ZMP
ntrk1
Ensembl ID:
ZFIN ID:
Description:
Tyrosine-protein kinase receptor [Source:UniProtKB/TrEMBL;Acc:B3DGZ3]
Human Orthologue:
NTRK1
Human Description:
neurotrophic tyrosine kinase, receptor, type 1 [Source:HGNC Symbol;Acc:8031]
Mouse Orthologue:
Ntrk1
Mouse Description:
neurotrophic tyrosine kinase, receptor, type 1 Gene [Source:MGI Symbol;Acc:MGI:97383]
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa32109 | Essential Splice Site | Available for shipment | Available now |
| sa14939 | Essential Splice Site | Available for shipment | Available now |
| sa14955 | Nonsense | Available for shipment | Available now |
| sa36252 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa32109
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000027013 | None | None | 619 | None | 13 |
| ENSDART00000125908 | Essential Splice Site | 25 | 733 | 2 | 15 |
| ENSDART00000128068 | Essential Splice Site | 85 | 782 | 3 | 16 |
Genomic Location (Zv9):
Chromosome 16 (position 48906960)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 16 | 45876181 |
| GRCz11 | 16 | 45842897 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATTTTGGGTGGACACACAAAAGAAAGGTTAATGCTTTTCTTGTTTGTTTC[A/T]GGACGATCACAGATTGTGGGTTGGTGTACATCTCTGAAAATGCCTTTCAG
Long Flanking Sequence:
AATGTTTATCAATAAACTCATTTTAAGAACTGTTCACTGAAAAGTTCTCTGAGAAAACAAAAAATGATTGTTCTGAGGCATTGCTGATGAAAAACTCGTTTAATATCAACCTGTTTTTCTTTTAGCTACATAGAGAGTCAACCCAACCTGGAGAACATCACAGATGTAGACCTCGCCAACTACAGAGAACTGAAGAATCTGTAAGTATGACAGCCTACAAAAGATTTTCAAGTGGTTTAAGAGGTAAATGGTACTTACAAACATAGATATAGAATTAGATATACGTTTGGGGACAGGTGATTTTAAGTCAAGTTATATTCCTGTGATGCAAAGCTGAATTTTTAGCATCATTCCTACAGTCATTAGTGTCAAAGAATCCTTCAGAAATCATTCCTTATATACTGATATGCTGCTTTTAGAAGATTTCTGATTGTTATTGTGTTGCCTAATATTTTGGGTGGACACACAAAAGAAAGGTTAATGCTTTTCTTGTTTGTTTC[A/T]GGACGATCACAGATTGTGGGTTGGTGTACATCTCTGAAAATGCCTTTCAGCATAACTTCAAGCTGCAGTATGTGTGAGTGTTCTTTACATATAATACTGGCCTTCCCACAATACACTTGGGTCTCCAGGCTTGTACCTGTCAATCACTTCAAATCCTCTTCCATTCTGATGAGTGAAGCTGCATTATTGGTCTCCGGCGGTAAAAACCCAAGACACATTTAAAGTTATTCAACCAAAATATGAAAACACATTTCCACACCACATTTCCAGAAATCATTTGATGTCCTCCTTCCCGCTAAATCAAGAGGAAATTGGAAGAAATGTGTTGCTCATTATAATCATGTGATCTTAGTCCTTGAGGACAATCTGAAAATGTTTTTGGGTGGGAAACTTCCTAAAATCAGCTTGGTTAATGAGTATTAATGATGTGACATGAGATCCAGTAGCTTATTGTAACCATATTACAGAGGCTCTATCTGTCCATATATCTATTTATTTGA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa14939
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000027013 | Essential Splice Site | 52 | 619 | 2 | 13 |
