Busch Lab

ZMP

gna11

Ensembl ID:
ENSDARG00000010002
ZFIN ID:
ZDB-GENE-050208-597
Description:
guanine nucleotide binding protein (G protein), alpha 11 (Gq class) [Source:RefSeq peptide;Acc:NP_0
Human Orthologue:
GNA11
Human Description:
guanine nucleotide binding protein (G protein), alpha 11 (Gq class) [Source:HGNC Symbol;Acc:4379]
Mouse Orthologue:
Gna11
Mouse Description:
guanine nucleotide binding protein, alpha 11 Gene [Source:MGI Symbol;Acc:MGI:95766]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa5692 Essential Splice Site F2 line generated Not yet available
sa3183 Essential Splice Site F2 line generated Not yet available
sa5691 Nonsense F2 line generated Not yet available
sa3194 Nonsense F2 line generated Not yet available
sa37508 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa5692
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000105566 Essential Splice Site 107 359 2 7
ENSDART00000136795 Essential Splice Site 105 400 2 8
ENSDART00000105566 Essential Splice Site 107 359 None 7
ENSDART00000136795 Essential Splice Site 105 400 None 8
Genomic Location (Zv9):
Chromosome 22 (position 22191089)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 21844337
GRCz11 22 21869315
KASP Assay ID:
554-3147.1 (used for ordering genotyping assays)
KASP Sequence:
CCGCGCCACCGAGCACCTCAAGATCCCATTCAGATTCGAAGACAACAAGG[T/A]GAGCGCTGCACACTTACAATCCCAGCCCTTATCATCGCTTTGATGCGCGT
Long Flanking Sequence:
CTTGCAGATCAGCTGGACGCTTTATGAACTGAATTTTAATGAATATTTTGCGCAAAAAATGTGGCGTTTAACTGCTAAAACATTCTCCAATAAACTTTTGTTTATAAATGTTTTAGTTTATGTAATCTTAAAGTTTTGTACAATAAAGAAAATCTGTAGTAGTGTTGCTACCTTTAAGGTTGCAAAGGCTTTTAATGCATCTATTTTTAATTTGGATTTATTTAATTTGAAAAACTATTTATTAACTAACGACAATATCCAAACATCAGATAATAACCCTCTTTTTTAACACCTGTGTCTGTTTTGCTCCTCAGGGACAGGCGAGAGCGGCAAGAGTACGTTCATCAAACAGATGCGCATCATTCACGGGACGGGCTACACCGACGAGGACAAGCGCGGTTACACCAAACTCGTCTACCAGAACATCTTCACCTCCATGCAGGCAATGATCCGCGCCACCGAGCACCTCAAGATCCCATTCAGATTCGAAGACAACAAGG[T/A]GAGCGCTGCACACTTACAATCCCAGCCCTTATCATCGCTTTGATGCGCGTCAAGATGCAAATCAAACCCAGATAGGCCATAAACGTGGCTATAAAAAGCACTACAAGGCTCGCCTGTAAATTTTATTGCTGTCACACCACGGTGAGCTGTCTTTTGTACAGGATTATGGTTAATTATTCCCATGTTTAGTTTTTTTTTGCTTTTAAAGAATCAGTTAATATTTCCTAAAGAAGATCCTTAAAGTTTAACTCCACACGACTTGTGGCCTAGTTGGTTGCGAACTGCTCTGGAAGTCATTAGTATTACACAGCTGTCAAGTCGTAAAATGGGTTGTGTTTTTATTGTGTCTTTATCTGCAGAAAAACGCTCTGCTGGTGCGAGAGGTCGATGTCGAGAAGGTTTGCTCTTTTGAACAGCCCTATGTTGCTGCAATTAATAAGCTCTGGATGGATCCGGGCATCCAGGAAGCATACGACCGCAGGCGAGAGTACCAGCTCTCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa3183
