ZMP
eif3ea
Ensembl ID:
ZFIN ID:
Description:
Eukaryotic translation initiation factor 3 subunit E-A [Source:UniProtKB/Swiss-Prot;Acc:Q6DRI1]
Human Orthologue:
EIF3E
Human Description:
eukaryotic translation initiation factor 3, subunit E [Source:HGNC Symbol;Acc:3277]
Mouse Orthologue:
Eif3e
Mouse Description:
eukaryotic translation initiation factor 3, subunit E Gene [Source:MGI Symbol;Acc:MGI:99257]
Alleles
There are 5 alleles of this gene:
Allele Name | Consequence | Status | Availability |
---|---|---|---|
sa45584 | Nonsense | Mutation detected in F1 DNA | Not yet available |
sa22915 | Essential Splice Site | Available for shipment | Available now |
sa4677 | Nonsense | F2 line generated | Not yet available |
sa32103 | Essential Splice Site | Available for shipment | Available now |
Mutation Details
Allele Name:
sa45584
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000126705 | Nonsense | 84 | 446 | 3 | 13 |
ENSDART00000140684 | Nonsense | 84 | 109 | 3 | 7 |
ENSDART00000144651 | None | None | 157 | None | 5 |
The following transcripts of ENSDARG00000090697 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 16 (position 41291577)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 16 | 38676377 |
GRCz11 | 16 | 38626409 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTTTGCAGCTCTTCGAGAGAAGAGAACTACAGTAGTGGCTCAACTCAAA[C/T]AACTCCAATCTGAAACGGAGCCAATTGTGAAGGTGTTTGAGGACCCAGAG
Long Flanking Sequence:
AATTTTCATTTTTAGGTCCCGCAATGCGTTTAATTTTCTCTCACACTGACACACACACACACACACACACACACACACACACACACACACACACACACACACACACATATGAGTAGACAAACAGGTGTTGATCAATTTTTCCTGCCAGTCAAAACCTACAAGTAGAAAAAGTCAAATATTTTTGATAAACTTATTAAAGTATTCTCATATTCTTCGTGAATGTGCTTATCTTGTTTCTATTATCATTTTCTAGATCTACAATGAGCACGAGCTCCTCCATGGAAAGCTGGATCTCCTCAGTGACACCAACATGGTGGACTTTGCCATGGATGTATACAGGAATTTATTTCCTGACAAAGAAATACCCAACTGTAAGTGTTTTTACTTTTAATTGAAGCTTAATGTGATATGACTATGAGATTGTTAGTATTATTACTTATTTATATGTCTTCTTTGCAGCTCTTCGAGAGAAGAGAACTACAGTAGTGGCTCAACTCAAA[C/T]AACTCCAATCTGAAACGGAGCCAATTGTGAAGGTGTTTGAGGACCCAGAGACCACGAGGCAAATGCAGTCCACGAGGTAAATATTGAAATGACACGTACACAAACAGCTGATTTACATGAGTAAATTGCTATAGCCTGAAAGCAAAAATATTTTTATCAAAATTAGAGGAAATTGTTGTATTGTTTTTGTCATATTATTATTACTTCTTGTTATTAACATAAATCATTCATACATTTTCTTTTCGGCTTAGTCCCTTTATTAATCCAGGGTCGCCACAGCGGAATGAACCGCCAACTTATTTAGCACGTTTTTACGCAGAGGATACCCTTCCAGCCGCAACCCATCTCTGGAAAACATCCACACACACTCATTCACACTCGTACACTCCGGACAATTTAGCTTACCCAATTCACCTGTACAACATGTTTTTAGACTGTGGGGGAAACCTGAGCACCCGGAGGATACCCAGGCGAATGCAGGGAGAACATGCAAACTCCAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa22915