| ENSDART00000125908 | Essential Splice Site | 170 | 733 | 5 | 15 |
| ENSDART00000128068 | Essential Splice Site | 230 | 782 | 6 | 16 |
Genomic Location (Zv9):
Chromosome 16 (position 48896625)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 16 | 45865846 |
| GRCz11 | 16 | 45832562 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CGACGATCCACTGGAGAACTGAGCRSCTTCGGTCCRGCTGGAYCCTRGAG[G/A]TACATGAGACATCTATGGAAACTGACSATATAAGTATATCACTGGATCAG
Long Flanking Sequence:
GTGTATATCTATATATAATTATTTTTTTCAGAAATCATCCAAATTTGCTGATTTACAGCTAAAATGTTTTTATTACCAATATTTTAAACTGTTATTGGTGGAAATCAAGACCTTTTCAAGATTTGTGGTGTTTAAAAGCTTAAAAAGACAACGTGAATTGGAAATAGCAAGCTTTTGTTACATTCTAAATGTTTTACTGCCACTTTTGATCAGTTTAAAATGCATCTGTGTGAAATTAAAGTGTTTATTTGAAGCAAAATGTTGCCACATTTTATACGCTCACACATTTCAGATGATCATGTTGTTCTTCTCTTTCCCCTATCACTTCCATTTTCAAAATGTTTCTGTGATCTGCAGGTGTTCCTGAGGTCATGATTGACCCACCGACAGTGACCACTCAAGAAGGTGGAAATTTGACATTTACCTGCAGAGTGACTGGAGTTCCCACACCGACGATCCACTGGAGAACTGAGCAGCTTCGGTCCAGCTGGACCCTGGAG[G/A]TACATGAGACATCTATGGAAACTGACCATATAAGTATATCACTGGATCAGAATTACTTGTTGGCACTGGCAACATAAAACACAGGCAACACAATGATTAGATTAGATTCAACTTTATTGTCATTACACATCTACAAATACAAGGTAACAGTATGCAGTTTAGCTCTAACCAGGAGTGCAAAAGCAGCAAGTTCAGGATATAGGTATAATTTATAAGTGCACTTATAGAAAACTATGGGTAAAATGTTCAGATGGATGTACTATAAACTTAATATACAAATAAACCGGTTGTATGTGATCTATGTAATGATCTGTGATCTAATTAACTATGTAATGACAATAAACAAAGTACCAGTAAAAGCAAATCTGGTAAAGTTTCTGCTGAAGACGCTCCCCTTTATGAGTGGAACAAATAACATGTATTTGTGTGTGTTTCTATAAATGCAAATGAGCTACTGCTCCCGCCCACCTTTTCAGAAGAGGGCGGAGCCTTTATAGATT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa14955
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000027013 | Nonsense | 58 | 619 | 3 | 13 |
| ENSDART00000125908 | Nonsense | 176 | 733 | 6 | 15 |
| ENSDART00000128068 | Nonsense | 236 | 782 | 7 | 16 |
Genomic Location (Zv9):
Chromosome 16 (position 48895098)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 16 | 45864319 |
| GRCz11 | 16 | 45831035 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCTCAGACAGTTAAACCTGTACTGTTGTCCACAGCAWGGAATCTKGGGAT[C/A]AACCCTGGAGGTGRTTCTGCACATGAGRAAYGTGTCTTCTGCTGACAACC
Long Flanking Sequence:
