCACCTCTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23046
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114236 Essential Splice Site 461 1018 13 27
Genomic Location (Zv9):
Chromosome 17 (position 20176298)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 20326309
GRCz11 17 20346145
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTGTCGACGGGGTTTTGATGACTCCAGAGACTGAGAATCGCATCATTAC[G/T]TAAGAATCATGTTCTCTGCCACACTGATCTCAATGGTCCAGAAGGGGTCA
Long Flanking Sequence:
CGGAAAGGAAGTAGAGTAAAGAGATGCGACACAAAAGCACAACGAAATGCAAAATAGATTGAATGTATAATGAGACTTCATCTGCATTTTACATGACTAATAATGATTAGAGGCTAATGTAAACACAACTGGGGTATGGTGAATAATTTTGTCCTGCTATTTTTCAACGAGCATATCTTAGATTTGATTTTAATGTAATTATGCAGATGCAGCCCACATTAAATGTTAATGCGGTGACTCCGCAACGACTTGTTTTTGTGCATCTGCAAAATATTCTCAGATGACTGAACAAATGCATCTTCTATTTTTATGTCTTTGTCAAATGTGCACAGTACAGTATATAAATCAGACGAGTGCTTTGCCAATGATATGATTTGTGTATGTGTGTGTAGGATTAGTCTGGATGAAGGCCGCCATTGGGACAAACTCAGCTTTTCGTCGACACCCTTATTTGTCGACGGGGTTTTGATGACTCCAGAGACTGAGAATCGCATCATTAC[G/T]TAAGAATCATGTTCTCTGCCACACTGATCTCAATGGTCCAGAAGGGGTCAGTAATGAACCTTCACCTACTGGGATCATTATTATCAGATTAAGTGTTTGCATTTGCATGTCTGGATGATGATCATTAGCACTGCTGTTTTACTAACACTTCCTTCTTATTAGTTCTTTATGGATTTTATGGCGCTAGAAGTCACTTTGTCAACTGTAAAGAATAAAAGTAAACAGATCCTGTTGTTTTCAAGCATCTCTGTCTGTCCTCGTAGATTCTTCGGGCACTTTAGTTACCACTCCGACTGGCAGCTGATAAAGATTGACTACAGCTCCCTGTTTGGGCGGAAATGCACAGACGGAGACTTTCAGACATGGCACCTCCATAACAAGGTTGTCACCTCACATTTTTCAGTAGCGCCTTACTGTTCGCTCTCAACAGCAATGCACTAATTCACTCACTCAACATTCAACATGAGTTTCTTTTGGCACTGAGTTCGCTAGTAATTAGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36383
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114236 Nonsense 718 1018 19 27
Genomic Location (Zv9):
Chromosome 17 (position 20167096)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 20317107
GRCz11 17 20336943
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTTAGGTCCCGTGGAGCGTATCTTTCTTTCGGCACCGGTGGTCGTGGCC[A/T]GAGGAAGAGAAGCCAACCTGACAGCAGTGTTGTGGCCCAGTCAGCCCAGG
Long Flanking Sequence:
TCAGTCCTTTATCTCTCTCTGTTATTGTTTTCTCTGCAGGGTGACTCACTGTCGACCAGTCTCCATGTGGACTTTGGAGATGGCATCTCGGTGTCATACTCCAACATAAGCCGCCTTGGTGACAGCATCACACACACATACAGGGTCGCTGGGATATTCAGGGTCAGCGCACGTGCTCAGAACAGCCAGGGCTCTGACAGCAGCTTGCTCTATCTGCACATCACCAGTACGTACATAAGCACACACTTATTCCAATTCTCCATAAGAATCCACCATACAAAAAGCTCTTTCCTGTCACAGCAAATTACCTCTATACCACTGACTGCACATCGAGACAATCTATTTCTGAAGCAGCTCTCAATAAACAACATAGGAAAAGAAATCGCTGCTCAATGTGATCGTTACTGACTTCATATTGCGTCTGATAAGATCTCACGTCCGATGTGTTGTTGTTAGGTCCCGTGGAGCGTATCTTTCTTTCGGCACCGGTGGTCGTGGCC[A/T]GAGGAAGAGAAGCCAACCTGACAGCAGTGTTGTGGCCCAGTCAGCCCAGGACGGCCACCTTCTACTGGTGGTTCAATAACAACACTGAGGTTCGAACATTTATACGCATGCGGCCCAGAGGCCCACATCTGTTAGCCAGCTATTCCAGTATTACTTCTGACCTCCAACAAAACAAGGGCTCGGCCAAAGATATTGTGCTTGCCAAGGCCAGAAAGGTAAACCTGTTATTAGGATGGATTGGAATTGGGGTCAAGTAAGTAAAAAGCTCGATGTTTGGGCCGGGGCGATACTGTGACACTGTGGGGTTTTTTTTTGCTTTGCAGTAAGAAACTTGCTGCCAAAATAAAAAGAATAACTGAATTTCAACTCTGTCAGAATAGCTTTTGTTGAATGACAGGCATAGCTGGGAAAATGCATTGGGGAAAGTGCTTCCAGCTCAGAGATCTGGCATATATTAAAAGCCCACATAGAATTTTAATTGTAGATTGCTTGTCAAAAGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42908
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114236 Essential Splice Site 747 1018 19 27
Genomic Location (Zv9):
Chromosome 17 (position 20167005)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 20317016
GRCz11 17 20336852
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCAGCCCAGGACGGCCACCTTCTACTGGTGGTTCAATAACAACACTGAGG[T/C]TCGAACATTTATACGCATGCGGCCCAGAGGCCCACATCTGTTAGCCAGCT
Long Flanking Sequence:
TGTCATACTCCAACATAAGCCGCCTTGGTGACAGCATCACACACACATACAGGGTCGCTGGGATATTCAGGGTCAGCGCACGTGCTCAGAACAGCCAGGGCTCTGACAGCAGCTTGCTCTATCTGCACATCACCAGTACGTACATAAGCACACACTTATTCCAATTCTCCATAAGAATCCACCATACAAAAAGCTCTTTCCTGTCACAGCAAATTACCTCTATACCACTGACTGCACATCGAGACAATCTATTTCTGAAGCAGCTCTCAATAAACAACATAGGAAAAGAAATCGCTGCTCAATGTGATCGTTACTGACTTCATATTGCGTCTGATAAGATCTCACGTCCGATGTGTTGTTGTTAGGTCCCGTGGAGCGTATCTTTCTTTCGGCACCGGTGGTCGTGGCCAGAGGAAGAGAAGCCAACCTGACAGCAGTGTTGTGGCCCAGTCAGCCCAGGACGGCCACCTTCTACTGGTGGTTCAATAACAACACTGAGG[T/C]TCGAACATTTATACGCATGCGGCCCAGAGGCCCACATCTGTTAGCCAGCTATTCCAGTATTACTTCTGACCTCCAACAAAACAAGGGCTCGGCCAAAGATATTGTGCTTGCCAAGGCCAGAAAGGTAAACCTGTTATTAGGATGGATTGGAATTGGGGTCAAGTAAGTAAAAAGCTCGATGTTTGGGCCGGGGCGATACTGTGACACTGTGGGGTTTTTTTTTGCTTTGCAGTAAGAAACTTGCTGCCAAAATAAAAAGAATAACTGAATTTCAACTCTGTCAGAATAGCTTTTGTTGAATGACAGGCATAGCTGGGAAAATGCATTGGGGAAAGTGCTTCCAGCTCAGAGATCTGGCATATATTAAAAGCCCACATAGAATTTTAATTGTAGATTGCTTGTCAAAAGGTAAGATTTGATTGGGCATTTAGCCTACTTTTCACAAGTTTGGTCACACTGTTTTTTTTTTTTTTAAATGACTTTTATTATGGCTGCTTAGC
Associated Phenotype:
Not determined