Busch Lab

ZMP

plekhg5

Ensembl ID:
ENSDARG00000025902
ZFIN ID:
ZDB-GENE-060503-766
Description:
Novel protein [Source:UniProtKB/TrEMBL;Acc:Q1LYR1]
Human Orthologue:
PLEKHG5
Human Description:
pleckstrin homology domain containing, family G (with RhoGef domain) member 5 [Source:HGNC Symbol;Ac
Mouse Orthologue:
Plekhg5
Mouse Description:
pleckstrin homology domain containing, family G (with RhoGef domain) member 5 Gene [Source:MGI Symbo

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa41835 Nonsense Mutation detected in F1 DNA Not yet available
sa35079 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa41834 Nonsense Mutation detected in F1 DNA Not yet available
sa31827 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa41835
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067078 Nonsense 40 1135 2 20
ENSDART00000145733 None None 783 None 11
Genomic Location (Zv9):
Chromosome 11 (position 25459252)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 24288077
GRCz11 11 24525693
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACCTGAACAGAAACCCGGCCTCTTGTGTCAGCATCCCAACTGTCCCGAA[C/T]AGCGGCTTGCATCCAAGGTAAGCCATCAGAATGTGTTACAAGGGAAGCCC
Long Flanking Sequence:
GAAACTTTGTTAAAGTGACAGTACCCAGCAAACAATTTTGTGTTTATTAGACATCTAATAGACATCTAAACGTTGACCGCTTGGCTAAAACAAGGCTAAATTTGGGCTGTCAATGAAAATATATAGACATCTAAGAATAGCCTGAAGCTAGACTAGTTGTCAAAAAGACAGATTAGACAGACTTTATATGTGTAGTCATTAATTTCTGTTTATTTAATGAATAGTCTAGATTAGGCCTAGATTAGGATTCTTAGATGTGTATTAGATTTTCACTGACAGCCCAAATTTAGCCTTGTTTTAGCCAAGACAACTATGTTTAGACGTCTATTAGACATCTATTAAATCTCTTTTAAAAACAAATATGCTTGCTGGGTACTTTTAGAGTTTGGCCTACACACACTTCAAGTTGATTTTTAACCTCTATTTATGATATTCCAGGTGAGAAACCTGCACCTGAACAGAAACCCGGCCTCTTGTGTCAGCATCCCAACTGTCCCGAA[C/T]AGCGGCTTGCATCCAAGGTAAGCCATCAGAATGTGTTACAAGGGAAGCCCTGCAGGTGCGACCCAAACTGAAAAATGTACACCTCTTAGTGTTTTTGTGGACAGAAAAATTCCATGTATGCCAATGCATTTATCCCTTGGAATATTCCAGCACAATTAGAGTTTGTCAGCATGTGAGCTTTGGGAACTATCAGGAAAAACAAATGTTTTGTTTGTCTTTGTGCTGTTGAAAGTTCAGAGGCGAGAGAACGGATGTGATGTTATAGGTGGCATTTCACCAGCATTCTCCTGGGAGTCTAGGCAAGCGGGCATGGAAAACAGAGATTACTGCTACCATGTACTGTAGGGTATATGAGGCTCACAAAACACAACATGTTTCTCCCTTCCTGTCTTTCTCTCTCTTCTTATGCTTCTCTCTTTTTGTCTGTTAAAATACAATACATCTATTCTGGTGACACTTTTTTGATTGCATTTTATTGTCATGGGTTCGCTGCCAAACTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35079
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067078 Essential Splice Site 177 1135 6 20
ENSDART00000145733 None None 783 None 11
Genomic Location (Zv9):
Chromosome 11 (position 25437131)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 24265956
GRCz11 11 24503572
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTGAGGTCAGCATGGAGATCGTCCCAGCCGTGAAGAAGAAAACCTTGAG[G/A]TGATTTTGTGCTTGAGCCCCTAGGGGGTGCAATAAACTAATCGATGTATT
Long Flanking Sequence:
CTTGAACCCCCCCCCCCCCCCCCCCCCCCCCCGGCTTTTTCATTATAAAATACCACAAACAAACACTGCACATGGCCTTCACCATCACTCAACTTCAATCATTACCTATTCTTCTGTGCTTTAGGGATCGCAGGAGTGGAGGAATGAAACTGGTTAAAAAGAAGACCAGACGTCGACACACAGATGTAAGAAAAGTACTAGAGCTCTGATTTTCATTAAGACTGTGTATCGCTTTTCTGTCTCAAGCAAATGATCTAGTTTTGCAGGCAAGATTTTGAGGCATTATGTATCCATGAGTCAGTGCTCTTGACCTTTCTTTGTCTGAAAGTAGTCTGTATTGGCAGTAACTGATAGCTTTTATAAATTGTTCTAAAGCAAAAGCTGATTGTCCGTTCTCCACCCCTGCAGGACCCCAGCAAGGAGTGCTTCACTCTGAAGTTTGACTTAAATTTTGAGGTCAGCATGGAGATCGTCCCAGCCGTGAAGAAGAAAACCTTGAG[G/A]TGATTTTGTGCTTGAGCCCCTAGGGGGTGCAATAAACTAATCGATGTATTCAGAGTCATGGTTAGCTGACTGTTAGCTTGTTGTGTTTCAGAGAAGTGCTGGGAGCTGTGTTTGAAAGAAAAGGCATTGAGCTGTCACGTGTAAACCTGTTCCTGGATCAGTCCAATACACCGCTTTCACTGGGATTTGAAGCCTACCGCTTTGGTGGCCACTACCTCAGAGTACGAGGTAATTCACTGCTTACTTTTGAGGGCTGGTAGTCTAAATTAAATTAAAAAACTGAAGCATCTCAAAATTTGGTAACACTTTATAATAATGGTTCATAGTTAATGTATTTACTTGACTAAGTATGAATAATCTTGTAAAGCATTTATTAGTCATAGTTCAACATTATTTAATGCAATATTAAAATCTAAATTGTGCTTTTTAATATTAGTTTATGCACTGTAACTTAACATGATTTAAATAAATAACATTAACTAATATTAACTAACATTAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41834