AGGGAATCGTTTTCATTCTAAAATGCCATTTTAAAACTAAGACGTATTAGTGTAAACGAGGCCTGAGTGTGTTTTTGACGAGTGATTTGCTGCTGCGACAGTTGCGGGGTGGAAGATTGCGATGCCGGCTCAGCGTTGTGATGTCTATCGACCCAACCCTATTATATATATAGGCATAGTTCATAAATAGTTTCTGCATATATAGCCATATATGAACACCAATATAAAACTATAACTAATATATTGTATGTTTGGTTGATATGGTTGGAAAAAGGGGTCCGCTTTTCTATATGTCTACAAATATGTTGCGTATATGACATATGTTAAATACTGTTCGTGAAAGCCGAATATCCACTATTTTGTCATATATGTAAATTAAATAAATCAGATTTCTATGTAGTGAGCATAACTGGCATAACTTTTAATCAAATGTTGTTCAGTTGTTTACATGCTCAGACAGTTAAACCTGTACTGTTGTCCACAGCAAGGAATCTGGGGAT[C/A]AACCCTGGAGGTGGTTCTGCACATGAGAAATGTGTCTTCTGCTGACAACCTGCACAACCTCACCTGTGAAGCGGAGAATCGCGCTGGAATGGGAGATGCTGTGGTGCAGCTGGACATTGAATGTAGGCACTGACATCTTTCTGCTCTTTATATTTCGTCCATTTTTTCCCTCTTTAATGCTCTCGCCTTTCTGACAAAAAAAAAAAAAACTAAATATTTTGCATAAATGTTCGGCAGCACAATTGAATTCTGATGGAAACTTGTTTCTGCATCTGAATACAAATAAAAAAAGTAAAGCTGCGAGATGTGAAATTGCTAAGATTTTGATTTATCAAGTGGAAATCTCTTATTTAACTTTTTTATTTTAGGATTCTGAATATCAAATAAGCTTTGGCTGTTTCTATAGCAGACCTACATATGTGATTACTGAAACCAAATGTTGAACTGACTAACAAAGCCAAAATAAGCCTAAAACAAATATGTACTTATATATATATATA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa36252
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000027013 | Essential Splice Site | 209 | 619 | 4 | 13 |
| ENSDART00000125908 | Essential Splice Site | 327 | 733 | 7 | 15 |
| ENSDART00000128068 | Essential Splice Site | 387 | 782 | 8 | 16 |
Genomic Location (Zv9):
Chromosome 16 (position 48885930)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 16 | 45855151 |
| GRCz11 | 16 | 45821867 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTTCATGGACAATCCTTTTGATCCCTCTGACCCGGAGGGCATCATCCCTG[G/A]TGAGGGCACTTCATCTAAATTATATTACACCAACTGTGTGGTGCATTGAG
Long Flanking Sequence:
AAAAATATATTTTAAATATACTTCAAATACTGTAAAAAAAGCCTTGTTCTGTTAAACATCATTTAGGAAATATTTAATAAAAGAAATCCACAGGAGAGCTAATCATTGTGACTTCAACTGTGCGCGTCTTACTGCACACACATGTAATGTCTCTGTCTGTGTTCCAGTTCCAGTGCGGATCATATATCTCAAGAACCCAGAATCTCAACATCACTGGTGTTTCCCGTTCGCCGTAGACAGCAATCCTCCCGCCAGCATCAAATGGCTGTACAACAACATGCCTCTCACTGAGACCCGCTATGCCTACACTGAACTCATCAGAGACGTGTACGACGGCTCACAGCAACACGGCTGTCTGTTCCTTAACAAACCCACTCATCTCAACAACGGCAACTACACAATCATCGTGAAGAACAAACTGGGCAGAGACCAGAGAACAGTCCGAGCCAAGTTCATGGACAATCCTTTTGATCCCTCTGACCCGGAGGGCATCATCCCTG[G/A]TGAGGGCACTTCATCTAAATTATATTACACCAACTGTGTGGTGCATTGAGTAATTGTTTGTTGTATTCTCTCTCTTTTCACATGCCAGTGCTCAATGACGACCCAAGTAAGTTACTCTATATAAGGTTAAATGTCTAAATGTTGTTAAAAAGGGTAGTTCACCCAAACACCAAAAACACTGTCAACATTTATTCACCCTTAATGAGTTTTTTCTTCTTTGGAATAGAAAAGAGGATATTAAGTTGGAAACCTGTAACTATTCACTTTCATAATATTTGTTTTTCCTATTATGGAAGTCAGTAGTATTAAGCAAGTTTTCAGCATTCAGAAAATATTATTTAGTGTTTAACAGAGGAAAGAAACTCAAAGGGCTCTATCATACACTCGGCACAATAAGGCTCAGGATGTGTTTGGTGCGATTTTTTGCTATTTTCAGACCAGCGCAAAGTAATTTTATCATTTTGTGCCACGTTGTTTCAATAGCAAATTAATTTGCACCA
Associated Phenotype:
Not determined