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000105566 Essential Splice Site 107 359 2 7
ENSDART00000136795 Essential Splice Site 105 400 2 8
ENSDART00000105566 Essential Splice Site 107 359 None 7
ENSDART00000136795 Essential Splice Site 105 400 None 8
Genomic Location (Zv9):
Chromosome 22 (position 22191089)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 21844337
GRCz11 22 21869315
KASP Assay ID:
554-3147.1 (used for ordering genotyping assays)
KASP Sequence:
CCGCGCCACCGAGCACCTCAAGATCCCATTCAGATTCGAAGACAACAAGG[T/A]GAGCGCTGCACACTTACAATCCCAGCCCTTATCATCGCTTTGATGCGCGT
Long Flanking Sequence:
CTTGCAGATCAGCTGGACGCTTTATGAACTGAATTTTAATGAATATTTTGCGCAAAAAATGTGGCGTTTAACTGCTAAAACATTCTCCAATAAACTTTTGTTTATAAATGTTTTAGTTTATGTAATCTTAAAGTTTTGTACAATAAAGAAAATCTGTAGTAGTGTTGCTACCTTTAAGGTTGCAAAGGCTTTTAATGCATCTATTTTTAATTTGGATTTATTTAATTTGAAAAACTATTTATTAACTAACGACAATATCCAAACATCAGATAATAACCCTCTTTTTTAACACCTGTGTCTGTTTTGCTCCTCAGGGACAGGCGAGAGCGGCAAGAGTACGTTCATCAAACAGATGCGCATCATTCACGGGACGGGCTACACCGACGAGGACAAGCGCGGTTACACCAAACTCGTCTACCAGAACATCTTCACCTCCATGCAGGCAATGATCCGCGCCACCGAGCACCTCAAGATCCCATTCAGATTCGAAGACAACAAGG[T/A]GAGCGCTGCACACTTACAATCCCAGCCCTTATCATCGCTTTGATGCGCGTCAAGATGCAAATCAAACCCAGATAGGCCATAAACGTGGCTATAAAAAGCACTACAAGGCTCGCCTGTAAATTTTATTGCTGTCACACCACGGTGAGCTGTCTTTTGTACAGGATTATGGTTAATTATTCCCATGTTTAGTTTTTTTTTGCTTTTAAAGAATCAGTTAATATTTCCTAAAGAAGATCCTTAAAGTTTAACTCCACACGACTTGTGGCCTAGTTGGTTGCGAACTGCTCTGGAAGTCATTAGTATTACACAGCTGTCAAGTCGTAAAATGGGTTGTGTTTTTATTGTGTCTTTATCTGCAGAAAAACGCTCTGCTGGTGCGAGAGGTCGATGTCGAGAAGGTTTGCTCTTTTGAACAGCCCTATGTTGCTGCAATTAATAAGCTCTGGATGGATCCGGGCATCCAGGAAGCATACGACCGCAGGCGAGAGTACCAGCTCTCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa5691
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000105566 Nonsense 128 359 3 7
ENSDART00000136795 Nonsense 126 400 3 8
ENSDART00000105566 Nonsense 128 359 3 7
ENSDART00000136795 Nonsense 126 400 3 8
Genomic Location (Zv9):
Chromosome 22 (position 22190667)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 21843915