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067078 Nonsense 388 1135 10 20
ENSDART00000145733 Nonsense 36 783 1 11
Genomic Location (Zv9):
Chromosome 11 (position 25417356)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 24246181
GRCz11 11 24483797
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GATTACCCAAGATGCCTCCGCAGCTCTCGTTCCACAGAGACTCTTGGGAA[G/T]AGGAGCCCAATCTGGAGCTTGAAGAGAGCTGGAAGCAGCTTTTGGAGAAT
Long Flanking Sequence:
TAAATTATTATATATTTGATATTATATGCTTTATTCGAAATATATAACAAAGTTTAGCTACAGTATAACTATCCTGATGTTTAATCTTTATTCAAATGCAGTCACTTTCATAAAGTGTCAACAAAATAAAATAAAAAAACTTAAATTGTTTACATAATTTGCGAATAAATATGATACAATATTAGATAATTTTGCTGTTTATTTGTTGCAGTTTTTTGTAGGTTATTAGTGATTTACGGGAGATTTGGTGTGCCACTGCTTCTTATATTGAAGCAAAATAATGTTTTACATTTTTAGTTTGCAGATTTGAACCAGAAATCTATGAAAGTTCACTTGCTGCAATAAGTTTCTCATATGAATTATATTTGATTTCCTCTCCGCATTTCTCTTTTCAGGAGTGTGATCGTGTAGAGCAGCTGCAGAGTAAGTTATACTCATACACCATGTTTGGATTACCCAAGATGCCTCCGCAGCTCTCGTTCCACAGAGACTCTTGGGAA[G/T]AGGAGCCCAATCTGGAGCTTGAAGAGAGCTGGAAGCAGCTTTTGGAGAATCCTGAGGTGAACACACTTTCCTTTCTTTCGCAGGACTATAGTATTTTTATATTTTATTAGCAGGTCATAATAACCCATAATAAATCATGAATCAACGTCATCTGACTTCATTATGCAATGATAAAAGCGGTCAGACTGATGGCTGTAATCAGTTATGAATGGTTTTATGGTGTTTCTGTTGTAGAAATGAATGTTTTATTGCTCTTGTCATGATCGGTTTTATAATAAGAGTAACTCTTTCAGCTTTAAAGACGTAAAGTACTACTGATTTTAACACAGATGACCCTTCTGTTTTTTATTACATATTATCATCACCATGAAAGAGATGAACTCATAAAATTAAGATGAAGAATATACCATATACATAATGTTTGCAACTCACTTGTATGTATTATGTATACTGTATATAGTTAAAGGCAACAATACTATGCCCTACAACACATTACAACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31827
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067078 Nonsense 860 1135 19 20
ENSDART00000145733 Nonsense 508 783 10 11
Genomic Location (Zv9):
Chromosome 11 (position 25405599)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 24234424
GRCz11 11 24472040
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACTCGCTGCTGTCTGATGACTCCTTTTCCACCAGCGACAGCAAAACTCTA[C/T]AAGCTCTGGGGGATTTAATCGTTACAGATTTAGATCCAGAAAGTCGCTCG
Long Flanking Sequence:
ATATTTTACAATAGGCACTATTCTTATGAATAAACTGCACAGTTGATATCTAAACAACTATATTCTCGACAAAAAAGCCTCAAAAGTACATTTTGTTGTCTAACAACAGTAATATTTGTCAAACTGTAGCGTCTCTGCTTGTTGCTGTCTGTATGTGGGCGGAGTAATACACAGTGAAGGGTGAAGAGGCCATTGTGTGATGTTACTGGCAAAATATTGCATGGCTATCAGCCAATCAGCTTCAATAACCAGACAGAACTGTTGTATAAATATATTTGTAAATATAAATATAATTGTTACTCAAACTAAAGTGTTGTCTAATTTTCTTTTCCCAAAGCCTCTCTCTTTCACCGAGTCACTCTGATGGCTCCACTGAAACTCTTTCTGTTGCTGCCATGGATGAAGTAGATGAAGTAGTCGGCTCAACTGTTCAAACAGCATCCATGAGAAACTCGCTGCTGTCTGATGACTCCTTTTCCACCAGCGACAGCAAAACTCTA[C/T]AAGCTCTGGGGGATTTAATCGTTACAGATTTAGATCCAGAAAGTCGCTCGCTCTCAATTGACAGTGCGTATGGGACTCTCTCACCACAGTCTATGATCACAGAGCTCGACCTAAAGGGAGGCGTCTGCCAGAGTGAAGGAGAGGAAACCGATGCTGGAGAAGAAGAAGAAGCTTTCGAGGATGATGAAGATGATGACGATGATGGGGATGATTCAATAACCTGGAATGGCTCTCAGATTACTGTAAACGAGTCTTACATTTTAGATACAAACAGTGAGGAGCTCAACCGGAGGAATGATTTTTCTGGGATGGCTCAGGTTGTTGCTGGTTGTCGTTCGCAAACTTTGCGGCGCCGTTCTCCTGTTCAACCCCGTCCAGATTACCTGCAGCACTTTACTCTCAGGTCCCGTTCAGAAGATGACCTCCTTCAATGCCTGACCGACCCTCTTCTTCTTCGCCCTACAGGGAAAAACAACGTCAGCAAAAGTTTGACGCACCTC
Associated Phenotype:
Not determined