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000126705 | Essential Splice Site | 200 | 446 | 6 | 13 |
ENSDART00000140684 | Essential Splice Site | None | 109 | 5 | 7 |
ENSDART00000144651 | Essential Splice Site | 58 | 157 | 2 | 5 |
The following transcripts of ENSDARG00000090697 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 16 (position 41258448)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 16 | 38643248 |
GRCz11 | 16 | 38593280 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGCTGCCATGGAAGACCTGACCCGCCTGAGGGAGACTATCGATAACAAT[G/T]TAATGCCCCGCCACTCAGAATTCAATACCACATTCGGATTCCCTTACATA
Long Flanking Sequence:
TATTTTCTAAAATTTCATGGTTCTTTGCAGAACAAAAGTTATATATATATATATGAATTCAACTATTCTTTCAAGATTTATTTCTTTTTCCCCTGCAAGACCAATTCCCGAAGATGACATAATTTAATCCATTTATCCACTTTAAATAAATAAAGAAGTTACTCTGGCGATCAGCGTTGCCAAGAAAGCTCAAATTTTAGCTGTGGGAAATGGCAGATGTCAGAAATACAATATTTCTAAAGTGGAAAAGCACCAAGAGTGCCATCCAGCCAGTATAATTTGCTGCTGTTTTTATGGGAAGTGAGTTGATTTCATTGTCTTTGTTTGTTTACAGTGGGTCAATGTATTTCTCTTGTGTTTGTGTGTTTGTGCAGGTCCCGGCCACAGACAGAAACGCGCTGAACTCTCTGTGGGGCAAACTGGCTTCAGAGATCCTGATGCAGAACTGGGAAGCTGCCATGGAAGACCTGACCCGCCTGAGGGAGACTATCGATAACAAT[G/T]TAATGCCCCGCCACTCAGAATTCAATACCACATTCGGATTCCCTTACATAGGCCATAATATTGACCGCTTTGCGTTTGAGCACAGCACCACTCGCTGCTGTTGCCGTTCCTTCTCTCTTCCATCTCCTGATTCCTTCTCACCGCAGCTCACAAGTCAAGCAAAACCTTAATTGCTGTGTTCTGTCGGCACAGCTTGATTTTTAATTGGAGGAATTGAGCTGGGAAAGGAGGGTTTGGTTTGGGGCGAAGTATGAGTAAATAAAAAATTAAAGTCTTAGGACATTGTAAAATTCTATTCTGAACTTTGATTTGAACTGAGTCTGGAAGGCAACCGAAGCCAAATGTTTGTTTTTCGGAGTCAGAAGTTCATCTTGCTGTAGTCACGATCAAAACAAATCACCTTTTAAAGGGGAGTTCACTCCAAAAGCAATATTTTATGATTATTTACCTACTCTCGTGTTATTTCTTGTGTATTTTTCTTACTTGTACCCTTTTTCAAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa4677
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000126705 | Nonsense | 251 | 446 | 8 | 13 |
ENSDART00000140684 | None | None | 109 | 7 | 7 |
ENSDART00000144651 | Nonsense | 98 | 157 | 4 | 5 |
The following transcripts of ENSDARG00000090697 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 16 (position 41248050)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 16 | 38632850 |
GRCz11 | 16 | 38582882 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTTGTTGTTTGTTTTGTTTACAGGTACCTCAATGCTATTCAGACCATGTG[T/A]CCACACATACTGCGCTATCTGACCACAGCCGTCATCACCAACAAGGACGT
Long Flanking Sequence:
CAATCCCTGTATTTATATGAAATTCATGATTTATGCAAAATAATGTCTTGGTTAGAAGTTTTGTCTTGTTTCTAGTTCAAATATCCACATTTCAAGGTCAAAATAAGATTATTTTACTTACCCCTCTGGCAGATAATTTTGCTTGTTTTAAGGATTAACTCTTGATTTTTGACTTTTTACTTGAATTTTGACTTATTTCTGCTGACGGTTAAAACAAAACAGTATTTCACTTGCTCTAAGAATCTACCAAGAAATTTTAGGATGTCTGCAACTACTGATGGCTAAGTTTTTATATAATCTTAAGCATACGCGTCTTCATTCAGGATATTTGCATTAAAGTATTGAATTTTTTTTTTTTTTTTGTTGGAGCCTGCTTTGTAACTGTTTACATTAATCTTTGTACAATAAATGTTTATTACCTGTTTATTACCAGACACTTGACTTGTGGTTGTTGTTGTTTGTTTTGTTTACAGGTACCTCAATGCTATTCAGACCATGTG[T/A]CCACACATACTGCGCTATCTGACCACAGCCGTCATCACCAACAAGGACGTCCGCAAGCGTAGGCAGGTGCTGAAGGATCTGGTGAAAGTCATCCAGCAGGTATCAGACACCACTAGGCTTCCTTATTTGTGCATTTCTATCTCCTTCAGTCACTTTCTATTCATTATTGAATATACTATATTATCTAATATAATATACTATATTTAATATCTAATATAATATACTATATTTATTATACAGCATATTTTAATTGTTTTAAATTTGATAATTGTTTTTTTATATAACATTTAATAAAATGTAGTGATGCAATAAAGTAGTGATGCACAATAAATTGATATAATGTATATGAATAAAAATTTACTTATGTATTTTAATTTAAAAAGATAAATATTTTTACTTATGTGATGTACCATAAAATACATCTTTTATAAACTTTTCAAATAAAAAGTATAGCGATGAACCGTTAAAAAAACAACAAATTCATCCACATCAAACAGCAG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa32103
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000126705 | Essential Splice Site | 389 | 446 | 11 | 13 |
ENSDART00000140684 | None | None | 109 | None | 7 |
ENSDART00000144651 | None | None | 157 | None | 5 |
The following transcripts of ENSDARG00000090697 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 16 (position 41226435)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 16 | 38611235 |
GRCz11 | 16 | 38561267 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAACCTCATTCGTAATGCCAGGCTGGATGCCAAAATCGACTCCAAACTGG[T/C]GAGAGTCTCTCATATTTTATTTCGCTCTTGTTTCCCTGCCTCCCTCCTCA
Long Flanking Sequence:
TTTAAAATGCTTTTAAAAAACAGTAAAACTCATGCAGTGAGTGTTTTATTCCTGTCCTAAAGTTTGTTTCATCACTACCTTGACCTCAAACTCACGACGGCACGGTGATGTAATTCTACCCCGTTTTTATGGGTTTCTTAGTGCGATTAGAATCACAGACTTGATTACATAATGCAAGGCATTTGTCACTCTTGAACAGACGTCTAAATGCTGAGGTATGACAGTAAACCCATTATCATCCAGCACTTTCGATCAGCACTTTAAACCTGCACACACACACACACACAGCCACCGCAAGCTTGTTATATACCTCACAATTTTAACGTAATGCCATCAGAGTATATAATGTTCTCCTTTTACCTAAGTTTGTCCTAATGGACTGTGTTTGCCTCGCAGTATGCTGGCCGATAAGCTGAATATGACTCCTGAGGAGGCAGAAAGATGGATCGTCAACCTCATTCGTAATGCCAGGCTGGATGCCAAAATCGACTCCAAACTGG[T/C]GAGAGTCTCTCATATTTTATTTCGCTCTTGTTTCCCTGCCTCCCTCCTCAAGTAGCGGCCAATTGATAGATGCTGCGTTAGTGTCCTTTAATTAGTAGGAAAATCAAATTCAGGCTCTTTTGTGCAGGGATAATGTTCTGCTTTAATACATAAAGGAGAGGCAATCAATTACGTCAGTAATTCTGCCCAGTGCCTGCTTTCTCACCATATCCTTTCTCGAGGGTTAGAGGAATACTGTCATTATAGTTCTGAAGGAGGGTCATTCGTAATGTGGAGACGTACTTTTTGGTCAAAATTAAGTTTATTATAAAGAAATCCTATGTGTGGAACATTCTGTTTTCATTAATATGTCAATTGTTTGCCCACCTTAGGCATTGCAATAGTTCATGAAGTGTATAAAAACTCAATTAAAGGTCCCATGAAAATAAAATAAATGTTTTAGATGTTTGTTTTTATAGATCTATACACAGTAGATATGACATACGAACCCTGAGTATACG
Associated Phenotype:
Not determined