GRCz11 22 21868893
KASP Assay ID:
554-3403.1 (used for ordering genotyping assays)
KASP Sequence:
CTGGTGCGAGAGGTCGATGTCGAGAAGGTTTGCTCTTTTGAACAGCCCTA[T/A]GTTGCTGCAATTAATAAGCTCTGGATGGATCCGGGCATCCAGGAAGCATA
Long Flanking Sequence:
ACATCTTCACCTCCATGCAGGCAATGATCCGCGCCACCGAGCACCTCAAGATCCCATTCAGATTCGAAGACAACAAGGTGAGCGCTGCACACTTACAATCCCAGCCCTTATCATCGCTTTGATGCGCGTCAAGATGCAAATCAAACCCAGATAGGCCATAAACGTGGCTATAAAAAGCACTACAAGGCTCGCCTGTAAATTTTATTGCTGTCACACCACGGTGAGCTGTCTTTTGTACAGGATTATGGTTAATTATTCCCATGTTTAGTTTTTTTTTGCTTTTAAAGAATCAGTTAATATTTCCTAAAGAAGATCCTTAAAGTTTAACTCCACACGACTTGTGGCCTAGTTGGTTGCGAACTGCTCTGGAAGTCATTAGTATTACACAGCTGTCAAGTCGTAAAATGGGTTGTGTTTTTATTGTGTCTTTATCTGCAGAAAAACGCTCTGCTGGTGCGAGAGGTCGATGTCGAGAAGGTTTGCTCTTTTGAACAGCCCTA[T/A]GTTGCTGCAATTAATAAGCTCTGGATGGATCCGGGCATCCAGGAAGCATACGACCGCAGGCGAGAGTACCAGCTCTCTGACTCCACTAAATAGTAAGTGTGTGTGTGTGTGTGTCGTCATTTGCTGCTTTTAGGTTTATTGCTTTTAAAATGAGTCTTTGAATCTCTTTTTGAGGTCAGTTTATGTGTCTGAAAGCATGTCATAGATGGGCAAGTACTGTTTTAAAAGGACATTTCACCCAAAAATTACCTAATTATATAATTAGTCTAAACTTTCAGTTCATTAAAGATTTATAAAGTGATAACTGGATCAAACACAAGTCTTTGAGGGTCAAACAATGAAACAAAGTTGCCTTAAATGGCAAATATTCATTTTTGGGCCACCTATAACTTAAAAGGGATAGTTCACCCAAAAATTAAAAAAAAACTCTATTCACCATCAAGTGGTTGCAAATCTTTGTGTTTTGTTGACAAAAGAAGATATTTTGAAGCATGTTGAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa3194
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000105566 Nonsense 128 359 3 7
ENSDART00000136795 Nonsense 126 400 3 8
ENSDART00000105566 Nonsense 128 359 3 7
ENSDART00000136795 Nonsense 126 400 3 8
Genomic Location (Zv9):
Chromosome 22 (position 22190667)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 21843915
GRCz11 22 21868893
KASP Assay ID:
554-3403.1 (used for ordering genotyping assays)
KASP Sequence:
CTGGTGCGAGAGGTCGATGTCGAGAAGGTTTGCTCTTTTGAACAGCCCTA[T/A]GTTGCTGCAATTAATAAGCTCTGGATGGATCCGGGCATCCAGGAAGCATA
Long Flanking Sequence:
ACATCTTCACCTCCATGCAGGCAATGATCCGCGCCACCGAGCACCTCAAGATCCCATTCAGATTCGAAGACAACAAGGTGAGCGCTGCACACTTACAATCCCAGCCCTTATCATCGCTTTGATGCGCGTCAAGATGCAAATCAAACCCAGATAGGCCATAAACGTGGCTATAAAAAGCACTACAAGGCTCGCCTGTAAATTTTATTGCTGTCACACCACGGTGAGCTGTCTTTTGTACAGGATTATGGTTAATTATTCCCATGTTTAGTTTTTTTTTGCTTTTAAAGAATCAGTTAATATTTCCTAAAGAAGATCCTTAAAGTTTAACTCCACACGACTTGTGGCCTAGTTGGTTGCGAACTGCTCTGGAAGTCATTAGTATTACACAGCTGTCAAGTCGTAAAATGGGTTGTGTTTTTATTGTGTCTTTATCTGCAGAAAAACGCTCTGCTGGTGCGAGAGGTCGATGTCGAGAAGGTTTGCTCTTTTGAACAGCCCTA[T/A]GTTGCTGCAATTAATAAGCTCTGGATGGATCCGGGCATCCAGGAAGCATACGACCGCAGGCGAGAGTACCAGCTCTCTGACTCCACTAAATAGTAAGTGTGTGTGTGTGTGTGTCGTCATTTGCTGCTTTTAGGTTTATTGCTTTTAAAATGAGTCTTTGAATCTCTTTTTGAGGTCAGTTTATGTGTCTGAAAGCATGTCATAGATGGGCAAGTACTGTTTTAAAAGGACATTTCACCCAAAAATTACCTAATTATATAATTAGTCTAAACTTTCAGTTCATTAAAGATTTATAAAGTGATAACTGGATCAAACACAAGTCTTTGAGGGTCAAACAATGAAACAAAGTTGCCTTAAATGGCAAATATTCATTTTTGGGCCACCTATAACTTAAAAGGGATAGTTCACCCAAAAATTAAAAAAAAACTCTATTCACCATCAAGTGGTTGCAAATCTTTGTGTTTTGTTGACAAAAGAAGATATTTTGAAGCATGTTGAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37508
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000105566 Essential Splice Site 159 359 3 7
ENSDART00000136795 Essential Splice Site 157 400 3 8
Genomic Location (Zv9):
Chromosome 22 (position 22190573)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 21843821
GRCz11 22 21868799
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGCATACGACCGCAGGCGAGAGTACCAGCTCTCTGACTCCACTAAATAG[T/C]AAGTGTGTGTGTGTGTGTGTCGTCATTTGCTGCTTTTAGGTTTATTGCTT
Long Flanking Sequence:
ACAATCCCAGCCCTTATCATCGCTTTGATGCGCGTCAAGATGCAAATCAAACCCAGATAGGCCATAAACGTGGCTATAAAAAGCACTACAAGGCTCGCCTGTAAATTTTATTGCTGTCACACCACGGTGAGCTGTCTTTTGTACAGGATTATGGTTAATTATTCCCATGTTTAGTTTTTTTTTGCTTTTAAAGAATCAGTTAATATTTCCTAAAGAAGATCCTTAAAGTTTAACTCCACACGACTTGTGGCCTAGTTGGTTGCGAACTGCTCTGGAAGTCATTAGTATTACACAGCTGTCAAGTCGTAAAATGGGTTGTGTTTTTATTGTGTCTTTATCTGCAGAAAAACGCTCTGCTGGTGCGAGAGGTCGATGTCGAGAAGGTTTGCTCTTTTGAACAGCCCTATGTTGCTGCAATTAATAAGCTCTGGATGGATCCGGGCATCCAGGAAGCATACGACCGCAGGCGAGAGTACCAGCTCTCTGACTCCACTAAATAG[T/C]AAGTGTGTGTGTGTGTGTGTCGTCATTTGCTGCTTTTAGGTTTATTGCTTTTAAAATGAGTCTTTGAATCTCTTTTTGAGGTCAGTTTATGTGTCTGAAAGCATGTCATAGATGGGCAAGTACTGTTTTAAAAGGACATTTCACCCAAAAATTACCTAATTATATAATTAGTCTAAACTTTCAGTTCATTAAAGATTTATAAAGTGATAACTGGATCAAACACAAGTCTTTGAGGGTCAAACAATGAAACAAAGTTGCCTTAAATGGCAAATATTCATTTTTGGGCCACCTATAACTTAAAAGGGATAGTTCACCCAAAAATTAAAAAAAAACTCTATTCACCATCAAGTGGTTGCAAATCTTTGTGTTTTGTTGACAAAAGAAGATATTTTGAAGCATGTTGAAACCTGTCATCCATAATAGGAAAAACATTGATATAAATAATAGGAAAAAAAGATGGTGTAGAATTGTTTAGATTATAATTTTTTGTTTTTAAAAAA
Associated Phenotype:
Not determined